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The map label for this gene is ywlC [H]

Identifier: 183221225

GI number: 183221225

Start: 1930618

End: 1931574

Strand: Reverse

Name: ywlC [H]

Synonym: LEPBI_I1839

Alternate gene names: 183221225

Gene position: 1931574-1930618 (Counterclockwise)

Preceding gene: 183221226

Following gene: 183221223

Centisome position: 53.66

GC content: 42.63

Gene sequence:

>957_bases
GTGGTTGTATTTCCCACAGAAACCGTATTTGGAATTGGTGCGGCAAGTGACAACGAAGATGCCTGTTTACGGATTTACCA
AATCAAAGGAAGGCCAAGTGATAATCCTCTTATCGCCCATTTTTCCTCCATCGATGCAATCAAAAAAGTCTGTTATGTGA
ATGAGGTCGCCAATCAGTTATTATGCGAATTTTCCCCTGGTCCATTTACCTTGGTTTTACCAAAAACTGATCCAAAGATC
TTTCCAAAGCAGTTACCTACCTTAGCCGTTCGGATTCCGAAAAACCCAGTCATCCGCGAGTGGATTGAAGCATGCGGGTC
ACCCATCTCCGCACCTTCCGCCAACCTTTCAGGAAGGCCTTCCCTTACTCGCATGACAGATGTTGTGCGTTACTTTGATG
GAATTGTGGATGGAATTTTGATCGCTGAAGAACCAAACTTAGGAATTGAATCCACAGTGCTTGGACTCACGACCGAAGTT
CCCGTTCTCCTTCGGCCAGGTTCCATCGAATCACAGGCCTTAAGACGGTTTTTGCCAAATTTAGTGATTCCAAACGAAAT
CAAATCCAAAGATTCCAAATCCGAGGATTCCAAAACAAATCAATCCTTTGTCCCTTTGAGTCCAGGAATGAAATACAAAC
ACTATGCCCCCAACGCAAAAGTGGTTTTACTTGAGACAGAGATTTTTTTATCAACATTTTCAAAACAAGGGATGGATCCT
AAATTCGCTTGGATTGGGTTTTCCTTTGGTTCAAAAACTTTGCCGGAAGTGTTAGGAGGAAATCGAGTTTTGTGTGTTGC
AAATAACATTGACTATATGGCAAAACTCTATGCGTTTTTTGAATCCTGTGATTTAGAAGGCTACAATCGAATTTATTGTG
AAATGCCACGAGAGGAAGAAGGAAGGGAAGGCCTTCTCAATCGATTGGAAAAGGCTGCTGCTACGAGTTTCGAGTAA

Upstream 100 bases:

>100_bases
TCCAAACCAAAATCCAAATCAAAAACCAAACAGTTTTAAAATGAAAACTCTTATCTCTTCGGATGTTCGTTTGCTTGCGG
ACCTCATCCGAAAGGGAGGA

Downstream 100 bases:

>100_bases
AAGATTGGATAGGATAAAATTACCAAACTCCCTAACCATTTGATTTTCCCTGTCCGATCTAACTTCCATCCCTTCAAAAC
CAATCACTTTTGTCTGCCAG

Product: putative translation factor SUA5

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MVVFPTETVFGIGAASDNEDACLRIYQIKGRPSDNPLIAHFSSIDAIKKVCYVNEVANQLLCEFSPGPFTLVLPKTDPKI
FPKQLPTLAVRIPKNPVIREWIEACGSPISAPSANLSGRPSLTRMTDVVRYFDGIVDGILIAEEPNLGIESTVLGLTTEV
PVLLRPGSIESQALRRFLPNLVIPNEIKSKDSKSEDSKTNQSFVPLSPGMKYKHYAPNAKVVLLETEIFLSTFSKQGMDP
KFAWIGFSFGSKTLPEVLGGNRVLCVANNIDYMAKLYAFFESCDLEGYNRIYCEMPREEEGREGLLNRLEKAAATSFE

Sequences:

>Translated_318_residues
MVVFPTETVFGIGAASDNEDACLRIYQIKGRPSDNPLIAHFSSIDAIKKVCYVNEVANQLLCEFSPGPFTLVLPKTDPKI
FPKQLPTLAVRIPKNPVIREWIEACGSPISAPSANLSGRPSLTRMTDVVRYFDGIVDGILIAEEPNLGIESTVLGLTTEV
PVLLRPGSIESQALRRFLPNLVIPNEIKSKDSKSEDSKTNQSFVPLSPGMKYKHYAPNAKVVLLETEIFLSTFSKQGMDP
KFAWIGFSFGSKTLPEVLGGNRVLCVANNIDYMAKLYAFFESCDLEGYNRIYCEMPREEEGREGLLNRLEKAAATSFE
>Mature_318_residues
MVVFPTETVFGIGAASDNEDACLRIYQIKGRPSDNPLIAHFSSIDAIKKVCYVNEVANQLLCEFSPGPFTLVLPKTDPKI
FPKQLPTLAVRIPKNPVIREWIEACGSPISAPSANLSGRPSLTRMTDVVRYFDGIVDGILIAEEPNLGIESTVLGLTTEV
PVLLRPGSIESQALRRFLPNLVIPNEIKSKDSKSEDSKTNQSFVPLSPGMKYKHYAPNAKVVLLETEIFLSTFSKQGMDP
KFAWIGFSFGSKTLPEVLGGNRVLCVANNIDYMAKLYAFFESCDLEGYNRIYCEMPREEEGREGLLNRLEKAAATSFE

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=135, Percent_Identity=34.0740740740741, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87081864, Length=175, Percent_Identity=24, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321269, Length=242, Percent_Identity=36.7768595041322, Blast_Score=142, Evalue=5e-35,
Organism=Drosophila melanogaster, GI78707274, Length=168, Percent_Identity=26.7857142857143, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 35175; Mature: 35175

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVFPTETVFGIGAASDNEDACLRIYQIKGRPSDNPLIAHFSSIDAIKKVCYVNEVANQL
CEEECCCCEEEECCCCCCCCCEEEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
LCEFSPGPFTLVLPKTDPKIFPKQLPTLAVRIPKNPVIREWIEACGSPISAPSANLSGRP
HEECCCCCEEEEEECCCCCCCHHCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCC
SLTRMTDVVRYFDGIVDGILIAEEPNLGIESTVLGLTTEVPVLLRPGSIESQALRRFLPN
CHHHHHHHHHHHHHHHHCEEEECCCCCCCCCEEEEEECCCCEEEECCCCCHHHHHHHCCC
LVIPNEIKSKDSKSEDSKTNQSFVPLSPGMKYKHYAPNAKVVLLETEIFLSTFSKQGMDP
CCCCCHHHCCCCCCCCCCCCCCEEECCCCCCEEEECCCCEEEEEEHHHHHHHHHHCCCCC
KFAWIGFSFGSKTLPEVLGGNRVLCVANNIDYMAKLYAFFESCDLEGYNRIYCEMPREEE
CEEEEEECCCCCHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCC
GREGLLNRLEKAAATSFE
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVVFPTETVFGIGAASDNEDACLRIYQIKGRPSDNPLIAHFSSIDAIKKVCYVNEVANQL
CEEECCCCEEEECCCCCCCCCEEEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
LCEFSPGPFTLVLPKTDPKIFPKQLPTLAVRIPKNPVIREWIEACGSPISAPSANLSGRP
HEECCCCCEEEEEECCCCCCCHHCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCC
SLTRMTDVVRYFDGIVDGILIAEEPNLGIESTVLGLTTEVPVLLRPGSIESQALRRFLPN
CHHHHHHHHHHHHHHHHCEEEECCCCCCCCCEEEEEECCCCEEEECCCCCHHHHHHHCCC
LVIPNEIKSKDSKSEDSKTNQSFVPLSPGMKYKHYAPNAKVVLLETEIFLSTFSKQGMDP
CCCCCHHHCCCCCCCCCCCCCCEEECCCCCCEEEECCCCEEEEEEHHHHHHHHHHCCCCC
KFAWIGFSFGSKTLPEVLGGNRVLCVANNIDYMAKLYAFFESCDLEGYNRIYCEMPREEE
CEEEEEECCCCCHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCC
GREGLLNRLEKAAATSFE
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]