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The map label for this gene is pgi

Identifier: 183219501

GI number: 183219501

Start: 74208

End: 75560

Strand: Direct

Name: pgi

Synonym: LEPBI_I0074

Alternate gene names: 183219501

Gene position: 74208-75560 (Clockwise)

Preceding gene: 183219498

Following gene: 183219506

Centisome position: 2.06

GC content: 40.35

Gene sequence:

>1353_bases
ATGTCGAATCTAAAAATTTCAGATCGCTTTGTGAAACCCTTTCTTGACCAATCCAAATTGGAGAAAGAATTGGAAAGAGC
GGAAATGGCTCGGCAAACCGTACTCAATGGATCCGGATTAGGAAATGAATTTTTAGGATGGGTAAACCTTCCTAGCCAAA
CAAAAGCAGAAGATTTACAAAACATCCGAAAGGCGGCTGAGTTGATTCAGTCCCATTCTCAATACCTAGTGGTAGTTGGA
ATCGGTGGCAGTTACCTAGGTGCTCGCGCTGTCATCGAAGCTCTCACCCCTGAGTTTAGCACTCCTGAAACACAAAAGAA
AACGGTTAAAATTTTATACGCTGGGCATCATTTGGATGCGGATTATCATTTTCGACTGCTTGCTTTTTTAGAAAACAAAG
AGTTTTCTGTGAATGTCATTTCAAAGTCTGGTACCACGACGGAGCCGGCAATCGCCTTTCGGTTGTTACTTTCTTTGCTC
GAAAGAAAGTATGGAAAAGAAAATATCAAACATCGTGTGTTTGCCACTACCGATAGGTCCAAAGGGGCACTCAAACACCT
AGCAGATGAGTATAAATTTCCTACTTTTGTGATCCCTGATGATGTGGGGGGAAGGTACTCTGTCTTCACACCCGTTGGAC
TGCTTCCCATTGCTGCCGCAGGTTTTAGTATCAATAAATTGATGGATGGAGCCAAACAAATGGAATCCGAATTAAAATCC
ACTGCATCCAAAGATGGGAACTTAGCGTGTTTTTACGCTGCCATTCGGAATGGTTTGTATTCCTTGGGCAAAACAACTGA
AATTTTTGTGTCATATAACCCTTCGTTTGGTTATGTCTCTGAGTGGTGGAAACAATTGTTTGGAGAAAGTGAAGGTAAAA
ATGGAAAAGGTATTTTCCCTGCTTCTGTTCAATTCACGACGGACTTACACTCGATGGGCCAGTACATCCAGGATGGAGAA
AGGAAATTGATGGAGACAGTCATCAAAGTGGAAGCACCTAAACAAGATGTCTATCTTACCGAAAAAACAGATGATAATGA
TGGATTGAATTATTTAGCAGGGAAAAAACTTTCTGAAGTCAATCAAAGTGCAATGCTTGGAACGTTGATTGCACATAAAG
ATGGTGGAGTTCCCTGTTTGGAAATTACTTTACCATCGATCAATGAGGAAACATTGGGGGAATTGTTGTATTTTTATGAA
TTCTCCTGTGCTGTTTCAGGTTATATGTTAGGTGTTAATCCTTTTGACCAACCCGGTGTCGAAGATTATAAAAATAATAT
GTTTGCTCTGTTGGGTAAAAAAGGATATGAAAAACGAAAGGAAGAAATCCTAAGCCATCTTGGATTTAGCTAA

Upstream 100 bases:

>100_bases
TTTCCAAATATATGTTCAAATTGATTCAAATTTTCTTTACTTCTCAATGAATCCACTTCATCTTCCTTTCGATGCTATAC
TTTATTTTAGGACAGGTGCT

Downstream 100 bases:

>100_bases
AAAACTTTTTATCTGTTCGAGTGATTTTCCAAACACATCTTTTGTTTGGTAAGTTTCCCAAAGTTCTTTTGTTCCTAAAT
CTAACACTTCGCCGGGGAAA

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MSNLKISDRFVKPFLDQSKLEKELERAEMARQTVLNGSGLGNEFLGWVNLPSQTKAEDLQNIRKAAELIQSHSQYLVVVG
IGGSYLGARAVIEALTPEFSTPETQKKTVKILYAGHHLDADYHFRLLAFLENKEFSVNVISKSGTTTEPAIAFRLLLSLL
ERKYGKENIKHRVFATTDRSKGALKHLADEYKFPTFVIPDDVGGRYSVFTPVGLLPIAAAGFSINKLMDGAKQMESELKS
TASKDGNLACFYAAIRNGLYSLGKTTEIFVSYNPSFGYVSEWWKQLFGESEGKNGKGIFPASVQFTTDLHSMGQYIQDGE
RKLMETVIKVEAPKQDVYLTEKTDDNDGLNYLAGKKLSEVNQSAMLGTLIAHKDGGVPCLEITLPSINEETLGELLYFYE
FSCAVSGYMLGVNPFDQPGVEDYKNNMFALLGKKGYEKRKEEILSHLGFS

Sequences:

>Translated_450_residues
MSNLKISDRFVKPFLDQSKLEKELERAEMARQTVLNGSGLGNEFLGWVNLPSQTKAEDLQNIRKAAELIQSHSQYLVVVG
IGGSYLGARAVIEALTPEFSTPETQKKTVKILYAGHHLDADYHFRLLAFLENKEFSVNVISKSGTTTEPAIAFRLLLSLL
ERKYGKENIKHRVFATTDRSKGALKHLADEYKFPTFVIPDDVGGRYSVFTPVGLLPIAAAGFSINKLMDGAKQMESELKS
TASKDGNLACFYAAIRNGLYSLGKTTEIFVSYNPSFGYVSEWWKQLFGESEGKNGKGIFPASVQFTTDLHSMGQYIQDGE
RKLMETVIKVEAPKQDVYLTEKTDDNDGLNYLAGKKLSEVNQSAMLGTLIAHKDGGVPCLEITLPSINEETLGELLYFYE
FSCAVSGYMLGVNPFDQPGVEDYKNNMFALLGKKGYEKRKEEILSHLGFS
>Mature_449_residues
SNLKISDRFVKPFLDQSKLEKELERAEMARQTVLNGSGLGNEFLGWVNLPSQTKAEDLQNIRKAAELIQSHSQYLVVVGI
GGSYLGARAVIEALTPEFSTPETQKKTVKILYAGHHLDADYHFRLLAFLENKEFSVNVISKSGTTTEPAIAFRLLLSLLE
RKYGKENIKHRVFATTDRSKGALKHLADEYKFPTFVIPDDVGGRYSVFTPVGLLPIAAAGFSINKLMDGAKQMESELKST
ASKDGNLACFYAAIRNGLYSLGKTTEIFVSYNPSFGYVSEWWKQLFGESEGKNGKGIFPASVQFTTDLHSMGQYIQDGER
KLMETVIKVEAPKQDVYLTEKTDDNDGLNYLAGKKLSEVNQSAMLGTLIAHKDGGVPCLEITLPSINEETLGELLYFYEF
SCAVSGYMLGVNPFDQPGVEDYKNNMFALLGKKGYEKRKEEILSHLGFS

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): G6PI_LEPBA (B0S9I4)

Other databases:

- EMBL:   CP000777
- RefSeq:   YP_001961199.1
- ProteinModelPortal:   B0S9I4
- SMR:   B0S9I4
- GeneID:   6388906
- GenomeReviews:   CP000777_GR
- KEGG:   lbf:LBF_0074
- HOGENOM:   HBG615843
- OMA:   YVNDRAY
- ProtClustDB:   CLSK2336180
- BioCyc:   LBIF355278:LBF_0074-MONOMER
- GO:   GO:0005737
- GO:   GO:0006094
- GO:   GO:0006096
- HAMAP:   MF_00473
- InterPro:   IPR001672
- InterPro:   IPR018189
- PANTHER:   PTHR11469
- PRINTS:   PR00662

Pfam domain/function: PF00342 PGI

EC number: =5.3.1.9

Molecular weight: Translated: 50025; Mature: 49893

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1; PS00174 P_GLUCOSE_ISOMERASE_2; PS51463 P_GLUCOSE_ISOMERASE_3

Important sites: ACT_SITE 310-310 ACT_SITE 424-424

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLKISDRFVKPFLDQSKLEKELERAEMARQTVLNGSGLGNEFLGWVNLPSQTKAEDLQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHH
NIRKAAELIQSHSQYLVVVGIGGSYLGARAVIEALTPEFSTPETQKKTVKILYAGHHLDA
HHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCC
DYHFRLLAFLENKEFSVNVISKSGTTTEPAIAFRLLLSLLERKYGKENIKHRVFATTDRS
CHHEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCHHHHCEEEEEECCCC
KGALKHLADEYKFPTFVIPDDVGGRYSVFTPVGLLPIAAAGFSINKLMDGAKQMESELKS
HHHHHHHHHHHCCCEEEECCCCCCCEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TASKDGNLACFYAAIRNGLYSLGKTTEIFVSYNPSFGYVSEWWKQLFGESEGKNGKGIFP
HHCCCCCEEEEHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCC
ASVQFTTDLHSMGQYIQDGERKLMETVIKVEAPKQDVYLTEKTDDNDGLNYLAGKKLSEV
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHCCHHHHH
NQSAMLGTLIAHKDGGVPCLEITLPSINEETLGELLYFYEFSCAVSGYMLGVNPFDQPGV
HHHHHHHHHHEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCH
EDYKNNMFALLGKKGYEKRKEEILSHLGFS
HHHHCCEEEECCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SNLKISDRFVKPFLDQSKLEKELERAEMARQTVLNGSGLGNEFLGWVNLPSQTKAEDLQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHH
NIRKAAELIQSHSQYLVVVGIGGSYLGARAVIEALTPEFSTPETQKKTVKILYAGHHLDA
HHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCC
DYHFRLLAFLENKEFSVNVISKSGTTTEPAIAFRLLLSLLERKYGKENIKHRVFATTDRS
CHHEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCHHHHCEEEEEECCCC
KGALKHLADEYKFPTFVIPDDVGGRYSVFTPVGLLPIAAAGFSINKLMDGAKQMESELKS
HHHHHHHHHHHCCCEEEECCCCCCCEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TASKDGNLACFYAAIRNGLYSLGKTTEIFVSYNPSFGYVSEWWKQLFGESEGKNGKGIFP
HHCCCCCEEEEHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCC
ASVQFTTDLHSMGQYIQDGERKLMETVIKVEAPKQDVYLTEKTDDNDGLNYLAGKKLSEV
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHCCHHHHH
NQSAMLGTLIAHKDGGVPCLEITLPSINEETLGELLYFYEFSCAVSGYMLGVNPFDQPGV
HHHHHHHHHHEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCH
EDYKNNMFALLGKKGYEKRKEEILSHLGFS
HHHHCCEEEECCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA