Click here to switch to the map view.

The map label for this gene is sodB [H]

Identifier: 183219454

GI number: 183219454

Start: 27979

End: 28551

Strand: Direct

Name: sodB [H]

Synonym: LEPBI_I0027

Alternate gene names: 183219454

Gene position: 27979-28551 (Clockwise)

Preceding gene: 183219453

Following gene: 183219455

Centisome position: 0.78

GC content: 40.66

Gene sequence:

>573_bases
ATGGAACATAAACTCCCAGAACTTCCTTATGCAAAGGATGCACTCGCTCCCCATATATCTGCAGAAACATTAGAGTTTCA
CTATGGAAAACACCACCAAACTTACATTACTAACTTAAACAATCTCATCAAAGGGACTGAATTTGAAAGTGCATCTTTGG
AAGACATCGTGAAAAAATCTTCTGGAGGTATTTTTAATAATGCCGCACAGGTTTGGAACCATACATTTTACTGGCACTCC
CTTTCACCAAATGGCGGAGGAGCTCCAAAAGGTGCCGTTGCAGACCTCATCACAAAATCCTTCGGTTCTTTTGATGCATT
CAAAGAAAAATTCACACAATCCGCTGTGACGAACTTTGGATCAGGTTGGACATGGCTTGTGAAAAAAGGAGACGGTTTGG
AAATCGTCAATACCAGTAACGCGGGAAGCCCTCTAAAAGATGGAATGCAAGCGCTCCTTACGATTGATGTTTGGGAACAT
GCATACTACATTGATTTCCGAAATGCACGCCCTAAATATGTGGAAGCATTCTGGAATTTAGTGAATTGGGATTTCGCAAA
TAAAAATCTTTAA

Upstream 100 bases:

>100_bases
GAATGATTAGAATCATTCTACTTTTTTAGTTTACGATTTGCTTTTGTGAATGAGACTAGAGACAAAATACAAATACACTT
GAATCCATCAGGAGACCACC

Downstream 100 bases:

>100_bases
AATCGGATTCTAATCTGAAACCAGAAAAGGCAGGTTCCGGAATCCGGCGCCTGCCTTTTTTATTTCTAAAATAGATTCAA
AATGAATCTTGGTAACAAAC

Product: superoxide dismutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MEHKLPELPYAKDALAPHISAETLEFHYGKHHQTYITNLNNLIKGTEFESASLEDIVKKSSGGIFNNAAQVWNHTFYWHS
LSPNGGGAPKGAVADLITKSFGSFDAFKEKFTQSAVTNFGSGWTWLVKKGDGLEIVNTSNAGSPLKDGMQALLTIDVWEH
AYYIDFRNARPKYVEAFWNLVNWDFANKNL

Sequences:

>Translated_190_residues
MEHKLPELPYAKDALAPHISAETLEFHYGKHHQTYITNLNNLIKGTEFESASLEDIVKKSSGGIFNNAAQVWNHTFYWHS
LSPNGGGAPKGAVADLITKSFGSFDAFKEKFTQSAVTNFGSGWTWLVKKGDGLEIVNTSNAGSPLKDGMQALLTIDVWEH
AYYIDFRNARPKYVEAFWNLVNWDFANKNL
>Mature_190_residues
MEHKLPELPYAKDALAPHISAETLEFHYGKHHQTYITNLNNLIKGTEFESASLEDIVKKSSGGIFNNAAQVWNHTFYWHS
LSPNGGGAPKGAVADLITKSFGSFDAFKEKFTQSAVTNFGSGWTWLVKKGDGLEIVNTSNAGSPLKDGMQALLTIDVWEH
AYYIDFRNARPKYVEAFWNLVNWDFANKNL

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=195, Percent_Identity=43.5897435897436, Blast_Score=161, Evalue=3e-40,
Organism=Homo sapiens, GI67782305, Length=195, Percent_Identity=43.5897435897436, Blast_Score=161, Evalue=3e-40,
Organism=Homo sapiens, GI67782309, Length=187, Percent_Identity=36.3636363636364, Blast_Score=120, Evalue=5e-28,
Organism=Escherichia coli, GI1787946, Length=191, Percent_Identity=70.6806282722513, Blast_Score=289, Evalue=1e-79,
Organism=Escherichia coli, GI1790342, Length=200, Percent_Identity=42, Blast_Score=162, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17569479, Length=192, Percent_Identity=38.0208333333333, Blast_Score=132, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI17506561, Length=194, Percent_Identity=37.6288659793814, Blast_Score=130, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6321796, Length=211, Percent_Identity=34.1232227488152, Blast_Score=110, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17136812, Length=190, Percent_Identity=40.5263157894737, Blast_Score=133, Evalue=7e-32,

Paralogues:

None

Copy number: 2020 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 900 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 21285; Mature: 21285

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHKLPELPYAKDALAPHISAETLEFHYGKHHQTYITNLNNLIKGTEFESASLEDIVKKS
CCCCCCCCCCCHHHHCCCCCHHHHEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
SGGIFNNAAQVWNHTFYWHSLSPNGGGAPKGAVADLITKSFGSFDAFKEKFTQSAVTNFG
CCCCCHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
SGWTWLVKKGDGLEIVNTSNAGSPLKDGMQALLTIDVWEHAYYIDFRNARPKYVEAFWNL
CCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHEECCEEEEEEECCCCHHHHHHHHHH
VNWDFANKNL
HHCCCCCCCC
>Mature Secondary Structure
MEHKLPELPYAKDALAPHISAETLEFHYGKHHQTYITNLNNLIKGTEFESASLEDIVKKS
CCCCCCCCCCCHHHHCCCCCHHHHEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
SGGIFNNAAQVWNHTFYWHSLSPNGGGAPKGAVADLITKSFGSFDAFKEKFTQSAVTNFG
CCCCCHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
SGWTWLVKKGDGLEIVNTSNAGSPLKDGMQALLTIDVWEHAYYIDFRNARPKYVEAFWNL
CCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHEECCEEEEEEECCCCHHHHHHHHHH
VNWDFANKNL
HHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8181762; 12910271 [H]