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The map label for this gene is crtI [H]

Identifier: 183220301

GI number: 183220301

Start: 917236

End: 918819

Strand: Direct

Name: crtI [H]

Synonym: LEPBI_I0896

Alternate gene names: 183220301

Gene position: 917236-918819 (Clockwise)

Preceding gene: 183220297

Following gene: 183220302

Centisome position: 25.48

GC content: 39.96

Gene sequence:

>1584_bases
TTGCAATCTTTACACTGTAAAGATTGGTTGGAGTGGAAAGGGAATACCTTTGGGGAGAACAGAATGTCTCATTATGATAC
GGTTGTCATAGGTGCTGGTAACGCAGGTTTAATGGCGGCAACTCGTTTGCAACGGGAGGGTTCTAAAACACTCTTGTTAG
AACGGCATAATGTTCCTGGAGGTTGTGCTACTTCATTTGTCCGAGGGGAATTTGAATTTGAGGTTGCTCTCCACCAACTC
AGCGGTGTCGGGACGGAATCGAATCCATTCATTATGCGTCGTGTTTTTGATGAACTTGGAGTATTGGATAAAATCGAACT
TGTACAAGAAAAAGAACTCTATCGGATCATCATGCCAGGTAGGTTGGATGTTACCTTACCTGCCGATTGGATAGAATTAC
AGAATCATTTAAAAAGTCTTTTTCCTATGGAAACGGATCCAATTGAAAGGTTCTTCAAATTGAGCGAAGCCATCGTCAAC
GAATATTACTTTGTCCTACCTCGAGTGAAATTGTCCAATGACGAAGAAAAAATCAGAATCAAATGCCCAAATTTTTCAGC
ATATGGACTTCGTCCAACAACTGATGTTTTGAATGAATTTTTTTCTACAGAGGATTTAATTAATGTTATCACACCTTATT
GGAGTTATGTTGGAATCCCTACAACAGATTTAGTATTCGCAGAATTTATCGGTATGATATATTTTTACTGTGTGTATAAA
CCTTGGCATATCAAAGGTGGGTCTCAAATGCTTTCGAGCGCTCTGCTTTCCTCATTTGAAGAAGCAGGTGGAGAAGTAAG
ATTTCATTGTTCTGCAGAAAAAATTCTTACAAAAGATGGAGTCGTGTCAGGGGTTCGATTGGAAACAGGAGAAACAGTTA
CCTGTGACGCAGTTGTATCAAATGCAAGTCCTCTCATCACTTATCATGAATTGTTAGATTTAGAAACTCTACCACCGTCT
GTAGTAAAAGATTTTAAATCGAGACGAATGGGAGTATCTGCTGTTTGCCTATATTTGGGTTTAGATTGTTCTCCAGAAGA
AATAGGGTTCACGTCTGCGTCTAGCTTTGTGATGACAACTTCAAATGCAGAGGTCACAGAAGATCGGATGTATACTTTGG
AGGCTCCGGATTGGGGAATGGTCACTTGTTATAACTTTATAGATGAAGAACTTGCCCCAAAAGGAAAGTCCGTTGTCACT
CTTGTCGCTTTACAGTACGGTGAAGCTTGGAAGGATGTTCCACCAGAAGATTACATTGCCACAAAATACGAATTTGGCGA
CAAATTAATTGATCTCATTGAACAAGCGTATCCAAAGATCAGAGAACATATCGAAAAGGCAGAAGTTGCCACACCAATGA
CGATGATGCGTTATTTGAATACTCCTGGAGGAGCAATTTATGGTTTCAAACAAACCTTACAAGATAGTTCCCTATTTCGC
GAATCATTAGATGCCATCGAAGGTCTTTATTCTTCAAGCAGTTGGACAAGCATGGGTGGATTCCAACCGACTTATTTGAA
CGGTTATTACACCGCCCGAAAAATTATCAAACAACTGCGTCGTAAAAACAAAACTGCTGTCTAG

Upstream 100 bases:

>100_bases
GAAACTGGTAAAGCCTTTTCATCACCATGGATGCAGTGAATCGGTAAATCCCTTCCTTCTTTCAGATTTCTTTTTTTAAA
GAGAGGTGGGAAAAAAATCA

Downstream 100 bases:

>100_bases
GTCGTGTGCGACCTCAATCACAGTTGGTAGTAGTGCAAAATATTTTAAATAAGAAAGGAAATACGATATGTTAGATAACA
ACCAAAAATTAGAAACAAAT

Product: putative phytoene dehydrogenase-related protein

Products: NA

Alternate protein names: Phytoene desaturase [H]

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MQSLHCKDWLEWKGNTFGENRMSHYDTVVIGAGNAGLMAATRLQREGSKTLLLERHNVPGGCATSFVRGEFEFEVALHQL
SGVGTESNPFIMRRVFDELGVLDKIELVQEKELYRIIMPGRLDVTLPADWIELQNHLKSLFPMETDPIERFFKLSEAIVN
EYYFVLPRVKLSNDEEKIRIKCPNFSAYGLRPTTDVLNEFFSTEDLINVITPYWSYVGIPTTDLVFAEFIGMIYFYCVYK
PWHIKGGSQMLSSALLSSFEEAGGEVRFHCSAEKILTKDGVVSGVRLETGETVTCDAVVSNASPLITYHELLDLETLPPS
VVKDFKSRRMGVSAVCLYLGLDCSPEEIGFTSASSFVMTTSNAEVTEDRMYTLEAPDWGMVTCYNFIDEELAPKGKSVVT
LVALQYGEAWKDVPPEDYIATKYEFGDKLIDLIEQAYPKIREHIEKAEVATPMTMMRYLNTPGGAIYGFKQTLQDSSLFR
ESLDAIEGLYSSSSWTSMGGFQPTYLNGYYTARKIIKQLRRKNKTAV

Sequences:

>Translated_527_residues
MQSLHCKDWLEWKGNTFGENRMSHYDTVVIGAGNAGLMAATRLQREGSKTLLLERHNVPGGCATSFVRGEFEFEVALHQL
SGVGTESNPFIMRRVFDELGVLDKIELVQEKELYRIIMPGRLDVTLPADWIELQNHLKSLFPMETDPIERFFKLSEAIVN
EYYFVLPRVKLSNDEEKIRIKCPNFSAYGLRPTTDVLNEFFSTEDLINVITPYWSYVGIPTTDLVFAEFIGMIYFYCVYK
PWHIKGGSQMLSSALLSSFEEAGGEVRFHCSAEKILTKDGVVSGVRLETGETVTCDAVVSNASPLITYHELLDLETLPPS
VVKDFKSRRMGVSAVCLYLGLDCSPEEIGFTSASSFVMTTSNAEVTEDRMYTLEAPDWGMVTCYNFIDEELAPKGKSVVT
LVALQYGEAWKDVPPEDYIATKYEFGDKLIDLIEQAYPKIREHIEKAEVATPMTMMRYLNTPGGAIYGFKQTLQDSSLFR
ESLDAIEGLYSSSSWTSMGGFQPTYLNGYYTARKIIKQLRRKNKTAV
>Mature_527_residues
MQSLHCKDWLEWKGNTFGENRMSHYDTVVIGAGNAGLMAATRLQREGSKTLLLERHNVPGGCATSFVRGEFEFEVALHQL
SGVGTESNPFIMRRVFDELGVLDKIELVQEKELYRIIMPGRLDVTLPADWIELQNHLKSLFPMETDPIERFFKLSEAIVN
EYYFVLPRVKLSNDEEKIRIKCPNFSAYGLRPTTDVLNEFFSTEDLINVITPYWSYVGIPTTDLVFAEFIGMIYFYCVYK
PWHIKGGSQMLSSALLSSFEEAGGEVRFHCSAEKILTKDGVVSGVRLETGETVTCDAVVSNASPLITYHELLDLETLPPS
VVKDFKSRRMGVSAVCLYLGLDCSPEEIGFTSASSFVMTTSNAEVTEDRMYTLEAPDWGMVTCYNFIDEELAPKGKSVVT
LVALQYGEAWKDVPPEDYIATKYEFGDKLIDLIEQAYPKIREHIEKAEVATPMTMMRYLNTPGGAIYGFKQTLQDSSLFR
ESLDAIEGLYSSSSWTSMGGFQPTYLNGYYTARKIIKQLRRKNKTAV

