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The map label for this gene is murG

Identifier: 182682482

GI number: 182682482

Start: 2208976

End: 2210079

Strand: Reverse

Name: murG

Synonym: XfasM23_1969

Alternate gene names: 182682482

Gene position: 2210079-2208976 (Counterclockwise)

Preceding gene: 182682483

Following gene: 182682481

Centisome position: 87.16

GC content: 54.08

Gene sequence:

>1104_bases
ATGAGCATAGTGGTCCAATCTGCGGTGACGCACTTTCGCCCCGTCATGATTTTGGCTGGTGGTACCGGTGGTCATATTTT
CCCTGGTTTGGCGGTGGCAGGTGTGTTGCGTGCCCGTGGTGTACCAGTGGTATGGCTGGGCGCAGCCGGAAAAATGGAAA
CGCATTTAGTACCAAAGCACGGTATTGAAATACAGACCATTGCCGTTTCCGGTGTGCGTGGTCATGGCATGTTGGCTTTG
CTTGGTGCGCCTGTGCGTGTGTTACCTGCAATTTTTGCTGCCATGCGGGTATTACGTCGGTATCGCCCACGTGTGGTGGT
CAGTTTTGGTGGTTTCGCGGCAGGTCCTGGTGGTATTGCAGCACGTTTGATGGGTCTGCCTCTGATTGTGCACGAGCAGA
ATCGTGCGCCTGGAATGACTAATAGGGTTTTGGCACGTGTTGCGAGACGTGTTCTATCTGGTTTTCCGGGCAGTTTTGTT
GCTGAGGAGGTGGTGGGGAATCCAGTGCGTAAGGACATTGCTGCGCTGCCCGCACCAGGAGTACGTTTTGCTGGCCGCAG
TGGTCCGGTGCGCTTGTTAGTGCTTGGGGGCAGTCAGGGGGCACGTGTAATGAATAATGCGTTGCCGGTGGTGTTGCGGG
TGTTGTCTGATTCTGATGTGGCTGTGGAGGTGCGTCATCAGTGTGGCGAAGCGCTGCGTGCTGAAACGGAGGGTGCCTAT
GCATATGCAGGTGTGGCTGCGCGTGTTGAACCGTTTATTAGTGATATGGCTGCAGCGTATTCCTGGGCCGATTTAGTGGT
GTGTCGTGCCGGTGCCTCAACGTTGGCTGAGTTGTGTGCAGCCGGTGTTGGGAGTGTGTTGATACCTTTTCCTGCGGCGG
TGGATGATCACCAGAGGCGCAATGCGGAATATCTGGTTGCTGCTGGTGCTGCGTTGTTGTTGCAGCAGCAGGACCGTGCA
TTTTATGTCTATCTAGAGTCGGTGTTGCGTGATTTGTTGTCTAATCCAATGCGTCGCTTGGCGATGGCTGAGGCTGCACG
TGGATTGGCTAAATCTGATGCTGCCGAGTGTATTGCTGAAATTATTCTTAAGGAATCGATATGA

Upstream 100 bases:

>100_bases
TGTTGCTGCACGAGGTTGTTGGTGCTCCATTGGCCGCATCGCAGCAGGTGGGGGGAAGTCAGATGCGCTCCCGCGTGGCA
TCGGTGTTTGGGAAGGTGCT

Downstream 100 bases:

>100_bases
GGCGTGGAGTCGTTTCCAAAATGGTTGGGTGTCGTGCTCAAAGTGAGTGCTGTTTGTGATTCGTCGTCTTCAAGACAATG
GCGATTTGATCCGTGCTTTC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSIVVQSAVTHFRPVMILAGGTGGHIFPGLAVAGVLRARGVPVVWLGAAGKMETHLVPKHGIEIQTIAVSGVRGHGMLAL
LGAPVRVLPAIFAAMRVLRRYRPRVVVSFGGFAAGPGGIAARLMGLPLIVHEQNRAPGMTNRVLARVARRVLSGFPGSFV
AEEVVGNPVRKDIAALPAPGVRFAGRSGPVRLLVLGGSQGARVMNNALPVVLRVLSDSDVAVEVRHQCGEALRAETEGAY
AYAGVAARVEPFISDMAAAYSWADLVVCRAGASTLAELCAAGVGSVLIPFPAAVDDHQRRNAEYLVAAGAALLLQQQDRA
FYVYLESVLRDLLSNPMRRLAMAEAARGLAKSDAAECIAEIILKESI

Sequences:

>Translated_367_residues
MSIVVQSAVTHFRPVMILAGGTGGHIFPGLAVAGVLRARGVPVVWLGAAGKMETHLVPKHGIEIQTIAVSGVRGHGMLAL
LGAPVRVLPAIFAAMRVLRRYRPRVVVSFGGFAAGPGGIAARLMGLPLIVHEQNRAPGMTNRVLARVARRVLSGFPGSFV
AEEVVGNPVRKDIAALPAPGVRFAGRSGPVRLLVLGGSQGARVMNNALPVVLRVLSDSDVAVEVRHQCGEALRAETEGAY
AYAGVAARVEPFISDMAAAYSWADLVVCRAGASTLAELCAAGVGSVLIPFPAAVDDHQRRNAEYLVAAGAALLLQQQDRA
FYVYLESVLRDLLSNPMRRLAMAEAARGLAKSDAAECIAEIILKESI
>Mature_366_residues
SIVVQSAVTHFRPVMILAGGTGGHIFPGLAVAGVLRARGVPVVWLGAAGKMETHLVPKHGIEIQTIAVSGVRGHGMLALL
GAPVRVLPAIFAAMRVLRRYRPRVVVSFGGFAAGPGGIAARLMGLPLIVHEQNRAPGMTNRVLARVARRVLSGFPGSFVA
EEVVGNPVRKDIAALPAPGVRFAGRSGPVRLLVLGGSQGARVMNNALPVVLRVLSDSDVAVEVRHQCGEALRAETEGAYA
YAGVAARVEPFISDMAAAYSWADLVVCRAGASTLAELCAAGVGSVLIPFPAAVDDHQRRNAEYLVAAGAALLLQQQDRAF
YVYLESVLRDLLSNPMRRLAMAEAARGLAKSDAAECIAEIILKESI

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=350, Percent_Identity=48.8571428571429, Blast_Score=310, Evalue=1e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_XYLF2 (B2I9B3)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001830642.1
- GeneID:   6203323
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_1969
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38519; Mature: 38387

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVVQSAVTHFRPVMILAGGTGGHIFPGLAVAGVLRARGVPVVWLGAAGKMETHLVPKH
CCEEHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCEEECCCC
GIEIQTIAVSGVRGHGMLALLGAPVRVLPAIFAAMRVLRRYRPRVVVSFGGFAAGPGGIA
CCEEEEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHH
ARLMGLPLIVHEQNRAPGMTNRVLARVARRVLSGFPGSFVAEEVVGNPVRKDIAALPAPG
HHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHCCCCC
VRFAGRSGPVRLLVLGGSQGARVMNNALPVVLRVLSDSDVAVEVRHQCGEALRAETEGAY
CEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCE
AYAGVAARVEPFISDMAAAYSWADLVVCRAGASTLAELCAAGVGSVLIPFPAAVDDHQRR
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCCCCCCCHHHC
NAEYLVAAGAALLLQQQDRAFYVYLESVLRDLLSNPMRRLAMAEAARGLAKSDAAECIAE
CCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
IILKESI
HHHHCCC
>Mature Secondary Structure 
SIVVQSAVTHFRPVMILAGGTGGHIFPGLAVAGVLRARGVPVVWLGAAGKMETHLVPKH
CEEHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCEEECCCC
GIEIQTIAVSGVRGHGMLALLGAPVRVLPAIFAAMRVLRRYRPRVVVSFGGFAAGPGGIA
CCEEEEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHH
ARLMGLPLIVHEQNRAPGMTNRVLARVARRVLSGFPGSFVAEEVVGNPVRKDIAALPAPG
HHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHCCCCC
VRFAGRSGPVRLLVLGGSQGARVMNNALPVVLRVLSDSDVAVEVRHQCGEALRAETEGAY
CEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCE
AYAGVAARVEPFISDMAAAYSWADLVVCRAGASTLAELCAAGVGSVLIPFPAAVDDHQRR
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCCCCCCCHHHC
NAEYLVAAGAALLLQQQDRAFYVYLESVLRDLLSNPMRRLAMAEAARGLAKSDAAECIAE
CCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
IILKESI
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA