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The map label for this gene is rnd [H]

Identifier: 182682522

GI number: 182682522

Start: 2250152

End: 2251240

Strand: Direct

Name: rnd [H]

Synonym: XfasM23_2009

Alternate gene names: 182682522

Gene position: 2250152-2251240 (Clockwise)

Preceding gene: 182682519

Following gene: 182682523

Centisome position: 88.74

GC content: 52.34

Gene sequence:

>1089_bases
GTGCCGCATTGGATCCAGCACCCCGACACTCTCGCTACCTGGTGGGATCGAAAACCAACCCGAATCGGTATGGATACCGA
GTTCATCCGAGAAGGCACTTTTTGGCCAGAATTAGCGCTGGTACAGATCGCAATTGGAGATGAAATATTACTGGTGGACC
CACTGGTCCCCGGGATGACCGACGCGCTGGGACTCTGGTTGGCCGCTCCGAATGTCATCAAAATTATGCACAGCGCCAGT
GAGGACTTAATTGCATTCAAATATGCCTGTGGTGTGCTACCACGGCCGCTGTTTGATACCCAAATTGGGGCTGCATTGAC
GGGCTTGGGTGGTGGGATGGGTTACCAGAAGTTGGTGGCCAAGGTTACCAATGTGGAATTGGGAAAAGGCGAAACACGCT
CAGACTGGATGCACCGACCACTCACGCCAGCGCAACTAGACTACGCGGCTAACGATGTCCGGTATTTATTTGCATTGCAT
GACACGCTCACAGAACGGTTAGCAGAAATGAGCCGCAGTGCTTGGTTGGAAGAGGACTGCACACGATTGACCGACAATAT
CGAACAAAACGAGAACGAACGCTGGCCGCATCTGGCAATACGTTCAGCACAACTTCTTGACGCTCCAGCACAGTACCGCC
TGCTGCGCTTATTGCGCTGGCGGGAAACATCAGCACGCTCCAGCAACAAACCACGCAACTGGATACTGAACAACGAACTG
GCGAGCATTCTGGCACGGTTCCCTCCTCCCAATATGACCGAACTGCGATACCAGCTTAAAAAGTTCAATAAATCCTGGGA
CCCGCTCGCCACTCAAATACTGGAAGCGCTACAGACTCCTCTTGCCGATGAAGCGCAAGCGCCATTGGTAACTGCACCCA
GCGATGCAGACAAAGCGTTGCTCAAGCAACTACAGAAAATCGTCGCCGAATGTAGCTATGATCTAGGTTTACCTGAGGGT
ATCCTAGCGTCGCGTCGTCATTTAGAAGCTCTCATCGAACAACGCCGATGGCCAAACTCACTCGGCCAATGGCGCCGCTC
TCTGCTCGAAACGCAGTTACAACCATTATTATCTATGTCAGATACCTAA

Upstream 100 bases:

>100_bases
CCAGCGATGCGCAAATACGCTTCCTCCCAAGAAAGCACCACGGCAAACCTTAGGCTATTCTTCTCGACTCAAACAATCCT
AGCTCAATCACGGAAATCAC

Downstream 100 bases:

>100_bases
CGTTTCATTCCGAGGAATGAAGCTGTATTACACTTCGCATCCTGGCATTTGGCTTGGAAGGGGCTGGGATTGCGGTTAAG
ACAATAGAAATATCCTTTCC

Product: ribonuclease D

Products: NA

Alternate protein names: RNase D [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MPHWIQHPDTLATWWDRKPTRIGMDTEFIREGTFWPELALVQIAIGDEILLVDPLVPGMTDALGLWLAAPNVIKIMHSAS
EDLIAFKYACGVLPRPLFDTQIGAALTGLGGGMGYQKLVAKVTNVELGKGETRSDWMHRPLTPAQLDYAANDVRYLFALH
DTLTERLAEMSRSAWLEEDCTRLTDNIEQNENERWPHLAIRSAQLLDAPAQYRLLRLLRWRETSARSSNKPRNWILNNEL
ASILARFPPPNMTELRYQLKKFNKSWDPLATQILEALQTPLADEAQAPLVTAPSDADKALLKQLQKIVAECSYDLGLPEG
ILASRRHLEALIEQRRWPNSLGQWRRSLLETQLQPLLSMSDT

Sequences:

>Translated_362_residues
MPHWIQHPDTLATWWDRKPTRIGMDTEFIREGTFWPELALVQIAIGDEILLVDPLVPGMTDALGLWLAAPNVIKIMHSAS
EDLIAFKYACGVLPRPLFDTQIGAALTGLGGGMGYQKLVAKVTNVELGKGETRSDWMHRPLTPAQLDYAANDVRYLFALH
DTLTERLAEMSRSAWLEEDCTRLTDNIEQNENERWPHLAIRSAQLLDAPAQYRLLRLLRWRETSARSSNKPRNWILNNEL
ASILARFPPPNMTELRYQLKKFNKSWDPLATQILEALQTPLADEAQAPLVTAPSDADKALLKQLQKIVAECSYDLGLPEG
ILASRRHLEALIEQRRWPNSLGQWRRSLLETQLQPLLSMSDT
>Mature_361_residues
PHWIQHPDTLATWWDRKPTRIGMDTEFIREGTFWPELALVQIAIGDEILLVDPLVPGMTDALGLWLAAPNVIKIMHSASE
DLIAFKYACGVLPRPLFDTQIGAALTGLGGGMGYQKLVAKVTNVELGKGETRSDWMHRPLTPAQLDYAANDVRYLFALHD
TLTERLAEMSRSAWLEEDCTRLTDNIEQNENERWPHLAIRSAQLLDAPAQYRLLRLLRWRETSARSSNKPRNWILNNELA
SILARFPPPNMTELRYQLKKFNKSWDPLATQILEALQTPLADEAQAPLVTAPSDADKALLKQLQKIVAECSYDLGLPEGI
LASRRHLEALIEQRRWPNSLGQWRRSLLETQLQPLLSMSDT

Specific function: Cleaves multimeric tRNA precursor at the spacer region. Contribute to the 3' maturation of several stable RNAs [H]

COG id: COG0349

COG function: function code J; Ribonuclease D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Escherichia coli, GI1788105, Length=365, Percent_Identity=30.4109589041096, Blast_Score=132, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17531757, Length=210, Percent_Identity=26.1904761904762, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR002121
- InterPro:   IPR010997
- InterPro:   IPR006292
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF00570 HRDC [H]

EC number: =3.1.13.5 [H]

Molecular weight: Translated: 41097; Mature: 40965

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHWIQHPDTLATWWDRKPTRIGMDTEFIREGTFWPELALVQIAIGDEILLVDPLVPGMT
CCCCCCCCCHHHHHHCCCCCEECCCHHHHHCCCCCCHHEEEEEEECCEEEEECCCCCCHH
DALGLWLAAPNVIKIMHSASEDLIAFKYACGVLPRPLFDTQIGAALTGLGGGMGYQKLVA
HHHHHHHHCCHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
KVTNVELGKGETRSDWMHRPLTPAQLDYAANDVRYLFALHDTLTERLAEMSRSAWLEEDC
HHHHCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRLTDNIEQNENERWPHLAIRSAQLLDAPAQYRLLRLLRWRETSARSSNKPRNWILNNEL
HHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHH
ASILARFPPPNMTELRYQLKKFNKSWDPLATQILEALQTPLADEAQAPLVTAPSDADKAL
HHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHH
LKQLQKIVAECSYDLGLPEGILASRRHLEALIEQRRWPNSLGQWRRSLLETQLQPLLSMS
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
DT
CC
>Mature Secondary Structure 
PHWIQHPDTLATWWDRKPTRIGMDTEFIREGTFWPELALVQIAIGDEILLVDPLVPGMT
CCCCCCCCHHHHHHCCCCCEECCCHHHHHCCCCCCHHEEEEEEECCEEEEECCCCCCHH
DALGLWLAAPNVIKIMHSASEDLIAFKYACGVLPRPLFDTQIGAALTGLGGGMGYQKLVA
HHHHHHHHCCHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
KVTNVELGKGETRSDWMHRPLTPAQLDYAANDVRYLFALHDTLTERLAEMSRSAWLEEDC
HHHHCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRLTDNIEQNENERWPHLAIRSAQLLDAPAQYRLLRLLRWRETSARSSNKPRNWILNNEL
HHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHH
ASILARFPPPNMTELRYQLKKFNKSWDPLATQILEALQTPLADEAQAPLVTAPSDADKAL
HHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHH
LKQLQKIVAECSYDLGLPEGILASRRHLEALIEQRRWPNSLGQWRRSLLETQLQPLLSMS
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
DT
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]