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The map label for this gene is pilC [H]

Identifier: 182682542

GI number: 182682542

Start: 2270954

End: 2272345

Strand: Reverse

Name: pilC [H]

Synonym: XfasM23_2030

Alternate gene names: 182682542

Gene position: 2272345-2270954 (Counterclockwise)

Preceding gene: 182682544

Following gene: 182682541

Centisome position: 89.61

GC content: 49.93

Gene sequence:

>1392_bases
ATGGGGGTGTTGAATGAAGAGCGCTTATGGGTGTGGTGCACGAGCTTTTTAGATTTTGCTGCTAGGGTTTCAGGAACAAG
TTACCATGCGTCATCGGTCCGCTTGGGGACGGTGGATGGGAGAACAGCATTGATATTTGCAACACGTACTGCGGTAAATG
CTTCGCGTGCTGGGAATACCAGCCCGCCGTTGACTTCGTTTCTTTGGGAAGGGACGGATAAGCGCGGTGTCAAAATCAAG
GGGGAACAGACAGCACGCACGGCGAACTTGTTGCGTGCTGAGCTACGTCGTCAAGGCATCACGCCTCTTGTGGTTAAGCC
TAGGCCTAAGCCGCTGTTTGGTCAGGCAGGGAAGCGGATCACTCCGAAGGACATTGCCTTTTTTAGTCGCCAGATGGCGA
CGATGATGAAAGCCGGTGTCCCCATTGTCGGGGCGTTGGATATTTTGGCCAACGGTCAGAAGAATCCGCGTATGCGTACG
ATGGTCAATCAAATTAAAAATGATATTGAAGGCGGCTCCTCGCTGTATGAGTCAATCAGCAAGCACCCTGTATATTTCGA
TGAGCTTTATCGCAATCTGGTCAGGGCTGGTGAGCGCGCGGGCGTGCTGGAGACGGTGCTTGATACGGTTGCTAGTTATA
AGGAGAACATTGAGGCTCTGAAGGGAAAAATTCGCAAGGCGTTGTTTTATCCTGTTGCTATTGTCGCGGTTGCTCTCATT
GTTAGTTCGATTTTATTGATATACGTGGTGCCGCAGTTCGAGGATGTGTTCAAAGGATTCGGAGCGGAATTGCCTGCATT
CACTCAGATGATTGTCAATTTTTCCAACTTTATGCAGCGGTGGTGGTGGGCCATGTTGGCTCTGCTGATTGTTGTTATCG
GTGGTGGTTTGTTTACTTACAAGCGCTCTGAATCCATGCAACATCTGTTGGATAGGTTGGTGTTGAAGTTCCCGGTGATC
GGGGCAATTATGCACAATAGCGCGCTTGCTCGGTTCTCGCGAACAACAGCTGTTACTTTCCGTGCAGGGGTGCCACTGGT
AGAGGCATTGGGTATCGTTGCTGGGGCAACCGGCAATAAGGTTTATTCGGATGCTGTGTTCCGCATGCGTGATGATGTTT
CAGTTGGCTATTCTATAAATATGTCAATGAGGCAAGTTGGTATCTTCCCTCATATGGTGGTGCAGATGGCTTCCATCGGT
GAGGAAGCCGGTGCTCTGGACGCGATGCTGTTTAAAGTCGCTGAGTACTATGAACAGGAAGTCAGTAACGCGGTCGATGG
ACTCAGCAGTTTGCTGGAACCGCTGATCATGGTCTTTATTGGTGTTATCGTCGGCGGCATGGTCATTGCTATGTATTTGC
CGATCTTTAAGCTTGCTTCTGTCGTTGGATAA

Upstream 100 bases:

>100_bases
ATGCCCGAATGAATAAACTTTGGAAGGGTTTTATTTAATAATTGCGATCCATTCTTCCAGAAGTCGTAAATGGTCAATAT
ATGTCATTGAATGTCACTTT

Downstream 100 bases:

>100_bases
AACGTTATGGCATTTCTTGATCAGCACCCCGGACTCGGCTATCCCCTTGCGTCCGGTTTGGGGTTGTTGCTTGGTAGTTT
TCTCAATGTGGTGATCCTGC

Product: type II secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MGVLNEERLWVWCTSFLDFAARVSGTSYHASSVRLGTVDGRTALIFATRTAVNASRAGNTSPPLTSFLWEGTDKRGVKIK
GEQTARTANLLRAELRRQGITPLVVKPRPKPLFGQAGKRITPKDIAFFSRQMATMMKAGVPIVGALDILANGQKNPRMRT
MVNQIKNDIEGGSSLYESISKHPVYFDELYRNLVRAGERAGVLETVLDTVASYKENIEALKGKIRKALFYPVAIVAVALI
VSSILLIYVVPQFEDVFKGFGAELPAFTQMIVNFSNFMQRWWWAMLALLIVVIGGGLFTYKRSESMQHLLDRLVLKFPVI
GAIMHNSALARFSRTTAVTFRAGVPLVEALGIVAGATGNKVYSDAVFRMRDDVSVGYSINMSMRQVGIFPHMVVQMASIG
EEAGALDAMLFKVAEYYEQEVSNAVDGLSSLLEPLIMVFIGVIVGGMVIAMYLPIFKLASVVG

Sequences:

>Translated_463_residues
MGVLNEERLWVWCTSFLDFAARVSGTSYHASSVRLGTVDGRTALIFATRTAVNASRAGNTSPPLTSFLWEGTDKRGVKIK
GEQTARTANLLRAELRRQGITPLVVKPRPKPLFGQAGKRITPKDIAFFSRQMATMMKAGVPIVGALDILANGQKNPRMRT
MVNQIKNDIEGGSSLYESISKHPVYFDELYRNLVRAGERAGVLETVLDTVASYKENIEALKGKIRKALFYPVAIVAVALI
VSSILLIYVVPQFEDVFKGFGAELPAFTQMIVNFSNFMQRWWWAMLALLIVVIGGGLFTYKRSESMQHLLDRLVLKFPVI
GAIMHNSALARFSRTTAVTFRAGVPLVEALGIVAGATGNKVYSDAVFRMRDDVSVGYSINMSMRQVGIFPHMVVQMASIG
EEAGALDAMLFKVAEYYEQEVSNAVDGLSSLLEPLIMVFIGVIVGGMVIAMYLPIFKLASVVG
>Mature_462_residues
GVLNEERLWVWCTSFLDFAARVSGTSYHASSVRLGTVDGRTALIFATRTAVNASRAGNTSPPLTSFLWEGTDKRGVKIKG
EQTARTANLLRAELRRQGITPLVVKPRPKPLFGQAGKRITPKDIAFFSRQMATMMKAGVPIVGALDILANGQKNPRMRTM
VNQIKNDIEGGSSLYESISKHPVYFDELYRNLVRAGERAGVLETVLDTVASYKENIEALKGKIRKALFYPVAIVAVALIV
SSILLIYVVPQFEDVFKGFGAELPAFTQMIVNFSNFMQRWWWAMLALLIVVIGGGLFTYKRSESMQHLLDRLVLKFPVIG
AIMHNSALARFSRTTAVTFRAGVPLVEALGIVAGATGNKVYSDAVFRMRDDVSVGYSINMSMRQVGIFPHMVVQMASIGE
EAGALDAMLFKVAEYYEQEVSNAVDGLSSLLEPLIMVFIGVIVGGMVIAMYLPIFKLASVVG

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=398, Percent_Identity=28.1407035175879, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1786295, Length=395, Percent_Identity=27.5949367088608, Blast_Score=161, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 50836; Mature: 50705

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVLNEERLWVWCTSFLDFAARVSGTSYHASSVRLGTVDGRTALIFATRTAVNASRAGNT
CCCCCCCHHHHHHHHHHHHHHHHCCCCEECCCEEEEECCCCEEEEEEEHHHHHHHCCCCC
SPPLTSFLWEGTDKRGVKIKGEQTARTANLLRAELRRQGITPLVVKPRPKPLFGQAGKRI
CCCHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCC
TPKDIAFFSRQMATMMKAGVPIVGALDILANGQKNPRMRTMVNQIKNDIEGGSSLYESIS
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
KHPVYFDELYRNLVRAGERAGVLETVLDTVASYKENIEALKGKIRKALFYPVAIVAVALI
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSSILLIYVVPQFEDVFKGFGAELPAFTQMIVNFSNFMQRWWWAMLALLIVVIGGGLFTY
HHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
KRSESMQHLLDRLVLKFPVIGAIMHNSALARFSRTTAVTFRAGVPLVEALGIVAGATGNK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHCCCCCH
VYSDAVFRMRDDVSVGYSINMSMRQVGIFPHMVVQMASIGEEAGALDAMLFKVAEYYEQE
HHHHHHHHHHCCCCCCEEECCHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
VSNAVDGLSSLLEPLIMVFIGVIVGGMVIAMYLPIFKLASVVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GVLNEERLWVWCTSFLDFAARVSGTSYHASSVRLGTVDGRTALIFATRTAVNASRAGNT
CCCCCCHHHHHHHHHHHHHHHHCCCCEECCCEEEEECCCCEEEEEEEHHHHHHHCCCCC
SPPLTSFLWEGTDKRGVKIKGEQTARTANLLRAELRRQGITPLVVKPRPKPLFGQAGKRI
CCCHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCC
TPKDIAFFSRQMATMMKAGVPIVGALDILANGQKNPRMRTMVNQIKNDIEGGSSLYESIS
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
KHPVYFDELYRNLVRAGERAGVLETVLDTVASYKENIEALKGKIRKALFYPVAIVAVALI
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSSILLIYVVPQFEDVFKGFGAELPAFTQMIVNFSNFMQRWWWAMLALLIVVIGGGLFTY
HHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
KRSESMQHLLDRLVLKFPVIGAIMHNSALARFSRTTAVTFRAGVPLVEALGIVAGATGNK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHCCCCCH
VYSDAVFRMRDDVSVGYSINMSMRQVGIFPHMVVQMASIGEEAGALDAMLFKVAEYYEQE
HHHHHHHHHHCCCCCCEEECCHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
VSNAVDGLSSLLEPLIMVFIGVIVGGMVIAMYLPIFKLASVVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]