Click here to switch to the map view.

The map label for this gene is cheB1 [H]

Identifier: 183220323

GI number: 183220323

Start: 950175

End: 951218

Strand: Reverse

Name: cheB1 [H]

Synonym: LEPBI_I0919

Alternate gene names: 183220323

Gene position: 951218-950175 (Counterclockwise)

Preceding gene: 183220324

Following gene: 183220322

Centisome position: 26.43

GC content: 40.13

Gene sequence:

>1044_bases
ATGAAAAAAAACAAAGTGATTATCGTAGATGACCAACGTACAGTGCGCGGAATGATCAAACGTTGGATCGAATCAGATCC
AAACTGGGAAGTTGTAGGCGAGGCATCAAACCCATTCGAAGCTCGTGACCAAATCATCGAAAAACAACCTGATGTGATGA
CATTAGATGTTCATATGCCCGAAATGGATGGAATCGAATTTTTAAAAAAGCTCCTCCCCCAACACCCAATGCCTGTGATC
ATGTTTAGTTCTTCCACAACGGAAGGGACTGCAATCACCTTAGAAGCTCTTGATGCGGGTGCCTTTGACTATGTAACAAA
GCCTTCAGGAACTCCAGAAAGTTTGATTGAAGCAAAAGAAGATTTGTTAAGTAAGTTGCATGCGGCCTTGAACTACAATG
TATCACTTTATCAAAATACGAAAAGCACTACCCCATCGAAAATTTTATCAGCGAAAAGACACACATCTTTTAAAACCAAA
GTCATCGTCATAGGATCCAGTACAGGTGGAACAACCGCTTTACGAAAACTATTAGATGATGTGGATGAATCTTTTCCACC
GATCCTTGTTGCACAACATATGCCAGAAAATTTCACTGCCCTATTTGCAGGCAGACTCAACGCAGAATTAAAAGTAAAAG
TCATTGAGGCAAAAGACAAACAGTTATTAGAAAATGGAACCGTTTACATTGCGCCAGGAAATTTCCACCTAGAAATCCAA
AAACTCAATGGAGAACTCTATACCAAAATCACTCAGTTCGAAAAAGTAAATGGCCATAGACCTTCCGTAGACGTCCTATT
TGATTCTGTTGTTAACTGTGGGATTGCCAACCAAACCATCTCCATCATCCTCACTGGTATGGGAAGCGATGGTGCAAAGG
GATTGCTTAATTTAAAGAATAATGGAAGCATCACCTTGGGCCAAAATAAAGAAACCTGTGTTGTTTATGGTATGCCAAAA
GTTGCATTTGAAATAGGTGCTGTGATGTACCAACTTCCTTTGGAATCCATTGCAGATAAAACAAGAGAGATCGGTTCCAA
ATGA

Upstream 100 bases:

>100_bases
TCAATGGTTTGGCTGGTTGTACGATTTTAGGAAACGGACATGCCGGTCTCATTCTCGATGTAAGAAAACTGATCAACCAA
CATATGGCAATCCACTCTCC

Downstream 100 bases:

>100_bases
TTCCTCATAGCCTTGTATTAAGTTCACAAACAACGGATCAATTAATCCATATTTTAAACGAGATCCATTTTACCTACGAA
CGTTTCGAAAATTTAAGTGA

Product: chemotaxis response regulator CheB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MKKNKVIIVDDQRTVRGMIKRWIESDPNWEVVGEASNPFEARDQIIEKQPDVMTLDVHMPEMDGIEFLKKLLPQHPMPVI
MFSSSTTEGTAITLEALDAGAFDYVTKPSGTPESLIEAKEDLLSKLHAALNYNVSLYQNTKSTTPSKILSAKRHTSFKTK
VIVIGSSTGGTTALRKLLDDVDESFPPILVAQHMPENFTALFAGRLNAELKVKVIEAKDKQLLENGTVYIAPGNFHLEIQ
KLNGELYTKITQFEKVNGHRPSVDVLFDSVVNCGIANQTISIILTGMGSDGAKGLLNLKNNGSITLGQNKETCVVYGMPK
VAFEIGAVMYQLPLESIADKTREIGSK

Sequences:

>Translated_347_residues
MKKNKVIIVDDQRTVRGMIKRWIESDPNWEVVGEASNPFEARDQIIEKQPDVMTLDVHMPEMDGIEFLKKLLPQHPMPVI
MFSSSTTEGTAITLEALDAGAFDYVTKPSGTPESLIEAKEDLLSKLHAALNYNVSLYQNTKSTTPSKILSAKRHTSFKTK
VIVIGSSTGGTTALRKLLDDVDESFPPILVAQHMPENFTALFAGRLNAELKVKVIEAKDKQLLENGTVYIAPGNFHLEIQ
KLNGELYTKITQFEKVNGHRPSVDVLFDSVVNCGIANQTISIILTGMGSDGAKGLLNLKNNGSITLGQNKETCVVYGMPK
VAFEIGAVMYQLPLESIADKTREIGSK
>Mature_347_residues
MKKNKVIIVDDQRTVRGMIKRWIESDPNWEVVGEASNPFEARDQIIEKQPDVMTLDVHMPEMDGIEFLKKLLPQHPMPVI
MFSSSTTEGTAITLEALDAGAFDYVTKPSGTPESLIEAKEDLLSKLHAALNYNVSLYQNTKSTTPSKILSAKRHTSFKTK
VIVIGSSTGGTTALRKLLDDVDESFPPILVAQHMPENFTALFAGRLNAELKVKVIEAKDKQLLENGTVYIAPGNFHLEIQ
KLNGELYTKITQFEKVNGHRPSVDVLFDSVVNCGIANQTISIILTGMGSDGAKGLLNLKNNGSITLGQNKETCVVYGMPK
VAFEIGAVMYQLPLESIADKTREIGSK

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR [H]

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788192, Length=344, Percent_Identity=41.2790697674419, Blast_Score=257, Evalue=9e-70,
Organism=Escherichia coli, GI87082052, Length=104, Percent_Identity=35.5769230769231, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1786911, Length=124, Percent_Identity=33.8709677419355, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790299, Length=120, Percent_Identity=32.5, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg [H]

EC number: =3.1.1.61 [H]

Molecular weight: Translated: 38161; Mature: 38161

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50122 CHEB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNKVIIVDDQRTVRGMIKRWIESDPNWEVVGEASNPFEARDQIIEKQPDVMTLDVHMP
CCCCCEEEEECCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEEECC
EMDGIEFLKKLLPQHPMPVIMFSSSTTEGTAITLEALDAGAFDYVTKPSGTPESLIEAKE
CCCHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCEEECCCCCHHHHHHHHH
DLLSKLHAALNYNVSLYQNTKSTTPSKILSAKRHTSFKTKVIVIGSSTGGTTALRKLLDD
HHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHH
VDESFPPILVAQHMPENFTALFAGRLNAELKVKVIEAKDKQLLENGTVYIAPGNFHLEIQ
HHHCCCCEEEECCCCCCCEEEEEECCCCEEEEEEEECCCHHHHHCCEEEEECCCEEEEEE
KLNGELYTKITQFEKVNGHRPSVDVLFDSVVNCGIANQTISIILTGMGSDGAKGLLNLKN
ECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCEEEECC
NGSITLGQNKETCVVYGMPKVAFEIGAVMYQLPLESIADKTREIGSK
CCCEEECCCCCEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKNKVIIVDDQRTVRGMIKRWIESDPNWEVVGEASNPFEARDQIIEKQPDVMTLDVHMP
CCCCCEEEEECCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEEECC
EMDGIEFLKKLLPQHPMPVIMFSSSTTEGTAITLEALDAGAFDYVTKPSGTPESLIEAKE
CCCHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCEEECCCCCHHHHHHHHH
DLLSKLHAALNYNVSLYQNTKSTTPSKILSAKRHTSFKTKVIVIGSSTGGTTALRKLLDD
HHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHH
VDESFPPILVAQHMPENFTALFAGRLNAELKVKVIEAKDKQLLENGTVYIAPGNFHLEIQ
HHHCCCCEEEECCCCCCCEEEEEECCCCEEEEEEEECCCHHHHHCCEEEEECCCEEEEEE
KLNGELYTKITQFEKVNGHRPSVDVLFDSVVNCGIANQTISIILTGMGSDGAKGLLNLKN
ECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCEEEECC
NGSITLGQNKETCVVYGMPKVAFEIGAVMYQLPLESIADKTREIGSK
CCCEEECCCCCEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]