| Definition | Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_010602 |
| Length | 3,599,677 |
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The map label for this gene is rsbU [H]
Identifier: 183221154
GI number: 183221154
Start: 1845838
End: 1847658
Strand: Reverse
Name: rsbU [H]
Synonym: LEPBI_I1768
Alternate gene names: 183221154
Gene position: 1847658-1845838 (Counterclockwise)
Preceding gene: 183221155
Following gene: 183221153
Centisome position: 51.33
GC content: 41.3
Gene sequence:
>1821_bases ATGGTTGATTTCAAAGTTTCCAAACGAATGCTCGTCAACTTCCGCGGACAGAACAAAGTTGTGGGAGGATTAACAGATAA AGATAAAATTGCAATCCTCCTTTATATCTCCAAAGAATTTGCCAATTTAGATAGAGAAGACCAACTCTTTGACAAGGTCA TCCTGATTTGCCAGGAGATTTTTGAATCGGACAACACCACACTCCGATTATGGGACGGTGAATTTTTAGTCCCTGTTAAA TTTGTAAAAGAAACCGAACCTCCACGTCGGAATTTAAAAGCAGGAGAAGGGTATTCAGGAACTGTTTTTGAAACCAAAGA ACCGATCCTTGTCAATGACCTTTCCAGATCGGCGCATTACTTTGATGAGGGGGAAAAAACCAAGTCGGTGATGTGTGTTC CCATCATGCAAAAAGAAGAGATCCTCGGAACTCTGGCTGTAGAAAGTGAAAGGGAAAACTTCTACATCATTGATGACTTG GAAATTTTGGAGGCACTCACTTCACAACTGGCACTGGCACTTTATGGTGTGCGCCTCATTGAGGGACTTGTAACTGCTAG GGCACGTGAGGCGGCAATTCTCAATCAATTGGAGTGGGATTTAAAAATGGGACGAAATGTCCAAAGCCAAATCCTACCAC AAGACTTAAGTGCCTGGAATGGAATTTATTTTGCAAGTCACTATGAACCAATGGCTGAGGTCAGTGGGGATTTAGTCGAT ATTGTCAGACAAGGTCATTCTCTCACAGCAATTAACATCGATGTGTCGGGACATGGAATCCCTGCGGCGCTCGTTACTAT GGCCATCCACCATCAGTTCCGACGATCCGTGATGGCAGGGCTTGGTCTCACAGAAATCATGGAAGAACTCGGCGAAAAAT TAAGAGAACAACTTCCTGAATCAACTTATTTCACTGCGTTTATGGTTCGAATCTTTAGTGATTATACCTTTGGGTATGTG AATGCGGGCCACCAACGGATGTTACATTATAAAGCATCTGATGATACCTTCATTCAATATGATACAAAAGGGGTCCCTTT GGGAATCCTTCCTGTCAGAAAAGCAGATTATGAAGAAAAACAAGGTAAACTCGAACCTGGTGATTTTTTACTTTTGATTT CAGATGGTTTTAGTGAACAAAGAAACCACCTTAAAGATGAAGTAGGTGTGGAACGAATCCAAACTTGGTTACACGATGAA AGGGAAAAACTTGTCATCGAAGGGCGAGGAAAAGTGGATTTAAAAAAATTATCTGCTGCCTTTATCAAACGGTTTCGGGC CTACCAAGGGGAAGTTCCCAATGGAGACGATTTGAGTTTTCTCTTTTTGTATTGTGGAGATTCCATTCCGGAAGCTTCCC ATTACATCCAATTGGCAAAACAATCCAATTCCAAAATGAAAATGGAAGAAGCCTATGCCCAAGCGCTCAAAGCCTTTAGC ATCGATTCTTCTTTAAAAGAAATTTTAGTGTTCCTTGGAAAAATGTACTATCGAGACGGAAAATACAAGGAAGCCATTCG GTATTTAGAAGAGTATCTCCGCACTTCTGGTGATAATACTGCCGCTTCTCACTTTACCATGGGTCGAGCCTATTACAAGG CAGGGATGATTTCGGAAGCGAAACGGGCTTTGAAGATGGCCCTGTCGAGTGACCATAGTTTTGCGAAAGCAAGTATTTTG TTGGCACAATGTTATTTGAAAGAAAATGCGAAACCAAAAGCGATTAAGGTATTACAACAAGGCGTAAAAAACACCCCTCA AAGTTTGGAATTAAAAACCTCTCTTTTGAGATTAGAATCACATACACAAAAAGTGAGTTAA
Upstream 100 bases:
>100_bases ATTCCATCCAGTTTGTAGAGAAATATAGGATATTTTAACTTCTTTAGGCGAGATGCATCGTCGGTACGATACTTGCATCT AAAGGTGAAAGGTATCCAAT
Downstream 100 bases:
>100_bases GGAAAGTTATATGAAACATTTCGGAATCTATTTTACATTGATGGCCCTATTTTTGGTCAGCGTGCTGAACGCTGAGTCTC TTGAGAACGGGGAAAAGGAA
Product: TPR repeat-containing protein
Products: NA
Alternate protein names: Sigma factor sigB regulation protein rsbU [H]
Number of amino acids: Translated: 606; Mature: 606
Protein sequence:
>606_residues MVDFKVSKRMLVNFRGQNKVVGGLTDKDKIAILLYISKEFANLDREDQLFDKVILICQEIFESDNTTLRLWDGEFLVPVK FVKETEPPRRNLKAGEGYSGTVFETKEPILVNDLSRSAHYFDEGEKTKSVMCVPIMQKEEILGTLAVESERENFYIIDDL EILEALTSQLALALYGVRLIEGLVTARAREAAILNQLEWDLKMGRNVQSQILPQDLSAWNGIYFASHYEPMAEVSGDLVD IVRQGHSLTAINIDVSGHGIPAALVTMAIHHQFRRSVMAGLGLTEIMEELGEKLREQLPESTYFTAFMVRIFSDYTFGYV NAGHQRMLHYKASDDTFIQYDTKGVPLGILPVRKADYEEKQGKLEPGDFLLLISDGFSEQRNHLKDEVGVERIQTWLHDE REKLVIEGRGKVDLKKLSAAFIKRFRAYQGEVPNGDDLSFLFLYCGDSIPEASHYIQLAKQSNSKMKMEEAYAQALKAFS IDSSLKEILVFLGKMYYRDGKYKEAIRYLEEYLRTSGDNTAASHFTMGRAYYKAGMISEAKRALKMALSSDHSFAKASIL LAQCYLKENAKPKAIKVLQQGVKNTPQSLELKTSLLRLESHTQKVS
Sequences:
>Translated_606_residues MVDFKVSKRMLVNFRGQNKVVGGLTDKDKIAILLYISKEFANLDREDQLFDKVILICQEIFESDNTTLRLWDGEFLVPVK FVKETEPPRRNLKAGEGYSGTVFETKEPILVNDLSRSAHYFDEGEKTKSVMCVPIMQKEEILGTLAVESERENFYIIDDL EILEALTSQLALALYGVRLIEGLVTARAREAAILNQLEWDLKMGRNVQSQILPQDLSAWNGIYFASHYEPMAEVSGDLVD IVRQGHSLTAINIDVSGHGIPAALVTMAIHHQFRRSVMAGLGLTEIMEELGEKLREQLPESTYFTAFMVRIFSDYTFGYV NAGHQRMLHYKASDDTFIQYDTKGVPLGILPVRKADYEEKQGKLEPGDFLLLISDGFSEQRNHLKDEVGVERIQTWLHDE REKLVIEGRGKVDLKKLSAAFIKRFRAYQGEVPNGDDLSFLFLYCGDSIPEASHYIQLAKQSNSKMKMEEAYAQALKAFS IDSSLKEILVFLGKMYYRDGKYKEAIRYLEEYLRTSGDNTAASHFTMGRAYYKAGMISEAKRALKMALSSDHSFAKASIL LAQCYLKENAKPKAIKVLQQGVKNTPQSLELKTSLLRLESHTQKVS >Mature_606_residues MVDFKVSKRMLVNFRGQNKVVGGLTDKDKIAILLYISKEFANLDREDQLFDKVILICQEIFESDNTTLRLWDGEFLVPVK FVKETEPPRRNLKAGEGYSGTVFETKEPILVNDLSRSAHYFDEGEKTKSVMCVPIMQKEEILGTLAVESERENFYIIDDL EILEALTSQLALALYGVRLIEGLVTARAREAAILNQLEWDLKMGRNVQSQILPQDLSAWNGIYFASHYEPMAEVSGDLVD IVRQGHSLTAINIDVSGHGIPAALVTMAIHHQFRRSVMAGLGLTEIMEELGEKLREQLPESTYFTAFMVRIFSDYTFGYV NAGHQRMLHYKASDDTFIQYDTKGVPLGILPVRKADYEEKQGKLEPGDFLLLISDGFSEQRNHLKDEVGVERIQTWLHDE REKLVIEGRGKVDLKKLSAAFIKRFRAYQGEVPNGDDLSFLFLYCGDSIPEASHYIQLAKQSNSKMKMEEAYAQALKAFS IDSSLKEILVFLGKMYYRDGKYKEAIRYLEEYLRTSGDNTAASHFTMGRAYYKAGMISEAKRALKMALSSDHSFAKASIL LAQCYLKENAKPKAIKVLQQGVKNTPQSLELKTSLLRLESHTQKVS
Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]
COG id: COG2208
COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PP2C-like domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR017944 - InterPro: IPR001932 - InterPro: IPR014787 - InterPro: IPR010822 - ProDom: PD685490 [H]
Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]
EC number: =3.1.3.3 [H]
Molecular weight: Translated: 68711; Mature: 68711
Theoretical pI: Translated: 6.41; Mature: 6.41
Prosite motif: PS50005 TPR ; PS50293 TPR_REGION
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVDFKVSKRMLVNFRGQNKVVGGLTDKDKIAILLYISKEFANLDREDQLFDKVILICQEI CCCCCCCHHHEEEECCCCCEECCCCCCCCEEEEEEEEHHHHCCCCHHHHHHHHHHHHHHH FESDNTTLRLWDGEFLVPVKFVKETEPPRRNLKAGEGYSGTVFETKEPILVNDLSRSAHY HCCCCCEEEEECCCEEEEEHHHHCCCCCCCCCCCCCCCCCCEEECCCCEEEECHHHHHHH FDEGEKTKSVMCVPIMQKEEILGTLAVESERENFYIIDDLEILEALTSQLALALYGVRLI CCCCCCCCCEEEEECCCHHHHHHHHEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH EGLVTARAREAAILNQLEWDLKMGRNVQSQILPQDLSAWNGIYFASHYEPMAEVSGDLVD HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHCCCEEEECCCCCHHHHCHHHHH IVRQGHSLTAINIDVSGHGIPAALVTMAIHHQFRRSVMAGLGLTEIMEELGEKLREQLPE HHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC STYFTAFMVRIFSDYTFGYVNAGHQRMLHYKASDDTFIQYDTKGVPLGILPVRKADYEEK CHHHHHHHHHHHHCCCCEEECCCCCEEEEEECCCCCEEEECCCCCCEEEECCCCCCCHHH QGKLEPGDFLLLISDGFSEQRNHLKDEVGVERIQTWLHDEREKLVIEGRGKVDLKKLSAA CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHH FIKRFRAYQGEVPNGDDLSFLFLYCGDSIPEASHYIQLAKQSNSKMKMEEAYAQALKAFS HHHHHHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHC IDSSLKEILVFLGKMYYRDGKYKEAIRYLEEYLRTSGDNTAASHFTMGRAYYKAGMISEA CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHH KRALKMALSSDHSFAKASILLAQCYLKENAKPKAIKVLQQGVKNTPQSLELKTSLLRLES HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH HTQKVS HHHCCC >Mature Secondary Structure MVDFKVSKRMLVNFRGQNKVVGGLTDKDKIAILLYISKEFANLDREDQLFDKVILICQEI CCCCCCCHHHEEEECCCCCEECCCCCCCCEEEEEEEEHHHHCCCCHHHHHHHHHHHHHHH FESDNTTLRLWDGEFLVPVKFVKETEPPRRNLKAGEGYSGTVFETKEPILVNDLSRSAHY HCCCCCEEEEECCCEEEEEHHHHCCCCCCCCCCCCCCCCCCEEECCCCEEEECHHHHHHH FDEGEKTKSVMCVPIMQKEEILGTLAVESERENFYIIDDLEILEALTSQLALALYGVRLI CCCCCCCCCEEEEECCCHHHHHHHHEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH EGLVTARAREAAILNQLEWDLKMGRNVQSQILPQDLSAWNGIYFASHYEPMAEVSGDLVD HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHCCCEEEECCCCCHHHHCHHHHH IVRQGHSLTAINIDVSGHGIPAALVTMAIHHQFRRSVMAGLGLTEIMEELGEKLREQLPE HHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC STYFTAFMVRIFSDYTFGYVNAGHQRMLHYKASDDTFIQYDTKGVPLGILPVRKADYEEK CHHHHHHHHHHHHCCCCEEECCCCCEEEEEECCCCCEEEECCCCCCEEEECCCCCCCHHH QGKLEPGDFLLLISDGFSEQRNHLKDEVGVERIQTWLHDEREKLVIEGRGKVDLKKLSAA CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHH FIKRFRAYQGEVPNGDDLSFLFLYCGDSIPEASHYIQLAKQSNSKMKMEEAYAQALKAFS HHHHHHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHC IDSSLKEILVFLGKMYYRDGKYKEAIRYLEEYLRTSGDNTAASHFTMGRAYYKAGMISEA CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHH KRALKMALSSDHSFAKASILLAQCYLKENAKPKAIKVLQQGVKNTPQSLELKTSLLRLES HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH HTQKVS HHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]