Specific function: This enzyme converts phytoene into lycopene via the intermediaries of phytofluene, zeta-carotene and neurosporene by the introduction of four double bonds [H]

COG id: COG1233

COG function: function code Q; Phytoene dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid/retinoid oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI203098013, Length=479, Percent_Identity=23.5908141962422, Blast_Score=96, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR008150
- InterPro:   IPR014105 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: NA

Molecular weight: Translated: 59487; Mature: 59487

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSLHCKDWLEWKGNTFGENRMSHYDTVVIGAGNAGLMAATRLQREGSKTLLLERHNVPG
CCCCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCC
GCATSFVRGEFEFEVALHQLSGVGTESNPFIMRRVFDELGVLDKIELVQEKELYRIIMPG
HHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCEEEECCC
RLDVTLPADWIELQNHLKSLFPMETDPIERFFKLSEAIVNEYYFVLPRVKLSNDEEKIRI
EEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEECCEEECCCCCEEEE
KCPNFSAYGLRPTTDVLNEFFSTEDLINVITPYWSYVGIPTTDLVFAEFIGMIYFYCVYK
ECCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
PWHIKGGSQMLSSALLSSFEEAGGEVRFHCSAEKILTKDGVVSGVRLETGETVTCDAVVS
CEEECCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHCCCCCCCEEECCCCEEEEHHHHC
NASPLITYHELLDLETLPPSVVKDFKSRRMGVSAVCLYLGLDCSPEEIGFTSASSFVMTT
CCCCCEEHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCHHHCCCCCCCCEEEEC
SNAEVTEDRMYTLEAPDWGMVTCYNFIDEELAPKGKSVVTLVALQYGEAWKDVPPEDYIA
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEHHCCHHCCCCCCCCEE
TKYEFGDKLIDLIEQAYPKIREHIEKAEVATPMTMMRYLNTPGGAIYGFKQTLQDSSLFR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHH
ESLDAIEGLYSSSSWTSMGGFQPTYLNGYYTARKIIKQLRRKNKTAV
HHHHHHHHHHCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQSLHCKDWLEWKGNTFGENRMSHYDTVVIGAGNAGLMAATRLQREGSKTLLLERHNVPG
CCCCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCC
GCATSFVRGEFEFEVALHQLSGVGTESNPFIMRRVFDELGVLDKIELVQEKELYRIIMPG
HHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCEEEECCC
RLDVTLPADWIELQNHLKSLFPMETDPIERFFKLSEAIVNEYYFVLPRVKLSNDEEKIRI
EEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEECCEEECCCCCEEEE
KCPNFSAYGLRPTTDVLNEFFSTEDLINVITPYWSYVGIPTTDLVFAEFIGMIYFYCVYK
ECCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
PWHIKGGSQMLSSALLSSFEEAGGEVRFHCSAEKILTKDGVVSGVRLETGETVTCDAVVS
CEEECCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHCCCCCCCEEECCCCEEEEHHHHC
NASPLITYHELLDLETLPPSVVKDFKSRRMGVSAVCLYLGLDCSPEEIGFTSASSFVMTT
CCCCCEEHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCHHHCCCCCCCCEEEEC
SNAEVTEDRMYTLEAPDWGMVTCYNFIDEELAPKGKSVVTLVALQYGEAWKDVPPEDYIA
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEHHCCHHCCCCCCCCEE
TKYEFGDKLIDLIEQAYPKIREHIEKAEVATPMTMMRYLNTPGGAIYGFKQTLQDSSLFR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHH
ESLDAIEGLYSSSSWTSMGGFQPTYLNGYYTARKIIKQLRRKNKTAV
HHHHHHHHHHCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2263648 [H]