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The map label for this gene is asnC

Identifier: 182682566

GI number: 182682566

Start: 2305321

End: 2306721

Strand: Direct

Name: asnC

Synonym: XfasM23_2054

Alternate gene names: 182682566

Gene position: 2305321-2306721 (Clockwise)

Preceding gene: 182682551

Following gene: 182682567

Centisome position: 90.91

GC content: 54.1

Gene sequence:

>1401_bases
ATGACGGTGGCTAGTGTTGAGCAAATGTTCTCCGGGAAAATTCAGGTGGGCAGTGAAGTGACAGTCCGTGGCTGGGTACG
AACCCGGCGCGATTCTAAAGCGGGTCTCAGTTTTGTCAGTGTCAGTGATGGTTCCTGCTTCGCCGCAATTCAGGTCGTCA
CTCCAGCGCATCTTCCAAATTACGAAACAGAAGTACGCAAACTCACTACAGGTTGCGCAGTCATCGTGATCGGCACCCTG
GCACCCTCTCTGGGCCAAGGTCAACAGTTCGAAATCCAGGCCCAGAGCATTGAGGTCGTCGGTTGGGTCGAGGATCCGGA
AACATATCCGATCCAACCCAAACAACATTCATTGGAATTCCTGCGGGAGGTGGCGCACCTGCGTCCACGCACCAATCTGT
TTGGTGCAGTCGCTCGTATCCGCCACTGTCTATCGCAGGCGGTACACCGTTTTTTTCACGAGAATGGTTATTACTGGATC
ACCACACCGATCATCACCACTTCCGACGCCGAAGGTGCCGGACAAATGTTCCGCGTCTCTACGCTGGATTTAGTCAATCT
ACCGCGCACGGAGACCGGCGGAATTGACTTTTCGCATGATTTCTTTGGAAAAGAAACGTTCTTGACCGTCTCCGGGCAAC
TCAACGTAGAAGCCTATGCACTGGCACTGAGCAAGGTGTATACCTTCGGCCCGACGTTCCGAGCTGAGAATAGTCACACG
CCGCGTCACCTTGCGGAATTTTGGATGATTGAGCCAGAAATCGCCTTCGCGGATCTGGCTGAGGATGCACGTGTGGCCGA
ACAGTTCCTCAAATTTCTTTTCAAAACGGTACTGGAGGAACGTGACGACGACTTGGCATTCATTACCGAACGGGTAGAGA
AAACCACGATCAGCAAGCTGGAAGGGTTTATCAATTCACCATTCGAACGGATCGAGTACACAGATGCCATCAAGCTGTTG
GAAAGGTCGGGGAAAAAGTTTGATTTTCCGGTTGAATGGGGACTGGATCTACAAACCGAGCACGAGCGCTGGTTGACCGA
GAAGCACATCGGCCGTCCGGTGGTGGTGACGAACTATCCCGAACACATCAAAGCTTTTTACATGCGGCTGAACGACGATG
GGAAAACGGTCGCGGCGATGGATGTGTTAGCCCCGGGCATCGGCGAAATTATTGGCGGCAGCCAACGTGAGGAGCGTTTG
GAAATGCTTGATATACGGATGGCGCAATTCGGTCTGGACCCGGCACATTACCAGTGGTATCGGGATTTTCGCCGCTACGG
CTCGGTGCCGCACGCGGGGTTCGGCCTGGGGTTTGAACGTCTCGTGGTCTACGTCTGCGGGCTGAGCAATATCCGCGATG
CAATCCCCTACCCGCGTGCGCCAGGCAGTGCCGAGTTCTGA

Upstream 100 bases:

>100_bases
TCTTCGAAGGAATCGCCACAATCGCCGCGCCAAGGCCATCAAGATACACTCGCGCGTTCAAGAAGAAAGATTCACTACGA
ATTAATTAAGGTGGAGCGTC

Downstream 100 bases:

>100_bases
AACAGGTCCGGCGACTGTCTGCGGCATGCCAATGGCGAGTGCGAACGTCATCGTCGTTCGCCACAGTGTACTGAACCATC
TCTGTCACATCATTTTAATC

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MTVASVEQMFSGKIQVGSEVTVRGWVRTRRDSKAGLSFVSVSDGSCFAAIQVVTPAHLPNYETEVRKLTTGCAVIVIGTL
APSLGQGQQFEIQAQSIEVVGWVEDPETYPIQPKQHSLEFLREVAHLRPRTNLFGAVARIRHCLSQAVHRFFHENGYYWI
TTPIITTSDAEGAGQMFRVSTLDLVNLPRTETGGIDFSHDFFGKETFLTVSGQLNVEAYALALSKVYTFGPTFRAENSHT
PRHLAEFWMIEPEIAFADLAEDARVAEQFLKFLFKTVLEERDDDLAFITERVEKTTISKLEGFINSPFERIEYTDAIKLL
ERSGKKFDFPVEWGLDLQTEHERWLTEKHIGRPVVVTNYPEHIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERL
EMLDIRMAQFGLDPAHYQWYRDFRRYGSVPHAGFGLGFERLVVYVCGLSNIRDAIPYPRAPGSAEF

Sequences:

>Translated_466_residues
MTVASVEQMFSGKIQVGSEVTVRGWVRTRRDSKAGLSFVSVSDGSCFAAIQVVTPAHLPNYETEVRKLTTGCAVIVIGTL
APSLGQGQQFEIQAQSIEVVGWVEDPETYPIQPKQHSLEFLREVAHLRPRTNLFGAVARIRHCLSQAVHRFFHENGYYWI
TTPIITTSDAEGAGQMFRVSTLDLVNLPRTETGGIDFSHDFFGKETFLTVSGQLNVEAYALALSKVYTFGPTFRAENSHT
PRHLAEFWMIEPEIAFADLAEDARVAEQFLKFLFKTVLEERDDDLAFITERVEKTTISKLEGFINSPFERIEYTDAIKLL
ERSGKKFDFPVEWGLDLQTEHERWLTEKHIGRPVVVTNYPEHIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERL
EMLDIRMAQFGLDPAHYQWYRDFRRYGSVPHAGFGLGFERLVVYVCGLSNIRDAIPYPRAPGSAEF
>Mature_465_residues
TVASVEQMFSGKIQVGSEVTVRGWVRTRRDSKAGLSFVSVSDGSCFAAIQVVTPAHLPNYETEVRKLTTGCAVIVIGTLA
PSLGQGQQFEIQAQSIEVVGWVEDPETYPIQPKQHSLEFLREVAHLRPRTNLFGAVARIRHCLSQAVHRFFHENGYYWIT
TPIITTSDAEGAGQMFRVSTLDLVNLPRTETGGIDFSHDFFGKETFLTVSGQLNVEAYALALSKVYTFGPTFRAENSHTP
RHLAEFWMIEPEIAFADLAEDARVAEQFLKFLFKTVLEERDDDLAFITERVEKTTISKLEGFINSPFERIEYTDAIKLLE
RSGKKFDFPVEWGLDLQTEHERWLTEKHIGRPVVVTNYPEHIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLE
MLDIRMAQFGLDPAHYQWYRDFRRYGSVPHAGFGLGFERLVVYVCGLSNIRDAIPYPRAPGSAEF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=465, Percent_Identity=42.7956989247312, Blast_Score=365, Evalue=1e-101,
Organism=Homo sapiens, GI4758762, Length=457, Percent_Identity=29.5404814004376, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI45439306, Length=350, Percent_Identity=28.8571428571429, Blast_Score=118, Evalue=1e-26,
Organism=Escherichia coli, GI1787161, Length=466, Percent_Identity=66.5236051502146, Blast_Score=678, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17556372, Length=430, Percent_Identity=32.7906976744186, Blast_Score=201, Evalue=7e-52,
Organism=Caenorhabditis elegans, GI71984122, Length=462, Percent_Identity=30.952380952381, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17551876, Length=341, Percent_Identity=30.4985337243402, Blast_Score=117, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6319872, Length=473, Percent_Identity=36.1522198731501, Blast_Score=278, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6321807, Length=472, Percent_Identity=31.1440677966102, Blast_Score=197, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6323011, Length=351, Percent_Identity=28.4900284900285, Blast_Score=110, Evalue=6e-25,
Organism=Drosophila melanogaster, GI19922416, Length=453, Percent_Identity=34.6578366445916, Blast_Score=277, Evalue=1e-74,
Organism=Drosophila melanogaster, GI19921528, Length=473, Percent_Identity=29.1754756871036, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI17136276, Length=340, Percent_Identity=28.5294117647059, Blast_Score=105, Evalue=5e-23,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 52657; Mature: 52526

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVASVEQMFSGKIQVGSEVTVRGWVRTRRDSKAGLSFVSVSDGSCFAAIQVVTPAHLPN
CCHHHHHHHHCCCEEECCEEEEEHHHHHCCCCCCCEEEEEECCCCEEEEEEEECCCCCCC
YETEVRKLTTGCAVIVIGTLAPSLGQGQQFEIQAQSIEVVGWVEDPETYPIQPKQHSLEF
HHHHHHHHHCCCEEEEEEHHCCCCCCCCEEEEEEEEEEEEEEECCCCCCCCCCHHHHHHH
LREVAHLRPRTNLFGAVARIRHCLSQAVHRFFHENGYYWITTPIITTSDAEGAGQMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECEEEECCCCCCCCEEEEE
TLDLVNLPRTETGGIDFSHDFFGKETFLTVSGQLNVEAYALALSKVYTFGPTFRAENSHT
EEHEECCCCCCCCCCCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
PRHLAEFWMIEPEIAFADLAEDARVAEQFLKFLFKTVLEERDDDLAFITERVEKTTISKL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
EGFINSPFERIEYTDAIKLLERSGKKFDFPVEWGLDLQTEHERWLTEKHIGRPVVVTNYP
HHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCH
EHIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLEMLDIRMAQFGLDPAHYQWY
HHHHHHHEEECCCCCEEEEHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
RDFRRYGSVPHAGFGLGFERLVVYVCGLSNIRDAIPYPRAPGSAEF
HHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TVASVEQMFSGKIQVGSEVTVRGWVRTRRDSKAGLSFVSVSDGSCFAAIQVVTPAHLPN
CHHHHHHHHCCCEEECCEEEEEHHHHHCCCCCCCEEEEEECCCCEEEEEEEECCCCCCC
YETEVRKLTTGCAVIVIGTLAPSLGQGQQFEIQAQSIEVVGWVEDPETYPIQPKQHSLEF
HHHHHHHHHCCCEEEEEEHHCCCCCCCCEEEEEEEEEEEEEEECCCCCCCCCCHHHHHHH
LREVAHLRPRTNLFGAVARIRHCLSQAVHRFFHENGYYWITTPIITTSDAEGAGQMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECEEEECCCCCCCCEEEEE
TLDLVNLPRTETGGIDFSHDFFGKETFLTVSGQLNVEAYALALSKVYTFGPTFRAENSHT
EEHEECCCCCCCCCCCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
PRHLAEFWMIEPEIAFADLAEDARVAEQFLKFLFKTVLEERDDDLAFITERVEKTTISKL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
EGFINSPFERIEYTDAIKLLERSGKKFDFPVEWGLDLQTEHERWLTEKHIGRPVVVTNYP
HHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCH
EHIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLEMLDIRMAQFGLDPAHYQWY
HHHHHHHEEECCCCCEEEEHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
RDFRRYGSVPHAGFGLGFERLVVYVCGLSNIRDAIPYPRAPGSAEF
HHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]