Click here to switch to the map view.

The map label for this gene is lip [H]

Identifier: 183220291

GI number: 183220291

Start: 906304

End: 907233

Strand: Reverse

Name: lip [H]

Synonym: LEPBI_I0886

Alternate gene names: 183220291

Gene position: 907233-906304 (Counterclockwise)

Preceding gene: 183220294

Following gene: 183220290

Centisome position: 25.2

GC content: 46.56

Gene sequence:

>930_bases
ATGATTCGAAAAAGTTTTTTGGCCTTATTTGTGACTGCCATGATGGCGTCCCCCATACTTGCGAGTTCTGGCTCTTCTTC
TAAACCACTTGCGGGAACCTACCCGATCATTTTATCCCACGGCTTATTTGGATGGGGTGAAAATTCTGGCGGAATCATTA
GCATTGTCAATTATTGGGGTGGCACTGACGACTACCTAAGAAGCCAAGGAGCAACTGTCTATGCACCTGCAAAAACTGCC
GCCAACTCCAATGAAGTCCGCGCTCAGGAATTAAAAGCAGCCGTCTTAACGTATGCGGCTGCAACAAACTACTCTGGAAA
ATTCCATATCCTTGGTCACTCGCAAGGCGGACTCGATAGCCGATATATGGTCTCTAACCTTGGTCTCTCCACCCGAGTGG
CAACCCTCACAACACTCAACACTCCTCACTACGGATCTCCGATTGCTGACATCATCAAAACGGTCCTTCCCGGATGGATC
CAACCATTTGTGGCAAGCATTGTGGAAACACTTGTAAAGATCGTGTATGGTGGAACCAACCAACAAAATGCACTTGCTGC
CCTTTCTTCGCTCACGAAAGAAGGTTTATCTTCCTTCAATGCATACACTCCTAACCGTTCCGGAGTGAAGTATTACTCGT
ATGGATCTTACATCACTCTTCCTGATTTGATCCAACACCCTCTTATGGGAATTTTACACCCTGCTTGTGCGGCTGGTGGA
CTGTTCCAAGGGCAAGGTGCTACCAATGATGGTCTCGTTCCGCTTTCTTCCCAAAAATGGGGAACTTGGAAAGGTGGCCC
ATCGTATGGAATTTTAACTACGGGTGTGGACCACTTACAAGTATCGAACACACTTCGTTCTGGAAGTTTCTGGTATGATG
TGGAAGGATTTTATATGAAGATGGCTTCCAACATGAAAGCGAACCAATAA

Upstream 100 bases:

>100_bases
TATTTTTGCCATTTTTTTATTTGTCATAAAAAAATTTCCTTGCCTCATATAAGTCAAATTGACACAATTTTATCTTAGAA
AATTCAGAGGTGAAATATAT

Downstream 100 bases:

>100_bases
TCCAATTCTGAAGTTTTTTTAGAAAACCCAAGCAATTGCTTGGGTTTTTTTGTATCCAGAAATAATTTTTCATCGTTCAC
TACACTACAATCTCCATGAA

Product: triacylglycerol lipase

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MIRKSFLALFVTAMMASPILASSGSSSKPLAGTYPIILSHGLFGWGENSGGIISIVNYWGGTDDYLRSQGATVYAPAKTA
ANSNEVRAQELKAAVLTYAAATNYSGKFHILGHSQGGLDSRYMVSNLGLSTRVATLTTLNTPHYGSPIADIIKTVLPGWI
QPFVASIVETLVKIVYGGTNQQNALAALSSLTKEGLSSFNAYTPNRSGVKYYSYGSYITLPDLIQHPLMGILHPACAAGG
LFQGQGATNDGLVPLSSQKWGTWKGGPSYGILTTGVDHLQVSNTLRSGSFWYDVEGFYMKMASNMKANQ

Sequences:

