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The map label for this gene is lntA [H]

Identifier: 183220289

GI number: 183220289

Start: 903568

End: 905115

Strand: Reverse

Name: lntA [H]

Synonym: LEPBI_I0884

Alternate gene names: 183220289

Gene position: 905115-903568 (Counterclockwise)

Preceding gene: 183220290

Following gene: 183220288

Centisome position: 25.14

GC content: 39.15

Gene sequence:

>1548_bases
TTGTCCCTCGAACCCTTCGGTTTTGCCACCGCTGGGTTTTTCTGTTTATTTTTCCTTTTACTCATTACAAAAGAAATCAG
AAACGAAGGACAACTAAGGAGTGCTCTCCTTTATACAGTTCTATTTTCCTTTTTAGTGACTTGCACATCCTTTTATTGGA
TGGGAAAAGCCATCGCAAACATCACGGGTCATGGATACTTTTTTTCGGCATTACTCTTTTTGATCTATGGATTTTTATCA
TTTTATAAAATTGGAATCGTATTCATTGGATCTCATCTCGTCACCAAATACCGATTTGTCTCTGATACAAAATTTTTTCT
ATTTTGTTTCCCATCTCTTTTCCTATTATCGGATGCGATTTGTCCGATGGTATTTCCTGTCTATTGGGGTGATCTCTTTC
GGAACCAACTCCTTTGGCGCCAAATCGCACGACTTGGGACCGAAGTGTTGGGCTTTGTCTCTGTCATTTCTGTGGCCTTA
ATGTATTTAATGGTAATCAAAAAAGAATACGAATGGAAAAGGTCCTTTCCATACCTGGTTCCCATCTTTTTTATTTTTTG
TACGAACTTATACTTTTTAGCAGAATCGATCCCACAAGAAAAGAACATCCACCTTGTTTTGCTACAGCCAAACACACCAT
ATGCGAAAAATGAAATCCGAGAAGATTTTGTGTTTATGACAAAAACCATCCAAGAAGTTTACAATCTAGGGGAAGAAGCC
ATACGAAATGCCCCTAAACCAATCGATGCCATCCTCTTACCTGAATCATCGATTCCATTTTTAGGAACTTTGCCTTCGTC
TCATCCGAGTTCCACTTATAGTAAAAGTTTTGTGGATATCACAGAAAAATTGGTTTCTCTTTCGAATGCACCCTTACTTT
TTAACGAACTTGTTTGGGATGATGGTTCCAGAAATTCGTTTAGCCAGTTATCGCCTGTTACATTAAAAACAGAAAGGCGA
TACAAACATATTCTTTTGCCTTTTGGTGAGTATCTTCCCTTTGAAACTGTATTTCCTTTTTTAAGGACTCTTTTCCAAGA
GGTAAGCCATCATAACCCAAATCTAAAATTTGATTCCCAATCGATCCAAACCAAATCCGGAGAATCCATAGAGTTCACTC
CTCTTATCTGTTATGAAGTTTTGTACCCAGACTTTGTCCGAGAGATGGTACTCCATTCCCCATCAGAGCTTCTCATCAAT
CTTACAAACGACTCATGGTTTGAAAGCCATACGGAAACCAAACAACATGCAGGAGCTGGAAGGTTACGAGCCATTGAAAC
AGGGAGACCTTACATCCGAGCTGCCGTTTCAGGGATGACCACGGCTTATGATCCATGGGGGCGGGAGATGATGGGGGAAC
TTCCTATCTTTCAAAAAGCCATCGGATATTTGGATGTCCTCACTGTTGCCAAAGAGCGAGAAACCCCTTATTTAAAGTTT
GGACCATATCCTTGGAGATTATTGGCTGTTTTGAGCTTATTTTTTGTATTTTTCATGAGTCCAAAGGCTTTCGACTCTCA
TAAAAAGAAAAATGAAATTGAAATTTAG

Upstream 100 bases:

>100_bases
GAAGAATACACTCGACGATTGGAATATGAAAAAACACTTAAAAATTCCGGGAATTGATTCACCGTATGTATATCTAATTC
TTTCTGCAATTTGTTTTGCA

Downstream 100 bases:

>100_bases
CATAGGATAGAAAGGCTATTCGAATATGGAATGGGAAAAAATACTTCGCGATGCAGTCAAAGAAAACTCGATTAAGGAGT
TGTATCTGAGAAAGGTACCA

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase 1 [H]

Number of amino acids: Translated: 515; Mature: 514

Protein sequence:

>515_residues
MSLEPFGFATAGFFCLFFLLLITKEIRNEGQLRSALLYTVLFSFLVTCTSFYWMGKAIANITGHGYFFSALLFLIYGFLS
FYKIGIVFIGSHLVTKYRFVSDTKFFLFCFPSLFLLSDAICPMVFPVYWGDLFRNQLLWRQIARLGTEVLGFVSVISVAL
MYLMVIKKEYEWKRSFPYLVPIFFIFCTNLYFLAESIPQEKNIHLVLLQPNTPYAKNEIREDFVFMTKTIQEVYNLGEEA
IRNAPKPIDAILLPESSIPFLGTLPSSHPSSTYSKSFVDITEKLVSLSNAPLLFNELVWDDGSRNSFSQLSPVTLKTERR
YKHILLPFGEYLPFETVFPFLRTLFQEVSHHNPNLKFDSQSIQTKSGESIEFTPLICYEVLYPDFVREMVLHSPSELLIN
LTNDSWFESHTETKQHAGAGRLRAIETGRPYIRAAVSGMTTAYDPWGREMMGELPIFQKAIGYLDVLTVAKERETPYLKF
GPYPWRLLAVLSLFFVFFMSPKAFDSHKKKNEIEI

Sequences:

>Translated_515_residues
MSLEPFGFATAGFFCLFFLLLITKEIRNEGQLRSALLYTVLFSFLVTCTSFYWMGKAIANITGHGYFFSALLFLIYGFLS
FYKIGIVFIGSHLVTKYRFVSDTKFFLFCFPSLFLLSDAICPMVFPVYWGDLFRNQLLWRQIARLGTEVLGFVSVISVAL
MYLMVIKKEYEWKRSFPYLVPIFFIFCTNLYFLAESIPQEKNIHLVLLQPNTPYAKNEIREDFVFMTKTIQEVYNLGEEA
IRNAPKPIDAILLPESSIPFLGTLPSSHPSSTYSKSFVDITEKLVSLSNAPLLFNELVWDDGSRNSFSQLSPVTLKTERR
YKHILLPFGEYLPFETVFPFLRTLFQEVSHHNPNLKFDSQSIQTKSGESIEFTPLICYEVLYPDFVREMVLHSPSELLIN
LTNDSWFESHTETKQHAGAGRLRAIETGRPYIRAAVSGMTTAYDPWGREMMGELPIFQKAIGYLDVLTVAKERETPYLKF
GPYPWRLLAVLSLFFVFFMSPKAFDSHKKKNEIEI
>Mature_514_residues
SLEPFGFATAGFFCLFFLLLITKEIRNEGQLRSALLYTVLFSFLVTCTSFYWMGKAIANITGHGYFFSALLFLIYGFLSF
YKIGIVFIGSHLVTKYRFVSDTKFFLFCFPSLFLLSDAICPMVFPVYWGDLFRNQLLWRQIARLGTEVLGFVSVISVALM
YLMVIKKEYEWKRSFPYLVPIFFIFCTNLYFLAESIPQEKNIHLVLLQPNTPYAKNEIREDFVFMTKTIQEVYNLGEEAI
RNAPKPIDAILLPESSIPFLGTLPSSHPSSTYSKSFVDITEKLVSLSNAPLLFNELVWDDGSRNSFSQLSPVTLKTERRY
KHILLPFGEYLPFETVFPFLRTLFQEVSHHNPNLKFDSQSIQTKSGESIEFTPLICYEVLYPDFVREMVLHSPSELLINL
TNDSWFESHTETKQHAGAGRLRAIETGRPYIRAAVSGMTTAYDPWGREMMGELPIFQKAIGYLDVLTVAKERETPYLKFG
PYPWRLLAVLSLFFVFFMSPKAFDSHKKKNEIEI

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=372, Percent_Identity=25.2688172043011, Blast_Score=92, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 59423; Mature: 59292

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
>Mature Secondary Structure 
SLEPFGFATAGFFCLFFLLLITKEIRNEGQLRSALLYTVLFSFLVTCTSFYWMGKAIAN
CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH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CCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA