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The map label for this gene is yclF [H]

Identifier: 183221254

GI number: 183221254

Start: 1961265

End: 1962596

Strand: Reverse

Name: yclF [H]

Synonym: LEPBI_I1870

Alternate gene names: 183221254

Gene position: 1962596-1961265 (Counterclockwise)

Preceding gene: 183221255

Following gene: 183221247

Centisome position: 54.52

GC content: 41.44

Gene sequence:

>1332_bases
ATGTGGGAAAGGCTCAGTTATTATGGGATGCGTGCTCTGCTTGTATTGTATCTTGTTAAGTCACTTGGTTTTTCTGATAG
GGATGCCGGTACTGTTTATGCCTATTATACAAGTTTTGTTTACCTAACACCTGTGATTGGAGGATACATTACCGATCGGT
ATCTCAGTTACAAATTTGCAATTTATCTGGGAAGTGTGCTTATGTTACTCGGTCACCTTTCCCTTGCGATGCCAAATATT
CATTATTTTTATTTTGGGTTATGTTTGTTAGCACTCGGAAATGGTTTTTTTAAACCCAATATTTCCACGATCTTTGGTCG
TTTGTATACGAATACACCAAACCTGCGGGATAGTGGATTTACGATTTTTTATATGGGGATTAATTTGGGGGGCCTACTTG
GTCCGATCATTGCCGGAAGTTTAGGGGAGAAGGTCGATTGGCATTTAGGTTTTTTTTCGGCAGGTGTTGGTATGGGTATT
GGTATCCTCGTTTTTTATTTTGGAAGTCGTTCCTTGCCAGAATCCATTTGGGCCAAAACAGAAAATAGAAACCACCATAC
ACAAGTTTCCATGGGATCCAATCCGCAAAACTTGGCATCCCATTCCAAGGAAACCAATGGGGAGACCGATACCATTTCAA
AAATAACACTCATTGGGCTTCTTAGTTTTTTTAGTATTTTCTTTTGGATGGCATTTGAACAGATGGGAACCTCTCTCAAT
TTATTTGCCTTACGCAATACCGATCGTTTTTTCTTTGGTTGGGAAATCCCAGCCTCCCTCTTACAGTCGTTAAACCCTCT
GATGATCCTTGTCTTTGGTCCTCTTCTTTCTTTCCTTTGGTTCACTCTTTCCAAAACAAACAAAAATCCCAATCCCATTC
TCAAATTTGTGATCAGTTTGTTTTTATTAGGGATCGGATTTTTAGTCATGGTGTTTGCAGCGGAACAAGCAGAGAAAGGG
ATGGTTGTCTCCATTCTCTTTTTAGTGTCTGTTTACTTTTGGAACACTCTCAGTGAGCTCTGTCTCTCACCGGTTGGACT
GTCCTTTGTGAGTCAAATGGCGCCCGTTCGGTTTGCGTCACTTCTGATGGGGATTTGGTTTTTGAGTACGGCTTTTGGTC
ATTATGCCGCGGGAATCCTTTCTGGTTACCAAAGGGAATGGGGGAGTATGGCGCAGTTTTATGCTTTTTTTGTTTTGGTA
TCTTGGTCTGCCGCGATTGTATTATGTGGGATCTATTTTTGGAAACGAACTTCCATCTTATGGTTAATCAATGATACGAA
CCAAACGAAGGACGACGATGGTTCCCCCATACGAGCATCGGTGGAATCGTAA

Upstream 100 bases:

>100_bases
TGAATTTATCCCTAGGGCATGAGGAAACCATCTGGAAAAGCCGGACCAAATCAAATTAGAAGTTCATCCGAGAGGGATCA
CGAGTTTATTTCTCACTGAG

Downstream 100 bases:

>100_bases
CCCAACTCCTTCGGTGGTCAACTAACCTTTGGTTTCTAAAACAAGTTTTTCAATCTCATCGAACTTTTCTTCGCCTGCGA
GGGAAATCACTTGTTCTGCT

Product: major facilitator superfamily permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MWERLSYYGMRALLVLYLVKSLGFSDRDAGTVYAYYTSFVYLTPVIGGYITDRYLSYKFAIYLGSVLMLLGHLSLAMPNI
HYFYFGLCLLALGNGFFKPNISTIFGRLYTNTPNLRDSGFTIFYMGINLGGLLGPIIAGSLGEKVDWHLGFFSAGVGMGI
GILVFYFGSRSLPESIWAKTENRNHHTQVSMGSNPQNLASHSKETNGETDTISKITLIGLLSFFSIFFWMAFEQMGTSLN
LFALRNTDRFFFGWEIPASLLQSLNPLMILVFGPLLSFLWFTLSKTNKNPNPILKFVISLFLLGIGFLVMVFAAEQAEKG
MVVSILFLVSVYFWNTLSELCLSPVGLSFVSQMAPVRFASLLMGIWFLSTAFGHYAAGILSGYQREWGSMAQFYAFFVLV
SWSAAIVLCGIYFWKRTSILWLINDTNQTKDDDGSPIRASVES

Sequences:

>Translated_443_residues
MWERLSYYGMRALLVLYLVKSLGFSDRDAGTVYAYYTSFVYLTPVIGGYITDRYLSYKFAIYLGSVLMLLGHLSLAMPNI
HYFYFGLCLLALGNGFFKPNISTIFGRLYTNTPNLRDSGFTIFYMGINLGGLLGPIIAGSLGEKVDWHLGFFSAGVGMGI
GILVFYFGSRSLPESIWAKTENRNHHTQVSMGSNPQNLASHSKETNGETDTISKITLIGLLSFFSIFFWMAFEQMGTSLN
LFALRNTDRFFFGWEIPASLLQSLNPLMILVFGPLLSFLWFTLSKTNKNPNPILKFVISLFLLGIGFLVMVFAAEQAEKG
MVVSILFLVSVYFWNTLSELCLSPVGLSFVSQMAPVRFASLLMGIWFLSTAFGHYAAGILSGYQREWGSMAQFYAFFVLV
SWSAAIVLCGIYFWKRTSILWLINDTNQTKDDDGSPIRASVES
>Mature_443_residues
MWERLSYYGMRALLVLYLVKSLGFSDRDAGTVYAYYTSFVYLTPVIGGYITDRYLSYKFAIYLGSVLMLLGHLSLAMPNI
HYFYFGLCLLALGNGFFKPNISTIFGRLYTNTPNLRDSGFTIFYMGINLGGLLGPIIAGSLGEKVDWHLGFFSAGVGMGI
GILVFYFGSRSLPESIWAKTENRNHHTQVSMGSNPQNLASHSKETNGETDTISKITLIGLLSFFSIFFWMAFEQMGTSLN
LFALRNTDRFFFGWEIPASLLQSLNPLMILVFGPLLSFLWFTLSKTNKNPNPILKFVISLFLLGIGFLVMVFAAEQAEKG
MVVSILFLVSVYFWNTLSELCLSPVGLSFVSQMAPVRFASLLMGIWFLSTAFGHYAAGILSGYQREWGSMAQFYAFFVLV
SWSAAIVLCGIYFWKRTSILWLINDTNQTKDDDGSPIRASVES

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI226371746, Length=334, Percent_Identity=30.2395209580838, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI4827008, Length=366, Percent_Identity=24.8633879781421, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI226371748, Length=323, Percent_Identity=28.7925696594427, Blast_Score=95, Evalue=2e-19,
Organism=Escherichia coli, GI1790572, Length=422, Percent_Identity=30.5687203791469, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI1786927, Length=424, Percent_Identity=29.0094339622642, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1787922, Length=418, Percent_Identity=29.9043062200957, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1789911, Length=421, Percent_Identity=29.4536817102138, Blast_Score=163, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17569141, Length=389, Percent_Identity=22.6221079691517, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71987453, Length=338, Percent_Identity=25.1479289940828, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17541704, Length=333, Percent_Identity=26.7267267267267, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28571098, Length=341, Percent_Identity=30.2052785923754, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28571102, Length=341, Percent_Identity=30.791788856305, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI28571100, Length=341, Percent_Identity=30.791788856305, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24639585, Length=318, Percent_Identity=28.9308176100629, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24639583, Length=318, Percent_Identity=28.9308176100629, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24639581, Length=318, Percent_Identity=28.9308176100629, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 49640; Mature: 49640

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS50850 MFS ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWERLSYYGMRALLVLYLVKSLGFSDRDAGTVYAYYTSFVYLTPVIGGYITDRYLSYKFA
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYLGSVLMLLGHLSLAMPNIHYFYFGLCLLALGNGFFKPNISTIFGRLYTNTPNLRDSGF
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCE
TIFYMGINLGGLLGPIIAGSLGEKVDWHLGFFSAGVGMGIGILVFYFGSRSLPESIWAKT
EEEEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCC
ENRNHHTQVSMGSNPQNLASHSKETNGETDTISKITLIGLLSFFSIFFWMAFEQMGTSLN
CCCCCCEEEECCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
LFALRNTDRFFFGWEIPASLLQSLNPLMILVFGPLLSFLWFTLSKTNKNPNPILKFVISL
EEEEECCCCEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
FLLGIGFLVMVFAAEQAEKGMVVSILFLVSVYFWNTLSELCLSPVGLSFVSQMAPVRFAS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LLMGIWFLSTAFGHYAAGILSGYQREWGSMAQFYAFFVLVSWSAAIVLCGIYFWKRTSIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
WLINDTNQTKDDDGSPIRASVES
EEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MWERLSYYGMRALLVLYLVKSLGFSDRDAGTVYAYYTSFVYLTPVIGGYITDRYLSYKFA
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYLGSVLMLLGHLSLAMPNIHYFYFGLCLLALGNGFFKPNISTIFGRLYTNTPNLRDSGF
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCE
TIFYMGINLGGLLGPIIAGSLGEKVDWHLGFFSAGVGMGIGILVFYFGSRSLPESIWAKT
EEEEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCC
ENRNHHTQVSMGSNPQNLASHSKETNGETDTISKITLIGLLSFFSIFFWMAFEQMGTSLN
CCCCCCEEEECCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
LFALRNTDRFFFGWEIPASLLQSLNPLMILVFGPLLSFLWFTLSKTNKNPNPILKFVISL
EEEEECCCCEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
FLLGIGFLVMVFAAEQAEKGMVVSILFLVSVYFWNTLSELCLSPVGLSFVSQMAPVRFAS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LLMGIWFLSTAFGHYAAGILSGYQREWGSMAQFYAFFVLVSWSAAIVLCGIYFWKRTSIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
WLINDTNQTKDDDGSPIRASVES
EEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]