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The map label for this gene is ygcA [C]

Identifier: 183219518

GI number: 183219518

Start: 91365

End: 92564

Strand: Reverse

Name: ygcA [C]

Synonym: LEPBI_I0091

Alternate gene names: 183219518

Gene position: 92564-91365 (Counterclockwise)

Preceding gene: 183219519

Following gene: 183219514

Centisome position: 2.57

GC content: 40.75

Gene sequence:

>1200_bases
ATGACGACAACAAAAACTGGCAATTCGATCTGTACCCACTTTGGCACTTGTGGTGGATGTAATTATCTCGACATTGATTA
TACGAAAGAACTTCGCAAAAAAGAGCAAAACATCAAAGAACTCTTTAAAGCATATCGACATGTTGAAATTAAAACCATTG
TTCCCAGTCCCTCACCCGAATACTACCGTCACAAAATCCAACTTCCTTTTGGCCGAAGGATTGTCGGGAACAAAACCTTA
CTCACCCTAGGACTTTTCAATAAAGAAGCTTCCTTTGTCCTAGACCAAACGGAATGCCAAATCCAAGACCCAGGTCTTAC
GGAAGTGGCCCTTGCCGTCAAACAATGGGCAAGAAGAGAAGGATTATTGCCCTATAATGAAAAATCAAAACGGGGTATGA
TGAAATATCTTGTCGCAAGGAAATCCATCACCACAGGTGAAATCATTGTAGGAATTGTGACGGCTAAAGAAGACCTTCCG
CATGCAAAGGATGCATCCAAACGGTTACACACTGCCATCCAAAATCGGATCGGAAAAACAGGTAAGTTTGGAAAACTCGT
CGGTATCATTCATAACATCAATACCAAACACACAACCATGGCACTTGGTCGCGAAGAACATCTGTTATGGGGTAGACCCT
ACATCCACGAACATTTTGGAAAACACAAATTCCGTGTTGGACTTTCCACCTTTTTACAAGTAAACCCCATCCAAACCCCC
AGTTTGTACAATTTAGTATTGGATGAAATTGAGAAGGATTCCCGTGTCATTGATGCTTATTCGGGAATTGGTACCATTTC
GTTTTGGATTGCGGGACAAAGTAAAGAAGTCCTTGGGATTGAGGAAAATCCAAATTCTCATAGAACGGCTCTGGAATCAT
TAAAATACAACAAAGTACATAATGTTCGATTTCGGAAAGGAAGGGTGGCAGAAGTGTTACCTACTCTTTATGGAAAAAAT
TACGATACAATTGTTCTCGACCCACCAAGGACTGGCCTTGGGGCCGAAGTGACAGAAACCATTTTGGCAATGGGGTTCAA
AAAAATTGTGTATGTCTCTTGTGATCCAATGAGCCTACGAGAAGATTCCATTTTACTCACAAAACAATATTTTTTAAATT
CCTTACAACCTGTGGATATGTTTCCAAGAACCGATCACGTAGAAACGGTCGCGGTGTTTCGAAATAAAAATCTCATATAA

Upstream 100 bases:

>100_bases
GTCCGTTTTTGCCGTATCAAATTTGTTCTTACCTAGACAAAGTGGTGAAAGATCGAGGATACCAAACGATCAGCGAACTG
GTAGGCTCGGGGAATTCAAA

Downstream 100 bases:

>100_bases
CCTCAGCAACAAACTCGGATGCTTTTTTACTAAATGCCATAATGGTAAAACTTGGATCCACACTGACTCCTGTTGGAAAA
ACAGACGAATCGGCCACAAA

Product: putative tRNA (uracil-5-)-methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MTTTKTGNSICTHFGTCGGCNYLDIDYTKELRKKEQNIKELFKAYRHVEIKTIVPSPSPEYYRHKIQLPFGRRIVGNKTL
LTLGLFNKEASFVLDQTECQIQDPGLTEVALAVKQWARREGLLPYNEKSKRGMMKYLVARKSITTGEIIVGIVTAKEDLP
HAKDASKRLHTAIQNRIGKTGKFGKLVGIIHNINTKHTTMALGREEHLLWGRPYIHEHFGKHKFRVGLSTFLQVNPIQTP
SLYNLVLDEIEKDSRVIDAYSGIGTISFWIAGQSKEVLGIEENPNSHRTALESLKYNKVHNVRFRKGRVAEVLPTLYGKN
YDTIVLDPPRTGLGAEVTETILAMGFKKIVYVSCDPMSLREDSILLTKQYFLNSLQPVDMFPRTDHVETVAVFRNKNLI

Sequences:

>Translated_399_residues
MTTTKTGNSICTHFGTCGGCNYLDIDYTKELRKKEQNIKELFKAYRHVEIKTIVPSPSPEYYRHKIQLPFGRRIVGNKTL
LTLGLFNKEASFVLDQTECQIQDPGLTEVALAVKQWARREGLLPYNEKSKRGMMKYLVARKSITTGEIIVGIVTAKEDLP
HAKDASKRLHTAIQNRIGKTGKFGKLVGIIHNINTKHTTMALGREEHLLWGRPYIHEHFGKHKFRVGLSTFLQVNPIQTP
SLYNLVLDEIEKDSRVIDAYSGIGTISFWIAGQSKEVLGIEENPNSHRTALESLKYNKVHNVRFRKGRVAEVLPTLYGKN
YDTIVLDPPRTGLGAEVTETILAMGFKKIVYVSCDPMSLREDSILLTKQYFLNSLQPVDMFPRTDHVETVAVFRNKNLI
>Mature_398_residues
TTTKTGNSICTHFGTCGGCNYLDIDYTKELRKKEQNIKELFKAYRHVEIKTIVPSPSPEYYRHKIQLPFGRRIVGNKTLL
TLGLFNKEASFVLDQTECQIQDPGLTEVALAVKQWARREGLLPYNEKSKRGMMKYLVARKSITTGEIIVGIVTAKEDLPH
AKDASKRLHTAIQNRIGKTGKFGKLVGIIHNINTKHTTMALGREEHLLWGRPYIHEHFGKHKFRVGLSTFLQVNPIQTPS
LYNLVLDEIEKDSRVIDAYSGIGTISFWIAGQSKEVLGIEENPNSHRTALESLKYNKVHNVRFRKGRVAEVLPTLYGKNY
DTIVLDPPRTGLGAEVTETILAMGFKKIVYVSCDPMSLREDSILLTKQYFLNSLQPVDMFPRTDHVETVAVFRNKNLI

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RNA M5U methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=203, Percent_Identity=30.5418719211823, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI51173878, Length=203, Percent_Identity=30.5418719211823, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI269784680, Length=206, Percent_Identity=29.6116504854369, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI269784676, Length=206, Percent_Identity=29.6116504854369, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI20149688, Length=206, Percent_Identity=29.6116504854369, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI269784678, Length=206, Percent_Identity=29.6116504854369, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1789148, Length=390, Percent_Identity=24.8717948717949, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787083, Length=382, Percent_Identity=22.7748691099476, Blast_Score=99, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24666579, Length=396, Percent_Identity=26.2626262626263, Blast_Score=112, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010280 [H]

Pfam domain/function: PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 45285; Mature: 45154

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTKTGNSICTHFGTCGGCNYLDIDYTKELRKKEQNIKELFKAYRHVEIKTIVPSPSPE
CCCCCCCCHHHHHCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCHH
YYRHKIQLPFGRRIVGNKTLLTLGLFNKEASFVLDQTECQIQDPGLTEVALAVKQWARRE
HHHEEEECCCCCEEECCCEEEEEEECCCCCCEEEECCCCEECCCCHHHHHHHHHHHHHHC
GLLPYNEKSKRGMMKYLVARKSITTGEIIVGIVTAKEDLPHAKDASKRLHTAIQNRIGKT
CCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCC
GKFGKLVGIIHNINTKHTTMALGREEHLLWGRPYIHEHFGKHKFRVGLSTFLQVNPIQTP
CCCHHHHHHEECCCCCCEEEECCCCCCEEECCCHHHHHCCCCEEEEEEEHEEEECCCCCC
SLYNLVLDEIEKDSRVIDAYSGIGTISFWIAGQSKEVLGIEENPNSHRTALESLKYNKVH
HHHHHHHHHHCCCCCEEEHHCCCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHCCCCC
NVRFRKGRVAEVLPTLYGKNYDTIVLDPPRTGLGAEVTETILAMGFKKIVYVSCDPMSLR
CEEECCCCHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHCCEEEEEEECCCCCCC
EDSILLTKQYFLNSLQPVDMFPRTDHVETVAVFRNKNLI
CCCEEEEHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
TTTKTGNSICTHFGTCGGCNYLDIDYTKELRKKEQNIKELFKAYRHVEIKTIVPSPSPE
CCCCCCCHHHHHCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCHH
YYRHKIQLPFGRRIVGNKTLLTLGLFNKEASFVLDQTECQIQDPGLTEVALAVKQWARRE
HHHEEEECCCCCEEECCCEEEEEEECCCCCCEEEECCCCEECCCCHHHHHHHHHHHHHHC
GLLPYNEKSKRGMMKYLVARKSITTGEIIVGIVTAKEDLPHAKDASKRLHTAIQNRIGKT
CCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCC
GKFGKLVGIIHNINTKHTTMALGREEHLLWGRPYIHEHFGKHKFRVGLSTFLQVNPIQTP
CCCHHHHHHEECCCCCCEEEECCCCCCEEECCCHHHHHCCCCEEEEEEEHEEEECCCCCC
SLYNLVLDEIEKDSRVIDAYSGIGTISFWIAGQSKEVLGIEENPNSHRTALESLKYNKVH
HHHHHHHHHHCCCCCEEEHHCCCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHCCCCC
NVRFRKGRVAEVLPTLYGKNYDTIVLDPPRTGLGAEVTETILAMGFKKIVYVSCDPMSLR
CEEECCCCHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHCCEEEEEEECCCCCCC
EDSILLTKQYFLNSLQPVDMFPRTDHVETVAVFRNKNLI
CCCEEEEHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA