Click here to switch to the map view.

The map label for this gene is pdxK [H]

Identifier: 18311300

GI number: 18311300

Start: 2665305

End: 2666147

Strand: Reverse

Name: pdxK [H]

Synonym: CPE2318

Alternate gene names: 18311300

Gene position: 2666147-2665305 (Counterclockwise)

Preceding gene: 18311301

Following gene: 18311299

Centisome position: 87.95

GC content: 28.94

Gene sequence:

>843_bases
ATGAAACCTATGAATAAGATTGCTGCTATTCATGATATTTCATGCTATGGGAGGGCAGCATTAGCAACAATAATACCTAT
ATTATCTTCAATGGGAAATCAAGTATGTCCACTTCCAACAGCAGTATTGTCAACACATACAGATGGATTTGGAAAACCAG
CAATTAGAGATTTAAGTGATTTTATATATGAAACCAAAGATCATTGGAAAAGACTTAACTTAAATTTTCAATGCATATAT
AGTGGATATTTAGCTGATCCTAATCAAGTTAAATTTGTTGAAAGATTTATAGAAGATTTTAAGGAAGAGAATACTTTAGT
AGTTATAGATCCTGTTATGGCTGATAATGGTAAGCTTTATGATGGCATGAGTAAAAAAATGATTGAAGAAATGAGAACTT
TAATAAAAAGTGCAGATATAATCACTCCAAATATTACAGAAGCTTCTTTTCTTTTAGGAAAAGAATATAAAGAATCTCTA
AATGAAGATGAGATAAAAGAGTATTTAGTAGGTCTAGGAGATTTAGGACCTAAAATAAGTATAATAACAAGTGTAACAAG
TTCAAGAGGAAATGAATATATTGATACTGTACTCTATGATAGAGAAGAAAAAATGTTTTATACCTATTCTCATAAAAGAA
TAAATGCTTTTTATTGTGGAACAGGTGATGCTTTTGCCTCATTGCTAATAGGATGGATATTAAGAGGGGAAAGTATTGAA
AAAGCATTGGAGAAGTCATGTAATTTTATTGCAGAAGCTATAGAATATAGCGAAAAGTTTGATTATCCTCCAAATGAAGG
AATATTACTTGAAAGTTTGTTATATAAATTAATAAGTAAATAA

Upstream 100 bases:

>100_bases
ACATAAAAGTATGGGTACATTTGATATAAAAAAATTAAATTAATATAATACTAGGTAATAAGAATTTTATTTAAAAGCAG
ATTTTTAAGGGGAGATAGAA

Downstream 100 bases:

>100_bases
ATTATTAAAGTCAAAAAAATAAATTGACAAAGTAATTTTAGAATGATACTATTAAAAAAACAAAATTTAATAAATCTTAT
CAAGAGAGGTGGAGGGACTG

Product: pyridoxamine kinase

Products: NA

Alternate protein names: PN/PL/PM kinase; Pyridoxal kinase; Pyridoxamine kinase; Vitamin B6 kinase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MKPMNKIAAIHDISCYGRAALATIIPILSSMGNQVCPLPTAVLSTHTDGFGKPAIRDLSDFIYETKDHWKRLNLNFQCIY
SGYLADPNQVKFVERFIEDFKEENTLVVIDPVMADNGKLYDGMSKKMIEEMRTLIKSADIITPNITEASFLLGKEYKESL
NEDEIKEYLVGLGDLGPKISIITSVTSSRGNEYIDTVLYDREEKMFYTYSHKRINAFYCGTGDAFASLLIGWILRGESIE
KALEKSCNFIAEAIEYSEKFDYPPNEGILLESLLYKLISK

Sequences:

>Translated_280_residues
MKPMNKIAAIHDISCYGRAALATIIPILSSMGNQVCPLPTAVLSTHTDGFGKPAIRDLSDFIYETKDHWKRLNLNFQCIY
SGYLADPNQVKFVERFIEDFKEENTLVVIDPVMADNGKLYDGMSKKMIEEMRTLIKSADIITPNITEASFLLGKEYKESL
NEDEIKEYLVGLGDLGPKISIITSVTSSRGNEYIDTVLYDREEKMFYTYSHKRINAFYCGTGDAFASLLIGWILRGESIE
KALEKSCNFIAEAIEYSEKFDYPPNEGILLESLLYKLISK
>Mature_280_residues
MKPMNKIAAIHDISCYGRAALATIIPILSSMGNQVCPLPTAVLSTHTDGFGKPAIRDLSDFIYETKDHWKRLNLNFQCIY
SGYLADPNQVKFVERFIEDFKEENTLVVIDPVMADNGKLYDGMSKKMIEEMRTLIKSADIITPNITEASFLLGKEYKESL
NEDEIKEYLVGLGDLGPKISIITSVTSSRGNEYIDTVLYDREEKMFYTYSHKRINAFYCGTGDAFASLLIGWILRGESIE
KALEKSCNFIAEAIEYSEKFDYPPNEGILLESLLYKLISK

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxal, pyridoxine, and pyridoxamine as substrates [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=258, Percent_Identity=23.2558139534884, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1788758, Length=265, Percent_Identity=24.9056603773585, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17507759, Length=193, Percent_Identity=28.4974093264249, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17507757, Length=193, Percent_Identity=28.4974093264249, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320806, Length=221, Percent_Identity=28.0542986425339, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 31686; Mature: 31686

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPMNKIAAIHDISCYGRAALATIIPILSSMGNQVCPLPTAVLSTHTDGFGKPAIRDLSD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCHHHHHHHH
FIYETKDHWKRLNLNFQCIYSGYLADPNQVKFVERFIEDFKEENTLVVIDPVMADNGKLY
HHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECEECCCCCCC
DGMSKKMIEEMRTLIKSADIITPNITEASFLLGKEYKESLNEDEIKEYLVGLGDLGPKIS
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEE
IITSVTSSRGNEYIDTVLYDREEKMFYTYSHKRINAFYCGTGDAFASLLIGWILRGESIE
EEEHHHHHCCCHHHHHHHHCCCCCEEEEEECCEEEEEECCCHHHHHHHHHHHHHCCHHHH
KALEKSCNFIAEAIEYSEKFDYPPNEGILLESLLYKLISK
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKPMNKIAAIHDISCYGRAALATIIPILSSMGNQVCPLPTAVLSTHTDGFGKPAIRDLSD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCHHHHHHHH
FIYETKDHWKRLNLNFQCIYSGYLADPNQVKFVERFIEDFKEENTLVVIDPVMADNGKLY
HHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECEECCCCCCC
DGMSKKMIEEMRTLIKSADIITPNITEASFLLGKEYKESLNEDEIKEYLVGLGDLGPKIS
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEE
IITSVTSSRGNEYIDTVLYDREEKMFYTYSHKRINAFYCGTGDAFASLLIGWILRGESIE
EEEHHHHHCCCHHHHHHHHCCCCCEEEEEECCEEEEEECCCHHHHHHHHHHHHHCCHHHH
KALEKSCNFIAEAIEYSEKFDYPPNEGILLESLLYKLISK
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA