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The map label for this gene is fbp [H]

Identifier: 183220949

GI number: 183220949

Start: 1629292

End: 1630443

Strand: Reverse

Name: fbp [H]

Synonym: LEPBI_I1562

Alternate gene names: 183220949

Gene position: 1630443-1629292 (Counterclockwise)

Preceding gene: 183220956

Following gene: 183220948

Centisome position: 45.29

GC content: 44.88

Gene sequence:

>1152_bases
TTGGTTCTGTCATGGCTCTTACGTGATAGTATCGGTTTTTGCCCTTCGTTTCAAAAGGAGAAAGGATTTGCTCCCTACCC
ACAACCACAAAAATGGAGTAAAAACAACCTCGGGGATACTGTGAACGCAACACCGAAACAAAAAAAACTCATCTCTCTAT
CGCAATTCATCCTAGAAGAGCAACTCAAAATCCCTCATGCATCTGGAGAATTTTCTGCCCTTCTCAGCCATTTGGTTTAT
GCCGCAAAAATTGTTGGTCGGGAAGTGAGAAAAGCGGGCCTTTTGGATGACATCCTCGGAGCCACAGAAGACACGAATGT
CCAAGGGGAAACCCAAATGAAATTGGACCAATACGCCGATAACGCTTTCAACCAATCCTTAAAAATTTGTGGCCATCTCT
GTGTCCTTGCCAGCGAAGAACACGAAGACATCATCCCCATTCCTGGTGGTTACAATATTGGTAAGTACACGATGGCGATC
GATCCCTTGGACGGATCCTCCAATATTGACACCAATGTTTCCATCGGGACCATTTTCTCCATCCACCAACGTTTGGAACC
AAACTCTAAAGAACCAGGAAATGAACGTGACCTCCTCCAAAAAGGGCATTTGCAACGATGTGCAGGGTACATCATTTATG
GTTCCTCAACCATGCTCGTTTTATCGACAGGAAAGGGAGTTTCAGGTTTTACCCTCGATCCAAGTGTGGGTGAATTTTTA
CTCTCTCATCCCAATATGCAAATGCCAGAATCAGGCGATATTTACTCCGCCAATGAAGGGAATGCCTCCTATTGGTCCCC
GGAAGTACAAGCCTACCTCCAAAAAATCAAATCCATAGAAGGAGGGAAAAAACCAAAAACAGCTCGTTACATCGGTTCTC
TTGTCGCGGACTTCCATCGGAACCTACTCAAAGGGGGGATTTTCCTCTATCCAAATGACACCAAATCAAGCAAATACCCG
AATGGAAAACTAAGGTTATTGTATGAAGCAGCTCCCATGGCCTTCATTGCGGAACAAGCGGGTGGGATGGCAGTCACTGT
CAAAGGAGAACGCATCTTGGACCTAACACCGAAAGACCTCCATGAACGAACAACGCTCATCATTGGAAGTAAAAAAGAAG
TAGAGGAATTTCTGACATTTGTTGCGAAATAA

Upstream 100 bases:

>100_bases
AACACCCATCCCAATCGAGCTCCGACACTCGCAAAACTGAGTCCCAAACGTCGGGAATGGTAATCTGTCATTTGCATGGA
AGGAGAAGGACTGAGGTGCA

Downstream 100 bases:

>100_bases
CCGTCACAGATTTTTCGCTTTTGCTACAGAAATTTCTTTCAATAGAAACTGAGTTCGGTTAGATTTGGCAGAATTAAAAG
ATTTTTTTAGGAGAAAACTT

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MVLSWLLRDSIGFCPSFQKEKGFAPYPQPQKWSKNNLGDTVNATPKQKKLISLSQFILEEQLKIPHASGEFSALLSHLVY
AAKIVGREVRKAGLLDDILGATEDTNVQGETQMKLDQYADNAFNQSLKICGHLCVLASEEHEDIIPIPGGYNIGKYTMAI
DPLDGSSNIDTNVSIGTIFSIHQRLEPNSKEPGNERDLLQKGHLQRCAGYIIYGSSTMLVLSTGKGVSGFTLDPSVGEFL
LSHPNMQMPESGDIYSANEGNASYWSPEVQAYLQKIKSIEGGKKPKTARYIGSLVADFHRNLLKGGIFLYPNDTKSSKYP
NGKLRLLYEAAPMAFIAEQAGGMAVTVKGERILDLTPKDLHERTTLIIGSKKEVEEFLTFVAK

Sequences:

>Translated_383_residues
MVLSWLLRDSIGFCPSFQKEKGFAPYPQPQKWSKNNLGDTVNATPKQKKLISLSQFILEEQLKIPHASGEFSALLSHLVY
AAKIVGREVRKAGLLDDILGATEDTNVQGETQMKLDQYADNAFNQSLKICGHLCVLASEEHEDIIPIPGGYNIGKYTMAI
DPLDGSSNIDTNVSIGTIFSIHQRLEPNSKEPGNERDLLQKGHLQRCAGYIIYGSSTMLVLSTGKGVSGFTLDPSVGEFL
LSHPNMQMPESGDIYSANEGNASYWSPEVQAYLQKIKSIEGGKKPKTARYIGSLVADFHRNLLKGGIFLYPNDTKSSKYP
NGKLRLLYEAAPMAFIAEQAGGMAVTVKGERILDLTPKDLHERTTLIIGSKKEVEEFLTFVAK
>Mature_383_residues
MVLSWLLRDSIGFCPSFQKEKGFAPYPQPQKWSKNNLGDTVNATPKQKKLISLSQFILEEQLKIPHASGEFSALLSHLVY
AAKIVGREVRKAGLLDDILGATEDTNVQGETQMKLDQYADNAFNQSLKICGHLCVLASEEHEDIIPIPGGYNIGKYTMAI
DPLDGSSNIDTNVSIGTIFSIHQRLEPNSKEPGNERDLLQKGHLQRCAGYIIYGSSTMLVLSTGKGVSGFTLDPSVGEFL
LSHPNMQMPESGDIYSANEGNASYWSPEVQAYLQKIKSIEGGKKPKTARYIGSLVADFHRNLLKGGIFLYPNDTKSSKYP
NGKLRLLYEAAPMAFIAEQAGGMAVTVKGERILDLTPKDLHERTTLIIGSKKEVEEFLTFVAK

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI22907028, Length=342, Percent_Identity=43.2748538011696, Blast_Score=260, Evalue=1e-69,
Organism=Homo sapiens, GI189083692, Length=342, Percent_Identity=45.0292397660819, Blast_Score=257, Evalue=1e-68,
Organism=Homo sapiens, GI16579888, Length=342, Percent_Identity=45.0292397660819, Blast_Score=257, Evalue=1e-68,
Organism=Escherichia coli, GI1790679, Length=331, Percent_Identity=50.4531722054381, Blast_Score=311, Evalue=5e-86,
Organism=Caenorhabditis elegans, GI17508131, Length=333, Percent_Identity=49.8498498498498, Blast_Score=306, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6323409, Length=336, Percent_Identity=46.7261904761905, Blast_Score=302, Evalue=5e-83,
Organism=Drosophila melanogaster, GI19921562, Length=331, Percent_Identity=47.1299093655589, Blast_Score=263, Evalue=1e-70,
Organism=Drosophila melanogaster, GI45550998, Length=331, Percent_Identity=47.1299093655589, Blast_Score=263, Evalue=1e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146
- InterPro:   IPR020548 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 42158; Mature: 42158

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS00124 FBPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLSWLLRDSIGFCPSFQKEKGFAPYPQPQKWSKNNLGDTVNATPKQKKLISLSQFILEE
CHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
QLKIPHASGEFSALLSHLVYAAKIVGREVRKAGLLDDILGATEDTNVQGETQMKLDQYAD
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHH
NAFNQSLKICGHLCVLASEEHEDIIPIPGGYNIGKYTMAIDPLDGSSNIDTNVSIGTIFS
HHHHHHHHHHHHHHEEECCCCCCEEECCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHH
IHQRLEPNSKEPGNERDLLQKGHLQRCAGYIIYGSSTMLVLSTGKGVSGFTLDPSVGEFL
HHHHCCCCCCCCCCHHHHHHHCCHHHHCCEEEECCCEEEEEECCCCCCCEEECCHHHHHH
LSHPNMQMPESGDIYSANEGNASYWSPEVQAYLQKIKSIEGGKKPKTARYIGSLVADFHR
HCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
NLLKGGIFLYPNDTKSSKYPNGKLRLLYEAAPMAFIAEQAGGMAVTVKGERILDLTPKDL
HHHHCCEEEEECCCCCCCCCCCCEEEEEECCCHHHHHHCCCCEEEEEECCEEEECCCHHH
HERTTLIIGSKKEVEEFLTFVAK
HCCEEEEECCHHHHHHHHHHHCC
>Mature Secondary Structure
MVLSWLLRDSIGFCPSFQKEKGFAPYPQPQKWSKNNLGDTVNATPKQKKLISLSQFILEE
CHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
QLKIPHASGEFSALLSHLVYAAKIVGREVRKAGLLDDILGATEDTNVQGETQMKLDQYAD
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHH
NAFNQSLKICGHLCVLASEEHEDIIPIPGGYNIGKYTMAIDPLDGSSNIDTNVSIGTIFS
HHHHHHHHHHHHHHEEECCCCCCEEECCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHH
IHQRLEPNSKEPGNERDLLQKGHLQRCAGYIIYGSSTMLVLSTGKGVSGFTLDPSVGEFL
HHHHCCCCCCCCCCHHHHHHHCCHHHHCCEEEECCCEEEEEECCCCCCCEEECCHHHHHH
LSHPNMQMPESGDIYSANEGNASYWSPEVQAYLQKIKSIEGGKKPKTARYIGSLVADFHR
HCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
NLLKGGIFLYPNDTKSSKYPNGKLRLLYEAAPMAFIAEQAGGMAVTVKGERILDLTPKDL
HHHHCCEEEEECCCCCCCCCCCCEEEEEECCCHHHHHHCCCCEEEEEECCEEEECCCHHH
HERTTLIIGSKKEVEEFLTFVAK
HCCEEEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA