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The map label for this gene is lpxH

Identifier: 182682582

GI number: 182682582

Start: 2326190

End: 2326942

Strand: Reverse

Name: lpxH

Synonym: XfasM23_2070

Alternate gene names: 182682582

Gene position: 2326942-2326190 (Counterclockwise)

Preceding gene: 182682583

Following gene: 182682578

Centisome position: 91.77

GC content: 51.79

Gene sequence:

>753_bases
ATGACGACTTTGATTATTTCAGATCTGCATTTGGATCCGTTGCGTCCCGTGGTGACTGAATTATTTCTGCGATTCTTGCG
GGAACAGGTGTCTGGTGCCGATGCGCTTTATATTCTTGGCGACCTGTTTGAAATATGGATTGGTGACGATATGCCTTCAG
AAGTCGCCGACATGGTGGTGGCTGCGTTGCGTACCCACGCCGATGCGGGTACGCCGCTGTACTTCATGCCAGGTAACCGT
GATTTTCTGGTGGGTGCCGATTATGCAGCGCGTGCTGGTTTCCGGATTCTTCCGGATCCATGTGTCGTTGATCTCTATGG
GGAACCCACGCTCCTGTTACACGGTGACCTGTTATGTACAGACGATATCGCGTATCAAGCGTTCCGTGCGCAGACGCGTG
ACCCGGAATTCATTGCGCAGTTTTTGACGCAGACGCTTTCCGCGCGTCTTGCTTTTGCACAGCAGGCCCGTCTGGCCAGT
CACGCGCACCAGTCTGGATTGAAACAAGAAAATGATTCCACGCAGTTTGAAAAAATTACTGACGTAGTACCTGCTGATGT
TGCAGCGATGTTTGCTTGCTATGGGGTCAATCGAATGATTCATGGCCATACGCATCGCCCAGCGTTGCACATGTTGCAGG
TGGCTGAGTGTGCGTGCACGCGTGTAGTGCTTGGTGATTGGTATCAGCAAGGGTCAGTGTTGTGTGTGGATGCTGATGGT
CTTGTGTTGGAGCAGTTGTTATTGCCAGGTTGA

Upstream 100 bases:

>100_bases
TTTGGTTGCGATACGGTATTTTAAATTTTCTTTCAATATTTCAGTGATTGCGTCAGGTTTTACATGTAATCCTGCTCTCT
GGGTCTACTACAATGATTGA

Downstream 100 bases:

>100_bases
ATATGCGTTTGTGTTGCATTTCTTGGGACAAGAGTCGAGAAACAATTGCTTAGCTGGTATTGGCCTCAGCGATTTTTTCA
AAAATCTTTGTTTGATTCCT

Product: UDP-2,3-diacylglucosamine hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MTTLIISDLHLDPLRPVVTELFLRFLREQVSGADALYILGDLFEIWIGDDMPSEVADMVVAALRTHADAGTPLYFMPGNR
DFLVGADYAARAGFRILPDPCVVDLYGEPTLLLHGDLLCTDDIAYQAFRAQTRDPEFIAQFLTQTLSARLAFAQQARLAS
HAHQSGLKQENDSTQFEKITDVVPADVAAMFACYGVNRMIHGHTHRPALHMLQVAECACTRVVLGDWYQQGSVLCVDADG
LVLEQLLLPG

Sequences:

>Translated_250_residues
MTTLIISDLHLDPLRPVVTELFLRFLREQVSGADALYILGDLFEIWIGDDMPSEVADMVVAALRTHADAGTPLYFMPGNR
DFLVGADYAARAGFRILPDPCVVDLYGEPTLLLHGDLLCTDDIAYQAFRAQTRDPEFIAQFLTQTLSARLAFAQQARLAS
HAHQSGLKQENDSTQFEKITDVVPADVAAMFACYGVNRMIHGHTHRPALHMLQVAECACTRVVLGDWYQQGSVLCVDADG
LVLEQLLLPG
>Mature_249_residues
TTLIISDLHLDPLRPVVTELFLRFLREQVSGADALYILGDLFEIWIGDDMPSEVADMVVAALRTHADAGTPLYFMPGNRD
FLVGADYAARAGFRILPDPCVVDLYGEPTLLLHGDLLCTDDIAYQAFRAQTRDPEFIAQFLTQTLSARLAFAQQARLASH
AHQSGLKQENDSTQFEKITDVVPADVAAMFACYGVNRMIHGHTHRPALHMLQVAECACTRVVLGDWYQQGSVLCVDADGL
VLEQLLLPG

Specific function: Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP

COG id: COG2908

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxH family

Homologues:

Organism=Escherichia coli, GI1786735, Length=243, Percent_Identity=44.4444444444444, Blast_Score=200, Evalue=6e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LPXH_XYLF2 (B2I9U7)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001830742.1
- ProteinModelPortal:   B2I9U7
- GeneID:   6203529
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_2070
- HOGENOM:   HBG288883
- OMA:   CHGDTLC
- ProtClustDB:   PRK05340
- GO:   GO:0005737
- HAMAP:   MF_00575
- InterPro:   IPR004843
- InterPro:   IPR010138
- TIGRFAMs:   TIGR01854

Pfam domain/function: PF00149 Metallophos

EC number: 3.6.1.-

Molecular weight: Translated: 27587; Mature: 27456

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLIISDLHLDPLRPVVTELFLRFLREQVSGADALYILGDLFEIWIGDDMPSEVADMVV
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
AALRTHADAGTPLYFMPGNRDFLVGADYAARAGFRILPDPCVVDLYGEPTLLLHGDLLCT
HHHHHCCCCCCEEEEECCCCEEEEECCHHHHCCCEECCCCEEEEECCCCEEEEECCEEEC
DDIAYQAFRAQTRDPEFIAQFLTQTLSARLAFAQQARLASHAHQSGLKQENDSTQFEKIT
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
DVVPADVAAMFACYGVNRMIHGHTHRPALHMLQVAECACTRVVLGDWYQQGSVLCVDADG
HHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
LVLEQLLLPG
HHHHHHHCCC
>Mature Secondary Structure 
TTLIISDLHLDPLRPVVTELFLRFLREQVSGADALYILGDLFEIWIGDDMPSEVADMVV
CEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
AALRTHADAGTPLYFMPGNRDFLVGADYAARAGFRILPDPCVVDLYGEPTLLLHGDLLCT
HHHHHCCCCCCEEEEECCCCEEEEECCHHHHCCCEECCCCEEEEECCCCEEEEECCEEEC
DDIAYQAFRAQTRDPEFIAQFLTQTLSARLAFAQQARLASHAHQSGLKQENDSTQFEKIT
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
DVVPADVAAMFACYGVNRMIHGHTHRPALHMLQVAECACTRVVLGDWYQQGSVLCVDADG
HHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
LVLEQLLLPG
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA