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The map label for this gene is nhaA2 [H]

Identifier: 183220540

GI number: 183220540

Start: 1191250

End: 1192299

Strand: Direct

Name: nhaA2 [H]

Synonym: LEPBI_I1143

Alternate gene names: 183220540

Gene position: 1191250-1192299 (Clockwise)

Preceding gene: 183220537

Following gene: 183220541

Centisome position: 33.09

GC content: 37.71

Gene sequence:

>1050_bases
ATGGAAAATAATTTTAAATCGTGGATGGCCCAGCCCATCTCTAAAATCTTCATAGGCACCAATTTGGTCTTCGCTCTGCT
TTTTTTTGTCAGTGTTCCTTCCTTTGTGAAAGAATACATCACCCAGGATGCCGTAAGCATCGGAGGTAAAAAATATGACC
TCAGTGATGTGAAGAACTCCTCTCCGATTGCCTATTCTAAATTCCAATCTGAGTACAAATCCCTTCTCAAAAATACATTT
GGTGAATTTGCCCAAGACAAATTATTCGAACTTGTTGCCAAAGACAGAAATATCAAACCTTCAGAAGTATTGAACGAAGG
ATTGATTTTAAGAGAACCTTCGGAAGAAGATATTATCAATGTTTATATGTCAAACAAAGCTCAGTTAGGTGGGAAGTCTC
TCGCTGAAACAAGAGAAAAAATTGTGGGATTTTTAAAAAACCAACAGGAACAAGAACATAGCCGAAACAAATACCGTGAA
ATCATCACCAAATACCCTGTTGATTTTTTGATCAAAGAACCAGAAGCGATTCGAGTCACTGTTGATGAAAAAAATAACCC
AAGCATTGGACCAAAAGATGCCAAAGTCACTGTGATTGAATTTTCTGATTTCGAGTGCCCTTTCTGCAAACGAAGCCAAG
ATGTAAATAACCAACTCCGAGAAAAATACAAAGGCCAAATCCGTTGGGTTTTCCGTGACTTTCCACTACCTTTCCACCAA
GATGCGATGTATGCACATATGGCTGCCAATTGTTCTATTGAAGAAGGTAAGTATTGGGATGTGTTCAATGTTTTATTTGA
GAACAGTGGAAACCTAAGTAAATCCAAAGTGGATGAATTTGTTCTCAAAACAGGACTTTCTAAAGAGAAATACCAATCTT
GTATGAAAGACCAATCGAAATTAAAGAGCGAAATCGAAGCCGATATCCAAGATGGTCAAAAGGTCGGAGTGAGTGGTACA
CCTGCATTTTTTATCAATGGGATCTTTGTATCAGGTGCCTTACCATTTGAAAACTTCGATGAGATCATCCAAAAAGAACT
GAAACAATAA

Upstream 100 bases:

>100_bases
AGATTTTCGGTCTTTTGATCCTTAGCTTTAGCGAAAATAGAAGATTTTTTTAGGATTTTTCGGTTTGATTGCCCGCTTTA
TGGGCGGGAAGCTGGCAGAG

Downstream 100 bases:

>100_bases
AGGATTATAAACCAAAAAGGAAAAATTATATGAGCAAAAAAGTGAAAGTTGCTGTAACAGGTGCAGCCGGACAAATCGGA
TATGCACTTTTATTTCGTAT

Product: hypothetical protein

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 2 [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MENNFKSWMAQPISKIFIGTNLVFALLFFVSVPSFVKEYITQDAVSIGGKKYDLSDVKNSSPIAYSKFQSEYKSLLKNTF
GEFAQDKLFELVAKDRNIKPSEVLNEGLILREPSEEDIINVYMSNKAQLGGKSLAETREKIVGFLKNQQEQEHSRNKYRE
IITKYPVDFLIKEPEAIRVTVDEKNNPSIGPKDAKVTVIEFSDFECPFCKRSQDVNNQLREKYKGQIRWVFRDFPLPFHQ
DAMYAHMAANCSIEEGKYWDVFNVLFENSGNLSKSKVDEFVLKTGLSKEKYQSCMKDQSKLKSEIEADIQDGQKVGVSGT
PAFFINGIFVSGALPFENFDEIIQKELKQ

Sequences:

>Translated_349_residues
MENNFKSWMAQPISKIFIGTNLVFALLFFVSVPSFVKEYITQDAVSIGGKKYDLSDVKNSSPIAYSKFQSEYKSLLKNTF
GEFAQDKLFELVAKDRNIKPSEVLNEGLILREPSEEDIINVYMSNKAQLGGKSLAETREKIVGFLKNQQEQEHSRNKYRE
IITKYPVDFLIKEPEAIRVTVDEKNNPSIGPKDAKVTVIEFSDFECPFCKRSQDVNNQLREKYKGQIRWVFRDFPLPFHQ
DAMYAHMAANCSIEEGKYWDVFNVLFENSGNLSKSKVDEFVLKTGLSKEKYQSCMKDQSKLKSEIEADIQDGQKVGVSGT
PAFFINGIFVSGALPFENFDEIIQKELKQ
>Mature_349_residues
MENNFKSWMAQPISKIFIGTNLVFALLFFVSVPSFVKEYITQDAVSIGGKKYDLSDVKNSSPIAYSKFQSEYKSLLKNTF
GEFAQDKLFELVAKDRNIKPSEVLNEGLILREPSEEDIINVYMSNKAQLGGKSLAETREKIVGFLKNQQEQEHSRNKYRE
IITKYPVDFLIKEPEAIRVTVDEKNNPSIGPKDAKVTVIEFSDFECPFCKRSQDVNNQLREKYKGQIRWVFRDFPLPFHQ
DAMYAHMAANCSIEEGKYWDVFNVLFENSGNLSKSKVDEFVLKTGLSKEKYQSCMKDQSKLKSEIEADIQDGQKVGVSGT
PAFFINGIFVSGALPFENFDEIIQKELKQ

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 39960; Mature: 39960

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENNFKSWMAQPISKIFIGTNLVFALLFFVSVPSFVKEYITQDAVSIGGKKYDLSDVKNS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHCCCC
SPIAYSKFQSEYKSLLKNTFGEFAQDKLFELVAKDRNIKPSEVLNEGLILREPSEEDIIN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCEEECCCCCCEEE
VYMSNKAQLGGKSLAETREKIVGFLKNQQEQEHSRNKYREIITKYPVDFLIKEPEAIRVT
EEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCCCEEEEE
VDEKNNPSIGPKDAKVTVIEFSDFECPFCKRSQDVNNQLREKYKGQIRWVFRDFPLPFHQ
EECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCC
DAMYAHMAANCSIEEGKYWDVFNVLFENSGNLSKSKVDEFVLKTGLSKEKYQSCMKDQSK
HHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
LKSEIEADIQDGQKVGVSGTPAFFINGIFVSGALPFENFDEIIQKELKQ
HHHHHHHHHHCCCEECCCCCCHHEEEEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MENNFKSWMAQPISKIFIGTNLVFALLFFVSVPSFVKEYITQDAVSIGGKKYDLSDVKNS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHCCCC
SPIAYSKFQSEYKSLLKNTFGEFAQDKLFELVAKDRNIKPSEVLNEGLILREPSEEDIIN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCEEECCCCCCEEE
VYMSNKAQLGGKSLAETREKIVGFLKNQQEQEHSRNKYREIITKYPVDFLIKEPEAIRVT
EEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCCCEEEEE
VDEKNNPSIGPKDAKVTVIEFSDFECPFCKRSQDVNNQLREKYKGQIRWVFRDFPLPFHQ
EECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCC
DAMYAHMAANCSIEEGKYWDVFNVLFENSGNLSKSKVDEFVLKTGLSKEKYQSCMKDQSK
HHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
LKSEIEADIQDGQKVGVSGTPAFFINGIFVSGALPFENFDEIIQKELKQ
HHHHHHHHHHCCCEECCCCCCHHEEEEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA