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The map label for this gene is ribD [H]

Identifier: 183220792

GI number: 183220792

Start: 1462568

End: 1463860

Strand: Direct

Name: ribD [H]

Synonym: LEPBI_I1403

Alternate gene names: 183220792

Gene position: 1462568-1463860 (Clockwise)

Preceding gene: 183220791

Following gene: 183220793

Centisome position: 40.63

GC content: 41.3

Gene sequence:

>1293_bases
ATGGATGTAGAGAAAAGGAAGGAACTTTATTCTCTGCATTCCCTTCTTGGGTTTCTTGCCATGGGTAAAACTGGCGGGAA
CCCACCTGTTTCTGCTGTTCTTACAAACTCCATTGGAGAGCCAATCGAAAAGGCCCACACCCAAGGTTATGGCGGAAATC
ATGCCGAAAGGGAATTGTATTCGTTAGTCGAACAAAAACATTCCCATTCCCAAATCCAAACTGACGAAAATTCCCTTTCC
GATACCATTCTATCGGTGAGTCTCGAGCCCTGTACCCATTTTGGGAAAACACCACCTTGCCGTGATTTGGTGCTCCAACA
CAAACCAAAAGAACTCCTACTCGGTTGGAAAGATCCGAATCCCATGGTCCAATCGGGAGACTGGAAACTGTATTTGGAAC
AGGGAACCAAGGTAAGGTTGGATCCAATGCTTGCAAATACCTCACTTCCATATTTGCAAGGGTTTTTGAAACGAATGCAA
ACAGGGAAACCATGGGTTTGGATCAAATCAGCGACTAGCACAGAAGGAAATTACGTTTCCAAATCCTTCACAAAAGAAAG
GGTGAGTTCTATAGAAATGGATTTGTATTTGCAATTGCTTCGCGCAAAATTTGATGCCGTTGCCGTTGGACCCAATACAA
CAAAAGTCGATGAACCTTCCTTACACTTTCGGATCACAGAAGAGATGATCCAATCCGTAGCACCTTGCAAAAGAGAAACG
GAGCTGGTCCCTTTTTTTGAGGCGGCAACCAATCTCTTTTCTTCCCTTTGTCGATGGACAAAAGAGAGTGTTACGATCCA
TCAATTGGAAGAGGAACGATACCAACCCTACCGGGTTTTTGTTTTGGATCCGAATCGAATGCCAAGTGATCATTTTTTTA
CCAAACAAAGGGAACTGAATGAACGATTGGGAAAAAAACTTTGTCTTTTTTTTCTCCTTACCAATTCCATAAAAAAGAAA
GACAACTTGTTTGGGATCTCTAGTCAAATGAAGGAAACATTGGAATCACTTTCGAACACTCACCTGATCTCAGTCAACCA
GGATGAAGGGGATTTGTTTCTGAAGACACTTGGTAAATTGGGGATCAATACCTTGTTATGTGAGGCGGGAAGTTTTTTCC
CAAATTTTCTAAAAGAAAGTTTCACTGACGAAGATTGTACTTTAGAGATTCGTAATCATAAAAAATCCATTCCTGACGGA
ATCCCTTTTGATTTCATTCATGAACCAATTGTTTCGGAATTTAGGGTTGGTTCCAATTCTGTATTTTTTCGAAAAACAAA
TAGGAGAGGTTAA

Upstream 100 bases:

>100_bases
GGTGTCATTGTCGGAACCTATTCTTCCATTTACATTGCAGCACCTATTTCTGAGATCTACGACCGACTCAGGAAAAAAAG
ATTCGCATAACGAAAATTTG

Downstream 100 bases:

>100_bases
TCTATGTTCACTGGTCTTGTGGAAACACTTGGAAAAGTTGTCCAAATTGAACCGATTGACTCGGGAATCCAATTTACCAT
CCAAACGGAATGGGAAAATC

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MDVEKRKELYSLHSLLGFLAMGKTGGNPPVSAVLTNSIGEPIEKAHTQGYGGNHAERELYSLVEQKHSHSQIQTDENSLS
DTILSVSLEPCTHFGKTPPCRDLVLQHKPKELLLGWKDPNPMVQSGDWKLYLEQGTKVRLDPMLANTSLPYLQGFLKRMQ
TGKPWVWIKSATSTEGNYVSKSFTKERVSSIEMDLYLQLLRAKFDAVAVGPNTTKVDEPSLHFRITEEMIQSVAPCKRET
ELVPFFEAATNLFSSLCRWTKESVTIHQLEEERYQPYRVFVLDPNRMPSDHFFTKQRELNERLGKKLCLFFLLTNSIKKK
DNLFGISSQMKETLESLSNTHLISVNQDEGDLFLKTLGKLGINTLLCEAGSFFPNFLKESFTDEDCTLEIRNHKKSIPDG
IPFDFIHEPIVSEFRVGSNSVFFRKTNRRG

Sequences:

>Translated_430_residues
MDVEKRKELYSLHSLLGFLAMGKTGGNPPVSAVLTNSIGEPIEKAHTQGYGGNHAERELYSLVEQKHSHSQIQTDENSLS
DTILSVSLEPCTHFGKTPPCRDLVLQHKPKELLLGWKDPNPMVQSGDWKLYLEQGTKVRLDPMLANTSLPYLQGFLKRMQ
TGKPWVWIKSATSTEGNYVSKSFTKERVSSIEMDLYLQLLRAKFDAVAVGPNTTKVDEPSLHFRITEEMIQSVAPCKRET
ELVPFFEAATNLFSSLCRWTKESVTIHQLEEERYQPYRVFVLDPNRMPSDHFFTKQRELNERLGKKLCLFFLLTNSIKKK
DNLFGISSQMKETLESLSNTHLISVNQDEGDLFLKTLGKLGINTLLCEAGSFFPNFLKESFTDEDCTLEIRNHKKSIPDG
IPFDFIHEPIVSEFRVGSNSVFFRKTNRRG
>Mature_430_residues
MDVEKRKELYSLHSLLGFLAMGKTGGNPPVSAVLTNSIGEPIEKAHTQGYGGNHAERELYSLVEQKHSHSQIQTDENSLS
DTILSVSLEPCTHFGKTPPCRDLVLQHKPKELLLGWKDPNPMVQSGDWKLYLEQGTKVRLDPMLANTSLPYLQGFLKRMQ
TGKPWVWIKSATSTEGNYVSKSFTKERVSSIEMDLYLQLLRAKFDAVAVGPNTTKVDEPSLHFRITEEMIQSVAPCKRET
ELVPFFEAATNLFSSLCRWTKESVTIHQLEEERYQPYRVFVLDPNRMPSDHFFTKQRELNERLGKKLCLFFLLTNSIKKK
DNLFGISSQMKETLESLSNTHLISVNQDEGDLFLKTLGKLGINTLLCEAGSFFPNFLKESFTDEDCTLEIRNHKKSIPDG
IPFDFIHEPIVSEFRVGSNSVFFRKTNRRG

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=211, Percent_Identity=29.8578199052133, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 49001; Mature: 49001

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVEKRKELYSLHSLLGFLAMGKTGGNPPVSAVLTNSIGEPIEKAHTQGYGGNHAERELY
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHH
SLVEQKHSHSQIQTDENSLSDTILSVSLEPCTHFGKTPPCRDLVLQHKPKELLLGWKDPN
HHHHHHHCCCCCCCCCHHHHHHHHEEEECHHHHCCCCCCHHHHHHCCCCHHHEEECCCCC
PMVQSGDWKLYLEQGTKVRLDPMLANTSLPYLQGFLKRMQTGKPWVWIKSATSTEGNYVS
CCCCCCCEEEEEECCCEEEECCHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHH
KSFTKERVSSIEMDLYLQLLRAKFDAVAVGPNTTKVDEPSLHFRITEEMIQSVAPCKRET
HHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCEEEEEHHHHHHHHCCCCCCC
ELVPFFEAATNLFSSLCRWTKESVTIHQLEEERYQPYRVFVLDPNRMPSDHFFTKQRELN
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHH
ERLGKKLCLFFLLTNSIKKKDNLFGISSQMKETLESLSNTHLISVNQDEGDLFLKTLGKL
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHH
GINTLLCEAGSFFPNFLKESFTDEDCTLEIRNHKKSIPDGIPFDFIHEPIVSEFRVGSNS
HHHHHHHCCCCCCHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
VFFRKTNRRG
EEEEECCCCC
>Mature Secondary Structure
MDVEKRKELYSLHSLLGFLAMGKTGGNPPVSAVLTNSIGEPIEKAHTQGYGGNHAERELY
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHH
SLVEQKHSHSQIQTDENSLSDTILSVSLEPCTHFGKTPPCRDLVLQHKPKELLLGWKDPN
HHHHHHHCCCCCCCCCHHHHHHHHEEEECHHHHCCCCCCHHHHHHCCCCHHHEEECCCCC
PMVQSGDWKLYLEQGTKVRLDPMLANTSLPYLQGFLKRMQTGKPWVWIKSATSTEGNYVS
CCCCCCCEEEEEECCCEEEECCHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHH
KSFTKERVSSIEMDLYLQLLRAKFDAVAVGPNTTKVDEPSLHFRITEEMIQSVAPCKRET
HHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCEEEEEHHHHHHHHCCCCCCC
ELVPFFEAATNLFSSLCRWTKESVTIHQLEEERYQPYRVFVLDPNRMPSDHFFTKQRELN
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHH
ERLGKKLCLFFLLTNSIKKKDNLFGISSQMKETLESLSNTHLISVNQDEGDLFLKTLGKL
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHH
GINTLLCEAGSFFPNFLKESFTDEDCTLEIRNHKKSIPDGIPFDFIHEPIVSEFRVGSNS
HHHHHHHCCCCCCHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
VFFRKTNRRG
EEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 2112225; 9068650 [H]