| Definition | Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_010602 |
| Length | 3,599,677 |
Click here to switch to the map view.
The map label for this gene is crt [H]
Identifier: 183220331
GI number: 183220331
Start: 959565
End: 960329
Strand: Direct
Name: crt [H]
Synonym: LEPBI_I0927
Alternate gene names: 183220331
Gene position: 959565-960329 (Clockwise)
Preceding gene: 183220330
Following gene: 183220332
Centisome position: 26.66
GC content: 44.05
Gene sequence:
>765_bases TTGTCTTTTTTAGAGATCCAAATCAAAACCAATTTTGCCCTCGTTACCATCAAAAGACCAGAAGCTCTCAATGCGCTCAA CGATGTTGTGATCACTGAAATTGGCGCCATGGTCGACGAATTAGAATCCAACTCTCAAGTGAGAGGATTTATTTTGACCG GCGAAGGGAAAGCTTTTGTGGCCGGGGCTGACATAGCCAAAATGAAAGAGTTCAATGTCAAAGAAGGCCAGGCATTTTCG GAACTCGGACAAACCGTATTTCGCAAAATGGAATTATCCGGTCTGATCTCCATCGCTGCCATCAATGGATTTTGTTTGGG TGGTGGAATGGAACTCGCAATGGCATGTGACATTCGTTATGCGTCAACTGTAGCCAAGTTAGGTCTTCCTGAAGTGACTT TGGGTTTACTTCCTGGTTTTGGTGGCTCCCAAAGACTCCCAAGACTCATTGGGGTAGGAAGGGCAACCGAACTCATTTTA TCGGGAGACATGATTTCTTCTGAAGAAGGATTTCGACTCGGCCTTGTGAATAAGGTTTGTGACCCTGCTGAACTTTTAAA CGAATCCGAAAAAACACTTTCCACGATTTTATCCAGAGGGCCTAACGCAATTAAGGCGGCAAAAACGGCTATCCGCCAAG GATTGGAAACCAATATGGATCGTGGTCTTGGATGGGAAAAACAATTGTTTGGTGGAAGATTCGCAGATCAGGAAACAAAA GAAGGTCTCTCTGCTTTCCTCGAAAAAAGGAAACCTAATTTTTAA
Upstream 100 bases:
>100_bases CGCAACTCCTCGATGAATTAAAAACCAAATATGGCCTTGATACTTTTTCAGATGACACAATGTTCCTCATTTTAGAAGTA GAAGAATAAGGAGAAATCAT
Downstream 100 bases:
>100_bases GGGAATGGTTATGTTCACACGGTTTTGTTTGTCTTTCCTATTGTTTTTGGTGGTTGTTTGCAAACAGGCGGAATCCTTTC CGTCGCAAACGAATACCCCT
Product: 3-hydroxybutyryl-CoA dehydratase
Products: NA
Alternate protein names: Crotonase [H]
Number of amino acids: Translated: 254; Mature: 253
Protein sequence:
>254_residues MSFLEIQIKTNFALVTIKRPEALNALNDVVITEIGAMVDELESNSQVRGFILTGEGKAFVAGADIAKMKEFNVKEGQAFS ELGQTVFRKMELSGLISIAAINGFCLGGGMELAMACDIRYASTVAKLGLPEVTLGLLPGFGGSQRLPRLIGVGRATELIL SGDMISSEEGFRLGLVNKVCDPAELLNESEKTLSTILSRGPNAIKAAKTAIRQGLETNMDRGLGWEKQLFGGRFADQETK EGLSAFLEKRKPNF
Sequences:
>Translated_254_residues MSFLEIQIKTNFALVTIKRPEALNALNDVVITEIGAMVDELESNSQVRGFILTGEGKAFVAGADIAKMKEFNVKEGQAFS ELGQTVFRKMELSGLISIAAINGFCLGGGMELAMACDIRYASTVAKLGLPEVTLGLLPGFGGSQRLPRLIGVGRATELIL SGDMISSEEGFRLGLVNKVCDPAELLNESEKTLSTILSRGPNAIKAAKTAIRQGLETNMDRGLGWEKQLFGGRFADQETK EGLSAFLEKRKPNF >Mature_253_residues SFLEIQIKTNFALVTIKRPEALNALNDVVITEIGAMVDELESNSQVRGFILTGEGKAFVAGADIAKMKEFNVKEGQAFSE LGQTVFRKMELSGLISIAAINGFCLGGGMELAMACDIRYASTVAKLGLPEVTLGLLPGFGGSQRLPRLIGVGRATELILS GDMISSEEGFRLGLVNKVCDPAELLNESEKTLSTILSRGPNAIKAAKTAIRQGLETNMDRGLGWEKQLFGGRFADQETKE GLSAFLEKRKPNF
Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]
COG id: COG1024
COG function: function code I; Enoyl-CoA hydratase/carnithine racemase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]
Homologues:
Organism=Homo sapiens, GI194097323, Length=241, Percent_Identity=38.5892116182573, Blast_Score=170, Evalue=1e-42, Organism=Homo sapiens, GI4502327, Length=243, Percent_Identity=36.2139917695473, Blast_Score=119, Evalue=4e-27, Organism=Homo sapiens, GI20127408, Length=180, Percent_Identity=36.6666666666667, Blast_Score=117, Evalue=1e-26, Organism=Homo sapiens, GI150378541, Length=245, Percent_Identity=33.0612244897959, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI68989263, Length=183, Percent_Identity=34.9726775956284, Blast_Score=104, Evalue=7e-23, Organism=Homo sapiens, GI157694516, Length=233, Percent_Identity=27.4678111587983, Blast_Score=102, Evalue=5e-22, Organism=Homo sapiens, GI213417737, Length=233, Percent_Identity=27.4678111587983, Blast_Score=101, Evalue=5e-22, Organism=Homo sapiens, GI70995211, Length=250, Percent_Identity=26.4, Blast_Score=93, Evalue=3e-19, Organism=Homo sapiens, GI157694520, Length=198, Percent_Identity=28.7878787878788, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI31542718, Length=245, Percent_Identity=26.1224489795918, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI261878539, Length=81, Percent_Identity=54.320987654321, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI62530384, Length=242, Percent_Identity=23.5537190082645, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI37594471, Length=216, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI37594469, Length=216, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=4e-12, Organism=Escherichia coli, GI1787659, Length=258, Percent_Identity=37.2093023255814, Blast_Score=166, Evalue=1e-42, Organism=Escherichia coli, GI1788682, Length=189, Percent_Identity=40.7407407407407, Blast_Score=130, Evalue=6e-32, Organism=Escherichia coli, GI1790281, Length=204, Percent_Identity=32.3529411764706, Blast_Score=119, Evalue=1e-28, Organism=Escherichia coli, GI221142681, Length=246, Percent_Identity=30.8943089430894, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI1787660, Length=264, Percent_Identity=32.1969696969697, Blast_Score=101, Evalue=6e-23, Organism=Escherichia coli, GI1788597, Length=247, Percent_Identity=26.7206477732794, Blast_Score=88, Evalue=6e-19, Organism=Escherichia coli, GI87082183, Length=261, Percent_Identity=25.6704980842912, Blast_Score=81, Evalue=7e-17, Organism=Caenorhabditis elegans, GI25145438, Length=249, Percent_Identity=39.7590361445783, Blast_Score=171, Evalue=3e-43, Organism=Caenorhabditis elegans, GI17554946, Length=246, Percent_Identity=37.8048780487805, Blast_Score=170, Evalue=6e-43, Organism=Caenorhabditis elegans, GI17540714, Length=221, Percent_Identity=37.5565610859729, Blast_Score=144, Evalue=6e-35, Organism=Caenorhabditis elegans, GI17558304, Length=228, Percent_Identity=34.2105263157895, Blast_Score=118, Evalue=4e-27, Organism=Caenorhabditis elegans, GI25144276, Length=223, Percent_Identity=36.7713004484305, Blast_Score=117, Evalue=4e-27, Organism=Caenorhabditis elegans, GI17508953, Length=228, Percent_Identity=35.9649122807018, Blast_Score=117, Evalue=4e-27, Organism=Caenorhabditis elegans, GI17508951, Length=228, Percent_Identity=35.9649122807018, Blast_Score=117, Evalue=5e-27, Organism=Caenorhabditis elegans, GI17534483, Length=254, Percent_Identity=27.9527559055118, Blast_Score=112, Evalue=3e-25, Organism=Caenorhabditis elegans, GI17560910, Length=242, Percent_Identity=30.5785123966942, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17536985, Length=256, Percent_Identity=26.5625, Blast_Score=96, Evalue=3e-20, Organism=Caenorhabditis elegans, GI25141363, Length=220, Percent_Identity=29.0909090909091, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI25144157, Length=211, Percent_Identity=33.175355450237, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI25144160, Length=211, Percent_Identity=33.175355450237, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17540306, Length=241, Percent_Identity=26.5560165975104, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17549921, Length=248, Percent_Identity=24.1935483870968, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6320241, Length=199, Percent_Identity=26.1306532663317, Blast_Score=67, Evalue=2e-12, Organism=Drosophila melanogaster, GI20129971, Length=248, Percent_Identity=38.3064516129032, Blast_Score=171, Evalue=4e-43, Organism=Drosophila melanogaster, GI24653477, Length=248, Percent_Identity=38.3064516129032, Blast_Score=171, Evalue=4e-43, Organism=Drosophila melanogaster, GI24653139, Length=251, Percent_Identity=31.4741035856574, Blast_Score=131, Evalue=5e-31, Organism=Drosophila melanogaster, GI24583077, Length=185, Percent_Identity=39.4594594594595, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI24583079, Length=185, Percent_Identity=39.4594594594595, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI19921000, Length=185, Percent_Identity=39.4594594594595, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI19920382, Length=259, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI21357171, Length=259, Percent_Identity=25.8687258687259, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24654903, Length=235, Percent_Identity=23.8297872340426, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI19922422, Length=244, Percent_Identity=22.5409836065574, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24583165, Length=189, Percent_Identity=31.2169312169312, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI24650670, Length=177, Percent_Identity=28.2485875706215, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI19921018, Length=189, Percent_Identity=30.1587301587302, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI28571729, Length=196, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI28571730, Length=196, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=3e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR014748 - InterPro: IPR001753 - InterPro: IPR018376 [H]
Pfam domain/function: PF00378 ECH [H]
EC number: =4.2.1.55 [H]
Molecular weight: Translated: 27349; Mature: 27218
Theoretical pI: Translated: 5.22; Mature: 5.22
Prosite motif: PS00166 ENOYL_COA_HYDRATASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 4.3 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 4.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSFLEIQIKTNFALVTIKRPEALNALNDVVITEIGAMVDELESNSQVRGFILTGEGKAFV CCEEEEEEECCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEE AGADIAKMKEFNVKEGQAFSELGQTVFRKMELSGLISIAAINGFCLGGGMELAMACDIRY ECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCEEECCCCEEEEEECCHH ASTVAKLGLPEVTLGLLPGFGGSQRLPRLIGVGRATELILSGDMISSEEGFRLGLVNKVC HHHHHHCCCCHHHHHHCCCCCCCCCCHHHHCCCCHHHEEEECCCCCCCCCCEEECHHHCC DPAELLNESEKTLSTILSRGPNAIKAAKTAIRQGLETNMDRGLGWEKQLFGGRFADQETK CHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHCCCHHHHHHCCCCCCHHHH EGLSAFLEKRKPNF HHHHHHHHHHCCCC >Mature Secondary Structure SFLEIQIKTNFALVTIKRPEALNALNDVVITEIGAMVDELESNSQVRGFILTGEGKAFV CEEEEEEECCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEE AGADIAKMKEFNVKEGQAFSELGQTVFRKMELSGLISIAAINGFCLGGGMELAMACDIRY ECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCEEECCCCEEEEEECCHH ASTVAKLGLPEVTLGLLPGFGGSQRLPRLIGVGRATELILSGDMISSEEGFRLGLVNKVC HHHHHHCCCCHHHHHHCCCCCCCCCCHHHHCCCCHHHEEEECCCCCCCCCCEEECHHHCC DPAELLNESEKTLSTILSRGPNAIKAAKTAIRQGLETNMDRGLGWEKQLFGGRFADQETK CHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHCCCHHHHHHCCCCCCHHHH EGLSAFLEKRKPNF HHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8655474; 11466286 [H]