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The map label for this gene is yhdG [H]

Identifier: 182682278

GI number: 182682278

Start: 1947956

End: 1949398

Strand: Direct

Name: yhdG [H]

Synonym: XfasM23_1760

Alternate gene names: 182682278

Gene position: 1947956-1949398 (Clockwise)

Preceding gene: 182682277

Following gene: 182682280

Centisome position: 76.82

GC content: 54.4

Gene sequence:

>1443_bases
ATGTCATTCTTGCCATCGTTTCTAAAGCGCAAGTCCATTGATCTAATCACCGTGCATGAAGAAGGACGACGCCTGGTCCC
TACACTGAGCTGGCCACATCTGATCGCATTTGGGATTGGTGCAATCGTTGGCACTGGGATCTACACCTTAATCGGGGTCG
GGGCAGAAAAAGCGGGGCCAGCAGTCCTCCTCTCATTCGTCATCGCTGGGGTCATCTGTGCCTGCGCAGCGCTGGCATAT
GCCGAGATGGCGACAATGATGCCAGTGGCAGGCAGCACTTATACGTACAGCTATGTGGCCCTCGGTGAGGGGATTGCCTG
GATCGTGGGGTGGAGTCTCATCTTAGAGTACTCACTGGTGGTCAGCACTGTTGCGGTGGGATGGTCCGGGTACATGACTG
GGTTTCTCAAGAGCGTAGGGGTCGATATGCCGCTGGCGCTCACCGCCGGACCGTATGCTGGCGGGATAATCAATCTTCCA
GCGGCAGTGATCACCTGCGTTGTGGCTGGACTGCTGATCGTCGGCACAAAAGAAAGCACCACACTCAACGCGGTTCTGGT
GGTGGTTAAGATCATTGCGCTCTCTGTGTTCGTCGTGATCGCGCTACCACATTTTGATATGGCTCATCTGAAACCATTCA
TGCCCTATGGGTTTATCAAGTCAATCGACACCGGAGGTGTGGAACGCGGGGTGATGGCCGCTGCAGCAATCATTTTTTTT
GCTTTCTATGGTTTCGATGCAATCTCCACCGCAGCCGAGGAAACTAAGAATCCAAGCCGCGATCTGTCCATCGGCATCAT
CGGTTCTATGATCGGATGCACCTTAATTTACGTATTAGTGGCACTAGCTGCGATCGGTGCAATGCACTACACCGTGTTCG
GTCCCAGTACTGAACCGCTGGCGCTGATTCTGCGGCAACTTGACCAAGGCAACACCGCCAGGCTCATCGGAGCAGCTGCG
ATTATCGCGCTACCCACTGTACTGTTAGCCTTTTTATATGGACAAAGCCGCATTTTGTTCGTGATGTCTCGGGATGGGCT
GCTGCCACGTGGATTGTCGACGGTGAATGCACGCACAGGAACACCGATCGCCACGACACTGTTCACCGCAGTTCTCGTCG
CAACGGCAGCAGGGTTGGTGCCATTGGGCGAGATTGCCGCGCTGGCTAATGCTGGCACGCTGACTGCGTTCATCGCAGTA
GCTTTATGCCTGCTGGTACTGCGGGTACGTGAACCACAGCGCGTGCGTGCATTCCGTACACCACTGGCTTGGGTCGTCGG
GCCAATCGCAATTGCTGGTTGTTTGTATCTGTTCTGGAGTCTACCAAAGATGACACAATACCTTTTTCTGCTGTGGAACG
CACTGGGATTGTGTGTGTATCTGGTCTATGGGCGCCACACCAGCCTGCTATCAAAGGCGGTAAGCATCGACACGCCAAGA
TAA

Upstream 100 bases:

>100_bases
GAATCACATCTAATTGAAACAAATTTCAATTTTAGTGAGACTCTTTATTACGCCACATGTGTCATATCCGTGTGGTTTTC
TTCACTCATCGAGACTCGTA

Downstream 100 bases:

>100_bases
CCCAACAGTCAACAGATTAATGAGTACGCGACGTTATGGATGCAAACACGACGGGTGACACTCGCTGATGAGATACCGGT
GAGCATGGACGTACTGCCAG

Product: amino acid permease-associated protein

Products: Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MSFLPSFLKRKSIDLITVHEEGRRLVPTLSWPHLIAFGIGAIVGTGIYTLIGVGAEKAGPAVLLSFVIAGVICACAALAY
AEMATMMPVAGSTYTYSYVALGEGIAWIVGWSLILEYSLVVSTVAVGWSGYMTGFLKSVGVDMPLALTAGPYAGGIINLP
AAVITCVVAGLLIVGTKESTTLNAVLVVVKIIALSVFVVIALPHFDMAHLKPFMPYGFIKSIDTGGVERGVMAAAAIIFF
AFYGFDAISTAAEETKNPSRDLSIGIIGSMIGCTLIYVLVALAAIGAMHYTVFGPSTEPLALILRQLDQGNTARLIGAAA
IIALPTVLLAFLYGQSRILFVMSRDGLLPRGLSTVNARTGTPIATTLFTAVLVATAAGLVPLGEIAALANAGTLTAFIAV
ALCLLVLRVREPQRVRAFRTPLAWVVGPIAIAGCLYLFWSLPKMTQYLFLLWNALGLCVYLVYGRHTSLLSKAVSIDTPR

Sequences:

>Translated_480_residues
MSFLPSFLKRKSIDLITVHEEGRRLVPTLSWPHLIAFGIGAIVGTGIYTLIGVGAEKAGPAVLLSFVIAGVICACAALAY
AEMATMMPVAGSTYTYSYVALGEGIAWIVGWSLILEYSLVVSTVAVGWSGYMTGFLKSVGVDMPLALTAGPYAGGIINLP
AAVITCVVAGLLIVGTKESTTLNAVLVVVKIIALSVFVVIALPHFDMAHLKPFMPYGFIKSIDTGGVERGVMAAAAIIFF
AFYGFDAISTAAEETKNPSRDLSIGIIGSMIGCTLIYVLVALAAIGAMHYTVFGPSTEPLALILRQLDQGNTARLIGAAA
IIALPTVLLAFLYGQSRILFVMSRDGLLPRGLSTVNARTGTPIATTLFTAVLVATAAGLVPLGEIAALANAGTLTAFIAV
ALCLLVLRVREPQRVRAFRTPLAWVVGPIAIAGCLYLFWSLPKMTQYLFLLWNALGLCVYLVYGRHTSLLSKAVSIDTPR
>Mature_479_residues
SFLPSFLKRKSIDLITVHEEGRRLVPTLSWPHLIAFGIGAIVGTGIYTLIGVGAEKAGPAVLLSFVIAGVICACAALAYA
EMATMMPVAGSTYTYSYVALGEGIAWIVGWSLILEYSLVVSTVAVGWSGYMTGFLKSVGVDMPLALTAGPYAGGIINLPA
AVITCVVAGLLIVGTKESTTLNAVLVVVKIIALSVFVVIALPHFDMAHLKPFMPYGFIKSIDTGGVERGVMAAAAIIFFA
FYGFDAISTAAEETKNPSRDLSIGIIGSMIGCTLIYVLVALAAIGAMHYTVFGPSTEPLALILRQLDQGNTARLIGAAAI
IALPTVLLAFLYGQSRILFVMSRDGLLPRGLSTVNARTGTPIATTLFTAVLVATAAGLVPLGEIAALANAGTLTAFIAVA
LCLLVLRVREPQRVRAFRTPLAWVVGPIAIAGCLYLFWSLPKMTQYLFLLWNALGLCVYLVYGRHTSLLSKAVSIDTPR

Specific function: Permease That Is Involved In The Transport Across The Cytoplasmic Membrane Of Phenylalanine. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258614005, Length=444, Percent_Identity=32.2072072072072, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI258614003, Length=444, Percent_Identity=32.2072072072072, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI258645169, Length=444, Percent_Identity=33.3333333333333, Blast_Score=193, Evalue=4e-49,
Organism=Homo sapiens, GI4507047, Length=445, Percent_Identity=32.5842696629214, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI114326544, Length=429, Percent_Identity=31.2354312354312, Blast_Score=169, Evalue=7e-42,
Organism=Homo sapiens, GI114326550, Length=429, Percent_Identity=31.2354312354312, Blast_Score=169, Evalue=7e-42,
Organism=Homo sapiens, GI181337167, Length=407, Percent_Identity=32.1867321867322, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI110347453, Length=423, Percent_Identity=33.806146572104, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI115648063, Length=409, Percent_Identity=26.4058679706601, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI115648022, Length=409, Percent_Identity=26.4058679706601, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI186910308, Length=410, Percent_Identity=24.8780487804878, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI186910306, Length=410, Percent_Identity=24.8780487804878, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI186910304, Length=410, Percent_Identity=24.8780487804878, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI71979932, Length=435, Percent_Identity=25.9770114942529, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1786302, Length=371, Percent_Identity=24.2587601078167, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786789, Length=409, Percent_Identity=24.2053789731051, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789017, Length=358, Percent_Identity=23.463687150838, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081869, Length=459, Percent_Identity=23.0936819172113, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081915, Length=432, Percent_Identity=23.6111111111111, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786602, Length=415, Percent_Identity=23.855421686747, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=409, Percent_Identity=33.2518337408313, Blast_Score=185, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI17533459, Length=388, Percent_Identity=29.8969072164948, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17531343, Length=387, Percent_Identity=28.4237726098191, Blast_Score=131, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17540018, Length=446, Percent_Identity=23.9910313901345, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32566699, Length=377, Percent_Identity=24.6684350132626, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17568033, Length=435, Percent_Identity=23.9080459770115, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24668806, Length=421, Percent_Identity=33.2541567695962, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI21356285, Length=421, Percent_Identity=33.2541567695962, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI24668802, Length=421, Percent_Identity=33.2541567695962, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI24667468, Length=393, Percent_Identity=33.587786259542, Blast_Score=192, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24666159, Length=415, Percent_Identity=33.0120481927711, Blast_Score=182, Evalue=6e-46,
Organism=Drosophila melanogaster, GI221512776, Length=415, Percent_Identity=33.0120481927711, Blast_Score=181, Evalue=7e-46,
Organism=Drosophila melanogaster, GI161077963, Length=438, Percent_Identity=29.6803652968037, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI281366235, Length=427, Percent_Identity=27.4004683840749, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI116007820, Length=427, Percent_Identity=27.4004683840749, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI116007818, Length=399, Percent_Identity=27.5689223057644, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI85725152, Length=399, Percent_Identity=27.5689223057644, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI221331183, Length=422, Percent_Identity=26.0663507109005, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17647653, Length=422, Percent_Identity=26.0663507109005, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24664379, Length=422, Percent_Identity=26.0663507109005, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357367, Length=355, Percent_Identity=26.4788732394366, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI45550968, Length=365, Percent_Identity=24.3835616438356, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19921172, Length=365, Percent_Identity=24.3835616438356, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50593; Mature: 50462

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLPSFLKRKSIDLITVHEEGRRLVPTLSWPHLIAFGIGAIVGTGIYTLIGVGAEKAGP
CCCCHHHHHHCCCCEEEEECCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
AVLLSFVIAGVICACAALAYAEMATMMPVAGSTYTYSYVALGEGIAWIVGWSLILEYSLV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHH
VSTVAVGWSGYMTGFLKSVGVDMPLALTAGPYAGGIINLPAAVITCVVAGLLIVGTKEST
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHEECCCCCH
TLNAVLVVVKIIALSVFVVIALPHFDMAHLKPFMPYGFIKSIDTGGVERGVMAAAAIIFF
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHH
AFYGFDAISTAAEETKNPSRDLSIGIIGSMIGCTLIYVLVALAAIGAMHYTVFGPSTEPL
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHH
ALILRQLDQGNTARLIGAAAIIALPTVLLAFLYGQSRILFVMSRDGLLPRGLSTVNARTG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCC
TPIATTLFTAVLVATAAGLVPLGEIAALANAGTLTAFIAVALCLLVLRVREPQRVRAFRT
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHC
PLAWVVGPIAIAGCLYLFWSLPKMTQYLFLLWNALGLCVYLVYGRHTSLLSKAVSIDTPR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SFLPSFLKRKSIDLITVHEEGRRLVPTLSWPHLIAFGIGAIVGTGIYTLIGVGAEKAGP
CCCHHHHHHCCCCEEEEECCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
AVLLSFVIAGVICACAALAYAEMATMMPVAGSTYTYSYVALGEGIAWIVGWSLILEYSLV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHH
VSTVAVGWSGYMTGFLKSVGVDMPLALTAGPYAGGIINLPAAVITCVVAGLLIVGTKEST
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHEECCCCCH
TLNAVLVVVKIIALSVFVVIALPHFDMAHLKPFMPYGFIKSIDTGGVERGVMAAAAIIFF
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHH
AFYGFDAISTAAEETKNPSRDLSIGIIGSMIGCTLIYVLVALAAIGAMHYTVFGPSTEPL
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHH
ALILRQLDQGNTARLIGAAAIIALPTVLLAFLYGQSRILFVMSRDGLLPRGLSTVNARTG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCC
TPIATTLFTAVLVATAAGLVPLGEIAALANAGTLTAFIAVALCLLVLRVREPQRVRAFRT
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHC
PLAWVVGPIAIAGCLYLFWSLPKMTQYLFLLWNALGLCVYLVYGRHTSLLSKAVSIDTPR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-phenylalanine [Periplasm] = Proton [Cytoplasm] + L-phenylalanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]