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The map label for this gene is coaE

Identifier: 182682540

GI number: 182682540

Start: 2269449

End: 2270072

Strand: Reverse

Name: coaE

Synonym: XfasM23_2028

Alternate gene names: 182682540

Gene position: 2270072-2269449 (Counterclockwise)

Preceding gene: 182682541

Following gene: 182682534

Centisome position: 89.52

GC content: 53.69

Gene sequence:

>624_bases
ATGAGTGTCTATGCGGTTGGTCTCACTGGAGGGGTCGCTTGCGGTAAGAGCTTGCTGGCGCAGCTGTTCGAGGCGTTAAA
CACGACGGTTGTTGATGCAGATACAATTGCCCGCCAAGTGGTTGAGCCTGGTCCAGTTCTCAATTGCATCGTTGCTAGGT
TTGGTAGCAAGATTTTGCGGGCTGATGGTTGTCTTGATCGTCGTTTTTTGCGGCAACGTGTATTTGCCGATGTGGCCGAA
CGAAAGGCGTTGGAGGCTATTGTCCATCCGGTGATCCGAGCTAGGTTGAAGCAGGCGGCGGCGGCGGCGGCAGGTCCATA
TGTGCTAGTCGTCATTCCACTTTTGGCCGAGGCTGGTGGTCGCATTGGATACCCTTGGTTGCAGCGCATTCTTGTCGTGG
ATGCTATACCGGAAGTACAACACGCACGACTGATGCAGCGTGATTCAATTGACGCTGAGCAGGCTTCCTTGATGATCGCG
GCCCAGATTGGCCGCAAAGAGCGCTTAGCTATAGCCGACGATATTGTGTTTAACGATGGAGATCCCGCGCATTTGGGCGG
GCAGGTATGCAATTTGGACGCGCGCTATCGCGCTCTTGCTTCTGTTTTTTCTGATGTTGATTAG

Upstream 100 bases:

>100_bases
GACCTTATCTGGCAGTTGGTGGATGGATCGTGTTCTTTTTCGGCGATCAGATCATCCATGCTTATCTGGAGCTATTAAGT
ATCGGGTGAGGTTGGAGTTG

Downstream 100 bases:

>100_bases
TATCAATTGTTGGCATTACCGAGAGACATCAATTCATCATTGTGACACTTAAATAGTGTACGGTGGTGGATGTTATTTGC
GGTTGTTATCTGCAAGAGTA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSVYAVGLTGGVACGKSLLAQLFEALNTTVVDADTIARQVVEPGPVLNCIVARFGSKILRADGCLDRRFLRQRVFADVAE
RKALEAIVHPVIRARLKQAAAAAAGPYVLVVIPLLAEAGGRIGYPWLQRILVVDAIPEVQHARLMQRDSIDAEQASLMIA
AQIGRKERLAIADDIVFNDGDPAHLGGQVCNLDARYRALASVFSDVD

Sequences:

>Translated_207_residues
MSVYAVGLTGGVACGKSLLAQLFEALNTTVVDADTIARQVVEPGPVLNCIVARFGSKILRADGCLDRRFLRQRVFADVAE
RKALEAIVHPVIRARLKQAAAAAAGPYVLVVIPLLAEAGGRIGYPWLQRILVVDAIPEVQHARLMQRDSIDAEQASLMIA
AQIGRKERLAIADDIVFNDGDPAHLGGQVCNLDARYRALASVFSDVD
>Mature_206_residues
SVYAVGLTGGVACGKSLLAQLFEALNTTVVDADTIARQVVEPGPVLNCIVARFGSKILRADGCLDRRFLRQRVFADVAER
KALEAIVHPVIRARLKQAAAAAAGPYVLVVIPLLAEAGGRIGYPWLQRILVVDAIPEVQHARLMQRDSIDAEQASLMIAA
QIGRKERLAIADDIVFNDGDPAHLGGQVCNLDARYRALASVFSDVD

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=183, Percent_Identity=34.9726775956284, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI191252795, Length=183, Percent_Identity=34.9726775956284, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI110227607, Length=167, Percent_Identity=32.3353293413174, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI110227605, Length=172, Percent_Identity=31.9767441860465, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI110227603, Length=172, Percent_Identity=31.9767441860465, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI110227601, Length=172, Percent_Identity=31.9767441860465, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI205277394, Length=172, Percent_Identity=31.9767441860465, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1786292, Length=201, Percent_Identity=46.2686567164179, Blast_Score=171, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17554944, Length=196, Percent_Identity=33.6734693877551, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6320402, Length=197, Percent_Identity=37.0558375634518, Blast_Score=88, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24644728, Length=182, Percent_Identity=28.021978021978, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24658602, Length=184, Percent_Identity=31.5217391304348, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22253; Mature: 22122

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVYAVGLTGGVACGKSLLAQLFEALNTTVVDADTIARQVVEPGPVLNCIVARFGSKILR
CCEEEEECCCHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ADGCLDRRFLRQRVFADVAERKALEAIVHPVIRARLKQAAAAAAGPYVLVVIPLLAEAGG
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
RIGYPWLQRILVVDAIPEVQHARLMQRDSIDAEQASLMIAAQIGRKERLAIADDIVFNDG
CCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHEEECCC
DPAHLGGQVCNLDARYRALASVFSDVD
CCHHHCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVYAVGLTGGVACGKSLLAQLFEALNTTVVDADTIARQVVEPGPVLNCIVARFGSKILR
CEEEEECCCHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ADGCLDRRFLRQRVFADVAERKALEAIVHPVIRARLKQAAAAAAGPYVLVVIPLLAEAGG
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
RIGYPWLQRILVVDAIPEVQHARLMQRDSIDAEQASLMIAAQIGRKERLAIADDIVFNDG
CCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHEEECCC
DPAHLGGQVCNLDARYRALASVFSDVD
CCHHHCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]