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The map label for this gene is msrB

Identifier: 182682439

GI number: 182682439

Start: 2146234

End: 2146701

Strand: Direct

Name: msrB

Synonym: XfasM23_1925

Alternate gene names: 182682439

Gene position: 2146234-2146701 (Clockwise)

Preceding gene: 182682435

Following gene: 182682440

Centisome position: 84.64

GC content: 57.48

Gene sequence:

>468_bases
ATGAATGTCACTTTCGACCTAACCCCGCCATCCCCATCGCAACGTGAAGCACTGATTGCCACACTCAACGCCGAAGAACG
CCGCATCCTCCTGCAACACGGCACAGAAGCACCGTTCTGCAACAGACTGCTGGACAACAACCAGCTTGGAACCTACACCT
GCCGGCTCTGCGGCCTCCCCCTCTTCCACTCCAACGCCAAATTCAAATCTGGCACTGGCTGGCCGAGCTTCTTCGAACCC
TACACACACACACATATACGCAAACAACACGACACCAGCCACGGCATGATCCGCACCGAAATCCTCTGCGCACGCTGCAA
CAGCCACCTTGGCCACCTCTTCCCGGACGGCCCGCCACCGACCTACGAACGGTATTGCCTGAACTCCGTCTCACTCACCT
TTATCCCAACCGGCACACTGCTTCCAGATCAACTACACCGCGGCGATAACACCACATACCGCACCTGA

Upstream 100 bases:

>100_bases
CACAGTACATCGCCAAATCTATCCACAAAAACGTGACTTCATCCAAAACATCAACAACCGTATTGACATCTTCCACCGCA
TCCTCTCCTCAGACCTTACG

Downstream 100 bases:

>100_bases
CACACCCTGCAATCTCAAAACACACACAACACACCGCTAAAACACATTTTCACCTCAATAAAAAGGCCCCTACACCATCC
CAATAAACAGCCGCCCCCTG

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MNVTFDLTPPSPSQREALIATLNAEERRILLQHGTEAPFCNRLLDNNQLGTYTCRLCGLPLFHSNAKFKSGTGWPSFFEP
YTHTHIRKQHDTSHGMIRTEILCARCNSHLGHLFPDGPPPTYERYCLNSVSLTFIPTGTLLPDQLHRGDNTTYRT

Sequences:

>Translated_155_residues
MNVTFDLTPPSPSQREALIATLNAEERRILLQHGTEAPFCNRLLDNNQLGTYTCRLCGLPLFHSNAKFKSGTGWPSFFEP
YTHTHIRKQHDTSHGMIRTEILCARCNSHLGHLFPDGPPPTYERYCLNSVSLTFIPTGTLLPDQLHRGDNTTYRT
>Mature_155_residues
MNVTFDLTPPSPSQREALIATLNAEERRILLQHGTEAPFCNRLLDNNQLGTYTCRLCGLPLFHSNAKFKSGTGWPSFFEP
YTHTHIRKQHDTSHGMIRTEILCARCNSHLGHLFPDGPPPTYERYCLNSVSLTFIPTGTLLPDQLHRGDNTTYRT

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family

Homologues:

Organism=Homo sapiens, GI117606353, Length=132, Percent_Identity=43.9393939393939, Blast_Score=118, Evalue=2e-27,
Organism=Homo sapiens, GI37620216, Length=125, Percent_Identity=43.2, Blast_Score=109, Evalue=1e-24,
Organism=Homo sapiens, GI301336164, Length=125, Percent_Identity=43.2, Blast_Score=108, Evalue=1e-24,
Organism=Homo sapiens, GI301336162, Length=125, Percent_Identity=43.2, Blast_Score=108, Evalue=1e-24,
Organism=Homo sapiens, GI73089054, Length=125, Percent_Identity=43.2, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1788077, Length=119, Percent_Identity=53.781512605042, Blast_Score=137, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17553450, Length=127, Percent_Identity=42.5196850393701, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI115532676, Length=127, Percent_Identity=42.5196850393701, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6319816, Length=112, Percent_Identity=39.2857142857143, Blast_Score=78, Evalue=7e-16,
Organism=Drosophila melanogaster, GI221378664, Length=126, Percent_Identity=38.0952380952381, Blast_Score=106, Evalue=7e-24,
Organism=Drosophila melanogaster, GI221378662, Length=133, Percent_Identity=36.0902255639098, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24645799, Length=122, Percent_Identity=40.1639344262295, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI45553335, Length=122, Percent_Identity=40.1639344262295, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21356369, Length=122, Percent_Identity=40.1639344262295, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24645801, Length=133, Percent_Identity=36.8421052631579, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24645804, Length=133, Percent_Identity=36.8421052631579, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MSRB_XYLF2 (B2I8Y4)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001830599.1
- ProteinModelPortal:   B2I8Y4
- SMR:   B2I8Y4
- GeneID:   6203243
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_1925
- HOGENOM:   HBG715255
- OMA:   RPWTGEL
- ProtClustDB:   PRK00222
- HAMAP:   MF_01400
- InterPro:   IPR002579
- InterPro:   IPR011057
- Gene3D:   G3DSA:2.170.150.20
- TIGRFAMs:   TIGR00357

Pfam domain/function: PF01641 SelR; SSF51316 Mss4_like

EC number: =1.8.4.12

Molecular weight: Translated: 17568; Mature: 17568

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: NA

Important sites: ACT_SITE 126-126

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVTFDLTPPSPSQREALIATLNAEERRILLQHGTEAPFCNRLLDNNQLGTYTCRLCGLP
CCEEEECCCCCCCCCCEEEEEECCCHHEEEEECCCCCHHHHHHHCCCCCCEEEEEECCCC
LFHSNAKFKSGTGWPSFFEPYTHTHIRKQHDTSHGMIRTEILCARCNSHLGHLFPDGPPP
EECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
TYERYCLNSVSLTFIPTGTLLPDQLHRGDNTTYRT
CHHHHHCCCCEEEEEECCCCCHHHHHCCCCCCCCC
>Mature Secondary Structure
MNVTFDLTPPSPSQREALIATLNAEERRILLQHGTEAPFCNRLLDNNQLGTYTCRLCGLP
CCEEEECCCCCCCCCCEEEEEECCCHHEEEEECCCCCHHHHHHHCCCCCCEEEEEECCCC
LFHSNAKFKSGTGWPSFFEPYTHTHIRKQHDTSHGMIRTEILCARCNSHLGHLFPDGPPP
EECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
TYERYCLNSVSLTFIPTGTLLPDQLHRGDNTTYRT
CHHHHHCCCCEEEEEECCCCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA