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The map label for this gene is rsbU [H]

Identifier: 183219983

GI number: 183219983

Start: 563230

End: 565191

Strand: Reverse

Name: rsbU [H]

Synonym: LEPBI_I0565

Alternate gene names: 183219983

Gene position: 565191-563230 (Counterclockwise)

Preceding gene: 183219985

Following gene: 183219982

Centisome position: 15.7

GC content: 36.24

Gene sequence:

>1962_bases
GTGAAAAAAGAAATCGTGTATCCTGGTCCCTGGATGAACGAGGAATCGGAATTTGAACGAATCTGCCTTCTTTGTACTGA
ACCTCGTGTTCCCAGTGGCATCACGAAAGCAGGTCGATTTTTCTGCCAAACCTGCCAGAGGGAATGGATCTTAGAAAAAC
GAAAAATCCCTCGAGTGGGCAAACATGTCCTCAATTCAGATGAAAAAACAGAATTCCTATTAGAGAACTTATCCCTATTT
AACTCCTCACTTGGTTTAGATGATTTGATGTTTCGTTTTAGCGAACTCATCTCTGATCGCTTAAAAAAAGATAAAATTGC
AATTTTTATAACAAACCTAGAGTTAGGTGAAATAAAATTAGCTCATTATTACACCAAACAAAAACATTTGCAAAGAGTCA
TCAAACGAATCACTCTCGATTATGATTTGAGTTACGGAATTTTAATAGAAGCGATGGCGAAGAGAGAGCCTTGTTTTTAT
AAATTCAGTGACCAAACCCATCCGTTTTATTCCTTTTATTCAAAACTTACTGGCACCAAATCTCAATTGGTCTTACCTAT
ATTGTATGCAAACATCGCTGTTGGAATGATCACAATCGATTATGAAGACGAAGACACATTGGATTATATTGAAGATGAAG
AAATTCTCAAAATTGTTGTCGGACAATTTGCCGTTTCACTTAGAAATTCGCTTCTGTTTTCCAAATCAAAAAATCAATCG
AAACACTTTAGAAGTTTACATACGGCTGCATTAACATTAAGCCAACTCTATCTAAACAATCACAATGAGATGATTCGAAT
GATTCTACTCACATTATCAGGAATTGTAGACTCATCCATTTCTTGTTTGGTAGAAATTCCTCCAAACGTTACCAAAGCAA
AAGTATTCAAAGTATACCGAGATCTGGAAAATTATGAACTTAAAACATTGACTGACTCAGTGGATATCAATGATCTAAAT
TTTATACTCCAAACAAAAGAAATTTTGGCAGTTGATCCTTCTATAGATGTTATCTTTCAAACACTTGGAATCACTGGAAA
AGAAACACTCATCGTACCCGTAAAATTAGAAAACGAAACTATTTGTATTTTTATTTTGGCCAAAGAAGAAACTCGATTCC
CGCATGAAGAAATTGAAGCTCTGAATGCTTTCGTTTCACTCGCAAGAATCACCATGGAAAATTCCAATTTATACCAAAAT
CTTTCAAACAAAGAAAGATTGGAGAAAGAAATTGAAATTGCTAAAGAAATTCAAAGTAATCTTTTACCTCGTAACGCACC
AGAAGCGGATGGATTTTCCTTTGGTGGACTCATGGTACCTGCTCGAGGGATCGGAGGTGATTATTATGATTTTATATTAT
CACCGAATCGAAATGAGTTATTTGTCTGCATTGGTGATGTCAGTGGAAAAGGAGTCGCAGCAGGTCTTGTAATGGCTACC
GTTAGAACCATCCTCCATTCTCTCGTTCGAGTAAAAGATTCCCCCTGGGAAATTTTAAACGATATCAACAATTACTTATA
TTCCAGTTATCGAGATGCGATCACTCCACGATTTATGAGTATGATCTTGATTCGTTGGAATTTGATTTCCGATGAAGTGG
AAGTATCGGGAGCTGGGCATGGAAATTTTTACCATTACCAATTATACTCCAACACAGTTAGATCCATTGAAACTGGTGGT
GTCATCTTGGGAATCAGTCCCGACATATCCAAATTTAAAAATGAAACTAAATTGTATTTCAAGGCTGGGGATACAATCCT
ACTCTATACAGACGGTGTAACAGAAGCTCTCAATGCTTACGAAAAACAATACGGCGAACTTAGTTTAGAGGAGAGTTTCC
GAAATCACATCCTTTTGGAACCAAAAAAGATTTTAGAGAATATTTATTTGGATCTAAAAGAATTTGTCAAGGAACAGGAA
CAACACGATGATATCACAATGGTGGCCGTGAGGAAAATATGA

Upstream 100 bases:

>100_bases
TTGCCTTCCTTTCGATTTCAGCAGAAAAAACAACATTTGCTTATAGATTAAGCATGAATCGTACCAGGTTTCTTCCCTCG
GAAGGAAATTCTTGTAGCTT

Downstream 100 bases:

>100_bases
TTCCAAAAATCCCTGATTCTGTTTCCATCCATTTTGAATCTATGCTCAAAAGAATGGGAAACCAACTGCCAAACGAATGG
ATCAAAAACAAAACAAAATT

Product: putative phosphoserine phosphatase RsbU

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 653; Mature: 653

Protein sequence:

>653_residues
MKKEIVYPGPWMNEESEFERICLLCTEPRVPSGITKAGRFFCQTCQREWILEKRKIPRVGKHVLNSDEKTEFLLENLSLF
NSSLGLDDLMFRFSELISDRLKKDKIAIFITNLELGEIKLAHYYTKQKHLQRVIKRITLDYDLSYGILIEAMAKREPCFY
KFSDQTHPFYSFYSKLTGTKSQLVLPILYANIAVGMITIDYEDEDTLDYIEDEEILKIVVGQFAVSLRNSLLFSKSKNQS
KHFRSLHTAALTLSQLYLNNHNEMIRMILLTLSGIVDSSISCLVEIPPNVTKAKVFKVYRDLENYELKTLTDSVDINDLN
FILQTKEILAVDPSIDVIFQTLGITGKETLIVPVKLENETICIFILAKEETRFPHEEIEALNAFVSLARITMENSNLYQN
LSNKERLEKEIEIAKEIQSNLLPRNAPEADGFSFGGLMVPARGIGGDYYDFILSPNRNELFVCIGDVSGKGVAAGLVMAT
VRTILHSLVRVKDSPWEILNDINNYLYSSYRDAITPRFMSMILIRWNLISDEVEVSGAGHGNFYHYQLYSNTVRSIETGG
VILGISPDISKFKNETKLYFKAGDTILLYTDGVTEALNAYEKQYGELSLEESFRNHILLEPKKILENIYLDLKEFVKEQE
QHDDITMVAVRKI

Sequences:

>Translated_653_residues
MKKEIVYPGPWMNEESEFERICLLCTEPRVPSGITKAGRFFCQTCQREWILEKRKIPRVGKHVLNSDEKTEFLLENLSLF
NSSLGLDDLMFRFSELISDRLKKDKIAIFITNLELGEIKLAHYYTKQKHLQRVIKRITLDYDLSYGILIEAMAKREPCFY
KFSDQTHPFYSFYSKLTGTKSQLVLPILYANIAVGMITIDYEDEDTLDYIEDEEILKIVVGQFAVSLRNSLLFSKSKNQS
KHFRSLHTAALTLSQLYLNNHNEMIRMILLTLSGIVDSSISCLVEIPPNVTKAKVFKVYRDLENYELKTLTDSVDINDLN
FILQTKEILAVDPSIDVIFQTLGITGKETLIVPVKLENETICIFILAKEETRFPHEEIEALNAFVSLARITMENSNLYQN
LSNKERLEKEIEIAKEIQSNLLPRNAPEADGFSFGGLMVPARGIGGDYYDFILSPNRNELFVCIGDVSGKGVAAGLVMAT
VRTILHSLVRVKDSPWEILNDINNYLYSSYRDAITPRFMSMILIRWNLISDEVEVSGAGHGNFYHYQLYSNTVRSIETGG
VILGISPDISKFKNETKLYFKAGDTILLYTDGVTEALNAYEKQYGELSLEESFRNHILLEPKKILENIYLDLKEFVKEQE
QHDDITMVAVRKI
>Mature_653_residues
MKKEIVYPGPWMNEESEFERICLLCTEPRVPSGITKAGRFFCQTCQREWILEKRKIPRVGKHVLNSDEKTEFLLENLSLF
NSSLGLDDLMFRFSELISDRLKKDKIAIFITNLELGEIKLAHYYTKQKHLQRVIKRITLDYDLSYGILIEAMAKREPCFY
KFSDQTHPFYSFYSKLTGTKSQLVLPILYANIAVGMITIDYEDEDTLDYIEDEEILKIVVGQFAVSLRNSLLFSKSKNQS
KHFRSLHTAALTLSQLYLNNHNEMIRMILLTLSGIVDSSISCLVEIPPNVTKAKVFKVYRDLENYELKTLTDSVDINDLN
FILQTKEILAVDPSIDVIFQTLGITGKETLIVPVKLENETICIFILAKEETRFPHEEIEALNAFVSLARITMENSNLYQN
LSNKERLEKEIEIAKEIQSNLLPRNAPEADGFSFGGLMVPARGIGGDYYDFILSPNRNELFVCIGDVSGKGVAAGLVMAT
VRTILHSLVRVKDSPWEILNDINNYLYSSYRDAITPRFMSMILIRWNLISDEVEVSGAGHGNFYHYQLYSNTVRSIETGG
VILGISPDISKFKNETKLYFKAGDTILLYTDGVTEALNAYEKQYGELSLEESFRNHILLEPKKILENIYLDLKEFVKEQE
QHDDITMVAVRKI

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 74818; Mature: 74818

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEIVYPGPWMNEESEFERICLLCTEPRVPSGITKAGRFFCQTCQREWILEKRKIPRVG
CCCCEECCCCCCCCCHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
KHVLNSDEKTEFLLENLSLFNSSLGLDDLMFRFSELISDRLKKDKIAIFITNLELGEIKL
HHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEH
AHYYTKQKHLQRVIKRITLDYDLSYGILIEAMAKREPCFYKFSDQTHPFYSFYSKLTGTK
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCC
SQLVLPILYANIAVGMITIDYEDEDTLDYIEDEEILKIVVGQFAVSLRNSLLFSKSKNQS
HHHHHHHHHHHHEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
KHFRSLHTAALTLSQLYLNNHNEMIRMILLTLSGIVDSSISCLVEIPPNVTKAKVFKVYR
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHH
DLENYELKTLTDSVDINDLNFILQTKEILAVDPSIDVIFQTLGITGKETLIVPVKLENET
HHCCCEEEEECCCCCCCCHHEEEEECEEEEECCCHHHHHHHHCCCCCCEEEEEEEECCCE
ICIFILAKEETRFPHEEIEALNAFVSLARITMENSNLYQNLSNKERLEKEIEIAKEIQSN
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHC
LLPRNAPEADGFSFGGLMVPARGIGGDYYDFILSPNRNELFVCIGDVSGKGVAAGLVMAT
CCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHH
VRTILHSLVRVKDSPWEILNDINNYLYSSYRDAITPRFMSMILIRWNLISDEVEVSGAGH
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEECCCCC
GNFYHYQLYSNTVRSIETGGVILGISPDISKFKNETKLYFKAGDTILLYTDGVTEALNAY
CCEEEEEEEHHHHHHCCCCCEEEEECCCHHHHCCCCEEEEEECCEEEEEECCHHHHHHHH
EKQYGELSLEESFRNHILLEPKKILENIYLDLKEFVKEQEQHDDITMVAVRKI
HHHHCCCCHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
>Mature Secondary Structure
MKKEIVYPGPWMNEESEFERICLLCTEPRVPSGITKAGRFFCQTCQREWILEKRKIPRVG
CCCCEECCCCCCCCCHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
KHVLNSDEKTEFLLENLSLFNSSLGLDDLMFRFSELISDRLKKDKIAIFITNLELGEIKL
HHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEH
AHYYTKQKHLQRVIKRITLDYDLSYGILIEAMAKREPCFYKFSDQTHPFYSFYSKLTGTK
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCC
SQLVLPILYANIAVGMITIDYEDEDTLDYIEDEEILKIVVGQFAVSLRNSLLFSKSKNQS
HHHHHHHHHHHHEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
KHFRSLHTAALTLSQLYLNNHNEMIRMILLTLSGIVDSSISCLVEIPPNVTKAKVFKVYR
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHH
DLENYELKTLTDSVDINDLNFILQTKEILAVDPSIDVIFQTLGITGKETLIVPVKLENET
HHCCCEEEEECCCCCCCCHHEEEEECEEEEECCCHHHHHHHHCCCCCCEEEEEEEECCCE
ICIFILAKEETRFPHEEIEALNAFVSLARITMENSNLYQNLSNKERLEKEIEIAKEIQSN
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHC
LLPRNAPEADGFSFGGLMVPARGIGGDYYDFILSPNRNELFVCIGDVSGKGVAAGLVMAT
CCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHH
VRTILHSLVRVKDSPWEILNDINNYLYSSYRDAITPRFMSMILIRWNLISDEVEVSGAGH
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEECCCCC
GNFYHYQLYSNTVRSIETGGVILGISPDISKFKNETKLYFKAGDTILLYTDGVTEALNAY
CCEEEEEEEHHHHHHCCCCCEEEEECCCHHHHCCCCEEEEEECCEEEEEECCHHHHHHHH
EKQYGELSLEESFRNHILLEPKKILENIYLDLKEFVKEQEQHDDITMVAVRKI
HHHHCCCCHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]