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The map label for this gene is pqqL [C]

Identifier: 183220917

GI number: 183220917

Start: 1596329

End: 1597615

Strand: Direct

Name: pqqL [C]

Synonym: LEPBI_I1530

Alternate gene names: 183220917

Gene position: 1596329-1597615 (Clockwise)

Preceding gene: 183220916

Following gene: 183220918

Centisome position: 44.35

GC content: 40.09

Gene sequence:

>1287_bases
ATGGTTTCCGTCAGTGAATGCAAACGAACTGTTTTACCAAATGGTTTGACAGTCCTTTTCCAACCAATGAAACACGCATC
CTCTATGGGGGTGGGTGTTTTTTTGAAACAAGGCAGTCTTGCCGAATCCAATTCCGAACATGGTTATTTTCACTTTTTAG
AGCACATGCTCTTCAAAGATACGGAAACTCGTACAAGTAAGGAAATTGCCGAATCCATTGAGCGCGTGGGTGGGATCTTA
AATGGATCTACTGGTCGGGAATACACACAATACTACGTCGTTGCCATCAAAAACCAAGCAGAACTTGCGTTTGAAATTTT
ATCCGATATGCTCTTTCGGCCACTCTTTCGCAAAGAAGACATCCAAACAGAAAAGGGTGTCATCATGGAAGAGATGCGTT
CTTACGAGGATGCCCCTGATGATTTTGTTTATGATTATTACTTTCGTAATATATTTGGGAAATCACCTTACGGGCGTGAT
ATCATTGGAACAAAAACATCAGTCACTGGTGTCACGGAATCCTCCATTCGTAGGTTTTTTGAAAAACATTATTTCCCGAA
AAATATGGTCATCTCTGTATCTGGAAATTTTACTTGGGAAAAGGTTTTGGATCTTACCAAAAAATACTTTTCTTTTGCAA
ATCCAAAAGGAAAAAACCCAACGGAACTTTTGATCCCATCACCTAAAAAAAGTTATACGAAACATTTGGAGCGCCGTAAA
ATCGAACAGTTCCATATCATGCTTGGTGTCAATGGAAGTAAAAGGGACTATCGAACGGTAACTGTGGCAGGCCTTATCTC
CACCATTCTTGGAGGGGGAATGGCCTCACGGCTTTTCCAAAATATCCGGGAAAAAGAAGGACTTTGTTATAGCATTTATA
GTTTTCCATCTTATTACAAAACCACTGGTTTATTTTCGATCTCTTCTGCCACTTCCAAAGAAAAAGCGGCACGTTGTGTG
GAACTCATCCTAAAGGAATTGGAAACCATTACCAAACATGGTTTTTCCAAAAAAGAACTCGCTGATGCGAAATCCAATCA
AATGGGTTCGATTGCCATCGGGTATGAACTGCCTGAAAACCGAATGAATAATATTGGCCTCCAAGAAATTTATTATGGTA
AATATTTTTCCTTGGAAGATCGGATGAGGGCAATCAAGTCAGTGACTTTGGAGGAAATCAATCATGTCGCCAAAGAGATG
TTTGGTTTAGAAAAAGTCCATTTGTCTTGTGTAGGAGATATGACAGAAAGCCAATTTGCCAAAATCCCGGTCCAATTTGG
CGGTTGA

Upstream 100 bases:

>100_bases
ATTTCCGTTGATAAAATGGGAAAAATTGATCTTTCACGAAAGGATGTCCTTTTAGACAACTAAACAGTCCCCAAACACCT
GTTTGGGGGGAGTGAAACAA

Downstream 100 bases:

>100_bases
GAAGGAAATATCGATTCGGCTTTAGCTCGTATGAATCGCATGTTAAGGAATTTATGTTAGAACCCGAGAACTACCTCCAA
ATCCAAATCTTAAAAGAGGG

Product: putative zinc-dependent peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MVSVSECKRTVLPNGLTVLFQPMKHASSMGVGVFLKQGSLAESNSEHGYFHFLEHMLFKDTETRTSKEIAESIERVGGIL
NGSTGREYTQYYVVAIKNQAELAFEILSDMLFRPLFRKEDIQTEKGVIMEEMRSYEDAPDDFVYDYYFRNIFGKSPYGRD
IIGTKTSVTGVTESSIRRFFEKHYFPKNMVISVSGNFTWEKVLDLTKKYFSFANPKGKNPTELLIPSPKKSYTKHLERRK
IEQFHIMLGVNGSKRDYRTVTVAGLISTILGGGMASRLFQNIREKEGLCYSIYSFPSYYKTTGLFSISSATSKEKAARCV
ELILKELETITKHGFSKKELADAKSNQMGSIAIGYELPENRMNNIGLQEIYYGKYFSLEDRMRAIKSVTLEEINHVAKEM
FGLEKVHLSCVGDMTESQFAKIPVQFGG

Sequences:

>Translated_428_residues
MVSVSECKRTVLPNGLTVLFQPMKHASSMGVGVFLKQGSLAESNSEHGYFHFLEHMLFKDTETRTSKEIAESIERVGGIL
NGSTGREYTQYYVVAIKNQAELAFEILSDMLFRPLFRKEDIQTEKGVIMEEMRSYEDAPDDFVYDYYFRNIFGKSPYGRD
IIGTKTSVTGVTESSIRRFFEKHYFPKNMVISVSGNFTWEKVLDLTKKYFSFANPKGKNPTELLIPSPKKSYTKHLERRK
IEQFHIMLGVNGSKRDYRTVTVAGLISTILGGGMASRLFQNIREKEGLCYSIYSFPSYYKTTGLFSISSATSKEKAARCV
ELILKELETITKHGFSKKELADAKSNQMGSIAIGYELPENRMNNIGLQEIYYGKYFSLEDRMRAIKSVTLEEINHVAKEM
FGLEKVHLSCVGDMTESQFAKIPVQFGG
>Mature_428_residues
MVSVSECKRTVLPNGLTVLFQPMKHASSMGVGVFLKQGSLAESNSEHGYFHFLEHMLFKDTETRTSKEIAESIERVGGIL
NGSTGREYTQYYVVAIKNQAELAFEILSDMLFRPLFRKEDIQTEKGVIMEEMRSYEDAPDDFVYDYYFRNIFGKSPYGRD
IIGTKTSVTGVTESSIRRFFEKHYFPKNMVISVSGNFTWEKVLDLTKKYFSFANPKGKNPTELLIPSPKKSYTKHLERRK
IEQFHIMLGVNGSKRDYRTVTVAGLISTILGGGMASRLFQNIREKEGLCYSIYSFPSYYKTTGLFSISSATSKEKAARCV
ELILKELETITKHGFSKKELADAKSNQMGSIAIGYELPENRMNNIGLQEIYYGKYFSLEDRMRAIKSVTLEEINHVAKEM
FGLEKVHLSCVGDMTESQFAKIPVQFGG

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=407, Percent_Identity=26.2899262899263, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI46593007, Length=317, Percent_Identity=26.4984227129338, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI24308013, Length=441, Percent_Identity=23.8095238095238, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1787770, Length=373, Percent_Identity=27.6139410187668, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71999683, Length=423, Percent_Identity=25.2955082742317, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17553678, Length=322, Percent_Identity=25.4658385093168, Blast_Score=99, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6323192, Length=419, Percent_Identity=27.6849642004773, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6321813, Length=419, Percent_Identity=21.9570405727924, Blast_Score=90, Evalue=7e-19,
Organism=Drosophila melanogaster, GI21357875, Length=319, Percent_Identity=27.5862068965517, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24646943, Length=319, Percent_Identity=27.5862068965517, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI19921772, Length=427, Percent_Identity=22.0140515222482, Blast_Score=83, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 48669; Mature: 48669

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSVSECKRTVLPNGLTVLFQPMKHASSMGVGVFLKQGSLAESNSEHGYFHFLEHMLFKD
CCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCC
TETRTSKEIAESIERVGGILNGSTGREYTQYYVVAIKNQAELAFEILSDMLFRPLFRKED
CCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHC
IQTEKGVIMEEMRSYEDAPDDFVYDYYFRNIFGKSPYGRDIIGTKTSVTGVTESSIRRFF
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
EKHYFPKNMVISVSGNFTWEKVLDLTKKYFSFANPKGKNPTELLIPSPKKSYTKHLERRK
HHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHH
IEQFHIMLGVNGSKRDYRTVTVAGLISTILGGGMASRLFQNIREKEGLCYSIYSFPSYYK
HHHEEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEHHCCCHHH
TTGLFSISSATSKEKAARCVELILKELETITKHGFSKKELADAKSNQMGSIAIGYELPEN
HCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEEEEECCHH
RMNNIGLQEIYYGKYFSLEDRMRAIKSVTLEEINHVAKEMFGLEKVHLSCVGDMTESQFA
HHHCCCHHHHHCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
KIPVQFGG
CCCEECCC
>Mature Secondary Structure
MVSVSECKRTVLPNGLTVLFQPMKHASSMGVGVFLKQGSLAESNSEHGYFHFLEHMLFKD
CCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCC
TETRTSKEIAESIERVGGILNGSTGREYTQYYVVAIKNQAELAFEILSDMLFRPLFRKED
CCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHC
IQTEKGVIMEEMRSYEDAPDDFVYDYYFRNIFGKSPYGRDIIGTKTSVTGVTESSIRRFF
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
EKHYFPKNMVISVSGNFTWEKVLDLTKKYFSFANPKGKNPTELLIPSPKKSYTKHLERRK
HHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHH
IEQFHIMLGVNGSKRDYRTVTVAGLISTILGGGMASRLFQNIREKEGLCYSIYSFPSYYK
HHHEEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEHHCCCHHH
TTGLFSISSATSKEKAARCVELILKELETITKHGFSKKELADAKSNQMGSIAIGYELPEN
HCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEEEEECCHH
RMNNIGLQEIYYGKYFSLEDRMRAIKSVTLEEINHVAKEMFGLEKVHLSCVGDMTESQFA
HHHCCCHHHHHCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
KIPVQFGG
CCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]