Click here to switch to the map view.

The map label for this gene is gcp

Identifier: 18311214

GI number: 18311214

Start: 2553958

End: 2554977

Strand: Reverse

Name: gcp

Synonym: CPE2232

Alternate gene names: 18311214

Gene position: 2554977-2553958 (Counterclockwise)

Preceding gene: 18311217

Following gene: 18311213

Centisome position: 84.28

GC content: 34.12

Gene sequence:

>1020_bases
ATGGATAAAAAAATTATATTAGCAATAGAAAGTAGTTGTGACGAAACAGCGGCAGCTGTAGTAGTCAATGGTAGAGAAGT
TTTATCAAATATAATATCTTCTCAGATAGATATACATACAAAATTTGGGGGAGTAGTCCCAGAGGTTGCATCAAGAAAAC
ACATAGAAGCTATAAATGCAGTGGTAGAGGAAGCCTTAGAAGTTGCAGGAGTAACATTTGATGACATAGATGCAATAGCA
GTTACATATGGTCCAGGGTTAGTTGGAGCACTTTTAGTGGGACTTCAATATGCTAAAGGATTAGCATACTCTTTAGATAA
ACCATTAATAGGAGTTAACCATATAGAAGGGCATATAAGTGCTAACTTTATAGATCATAAAGACTTAGAACCACCTTTTG
TTTGTTTAGTTGTTTCAGGAGGACACACTTTTGTAGTACATGTTGAAGACTATGGAAAGTTTGAAATAATAGGTGAAACA
AGAGATGATGCAGCAGGAGAAGCTTTTGACAAGGTGGCAAGAGCCGTAGGATTAGGATATCCAGGAGGACCTAAAATAGA
TAAATTAGCTAAGGAAGGAAATAGTGATGCTATAAAATTCCCAAAAGCTAATTTCCATGATGATACCTTAGATTTTTCAT
TTAGTGGAGTTAAATCAGCTGTCTTAAATTATTTAAATAAGATGGAAATGAAAAATGAAGAAATAAATAAAGCTGATGTT
GTAGCTAGTTTCCAAAAGGCCGTAGTTGAAGTATTAACTGATAATGCAATAAAAACTTGTAAGATGAGAAAGGCAGATAA
AATAGCCATTGCAGGTGGAGTTGCTTCTAATAGTGCTTTAAGAGAAAATCTTCTTAGAGAAGGAGAAAAGAGAGGAATAA
AGGTTTTATTCCCATCACCAATACTTTGTACAGATAATGCTGCCATGATAGGAAGTGCTGCATATTTTGAATTATTAAAG
GGAAATGTATCTGAAATGAGTCTTAACGCAAAACCTAATTTAAGATTAGGAGAAAGATAG

Upstream 100 bases:

>100_bases
CATAATGTAACATTATGTATTTACATTTCTTGAAAGTATTTAACAGATAAAGTATAATACTCTATGTTTACATGAAAAAT
TAAAATTAAGAGGGATAAAA

Downstream 100 bases:

>100_bases
GGGCTGAATTATCAATGAGGTTTATTCCGTACTCAAATGGATTTCATAAAATGAACAAAAATATAAAAATAAAGCCTATA
AACGTAATTAGGAATATTTT

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MDKKIILAIESSCDETAAAVVVNGREVLSNIISSQIDIHTKFGGVVPEVASRKHIEAINAVVEEALEVAGVTFDDIDAIA
VTYGPGLVGALLVGLQYAKGLAYSLDKPLIGVNHIEGHISANFIDHKDLEPPFVCLVVSGGHTFVVHVEDYGKFEIIGET
RDDAAGEAFDKVARAVGLGYPGGPKIDKLAKEGNSDAIKFPKANFHDDTLDFSFSGVKSAVLNYLNKMEMKNEEINKADV
VASFQKAVVEVLTDNAIKTCKMRKADKIAIAGGVASNSALRENLLREGEKRGIKVLFPSPILCTDNAAMIGSAAYFELLK
GNVSEMSLNAKPNLRLGER

Sequences:

>Translated_339_residues
MDKKIILAIESSCDETAAAVVVNGREVLSNIISSQIDIHTKFGGVVPEVASRKHIEAINAVVEEALEVAGVTFDDIDAIA
VTYGPGLVGALLVGLQYAKGLAYSLDKPLIGVNHIEGHISANFIDHKDLEPPFVCLVVSGGHTFVVHVEDYGKFEIIGET
RDDAAGEAFDKVARAVGLGYPGGPKIDKLAKEGNSDAIKFPKANFHDDTLDFSFSGVKSAVLNYLNKMEMKNEEINKADV
VASFQKAVVEVLTDNAIKTCKMRKADKIAIAGGVASNSALRENLLREGEKRGIKVLFPSPILCTDNAAMIGSAAYFELLK
GNVSEMSLNAKPNLRLGER
>Mature_339_residues
MDKKIILAIESSCDETAAAVVVNGREVLSNIISSQIDIHTKFGGVVPEVASRKHIEAINAVVEEALEVAGVTFDDIDAIA
VTYGPGLVGALLVGLQYAKGLAYSLDKPLIGVNHIEGHISANFIDHKDLEPPFVCLVVSGGHTFVVHVEDYGKFEIIGET
RDDAAGEAFDKVARAVGLGYPGGPKIDKLAKEGNSDAIKFPKANFHDDTLDFSFSGVKSAVLNYLNKMEMKNEEINKADV
VASFQKAVVEVLTDNAIKTCKMRKADKIAIAGGVASNSALRENLLREGEKRGIKVLFPSPILCTDNAAMIGSAAYFELLK
GNVSEMSLNAKPNLRLGER

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=329, Percent_Identity=37.0820668693009, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI8923380, Length=327, Percent_Identity=30.5810397553517, Blast_Score=130, Evalue=1e-30,
Organism=Escherichia coli, GI1789445, Length=333, Percent_Identity=40.5405405405405, Blast_Score=268, Evalue=5e-73,
Organism=Caenorhabditis elegans, GI17557464, Length=346, Percent_Identity=32.6589595375723, Blast_Score=146, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71995670, Length=323, Percent_Identity=30.030959752322, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320099, Length=342, Percent_Identity=32.4561403508772, Blast_Score=129, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6322891, Length=320, Percent_Identity=28.125, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI20129063, Length=340, Percent_Identity=32.3529411764706, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI21357207, Length=324, Percent_Identity=32.7160493827161, Blast_Score=130, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_CLOP1 (Q0TN80)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_696910.1
- ProteinModelPortal:   Q0TN80
- SMR:   Q0TN80
- STRING:   Q0TN80
- MEROPS:   M22.001
- GeneID:   4201125
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_2496
- TIGR:   CPF_2496
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- ProtClustDB:   PRK09604
- BioCyc:   CPER195103:CPF_2496-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36297; Mature: 36297

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKIILAIESSCDETAAAVVVNGREVLSNIISSQIDIHTKFGGVVPEVASRKHIEAINA
CCCEEEEEEECCCCCCEEEEEECCHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHH
VVEEALEVAGVTFDDIDAIAVTYGPGLVGALLVGLQYAKGLAYSLDKPLIGVNHIEGHIS
HHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCHHHHCCCCCEECCCCCCEEE
ANFIDHKDLEPPFVCLVVSGGHTFVVHVEDYGKFEIIGETRDDAAGEAFDKVARAVGLGY
EEECCCCCCCCCEEEEEEECCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHCCCC
PGGPKIDKLAKEGNSDAIKFPKANFHDDTLDFSFSGVKSAVLNYLNKMEMKNEEINKADV
CCCCCHHHHHHCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHH
VASFQKAVVEVLTDNAIKTCKMRKADKIAIAGGVASNSALRENLLREGEKRGIKVLFPSP
HHHHHHHHHHHHHCCHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEECCCC
ILCTDNAAMIGSAAYFELLKGNVSEMSLNAKPNLRLGER
EEECCCHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCCC
>Mature Secondary Structure
MDKKIILAIESSCDETAAAVVVNGREVLSNIISSQIDIHTKFGGVVPEVASRKHIEAINA
CCCEEEEEEECCCCCCEEEEEECCHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHH
VVEEALEVAGVTFDDIDAIAVTYGPGLVGALLVGLQYAKGLAYSLDKPLIGVNHIEGHIS
HHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCHHHHCCCCCEECCCCCCEEE
ANFIDHKDLEPPFVCLVVSGGHTFVVHVEDYGKFEIIGETRDDAAGEAFDKVARAVGLGY
EEECCCCCCCCCEEEEEEECCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHCCCC
PGGPKIDKLAKEGNSDAIKFPKANFHDDTLDFSFSGVKSAVLNYLNKMEMKNEEINKADV
CCCCCHHHHHHCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHH
VASFQKAVVEVLTDNAIKTCKMRKADKIAIAGGVASNSALRENLLREGEKRGIKVLFPSP
HHHHHHHHHHHHHCCHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEECCCC
ILCTDNAAMIGSAAYFELLKGNVSEMSLNAKPNLRLGER
EEECCCHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA