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The map label for this gene is ychK [C]

Identifier: 183220889

GI number: 183220889

Start: 1561888

End: 1563762

Strand: Direct

Name: ychK [C]

Synonym: LEPBI_I1502

Alternate gene names: 183220889

Gene position: 1561888-1563762 (Clockwise)

Preceding gene: 183220887

Following gene: 183220890

Centisome position: 43.39

GC content: 40.91

Gene sequence:

>1875_bases
GTGAAACGAATCCGAAAATCGAAAAACCCAAGCCTAGCCCAGTATTTGACATTGGCGGATTTGTTTCAAAATTTGCCTCA
CTCAGTCTTACGAGAGATGATGGATCATACTGTCCGTGAATTTCTAAAAGGGGGGGAGATCCTTTTTTTAGAAAACTCCA
TCGGTAGTGATTTGTACATTTTGGCTGCCGGGAAACTTCGGTATGAAAAACGAGGGCCAAATGGTGCTTTACGTGATATT
GGTGAATTCAAACGTCTCGATGTCATAGGTGAGCTCAGTTTGTTCACAGGAGAAAAACGATCTGCCACAGTGAAAGCGGT
GCGTGATTCCGAACTGATCCGAGTGCCAAGAGAAGTAGCTCTTTCGATTTTACTCAAATACCCTGATAGTTTATTACAAA
TCACAAAAATCATCGCCGAACGACTGGCTCATGCCAAAACAGAAACAAAAAGTTTTCTACCTCAAGCCAAAACATTTTCT
TTGCTTTCTTCCTTACCCGAAAAAACAATTTTGGATGCCATTCATTACCTTGGGATTGTATTTTTGCGGTATGGATCTAT
TTACGTTGTCGACGAATCCATGTTTAACGAAAAGACTCGGGAATTGGAAAAATTAGACGAGGTCGACCGAAAACCTTGGA
TCATCCGGTTTTTCACTCAAATCGAAGCTGAGTATGATTATATTTTTTATCTACTCAAGGATGAGGACAAGGTGAGTCCT
TTTGCAGAACGAGCCCTACGCCAATCGGATAGTTTTGTCTACATTAAAGATGCAAACGAATCTCCAAGTTGTATCCAATT
GGAAACTCTTATCGACAAACGCAAGTACAACGATCGTAACCATATACTTGTTCTCATCCAACCAAATAAGGATGAGGTAA
AACCAGGAACCATCAAACATTTACAAAAACGAAAATTCCATCGGCATTTCCATGTCCATATGGAGCGAATGGACACTTGG
GAACGACTTGGTAGAGGGTTACTTGGGAAATCCATTGGACTGGCGTTAGGTGGTGGAGGAGCAAAAGGTTTTGCCCATTT
AGGGGTGCTCCGAGCACTCGAAGAAAATAACATCCCAATCGATATGGTTTCCGGTACCAGTGCAGGTTCGATTTTTGCTG
CTCTCATTGCCATGGGTGAATCGAGTCTTAGCAGTAAAACAAAGGCGAAAGAATTTTGGGTAAACAAAGATCTTCTAAAC
GAATACACACTCCCAATCTTATCTCTCACCACTGGGAAAAAGTATACTGAAGCAATCCGACAATTTTTTGGTGAGATCCA
AATTGAAGACCTTTGGATTCCTTATTTTCCTGTCGCAACCAATTTATCTCATTCTGAAATCCATGTGCAGGAAGTTGGGA
GCTTATGGAAGGCCATTCGGGCGAGTACCTCCATTCCTGGGATTGTGCCACCGTTTATCGATGATGGGATTGTGTATGTT
GATGGAGGAGTCCTTGACAATGTGCCTGGGATTAGTTTGAAAGAACGAGGTGTGGGAAAAGTGATTTCTGTCGATGTGTT
TGGTGATATATACCCAGACCAAGACCGCGAACTTTGTGAATACTTTGATAGTAAAAATCCTGGTGTGATGACAAATCCAT
TCTTTCAAATGACAAACCTAATCAATTTCCAAGATTTGACAAAACCCAAATTCCCACCGATTGGTGATATCATCATCCGT
TCAATCCTCGCCTCCAGTCGGGAACGAATCCGCCAAACGGAAACAATATCAGATTTGTTTTTACAAATCCCGACCAATAA
TTTTGGATTATTAGATTGGTTTGCTTATGAACGTTTGATTGAACTTGGTTACATTTCTTCGGTTGGAAAAATCAAAATGA
ACCGCGAGAAATTTATAAATCCTTCTTTACAATAA

Upstream 100 bases:

>100_bases
TCAAATATGACTACTCTTCTTTTTTCATTGGATCAAATCACAATCCGATCGAACAAAAAGGTTGCTTGAAATTTTTTGAA
AGATCGCTACAACCTTTGTT

Downstream 100 bases:

>100_bases
GCTGGGCAAACAATACTTCTTGGGTCATGTCCTTAGTTCCTTTCATCCGTTCCTTTATTAGAACTTATTTGTTTTTGGGA
TTCCTATTGCCTTCCGTTTT

Product: putative esterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 624; Mature: 624

Protein sequence:

>624_residues
MKRIRKSKNPSLAQYLTLADLFQNLPHSVLREMMDHTVREFLKGGEILFLENSIGSDLYILAAGKLRYEKRGPNGALRDI
GEFKRLDVIGELSLFTGEKRSATVKAVRDSELIRVPREVALSILLKYPDSLLQITKIIAERLAHAKTETKSFLPQAKTFS
LLSSLPEKTILDAIHYLGIVFLRYGSIYVVDESMFNEKTRELEKLDEVDRKPWIIRFFTQIEAEYDYIFYLLKDEDKVSP
FAERALRQSDSFVYIKDANESPSCIQLETLIDKRKYNDRNHILVLIQPNKDEVKPGTIKHLQKRKFHRHFHVHMERMDTW
ERLGRGLLGKSIGLALGGGGAKGFAHLGVLRALEENNIPIDMVSGTSAGSIFAALIAMGESSLSSKTKAKEFWVNKDLLN
EYTLPILSLTTGKKYTEAIRQFFGEIQIEDLWIPYFPVATNLSHSEIHVQEVGSLWKAIRASTSIPGIVPPFIDDGIVYV
DGGVLDNVPGISLKERGVGKVISVDVFGDIYPDQDRELCEYFDSKNPGVMTNPFFQMTNLINFQDLTKPKFPPIGDIIIR
SILASSRERIRQTETISDLFLQIPTNNFGLLDWFAYERLIELGYISSVGKIKMNREKFINPSLQ

Sequences:

>Translated_624_residues
MKRIRKSKNPSLAQYLTLADLFQNLPHSVLREMMDHTVREFLKGGEILFLENSIGSDLYILAAGKLRYEKRGPNGALRDI
GEFKRLDVIGELSLFTGEKRSATVKAVRDSELIRVPREVALSILLKYPDSLLQITKIIAERLAHAKTETKSFLPQAKTFS
LLSSLPEKTILDAIHYLGIVFLRYGSIYVVDESMFNEKTRELEKLDEVDRKPWIIRFFTQIEAEYDYIFYLLKDEDKVSP
FAERALRQSDSFVYIKDANESPSCIQLETLIDKRKYNDRNHILVLIQPNKDEVKPGTIKHLQKRKFHRHFHVHMERMDTW
ERLGRGLLGKSIGLALGGGGAKGFAHLGVLRALEENNIPIDMVSGTSAGSIFAALIAMGESSLSSKTKAKEFWVNKDLLN
EYTLPILSLTTGKKYTEAIRQFFGEIQIEDLWIPYFPVATNLSHSEIHVQEVGSLWKAIRASTSIPGIVPPFIDDGIVYV
DGGVLDNVPGISLKERGVGKVISVDVFGDIYPDQDRELCEYFDSKNPGVMTNPFFQMTNLINFQDLTKPKFPPIGDIIIR
SILASSRERIRQTETISDLFLQIPTNNFGLLDWFAYERLIELGYISSVGKIKMNREKFINPSLQ
>Mature_624_residues
MKRIRKSKNPSLAQYLTLADLFQNLPHSVLREMMDHTVREFLKGGEILFLENSIGSDLYILAAGKLRYEKRGPNGALRDI
GEFKRLDVIGELSLFTGEKRSATVKAVRDSELIRVPREVALSILLKYPDSLLQITKIIAERLAHAKTETKSFLPQAKTFS
LLSSLPEKTILDAIHYLGIVFLRYGSIYVVDESMFNEKTRELEKLDEVDRKPWIIRFFTQIEAEYDYIFYLLKDEDKVSP
FAERALRQSDSFVYIKDANESPSCIQLETLIDKRKYNDRNHILVLIQPNKDEVKPGTIKHLQKRKFHRHFHVHMERMDTW
ERLGRGLLGKSIGLALGGGGAKGFAHLGVLRALEENNIPIDMVSGTSAGSIFAALIAMGESSLSSKTKAKEFWVNKDLLN
EYTLPILSLTTGKKYTEAIRQFFGEIQIEDLWIPYFPVATNLSHSEIHVQEVGSLWKAIRASTSIPGIVPPFIDDGIVYV
DGGVLDNVPGISLKERGVGKVISVDVFGDIYPDQDRELCEYFDSKNPGVMTNPFFQMTNLINFQDLTKPKFPPIGDIIIR
SILASSRERIRQTETISDLFLQIPTNNFGLLDWFAYERLIELGYISSVGKIKMNREKFINPSLQ

Specific function: Unknown

COG id: COG1752

COG function: function code R; Predicted esterase of the alpha-beta hydrolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 patatin domain [H]

Homologues:

Organism=Homo sapiens, GI260656039, Length=619, Percent_Identity=26.1712439418417, Blast_Score=217, Evalue=3e-56,
Organism=Homo sapiens, GI260656037, Length=620, Percent_Identity=26.2903225806452, Blast_Score=217, Evalue=3e-56,
Organism=Homo sapiens, GI260656043, Length=619, Percent_Identity=26.1712439418417, Blast_Score=216, Evalue=4e-56,
Organism=Homo sapiens, GI260656041, Length=620, Percent_Identity=26.2903225806452, Blast_Score=216, Evalue=4e-56,
Organism=Homo sapiens, GI116256487, Length=620, Percent_Identity=26.2903225806452, Blast_Score=216, Evalue=4e-56,
Organism=Homo sapiens, GI148727335, Length=627, Percent_Identity=26.1562998405104, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI148727290, Length=627, Percent_Identity=26.1562998405104, Blast_Score=204, Evalue=2e-52,
Organism=Escherichia coli, GI226510936, Length=184, Percent_Identity=36.9565217391304, Blast_Score=95, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71997289, Length=671, Percent_Identity=26.9746646795827, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71997299, Length=671, Percent_Identity=26.9746646795827, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI193204778, Length=658, Percent_Identity=24.1641337386018, Blast_Score=143, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6323581, Length=336, Percent_Identity=32.1428571428571, Blast_Score=169, Evalue=1e-42,
Organism=Drosophila melanogaster, GI281376913, Length=628, Percent_Identity=28.0254777070064, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI28571388, Length=628, Percent_Identity=27.7070063694268, Blast_Score=204, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016035
- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001423
- InterPro:   IPR002641
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00027 cNMP_binding; PF01734 Patatin [H]

EC number: NA

Molecular weight: Translated: 70958; Mature: 70958

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS00889 CNMP_BINDING_2 ; PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIRKSKNPSLAQYLTLADLFQNLPHSVLREMMDHTVREFLKGGEILFLENSIGSDLYI
CCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEE
LAAGKLRYEKRGPNGALRDIGEFKRLDVIGELSLFTGEKRSATVKAVRDSELIRVPREVA
EEECCEEEECCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHCCCHHHHCCHHHH
LSILLKYPDSLLQITKIIAERLAHAKTETKSFLPQAKTFSLLSSLPEKTILDAIHYLGIV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHH
FLRYGSIYVVDESMFNEKTRELEKLDEVDRKPWIIRFFTQIEAEYDYIFYLLKDEDKVSP
HHHCCCEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCCEEEEEEEECCCCCCCH
FAERALRQSDSFVYIKDANESPSCIQLETLIDKRKYNDRNHILVLIQPNKDEVKPGTIKH
HHHHHHHCCCCEEEEECCCCCCCEEEHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHH
LQKRKFHRHFHVHMERMDTWERLGRGLLGKSIGLALGGGGAKGFAHLGVLRALEENNIPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCEEECCCCCHHHHHHHHHHHHHCCCCCE
DMVSGTSAGSIFAALIAMGESSLSSKTKAKEFWVNKDLLNEYTLPILSLTTGKKYTEAIR
EEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHCCCEEEECCCHHHHHHHH
QFFGEIQIEDLWIPYFPVATNLSHSEIHVQEVGSLWKAIRASTSIPGIVPPFIDDGIVYV
HHHCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEE
DGGVLDNVPGISLKERGVGKVISVDVFGDIYPDQDRELCEYFDSKNPGVMTNPFFQMTNL
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHC
INFQDLTKPKFPPIGDIIIRSILASSRERIRQTETISDLFLQIPTNNFGLLDWFAYERLI
CCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHH
ELGYISSVGKIKMNREKFINPSLQ
HHHHHCCCCCEEECHHHCCCCCCC
>Mature Secondary Structure
MKRIRKSKNPSLAQYLTLADLFQNLPHSVLREMMDHTVREFLKGGEILFLENSIGSDLYI
CCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEE
LAAGKLRYEKRGPNGALRDIGEFKRLDVIGELSLFTGEKRSATVKAVRDSELIRVPREVA
EEECCEEEECCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHCCCHHHHCCHHHH
LSILLKYPDSLLQITKIIAERLAHAKTETKSFLPQAKTFSLLSSLPEKTILDAIHYLGIV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHH
FLRYGSIYVVDESMFNEKTRELEKLDEVDRKPWIIRFFTQIEAEYDYIFYLLKDEDKVSP
HHHCCCEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCCEEEEEEEECCCCCCCH
FAERALRQSDSFVYIKDANESPSCIQLETLIDKRKYNDRNHILVLIQPNKDEVKPGTIKH
HHHHHHHCCCCEEEEECCCCCCCEEEHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHH
LQKRKFHRHFHVHMERMDTWERLGRGLLGKSIGLALGGGGAKGFAHLGVLRALEENNIPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCEEECCCCCHHHHHHHHHHHHHCCCCCE
DMVSGTSAGSIFAALIAMGESSLSSKTKAKEFWVNKDLLNEYTLPILSLTTGKKYTEAIR
EEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHCCCEEEECCCHHHHHHHH
QFFGEIQIEDLWIPYFPVATNLSHSEIHVQEVGSLWKAIRASTSIPGIVPPFIDDGIVYV
HHHCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEE
DGGVLDNVPGISLKERGVGKVISVDVFGDIYPDQDRELCEYFDSKNPGVMTNPFFQMTNL
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHC
INFQDLTKPKFPPIGDIIIRSILASSRERIRQTETISDLFLQIPTNNFGLLDWFAYERLI
CCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHH
ELGYISSVGKIKMNREKFINPSLQ
HHHHHCCCCCEEECHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]