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The map label for this gene is zraR [H]

Identifier: 183220973

GI number: 183220973

Start: 1660857

End: 1662137

Strand: Reverse

Name: zraR [H]

Synonym: LEPBI_I1586

Alternate gene names: 183220973

Gene position: 1662137-1660857 (Counterclockwise)

Preceding gene: 183220974

Following gene: 183220972

Centisome position: 46.17

GC content: 34.04

Gene sequence:

>1281_bases
ATGGTGGAACCAATCGAACCAACAAATCCGACTGTTTCAAAAACAGAACACTTACGTAGACCGAAGGAACCGATTTTAAT
CATCGAAGATAAACGAGAAAATCAAGTTCTTTTAGAAGGAATCTGTAAGCGAATTGGAGCAACTTACGAAGTTGCTGAAA
ATGGAAAAATCGCTCTAGAAATGGCTAAAATGAAGTCGTTTAGCCTCTATTTGGTGGATCTGATGATGCCTATCATGGAT
GGCAAAACTTTCATCACTGAACAAAGGAAAATCGAACCACGCGCTGTATTTATCGTCCAGACAGCCATTGATCAAACAGA
AGAAATCATCGAAATCATGAAAATGGGAGTTTATGATTATTTAATCAAACCCCTCCACGTAGAAATTGTAGCAGACCGTC
TGGAAAAAACATTAGAATACGTCTATTTAAAAAGAATGGAAGCAGTTCTCATCGACGAAGAATCGAAAGAATTAAAAAGC
CAACTTGAATGGCTCAATTATAAAGAATCCCATCGTAAAACAAATGAAGTCAACGCAGAACTGAATTCCATTCTAAACTT
AAAAACAACCTTGATGCAAGGGTCTGGCATAGGAGCAATGACTACTATCATTGACTCTATTGAGACAATCAAAAAAGCTG
AAAACGGAAATTATCTCATTCCAAAAGAGTATTGGGATATTATTTCAGAGAATCAAGAACACAACAAATCATTGTTAAAA
GGTCTGGATTTGGCTGTTGAAACTATACAATCGAATCTAAAGCTAAATAAAATCTCAAGTGATAACTTACTTTCAATTTT
ACCTGAAATCGTAAAAGAATTTCAATTGGAGATGGAGGAAAAGGAAATCAAAGTGAACCTACCGGTTGTCAAACAAACGG
TTAACTTAGAACTAGATTTGAATTCATTGAAAACCATCCTACATGAAATTTTTACAAATGGATTAAAGTATTCAAAAACC
AAATCCAATTTTGATATTTTTGTCACATTTGTGGATGGGTATTTTTGTTTATCTGCGAAAAACAATATCATTGAAGATGA
TTATGCGAAACACCTTCTCCATTCTGAAAAAAAATTAGTGGAACCATTCTATCGAATACACCCACCTGTTGAAAGTTTTT
ATAAGAAAGAAAAATTTAGCCTTGGACTAGGATTAACAATGGTTGATTTTTTATTACACAAACATAACGGAATGTTTTTT
ATCAGAAATGCAATCGATCATACCACAGAAATCAAAGCATCGTGCGTGATCGCTGAAATTTTTCTCCCAATCCAAAATTA
A

Upstream 100 bases:

>100_bases
ATGGGGGGAAGGTTCCACATTTATACTCAAGATCCCTGAAAATATTAAATAAAGGTATTGAATGGATTAGAAATATCGAA
TAGAATTTCCGATATTCTAT

Downstream 100 bases:

>100_bases
AGGAAAACCAAATGAATAGAAAAATCTTAATTATCGATGACTCGGCAGTGTTTCGTAAAATCATTTCTGTCCATCTAAAA
AATGCAAACTTTGATCTCAT

Product: putative transcriptional regulatory protein ZraR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MVEPIEPTNPTVSKTEHLRRPKEPILIIEDKRENQVLLEGICKRIGATYEVAENGKIALEMAKMKSFSLYLVDLMMPIMD
GKTFITEQRKIEPRAVFIVQTAIDQTEEIIEIMKMGVYDYLIKPLHVEIVADRLEKTLEYVYLKRMEAVLIDEESKELKS
QLEWLNYKESHRKTNEVNAELNSILNLKTTLMQGSGIGAMTTIIDSIETIKKAENGNYLIPKEYWDIISENQEHNKSLLK
GLDLAVETIQSNLKLNKISSDNLLSILPEIVKEFQLEMEEKEIKVNLPVVKQTVNLELDLNSLKTILHEIFTNGLKYSKT
KSNFDIFVTFVDGYFCLSAKNNIIEDDYAKHLLHSEKKLVEPFYRIHPPVESFYKKEKFSLGLGLTMVDFLLHKHNGMFF
IRNAIDHTTEIKASCVIAEIFLPIQN

Sequences:

>Translated_426_residues
MVEPIEPTNPTVSKTEHLRRPKEPILIIEDKRENQVLLEGICKRIGATYEVAENGKIALEMAKMKSFSLYLVDLMMPIMD
GKTFITEQRKIEPRAVFIVQTAIDQTEEIIEIMKMGVYDYLIKPLHVEIVADRLEKTLEYVYLKRMEAVLIDEESKELKS
QLEWLNYKESHRKTNEVNAELNSILNLKTTLMQGSGIGAMTTIIDSIETIKKAENGNYLIPKEYWDIISENQEHNKSLLK
GLDLAVETIQSNLKLNKISSDNLLSILPEIVKEFQLEMEEKEIKVNLPVVKQTVNLELDLNSLKTILHEIFTNGLKYSKT
KSNFDIFVTFVDGYFCLSAKNNIIEDDYAKHLLHSEKKLVEPFYRIHPPVESFYKKEKFSLGLGLTMVDFLLHKHNGMFF
IRNAIDHTTEIKASCVIAEIFLPIQN
>Mature_426_residues
MVEPIEPTNPTVSKTEHLRRPKEPILIIEDKRENQVLLEGICKRIGATYEVAENGKIALEMAKMKSFSLYLVDLMMPIMD
GKTFITEQRKIEPRAVFIVQTAIDQTEEIIEIMKMGVYDYLIKPLHVEIVADRLEKTLEYVYLKRMEAVLIDEESKELKS
QLEWLNYKESHRKTNEVNAELNSILNLKTTLMQGSGIGAMTTIIDSIETIKKAENGNYLIPKEYWDIISENQEHNKSLLK
GLDLAVETIQSNLKLNKISSDNLLSILPEIVKEFQLEMEEKEIKVNLPVVKQTVNLELDLNSLKTILHEIFTNGLKYSKT
KSNFDIFVTFVDGYFCLSAKNNIIEDDYAKHLLHSEKKLVEPFYRIHPPVESFYKKEKFSLGLGLTMVDFLLHKHNGMFF
IRNAIDHTTEIKASCVIAEIFLPIQN

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=118, Percent_Identity=31.3559322033898, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 49141; Mature: 49141

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEPIEPTNPTVSKTEHLRRPKEPILIIEDKRENQVLLEGICKRIGATYEVAENGKIALE
CCCCCCCCCCCCHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEECCCCCEEEE
MAKMKSFSLYLVDLMMPIMDGKTFITEQRKIEPRAVFIVQTAIDQTEEIIEIMKMGVYDY
EHHHHHHHHHHHHHHHHHHCCCCEECHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHH
LIKPLHVEIVADRLEKTLEYVYLKRMEAVLIDEESKELKSQLEWLNYKESHRKTNEVNAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHCCCHHHHCHHHHHHHH
LNSILNLKTTLMQGSGIGAMTTIIDSIETIKKAENGNYLIPKEYWDIISENQEHNKSLLK
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHCCCCHHHHHHHH
GLDLAVETIQSNLKLNKISSDNLLSILPEIVKEFQLEMEEKEIKVNLPVVKQTVNLELDL
HHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEECCEEEEEEEEEEEH
NSLKTILHEIFTNGLKYSKTKSNFDIFVTFVDGYFCLSAKNNIIEDDYAKHLLHSEKKLV
HHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCEEEEECCCCCCCHHHHHHHHHHHHHHH
EPFYRIHPPVESFYKKEKFSLGLGLTMVDFLLHKHNGMFFIRNAIDHTTEIKASCVIAEI
HHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECHHCCCHHHHHHHEEEEH
FLPIQN
EEECCC
>Mature Secondary Structure
MVEPIEPTNPTVSKTEHLRRPKEPILIIEDKRENQVLLEGICKRIGATYEVAENGKIALE
CCCCCCCCCCCCHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEECCCCCEEEE
MAKMKSFSLYLVDLMMPIMDGKTFITEQRKIEPRAVFIVQTAIDQTEEIIEIMKMGVYDY
EHHHHHHHHHHHHHHHHHHCCCCEECHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHH
LIKPLHVEIVADRLEKTLEYVYLKRMEAVLIDEESKELKSQLEWLNYKESHRKTNEVNAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHCCCHHHHCHHHHHHHH
LNSILNLKTTLMQGSGIGAMTTIIDSIETIKKAENGNYLIPKEYWDIISENQEHNKSLLK
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHCCCCHHHHHHHH
GLDLAVETIQSNLKLNKISSDNLLSILPEIVKEFQLEMEEKEIKVNLPVVKQTVNLELDL
HHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEECCEEEEEEEEEEEH
NSLKTILHEIFTNGLKYSKTKSNFDIFVTFVDGYFCLSAKNNIIEDDYAKHLLHSEKKLV
HHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCEEEEECCCCCCCHHHHHHHHHHHHHHH
EPFYRIHPPVESFYKKEKFSLGLGLTMVDFLLHKHNGMFFIRNAIDHTTEIKASCVIAEI
HHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECHHCCCHHHHHHHEEEEH
FLPIQN
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]