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The map label for this gene is exbB1 [H]

Identifier: 183219574

GI number: 183219574

Start: 143725

End: 144564

Strand: Reverse

Name: exbB1 [H]

Synonym: LEPBI_I0149

Alternate gene names: 183219574

Gene position: 144564-143725 (Counterclockwise)

Preceding gene: 183219575

Following gene: 183219573

Centisome position: 4.02

GC content: 42.98

Gene sequence:

>840_bases
ATGAACGTTTCATGTAACCTGGCAAAGAAAAACATCACTTTGTCTGTTGTGATCGCACTCATCACAATTTTTACAATTGC
AGGTAGAATCGAAGCACAATCTACCCCAACAACAACTAGCACAGATACTACGCAAAACACAGAAGCACCAGCTGAAACTC
CTGCACCTGCCGCTGAAGCACCACAAGAATCCGCTCCGCAAGAATCGGAAATCGGGCTCGTTAAATTATTTGTGACTGGT
GGATGGTCCATGTGGCCACTCCTACTCGCTTCCATCGTTGGATTTGGAGTGATTCTCGAAAGGATGTACTTTTTTTTCAC
AGCAAAGCTTGTGAGAAAAGGTTACAACCAAGATTTACAAGATGCGATTGATGCTTCTGGTATGCAAGGTGTAGACGAAT
TCCTAAAAGCGAATGAAGGACAACGAATCACTGATGTCTTAAAAAATGGAATGGAAGTTTCCCAAAACGACCCTGAAATT
TTTGCCGCTGGTATCGAAAGAGAAGCGGGTGAAGTCATGACTCTCTTAGAAAAAGGACTCACTGTTCTTTCAGCAGTTTC
CACAATTGCTCCACTCGTTGGATTCCTTGGAACCGTATCTGGTATGATCAACGCTTTTGATGCGATTGCAAACGCTGACC
AAGTAAACGCAAAAGTGGTCGCAGGTGGTATCAAAGAAGCCCTTATCACTACAGCAGCTGGTCTGATCGTTGCGATCCCT
GCGATGACATTCTACCAATACTTACAAGGCCGAGTTGGTTTTTTTACTTCTGAAGTAGAAGAAGCAGCAAACAAAATCTA
CAAAGAATACTTAAAACTCAAAGCCGGAAAAAAAGCGTAA

Upstream 100 bases:

>100_bases
TTTTTGACAGCTTAATTACTCTCTTTGTCATCCATCTGTCATCTAAATGTAACAGAGATCCACTAGATTTGAAACATATC
AATTAGATATGGAGACATTC

Downstream 100 bases:

>100_bases
AGCAAACGGTAAGTAACGAACCATGATCAAGTTAAAGAAAAAACAAGAAATAGAGGAAATTTCGGCAGCATCCATGTCGG
ACATTGCCTTTCTACTCTTG

Product: biopolymer transport ExbB protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MNVSCNLAKKNITLSVVIALITIFTIAGRIEAQSTPTTTSTDTTQNTEAPAETPAPAAEAPQESAPQESEIGLVKLFVTG
GWSMWPLLLASIVGFGVILERMYFFFTAKLVRKGYNQDLQDAIDASGMQGVDEFLKANEGQRITDVLKNGMEVSQNDPEI
FAAGIEREAGEVMTLLEKGLTVLSAVSTIAPLVGFLGTVSGMINAFDAIANADQVNAKVVAGGIKEALITTAAGLIVAIP
AMTFYQYLQGRVGFFTSEVEEAANKIYKEYLKLKAGKKA

Sequences:

>Translated_279_residues
MNVSCNLAKKNITLSVVIALITIFTIAGRIEAQSTPTTTSTDTTQNTEAPAETPAPAAEAPQESAPQESEIGLVKLFVTG
GWSMWPLLLASIVGFGVILERMYFFFTAKLVRKGYNQDLQDAIDASGMQGVDEFLKANEGQRITDVLKNGMEVSQNDPEI
FAAGIEREAGEVMTLLEKGLTVLSAVSTIAPLVGFLGTVSGMINAFDAIANADQVNAKVVAGGIKEALITTAAGLIVAIP
AMTFYQYLQGRVGFFTSEVEEAANKIYKEYLKLKAGKKA
>Mature_279_residues
MNVSCNLAKKNITLSVVIALITIFTIAGRIEAQSTPTTTSTDTTQNTEAPAETPAPAAEAPQESAPQESEIGLVKLFVTG
GWSMWPLLLASIVGFGVILERMYFFFTAKLVRKGYNQDLQDAIDASGMQGVDEFLKANEGQRITDVLKNGMEVSQNDPEI
FAAGIEREAGEVMTLLEKGLTVLSAVSTIAPLVGFLGTVSGMINAFDAIANADQVNAKVVAGGIKEALITTAAGLIVAIP
AMTFYQYLQGRVGFFTSEVEEAANKIYKEYLKLKAGKKA

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=190, Percent_Identity=29.4736842105263, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1786958, Length=77, Percent_Identity=45.4545454545455, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014164 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 29738; Mature: 29738

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVSCNLAKKNITLSVVIALITIFTIAGRIEAQSTPTTTSTDTTQNTEAPAETPAPAAEA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PQESAPQESEIGLVKLFVTGGWSMWPLLLASIVGFGVILERMYFFFTAKLVRKGYNQDLQ
CCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
DAIDASGMQGVDEFLKANEGQRITDVLKNGMEVSQNDPEIFAAGIEREAGEVMTLLEKGL
HHHHCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHH
TVLSAVSTIAPLVGFLGTVSGMINAFDAIANADQVNAKVVAGGIKEALITTAAGLIVAIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AMTFYQYLQGRVGFFTSEVEEAANKIYKEYLKLKAGKKA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNVSCNLAKKNITLSVVIALITIFTIAGRIEAQSTPTTTSTDTTQNTEAPAETPAPAAEA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PQESAPQESEIGLVKLFVTGGWSMWPLLLASIVGFGVILERMYFFFTAKLVRKGYNQDLQ
CCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
DAIDASGMQGVDEFLKANEGQRITDVLKNGMEVSQNDPEIFAAGIEREAGEVMTLLEKGL
HHHHCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHH
TVLSAVSTIAPLVGFLGTVSGMINAFDAIANADQVNAKVVAGGIKEALITTAAGLIVAIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AMTFYQYLQGRVGFFTSEVEEAANKIYKEYLKLKAGKKA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]