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The map label for this gene is 183221176

Identifier: 183221176

GI number: 183221176

Start: 1868461

End: 1869561

Strand: Reverse

Name: 183221176

Synonym: LEPBI_I1790

Alternate gene names: NA

Gene position: 1869561-1868461 (Counterclockwise)

Preceding gene: 183221181

Following gene: 183221175

Centisome position: 51.94

GC content: 43.51

Gene sequence:

>1101_bases
ATGAAGAAAGTTTACATTCACAATCCATCACTCAGTGTATTCGGTAAACATAAAGGTTCTCAATTAGATTTGTCTTATGC
CACCGCAAAACAATCTGTACATGAGTTTCAATCTCACAAAATTCAGTTCATTATTTATGCAAGTTTTTCACCTGATTCTT
ATAACAAGGAATACCATCTCTCTGCAAAAATAGCAGCAAGGCTCGGTCTCAAAGATGTTTATTCCATTCGGATGGAAACG
GCTTCGTCTTCTGGGGCTTCAGCCTTTCAATTGGGAGTGAATTTAATTCTCAGTGGTCGTTATGATCATGGTCTCGTGAT
TGCAACAGAACTCATGTCACAATTGAATCGTGAGGAAAGTAATTTGTTGTTAGGCTCAGTCCTCTCTGACTCTCAAAAAA
AATTGGGAATGTCAATGGCACAAGGTGGAGCCATGATTACCAATCGTTACCTTCATGAGTATGGATATTCGAAAGAGGAC
TTATTTGCGATTGCGAAAAAACTCCACGACAATGGCCTACAAAATCCAAAAGCCCATATCAAAAAAAATCTAACCATTGA
GGAATACGAAAACCAACCAAAAATCGCGAGTCCCTTGGGTCTCTATGATATATCTCCACTTTCGGATGGTTCTGCGGCTC
TCATTCTTTCAAAGGATCCAAGTTCCATTCTGGTGCGTGGGATGGGATCTGGCACGGCTCCCTTTCTTTCCTCGGCTGAG
CCCAGTTTTTTAGCCAATCGCATTGCCTTTTCCAAAGCATATGAAGGAGCAGGGGTGGACCCAAACGACATTCATTTTGC
GGAATTACACGATGCCTTCACTCCTTTTGAGCTCGTAGGGGCTGAGGATGCTGGTTTTTTCAAACGAGGGGAGGCCCTGT
TCCAAGTTAAAGCTGGTCTCACCCATCCCAAGGGGAAACTTCCTATCAACGCCTCTGGTGGGCTTAAATCGAGGGGTCAT
CCAGTCGGTGCTTCCGGTCTTGCACAGATTGTAGAACTTTGCCGCTTCTTTTCTGAATGGCCCGAAAAGCGGTTGGCAGT
AGCACAAAGTATAGGTGGACTAGCTACAAACAACTTTGTGTCGATATTAGAAAGAGTCTGA

Upstream 100 bases:

>100_bases
TTACTTCTTTATTTCCCTTCATATGGGTGACCTCTTTTTATCGGTTCAATTGGAAAGATAATTGGTTTTCATGGAATAGG
CAAGCGGAAACTATATTCGA

Downstream 100 bases:

>100_bases
TGCCTGAAAAAATACTGATCATCCAAACCGCTTTTTTAGGAGATTTGATCCTATCGACCTCCTTTTTCCATGCTGTGAAA
ATGGAACACAAGGAAAGCGA

Product: putative acetyl-CoA C-acyltransferase

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MKKVYIHNPSLSVFGKHKGSQLDLSYATAKQSVHEFQSHKIQFIIYASFSPDSYNKEYHLSAKIAARLGLKDVYSIRMET
ASSSGASAFQLGVNLILSGRYDHGLVIATELMSQLNREESNLLLGSVLSDSQKKLGMSMAQGGAMITNRYLHEYGYSKED
LFAIAKKLHDNGLQNPKAHIKKNLTIEEYENQPKIASPLGLYDISPLSDGSAALILSKDPSSILVRGMGSGTAPFLSSAE
PSFLANRIAFSKAYEGAGVDPNDIHFAELHDAFTPFELVGAEDAGFFKRGEALFQVKAGLTHPKGKLPINASGGLKSRGH
PVGASGLAQIVELCRFFSEWPEKRLAVAQSIGGLATNNFVSILERV

Sequences:

>Translated_366_residues
MKKVYIHNPSLSVFGKHKGSQLDLSYATAKQSVHEFQSHKIQFIIYASFSPDSYNKEYHLSAKIAARLGLKDVYSIRMET
ASSSGASAFQLGVNLILSGRYDHGLVIATELMSQLNREESNLLLGSVLSDSQKKLGMSMAQGGAMITNRYLHEYGYSKED
LFAIAKKLHDNGLQNPKAHIKKNLTIEEYENQPKIASPLGLYDISPLSDGSAALILSKDPSSILVRGMGSGTAPFLSSAE
PSFLANRIAFSKAYEGAGVDPNDIHFAELHDAFTPFELVGAEDAGFFKRGEALFQVKAGLTHPKGKLPINASGGLKSRGH
PVGASGLAQIVELCRFFSEWPEKRLAVAQSIGGLATNNFVSILERV
>Mature_366_residues
MKKVYIHNPSLSVFGKHKGSQLDLSYATAKQSVHEFQSHKIQFIIYASFSPDSYNKEYHLSAKIAARLGLKDVYSIRMET
ASSSGASAFQLGVNLILSGRYDHGLVIATELMSQLNREESNLLLGSVLSDSQKKLGMSMAQGGAMITNRYLHEYGYSKED
LFAIAKKLHDNGLQNPKAHIKKNLTIEEYENQPKIASPLGLYDISPLSDGSAALILSKDPSSILVRGMGSGTAPFLSSAE
PSFLANRIAFSKAYEGAGVDPNDIHFAELHDAFTPFELVGAEDAGFFKRGEALFQVKAGLTHPKGKLPINASGGLKSRGH
PVGASGLAQIVELCRFFSEWPEKRLAVAQSIGGLATNNFVSILERV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=300, Percent_Identity=28.6666666666667, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI302344760, Length=300, Percent_Identity=28.6666666666667, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI302344767, Length=204, Percent_Identity=32.3529411764706, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI302344762, Length=204, Percent_Identity=32.3529411764706, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI55956775, Length=196, Percent_Identity=30.6122448979592, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17537653, Length=300, Percent_Identity=30.3333333333333, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24585051, Length=369, Percent_Identity=25.7452574525745, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI19921506, Length=303, Percent_Identity=28.0528052805281, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 39723; Mature: 39723

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVYIHNPSLSVFGKHKGSQLDLSYATAKQSVHEFQSHKIQFIIYASFSPDSYNKEYHL
CCEEEEECCCEEEEECCCCCEEEEHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCEEEE
SAKIAARLGLKDVYSIRMETASSSGASAFQLGVNLILSGRYDHGLVIATELMSQLNREES
HHHHHHHHCHHHHHHHHHHCCCCCCCHHHEECEEEEEECCCCCCEEEHHHHHHHHCCCHH
NLLLGSVLSDSQKKLGMSMAQGGAMITNRYLHEYGYSKEDLFAIAKKLHDNGLQNPKAHI
CEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHH
KKNLTIEEYENQPKIASPLGLYDISPLSDGSAALILSKDPSSILVRGMGSGTAPFLSSAE
HCCCCHHHHCCCCCCCCCCCCEECCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCC
PSFLANRIAFSKAYEGAGVDPNDIHFAELHDAFTPFELVGAEDAGFFKRGEALFQVKAGL
HHHHHHHHHHHHHCCCCCCCCCCEEHHHHHCCCCCEEEECCCCCCCHHCCCEEEEEECCC
THPKGKLPINASGGLKSRGHPVGASGLAQIVELCRFFSEWPEKRLAVAQSIGGLATNNFV
CCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHH
SILERV
HHHHCC
>Mature Secondary Structure
MKKVYIHNPSLSVFGKHKGSQLDLSYATAKQSVHEFQSHKIQFIIYASFSPDSYNKEYHL
CCEEEEECCCEEEEECCCCCEEEEHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCEEEE
SAKIAARLGLKDVYSIRMETASSSGASAFQLGVNLILSGRYDHGLVIATELMSQLNREES
HHHHHHHHCHHHHHHHHHHCCCCCCCHHHEECEEEEEECCCCCCEEEHHHHHHHHCCCHH
NLLLGSVLSDSQKKLGMSMAQGGAMITNRYLHEYGYSKEDLFAIAKKLHDNGLQNPKAHI
CEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHH
KKNLTIEEYENQPKIASPLGLYDISPLSDGSAALILSKDPSSILVRGMGSGTAPFLSSAE
HCCCCHHHHCCCCCCCCCCCCEECCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCC
PSFLANRIAFSKAYEGAGVDPNDIHFAELHDAFTPFELVGAEDAGFFKRGEALFQVKAGL
HHHHHHHHHHHHHCCCCCCCCCCEEHHHHHCCCCCEEEECCCCCCCHHCCCEEEEEECCC
THPKGKLPINASGGLKSRGHPVGASGLAQIVELCRFFSEWPEKRLAVAQSIGGLATNNFV
CCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHH
SILERV
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]