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The map label for this gene is glpD [H]

Identifier: 183220956

GI number: 183220956

Start: 1636932

End: 1638539

Strand: Reverse

Name: glpD [H]

Synonym: LEPBI_I1569

Alternate gene names: 183220956

Gene position: 1638539-1636932 (Counterclockwise)

Preceding gene: 183220959

Following gene: 183220949

Centisome position: 45.52

GC content: 42.79

Gene sequence:

>1608_bases
ATGAACCATTTAGATGAAAGAAAACAAACACTGAAACAGTTAGAATCTACCCAATATGATATTTTGATTTTGGGTGGTGG
TGCCACAGGTTCCGGCACGGCCCTCGATGCGAGCCTACGCGGGTACAAAGTAGCCCTTCTCGAAAAAGCGGACTTCTCGC
AAGGGACTAGTTCACGTTCCACAAAACTCATCCATGGTGGGGTTCGTTACCTTGCCCAGTTCCATTTCAAATTGATTTAT
GAAGCTTTATCCGAAAGAAAGCGCCTTCTCATCAATGCTCCCCACCTCGTCAAACCTCTCCAATTTGTACTACCTACCTA
TGTTTGGTGGGAAAAACCATTTTATTCCATTGGTCTCACGATGTATGACCTACTCGCAGGAAAGTCCATCGTCCCTGGCC
ATGAAAGAATCTCGAAAGCAACTGCCCTTGATTATTTTGCCTCTTTAAAAAAACAAAACCTAAAGGGTGGGATATCCTAT
TATGATGCCCAGTTCAATGACGCAAGGCTCAATGTAACAACCGTTCGTGCCGCAAAAGAAAATGGTGCGGATGTGGTCTC
GAGGATCGAAGTGACAAACTTTTTAAAAGATGCCAACGGTAAGATCATTGGTGTGACGGCTAAAGATGCCATCACCAAAA
AAGTAGTTTCCATCAAAGCCAAAGTAGTCGCAAACACAACGGGGGTTTGGATTGATTCCCTACGCAAATTGGATGATCCC
AAAGCAGAAAATGTCCTTGCTCCAAGCCAAGGCATCCACTTAGTCTTTGACAAAGAAAAATTACCATGCCGCACGGCGAT
GATCATTCCCAAAACGGCTGATGGCCGAGTGGTGTTTGTCATCCCTTGGGAAGGAAAAGTATTACTGGGAACTACCGATA
CTCCCATCCAAAAAATCGATGATGAACCCCTTCCCTTACAATCGGAAGTGGAATTTTTGTTAAAAACTGGAAATGAATAT
TTGGATACCAAATTAACCAAAGCAGACATCGAATCTGTGTTTAGCGGGTTACGACCACTCATCTCGACAGGTGACAAAAA
AGATACAAAATCCATCTCAAGAGAAGAAGCCATCCTTGTCTCCGACTCAGGACTTGTGACGATGTCTGGTGGGAAATGGT
CTACATTTCGGAAGATGGCAGAAGACCTAACCGACAAATTGATCTCTGTTGGTAACCTAACTTCTAAAATGAAATGTTTT
ACGGCAAGTTTTGCCTTCCCGGGAGCTGACGGTTATAGCAAACACTTAGTAGCCAAAATCCAAACTATGTATGACCTCCC
ATATGAAACAGCGGTTCGTTTGAGCGATGCTTATGGCGGAGAAGTTCCACTCATCCTTGGCAAAAAACCAAAGGAAATCA
AAAAAGGCAGTGGTTACTTTGCAGAAGAGATCAAACATTTTGTGAAAAAGGAATTTGCACTTTCCCTTTCCGATGTAATG
GCGAGACGGTGGAGGATCCTCTTTTTGGATTTAAACTTAGCAGAATCACTTGCAATGCAAACAAACAACATCCTTGCCAA
AGAACTTGGCTGGAAGGAAACAGAGAAAAAATCGTCTCTAAACGAACTTCTAAAACACATTAAGGATTTAAAGAAAACAA
TCGCTTAA

Upstream 100 bases:

>100_bases
CATAACAATTTCAAAAATTTTCGATGGTAGAAAAGGTGACTTTTGACAACACTAACCTTAGAATCTCTATAGGCAACCAC
CAAAGTACGTAAAAACCCTT

Downstream 100 bases:

>100_bases
CGTTGATTCTGCGAAAAATGCAAGGTGTAGATATTTTTTATTCTGCACCAAACCTATTTCGGAATTGCTAGTTCGTAATG
GTAAAATGTCCGACCCGTTT

Product: aerobic glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 535; Mature: 535

Protein sequence:

>535_residues
MNHLDERKQTLKQLESTQYDILILGGGATGSGTALDASLRGYKVALLEKADFSQGTSSRSTKLIHGGVRYLAQFHFKLIY
EALSERKRLLINAPHLVKPLQFVLPTYVWWEKPFYSIGLTMYDLLAGKSIVPGHERISKATALDYFASLKKQNLKGGISY
YDAQFNDARLNVTTVRAAKENGADVVSRIEVTNFLKDANGKIIGVTAKDAITKKVVSIKAKVVANTTGVWIDSLRKLDDP
KAENVLAPSQGIHLVFDKEKLPCRTAMIIPKTADGRVVFVIPWEGKVLLGTTDTPIQKIDDEPLPLQSEVEFLLKTGNEY
LDTKLTKADIESVFSGLRPLISTGDKKDTKSISREEAILVSDSGLVTMSGGKWSTFRKMAEDLTDKLISVGNLTSKMKCF
TASFAFPGADGYSKHLVAKIQTMYDLPYETAVRLSDAYGGEVPLILGKKPKEIKKGSGYFAEEIKHFVKKEFALSLSDVM
ARRWRILFLDLNLAESLAMQTNNILAKELGWKETEKKSSLNELLKHIKDLKKTIA

Sequences:

>Translated_535_residues
MNHLDERKQTLKQLESTQYDILILGGGATGSGTALDASLRGYKVALLEKADFSQGTSSRSTKLIHGGVRYLAQFHFKLIY
EALSERKRLLINAPHLVKPLQFVLPTYVWWEKPFYSIGLTMYDLLAGKSIVPGHERISKATALDYFASLKKQNLKGGISY
YDAQFNDARLNVTTVRAAKENGADVVSRIEVTNFLKDANGKIIGVTAKDAITKKVVSIKAKVVANTTGVWIDSLRKLDDP
KAENVLAPSQGIHLVFDKEKLPCRTAMIIPKTADGRVVFVIPWEGKVLLGTTDTPIQKIDDEPLPLQSEVEFLLKTGNEY
LDTKLTKADIESVFSGLRPLISTGDKKDTKSISREEAILVSDSGLVTMSGGKWSTFRKMAEDLTDKLISVGNLTSKMKCF
TASFAFPGADGYSKHLVAKIQTMYDLPYETAVRLSDAYGGEVPLILGKKPKEIKKGSGYFAEEIKHFVKKEFALSLSDVM
ARRWRILFLDLNLAESLAMQTNNILAKELGWKETEKKSSLNELLKHIKDLKKTIA
>Mature_535_residues
MNHLDERKQTLKQLESTQYDILILGGGATGSGTALDASLRGYKVALLEKADFSQGTSSRSTKLIHGGVRYLAQFHFKLIY
EALSERKRLLINAPHLVKPLQFVLPTYVWWEKPFYSIGLTMYDLLAGKSIVPGHERISKATALDYFASLKKQNLKGGISY
YDAQFNDARLNVTTVRAAKENGADVVSRIEVTNFLKDANGKIIGVTAKDAITKKVVSIKAKVVANTTGVWIDSLRKLDDP
KAENVLAPSQGIHLVFDKEKLPCRTAMIIPKTADGRVVFVIPWEGKVLLGTTDTPIQKIDDEPLPLQSEVEFLLKTGNEY
LDTKLTKADIESVFSGLRPLISTGDKKDTKSISREEAILVSDSGLVTMSGGKWSTFRKMAEDLTDKLISVGNLTSKMKCF
TASFAFPGADGYSKHLVAKIQTMYDLPYETAVRLSDAYGGEVPLILGKKPKEIKKGSGYFAEEIKHFVKKEFALSLSDVM
ARRWRILFLDLNLAESLAMQTNNILAKELGWKETEKKSSLNELLKHIKDLKKTIA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=536, Percent_Identity=37.5, Blast_Score=375, Evalue=1e-104,
Organism=Homo sapiens, GI285002231, Length=536, Percent_Identity=37.5, Blast_Score=375, Evalue=1e-104,
Organism=Escherichia coli, GI2367226, Length=465, Percent_Identity=31.1827956989247, Blast_Score=181, Evalue=2e-46,
Organism=Escherichia coli, GI1788574, Length=390, Percent_Identity=27.9487179487179, Blast_Score=124, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17509253, Length=538, Percent_Identity=38.6617100371747, Blast_Score=362, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI115534726, Length=546, Percent_Identity=34.2490842490842, Blast_Score=326, Evalue=2e-89,
Organism=Saccharomyces cerevisiae, GI6322036, Length=594, Percent_Identity=33.6700336700337, Blast_Score=323, Evalue=4e-89,
Organism=Drosophila melanogaster, GI161077125, Length=542, Percent_Identity=38.1918819188192, Blast_Score=361, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24653942, Length=542, Percent_Identity=38.1918819188192, Blast_Score=361, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24653944, Length=542, Percent_Identity=38.1918819188192, Blast_Score=361, Evalue=1e-100,
Organism=Drosophila melanogaster, GI20130025, Length=542, Percent_Identity=38.1918819188192, Blast_Score=361, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24586295, Length=543, Percent_Identity=32.9650092081031, Blast_Score=298, Evalue=7e-81,
Organism=Drosophila melanogaster, GI19921278, Length=542, Percent_Identity=29.520295202952, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI45550977, Length=390, Percent_Identity=27.4358974358974, Blast_Score=159, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 59386; Mature: 59386

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHLDERKQTLKQLESTQYDILILGGGATGSGTALDASLRGYKVALLEKADFSQGTSSRS
CCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCCC
TKLIHGGVRYLAQFHFKLIYEALSERKRLLINAPHLVKPLQFVLPTYVWWEKPFYSIGLT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHH
MYDLLAGKSIVPGHERISKATALDYFASLKKQNLKGGISYYDAQFNDARLNVTTVRAAKE
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEEEECCC
NGADVVSRIEVTNFLKDANGKIIGVTAKDAITKKVVSIKAKVVANTTGVWIDSLRKLDDP
CCHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHEEEEECCCHHHHHHHHHCCCC
KAENVLAPSQGIHLVFDKEKLPCRTAMIIPKTADGRVVFVIPWEGKVLLGTTDTPIQKID
CCCCCCCCCCCEEEEECCCCCCEEEEEEEEECCCCEEEEEEECCCEEEEECCCCCHHHCC
DEPLPLQSEVEFLLKTGNEYLDTKLTKADIESVFSGLRPLISTGDKKDTKSISREEAILV
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEE
SDSGLVTMSGGKWSTFRKMAEDLTDKLISVGNLTSKMKCFTASFAFPGADGYSKHLVAKI
ECCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHEEEECCCCCCCCHHHHHHHHH
QTMYDLPYETAVRLSDAYGGEVPLILGKKPKEIKKGSGYFAEEIKHFVKKEFALSLSDVM
HHHHCCCHHHHHEEHHCCCCCEEEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ARRWRILFLDLNLAESLAMQTNNILAKELGWKETEKKSSLNELLKHIKDLKKTIA
HHCEEEEEEECCHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNHLDERKQTLKQLESTQYDILILGGGATGSGTALDASLRGYKVALLEKADFSQGTSSRS
CCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCCC
TKLIHGGVRYLAQFHFKLIYEALSERKRLLINAPHLVKPLQFVLPTYVWWEKPFYSIGLT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHH
MYDLLAGKSIVPGHERISKATALDYFASLKKQNLKGGISYYDAQFNDARLNVTTVRAAKE
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEEEECCC
NGADVVSRIEVTNFLKDANGKIIGVTAKDAITKKVVSIKAKVVANTTGVWIDSLRKLDDP
CCHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHEEEEECCCHHHHHHHHHCCCC
KAENVLAPSQGIHLVFDKEKLPCRTAMIIPKTADGRVVFVIPWEGKVLLGTTDTPIQKID
CCCCCCCCCCCEEEEECCCCCCEEEEEEEEECCCCEEEEEEECCCEEEEECCCCCHHHCC
DEPLPLQSEVEFLLKTGNEYLDTKLTKADIESVFSGLRPLISTGDKKDTKSISREEAILV
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEE
SDSGLVTMSGGKWSTFRKMAEDLTDKLISVGNLTSKMKCFTASFAFPGADGYSKHLVAKI
ECCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHEEEECCCCCCCCHHHHHHHHH
QTMYDLPYETAVRLSDAYGGEVPLILGKKPKEIKKGSGYFAEEIKHFVKKEFALSLSDVM
HHHHCCCHHHHHEEHHCCCCCEEEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ARRWRILFLDLNLAESLAMQTNNILAKELGWKETEKKSSLNELLKHIKDLKKTIA
HHCEEEEEEECCHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]