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The map label for this gene is infC

Identifier: 182682532

GI number: 182682532

Start: 2260767

End: 2261210

Strand: Reverse

Name: infC

Synonym: XfasM23_2019

Alternate gene names: 182682532

Gene position: 2261210-2260767 (Counterclockwise)

Preceding gene: 182682533

Following gene: 182682531

Centisome position: 89.18

GC content: 47.97

Gene sequence:

>444_bases
ATGATTGGCGTGTTGTCGCGTGACGAAGCGCTTGCCATGGCCGAAAAAGAAGGATTGGATCTGGTCGAGATACAGCCTCA
AGCTGATCCGCCGGTTTGTAAGGTTATGAACTTTGGCAAGTTCAAGTTCGAGCAACAAAAGAAGGCGAACGAAGCTAAAA
AGAAGACTAAACAAGTCGAGATCAAGGAACTTAAGTTCCGCCCAGTCACGGACGAGGGTGACTACCAGATCAAGCTGCGT
AACATGCGTCGTTTTCTGGAAGAGGGTGATAAAGTTAAGATTAACATTCGCTTCCGTGGCCGTGAGATGAGCCATCAAGA
ATTAGGTCGACAGATGGCAGCGCGTATTGAAATGGATCTTGGTGATGATGTCGTTATTGAATCCCGTCCCCGCTTAGAAG
GGCGACAGATGGTGATGATGGTTGCGCCGAGGAAAAAAAGCTAA

Upstream 100 bases:

>100_bases
CCTTGGAGATTGCAATATCAGTACCTCTGACAACAAACAGAACCGTAAGAACCATGAAATCCGGGTACCACGTGTACGCG
TGATTGGTAGTGACGGAGAA

Downstream 100 bases:

>100_bases
GACGTCTTTCATTTAATTTTTTATCTTTGTACCGAAGCATCTCATTTACAAAATGTTTTGTCTCCTGGCATACTAGCAGA
TCAGCTTCTTGGAGCTGGTT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MIGVLSRDEALAMAEKEGLDLVEIQPQADPPVCKVMNFGKFKFEQQKKANEAKKKTKQVEIKELKFRPVTDEGDYQIKLR
NMRRFLEEGDKVKINIRFRGREMSHQELGRQMAARIEMDLGDDVVIESRPRLEGRQMVMMVAPRKKS

Sequences:

>Translated_147_residues
MIGVLSRDEALAMAEKEGLDLVEIQPQADPPVCKVMNFGKFKFEQQKKANEAKKKTKQVEIKELKFRPVTDEGDYQIKLR
NMRRFLEEGDKVKINIRFRGREMSHQELGRQMAARIEMDLGDDVVIESRPRLEGRQMVMMVAPRKKS
>Mature_147_residues
MIGVLSRDEALAMAEKEGLDLVEIQPQADPPVCKVMNFGKFKFEQQKKANEAKKKTKQVEIKELKFRPVTDEGDYQIKLR
NMRRFLEEGDKVKINIRFRGREMSHQELGRQMAARIEMDLGDDVVIESRPRLEGRQMVMMVAPRKKS

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=146, Percent_Identity=56.8493150684932, Blast_Score=164, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 17107; Mature: 17107

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.8 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
6.8 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGVLSRDEALAMAEKEGLDLVEIQPQADPPVCKVMNFGKFKFEQQKKANEAKKKTKQVE
CCCCCCCCHHHHHHHHCCCEEEEECCCCCCCHHHHCCCCCCEEHHHHHHHHHHHHHHCCE
IKELKFRPVTDEGDYQIKLRNMRRFLEEGDKVKINIRFRGREMSHQELGRQMAARIEMDL
EEHEEEEECCCCCCEEEEHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCC
GDDVVIESRPRLEGRQMVMMVAPRKKS
CCCEEECCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MIGVLSRDEALAMAEKEGLDLVEIQPQADPPVCKVMNFGKFKFEQQKKANEAKKKTKQVE
CCCCCCCCHHHHHHHHCCCEEEEECCCCCCCHHHHCCCCCCEEHHHHHHHHHHHHHHCCE
IKELKFRPVTDEGDYQIKLRNMRRFLEEGDKVKINIRFRGREMSHQELGRQMAARIEMDL
EEHEEEEECCCCCCEEEEHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCC
GDDVVIESRPRLEGRQMVMMVAPRKKS
CCCEEECCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]