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The map label for this gene is trxR [H]

Identifier: 18311336

GI number: 18311336

Start: 2713169

End: 2714029

Strand: Reverse

Name: trxR [H]

Synonym: CPE2354

Alternate gene names: 18311336

Gene position: 2714029-2713169 (Counterclockwise)

Preceding gene: 18311337

Following gene: 18311333

Centisome position: 89.53

GC content: 32.17

Gene sequence:

>861_bases
TTGAGCGAAAGATATGATATAGCTATAATAGGAAGCGGACCAGCTGGCCTTTCAGCTGCATTAAATGCAAAAATTAGAAA
TAAAAAATTTATTCTTTTTGGTAATAATGATTTAAGTACAAAGCTTGTTAAAGCTCCAAAGGTAAATAACTATCTTGGAT
TCGTTGGAAAAGATGGTATGGATCTTAAGAATCAATTTATGGGTCATCTAAAAGAGATGGATATAGAGATAACAGAGGAA
AGAATAAATAGTATTTATGCTATGGGAGAATATTTCGCTCTTATGGTAAATGAAAAGATGTATGAAGCCACTTCAATAAT
CATAGCAACAGGTATTGAATACACAAAACCTATGAAGGGTGAAGAAGAATTCTTAGGTAAAGGTGTAGGATACTGTGCTA
CTTGTGATGCCCCTTTATATAAAGAAAAAACTGTAACTATAATTGGCTATAATAAAGAAGCTGAAGAGGAAGCTAATTTT
GTAAGTGAATTAGCAGCTAAGGTTTACTATATTCCTAGATATAAGGGAGAATTTGATTTAAATTCAGAAATTGAAGTTAT
TAATGATATTCCTGTAGAAATACAAGGGGATAGTAAGGTTACTAAATTAGTAACTAAAAATGGTGAAATAGAGACTGATG
GTATATTTGTATTAAGAGATAGTATATCACCAGGACAATTAGTGCCAGGATTAAAAATAACTGATGATCACATAGAAGTT
GATAGATTAATGAAGACTAATATAGAAGGATGTTTTGCTGCGGGAGATTGTACTGGTAGACCATACCAATATATGAAGGC
TGCAGGTGAAGGAAATGTGGCTGCTTTAAGTGCAGTAGCATACTTAGACAGTAAGAAATAA

Upstream 100 bases:

>100_bases
GAAAAGTTGTTGATACTTTAGTTGGCTTTAGACCAAAGGCTGCATTAGTTGAAGCTATCAAAAAATACGTTTAATAAGCT
TCTTAAGGAGATGAATAATT

Downstream 100 bases:

>100_bases
AAAAAGCTAACACATTGTGTTAGCTTTTTCTTTAGGTAACATTAAAAAATACATGTTGACCTATACTTTTTTCTCCAGTC
TTTTCGACGCCTTTCATCCA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR; General stress protein 35; GSP35 [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MSERYDIAIIGSGPAGLSAALNAKIRNKKFILFGNNDLSTKLVKAPKVNNYLGFVGKDGMDLKNQFMGHLKEMDIEITEE
RINSIYAMGEYFALMVNEKMYEATSIIIATGIEYTKPMKGEEEFLGKGVGYCATCDAPLYKEKTVTIIGYNKEAEEEANF
VSELAAKVYYIPRYKGEFDLNSEIEVINDIPVEIQGDSKVTKLVTKNGEIETDGIFVLRDSISPGQLVPGLKITDDHIEV
DRLMKTNIEGCFAAGDCTGRPYQYMKAAGEGNVAALSAVAYLDSKK

Sequences:

>Translated_286_residues
MSERYDIAIIGSGPAGLSAALNAKIRNKKFILFGNNDLSTKLVKAPKVNNYLGFVGKDGMDLKNQFMGHLKEMDIEITEE
RINSIYAMGEYFALMVNEKMYEATSIIIATGIEYTKPMKGEEEFLGKGVGYCATCDAPLYKEKTVTIIGYNKEAEEEANF
VSELAAKVYYIPRYKGEFDLNSEIEVINDIPVEIQGDSKVTKLVTKNGEIETDGIFVLRDSISPGQLVPGLKITDDHIEV
DRLMKTNIEGCFAAGDCTGRPYQYMKAAGEGNVAALSAVAYLDSKK
>Mature_285_residues
SERYDIAIIGSGPAGLSAALNAKIRNKKFILFGNNDLSTKLVKAPKVNNYLGFVGKDGMDLKNQFMGHLKEMDIEITEER
INSIYAMGEYFALMVNEKMYEATSIIIATGIEYTKPMKGEEEFLGKGVGYCATCDAPLYKEKTVTIIGYNKEAEEEANFV
SELAAKVYYIPRYKGEFDLNSEIEVINDIPVEIQGDSKVTKLVTKNGEIETDGIFVLRDSISPGQLVPGLKITDDHIEVD
RLMKTNIEGCFAAGDCTGRPYQYMKAAGEGNVAALSAVAYLDSKK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=29.8412698412698, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87081763, Length=267, Percent_Identity=29.5880149812734, Blast_Score=93, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320560, Length=313, Percent_Identity=30.3514376996805, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6321898, Length=318, Percent_Identity=26.1006289308176, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 31529; Mature: 31398

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERYDIAIIGSGPAGLSAALNAKIRNKKFILFGNNDLSTKLVKAPKVNNYLGFVGKDGM
CCCCEEEEEEECCCCCCHHHEEEEECCCEEEEECCCCCCEEEEECCCCCCEEEEECCCCC
DLKNQFMGHLKEMDIEITEERINSIYAMGEYFALMVNEKMYEATSIIIATGIEYTKPMKG
CHHHHHHHHHHHCCEEEEHHHHHHHHHHHHEEEEEECCHHHHHEEEEEEECCCCCCCCCC
EEEFLGKGVGYCATCDAPLYKEKTVTIIGYNKEAEEEANFVSELAAKVYYIPRYKGEFDL
CHHHHCCCCCEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHEEEECCCCCCCCC
NSEIEVINDIPVEIQGDSKVTKLVTKNGEIETDGIFVLRDSISPGQLVPGLKITDDHIEV
CCCEEEEECCCEEEECCCCEEEEEECCCCEECCCEEEEECCCCCCCCCCCCEEECCHHHH
DRLMKTNIEGCFAAGDCTGRPYQYMKAAGEGNVAALSAVAYLDSKK
HHHHHCCCCEEEEECCCCCCCHHHHHHCCCCCHHHHEEEEECCCCC
>Mature Secondary Structure 
SERYDIAIIGSGPAGLSAALNAKIRNKKFILFGNNDLSTKLVKAPKVNNYLGFVGKDGM
CCCEEEEEEECCCCCCHHHEEEEECCCEEEEECCCCCCEEEEECCCCCCEEEEECCCCC
DLKNQFMGHLKEMDIEITEERINSIYAMGEYFALMVNEKMYEATSIIIATGIEYTKPMKG
CHHHHHHHHHHHCCEEEEHHHHHHHHHHHHEEEEEECCHHHHHEEEEEEECCCCCCCCCC
EEEFLGKGVGYCATCDAPLYKEKTVTIIGYNKEAEEEANFVSELAAKVYYIPRYKGEFDL
CHHHHCCCCCEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHEEEECCCCCCCCC
NSEIEVINDIPVEIQGDSKVTKLVTKNGEIETDGIFVLRDSISPGQLVPGLKITDDHIEV
CCCEEEEECCCEEEECCCCEEEEEECCCCEECCCEEEEECCCCCCCCCCCCEEECCHHHH
DRLMKTNIEGCFAAGDCTGRPYQYMKAAGEGNVAALSAVAYLDSKK
HHHHHCCCCEEEEECCCCCCCHHHHHHCCCCCHHHHEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]