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The map label for this gene is trpG1 [H]

Identifier: 183219456

GI number: 183219456

Start: 30085

End: 30690

Strand: Direct

Name: trpG1 [H]

Synonym: LEPBI_I0029

Alternate gene names: 183219456

Gene position: 30085-30690 (Clockwise)

Preceding gene: 183219455

Following gene: 183219459

Centisome position: 0.84

GC content: 40.59

Gene sequence:

>606_bases
ATGAAAGTTCTCATCTTAGATAATTACGATTCCTTCACTTATAATTTATACCAAATCGTGGGAGAAATTTTAGAAGAACA
GGAAAAACTTTTTGAATTGGATGTAATCCGAAATGATGAAAAATCGTTCTCTGAAATAAAAGCAGCTAACTACGATAAGG
TTATTATTTCTCCAGGTCCAGGCCACCCAGCAGATCCGACCTATTTTGGAGTGAGCGCTGATATCTTAAAAGGACTCGGA
ACTTTGACCCCAATCCTTGGAATTTGCTTAGGAATGCAAGGTATGGCGACTGTGTTTGGAGGAGAAGTGGTGCGTGCAAA
AGTAGCCATGCATGGAAAACTTTCCCCAATTTCCCATGATGGGAAAGGCGTATTCTCTGGATTGACTCAAAATATTGAAA
TCATGCGTTACCATTCCCTCGTGGCAAAAGAAGAATCCTTACCAGATGAATTGGAAGTGACAGCACGGGTTTCTTCGGGA
GAAGGAAAGGGAGAAATCATGGGACTACGCCACAAATCTTTGAAAATTGAAGGGGTGCAATTCCATCCTGAATCCTTTGG
CTCAGAAGAAGGGAAGGAATTACTACGTAATTTTATCTATCGGTAA

Upstream 100 bases:

>100_bases
AAGAAATCATCAATAAAATGGCTTCTGTGAGAAAGGCTTTGGACTTACACCAACTGCCTCAAGAAAAAAATACAAAGGCA
AAAGGGTAAGTGGGTCAATC

Downstream 100 bases:

>100_bases
ATAGATTACAAAATCAAATGATCGAAATTCTCGACTCAAACGCATCTATTTCAAGTCACCTAACATTGCTTCTTCCCAAG
CCGCAAAAAAATCAAAGTCA

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MKVLILDNYDSFTYNLYQIVGEILEEQEKLFELDVIRNDEKSFSEIKAANYDKVIISPGPGHPADPTYFGVSADILKGLG
TLTPILGICLGMQGMATVFGGEVVRAKVAMHGKLSPISHDGKGVFSGLTQNIEIMRYHSLVAKEESLPDELEVTARVSSG
EGKGEIMGLRHKSLKIEGVQFHPESFGSEEGKELLRNFIYR

Sequences:

>Translated_201_residues
MKVLILDNYDSFTYNLYQIVGEILEEQEKLFELDVIRNDEKSFSEIKAANYDKVIISPGPGHPADPTYFGVSADILKGLG
TLTPILGICLGMQGMATVFGGEVVRAKVAMHGKLSPISHDGKGVFSGLTQNIEIMRYHSLVAKEESLPDELEVTARVSSG
EGKGEIMGLRHKSLKIEGVQFHPESFGSEEGKELLRNFIYR
>Mature_201_residues
MKVLILDNYDSFTYNLYQIVGEILEEQEKLFELDVIRNDEKSFSEIKAANYDKVIISPGPGHPADPTYFGVSADILKGLG
TLTPILGICLGMQGMATVFGGEVVRAKVAMHGKLSPISHDGKGVFSGLTQNIEIMRYHSLVAKEESLPDELEVTARVSSG
EGKGEIMGLRHKSLKIEGVQFHPESFGSEEGKELLRNFIYR

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI4504035, Length=200, Percent_Identity=30.5, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1789760, Length=199, Percent_Identity=47.7386934673367, Blast_Score=189, Evalue=1e-49,
Organism=Escherichia coli, GI1787517, Length=196, Percent_Identity=36.734693877551, Blast_Score=115, Evalue=1e-27,
Organism=Escherichia coli, GI1786215, Length=161, Percent_Identity=31.6770186335404, Blast_Score=65, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322638, Length=197, Percent_Identity=47.7157360406091, Blast_Score=178, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6324361, Length=212, Percent_Identity=29.2452830188679, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 22177; Mature: 22177

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLILDNYDSFTYNLYQIVGEILEEQEKLFELDVIRNDEKSFSEIKAANYDKVIISPGP
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCCC
GHPADPTYFGVSADILKGLGTLTPILGICLGMQGMATVFGGEVVRAKVAMHGKLSPISHD
CCCCCCCEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHCCCCCCCCCC
GKGVFSGLTQNIEIMRYHSLVAKEESLPDELEVTARVSSGEGKGEIMGLRHKSLKIEGVQ
CCHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEEEEEECCEEEEEEE
FHPESFGSEEGKELLRNFIYR
ECCHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKVLILDNYDSFTYNLYQIVGEILEEQEKLFELDVIRNDEKSFSEIKAANYDKVIISPGP
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCCC
GHPADPTYFGVSADILKGLGTLTPILGICLGMQGMATVFGGEVVRAKVAMHGKLSPISHD
CCCCCCCEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHCCCCCCCCCC
GKGVFSGLTQNIEIMRYHSLVAKEESLPDELEVTARVSSGEGKGEIMGLRHKSLKIEGVQ
CCHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEEEEEECCEEEEEEE
FHPESFGSEEGKELLRNFIYR
ECCHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703466 [H]