>Translated_309_residues
MIRKSFLALFVTAMMASPILASSGSSSKPLAGTYPIILSHGLFGWGENSGGIISIVNYWGGTDDYLRSQGATVYAPAKTA
ANSNEVRAQELKAAVLTYAAATNYSGKFHILGHSQGGLDSRYMVSNLGLSTRVATLTTLNTPHYGSPIADIIKTVLPGWI
QPFVASIVETLVKIVYGGTNQQNALAALSSLTKEGLSSFNAYTPNRSGVKYYSYGSYITLPDLIQHPLMGILHPACAAGG
LFQGQGATNDGLVPLSSQKWGTWKGGPSYGILTTGVDHLQVSNTLRSGSFWYDVEGFYMKMASNMKANQ
>Mature_309_residues
MIRKSFLALFVTAMMASPILASSGSSSKPLAGTYPIILSHGLFGWGENSGGIISIVNYWGGTDDYLRSQGATVYAPAKTA
ANSNEVRAQELKAAVLTYAAATNYSGKFHILGHSQGGLDSRYMVSNLGLSTRVATLTTLNTPHYGSPIADIIKTVLPGWI
QPFVASIVETLVKIVYGGTNQQNALAALSSLTKEGLSSFNAYTPNRSGVKYYSYGSYITLPDLIQHPLMGILHPACAAGG
LFQGQGATNDGLVPLSSQKWGTWKGGPSYGILTTGVDHLQVSNTLRSGSFWYDVEGFYMKMASNMKANQ

Specific function: Catalyzes the hydrolysis of triglycerides. Catalyzes the synthesis of macrocyclic lactones in anhydrous organic solvents [H]

COG id: COG1075

COG function: function code R; Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold

Gene ontology:

Cell location: Cell surface. Secreted, extracellular space. Note=During early stationary growth phase about 10% of the enzyme molecules remain cell-bound while about 90% are released into the growth medium [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Pseudomonas lipase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320263, Length=269, Percent_Identity=27.8810408921933, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 32898; Mature: 32898

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRKSFLALFVTAMMASPILASSGSSSKPLAGTYPIILSHGLFGWGENSGGIISIVNYWG
CCHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCEEEEEECCC
GTDDYLRSQGATVYAPAKTAANSNEVRAQELKAAVLTYAAATNYSGKFHILGHSQGGLDS
CCHHHHHCCCCEEEECCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
RYMVSNLGLSTRVATLTTLNTPHYGSPIADIIKTVLPGWIQPFVASIVETLVKIVYGGTN
HHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
QQNALAALSSLTKEGLSSFNAYTPNRSGVKYYSYGSYITLPDLIQHPLMGILHPACAAGG
CHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEECHHHHHHHHHHHHHHHHHCCC
LFQGQGATNDGLVPLSSQKWGTWKGGPSYGILTTGVDHLQVSNTLRSGSFWYDVEGFYMK
CEECCCCCCCCEEECCCCCCCCCCCCCCCCEEECCCHHHHHHHHHCCCCEEEECHHHHHH
MASNMKANQ
HHHCCCCCC
>Mature Secondary Structure
MIRKSFLALFVTAMMASPILASSGSSSKPLAGTYPIILSHGLFGWGENSGGIISIVNYWG
CCHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCEEEEEECCC
GTDDYLRSQGATVYAPAKTAANSNEVRAQELKAAVLTYAAATNYSGKFHILGHSQGGLDS
CCHHHHHCCCCEEEECCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
RYMVSNLGLSTRVATLTTLNTPHYGSPIADIIKTVLPGWIQPFVASIVETLVKIVYGGTN
HHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
QQNALAALSSLTKEGLSSFNAYTPNRSGVKYYSYGSYITLPDLIQHPLMGILHPACAAGG
CHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEECHHHHHHHHHHHHHHHHHCCC
LFQGQGATNDGLVPLSSQKWGTWKGGPSYGILTTGVDHLQVSNTLRSGSFWYDVEGFYMK
CEECCCCCCCCEEECCCCCCCCCCCCCCCCEEECCCHHHHHHHHHCCCCEEEECHHHHHH
MASNMKANQ
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1512563; 1632642; 1576157; 10984043; 1748875; 11133953 [H]