Click here to switch to the map view.

The map label for this gene is phoA [H]

Identifier: 182682124

GI number: 182682124

Start: 1776513

End: 1778210

Strand: Reverse

Name: phoA [H]

Synonym: XfasM23_1602

Alternate gene names: 182682124

Gene position: 1778210-1776513 (Counterclockwise)

Preceding gene: 182682127

Following gene: 182682123

Centisome position: 70.13

GC content: 57.42

Gene sequence:

>1698_bases
ATGTTCCGACGTTTTTCTACTTTCCTCATTCTTCCTGTCGTGTCATTTGCCATAGCGGTTTCTTTCCCATCTGCTGCCAC
TTCTACTACCCAGCTGAGCGTGCCCAAAGTGACTCCTCCTGCCGCTGAGACCCCGCAATGGTGGTATCAGAGCGGCGCTA
CACGTGCTGCGGCTAACGGTGCCATGGCTGGCAAAGCCAAAAACGTCATCCTATTTCTCGGCGACGGCATGAGCTTCACC
ACCGTAGCCGCTGCACGCATCCTGGAAGGCCAGCGCAACGCTGCCACTGGCGAAGAGAACGTATTGTCCTGGGAGCATTT
TCCTGCCACCGCATTCAGCAAAACCTACAACACCGATGCCCAGACCGCAGACTCAGCCGGTTCCATGACCGCGATCACCT
CTGGAGTAAAGACCCACAGGGGCGCGATCGGCGTCAGTGCAGGTCAGCGCAACGACTGCGTTGATAGCCTCGGCAAAAGT
CTACTTACCTGGCTGACACTGGCAGACAGTGCCGGTATGGCGACCGGCATCATAACGACCACCCGTATCACTCACGCCAC
CCCGGCGGCGCTCTACGCACATACCCCGGAACGTCATTGGGAAAGTGATGCCAACCTGCCTGAAGCCGCCAAAGCGGGCG
GCTGCCGCGATATTGCCCAACAACTCCTCACCTCTACCCGCTATGGGCGTGGTCCTCTGGTGGTGCTGGGTGGTGGTCGC
GCCCAATTCATGCCTGCGCACCAACATGACCCCGAATATGCTGAGCGTACTGGCTTACGTTTGGATGGACGCGACCTCAT
TGAAGAATGGAAACGTGCACATCCCAATGGTGCTTATGTGTGGAACACCCACCAATTCAACGCTGATGCTGGCGCACCGG
CCCTGCTGGGTTTATTTGAGCCCAGCCATATGCAGTTTGAACACGATCGCGACCGACACCCCAACGGCGAGCCTAGCTTG
GCCGAGATGACACGTACCGCGATCCAATCGCTGTCTCGTGATCCACATGGTTTTGTACTGATGGTTGAAGGAGGCCGGAT
TGATCACGCCCATCATGCCGGTAACGCCTACAGAGCCTTGGATGAAACCATCGCACTCTCAGATGCAGTACGCGCCGCCG
TACAGACAGCCCCTAAAGATACCTTGATTATTGTCACTGCCGACCATGCCCATACCCTTAACTTTGTTGGCTACCCAGTC
CGCGGCAACCCCATATTGGGCAAAGTGCGTAGCAGCAGCCGTGATGCAGGAGACCGCACCCAGTACGCACATGATTTAAA
TGCCTTGCCCTATACCACATTGACTTACGCAAACGGTCCTGGCCACACCGCCGCCAGCAATACACAGTCGGCTGGAACCA
AACACTTCAACCATCAACCCAGTACCTATGAATTAGTCCGTGGTCGCCCAGATCTGACCACGATCGACACCCAAGCGCCC
GACTATCTGCAAGAAGCACTGGTCCCACTGAAGAAGGAGAGCCACAGCGGCGAAGACGTCGGCATCTGGGCCACAGGCCC
CGGCAGTGCTGCGTTCCGCGGCGTCCTTGAACAACATGTCATCTACCATGTCATCGTCCAAGCGACACCCGCATTACGCC
AGCGCCTGTGTGCCGCTGGCACATGTAACGCCGCTGGCGTGCCGATCAAGTTGCCACAGCTGGCCGACTTCGAACGCAAA
GACCAGAGCAGGGAGTGA

Upstream 100 bases:

>100_bases
ATTCGTATATGAAACCACAGTTGAACACTGTCATCTATGTGACTTTATCGTCTGTTAATAATGAATGCGTTTCTCAATTT
GTCGACCATCAAATCACATT

Downstream 100 bases:

>100_bases
ACCACTCCCACCATGCCTCCCTGATGTACACCATGCGTATCCTGAGCAGCCTTGGACCCACAAAATGCCTGATTGCTCAC
TCCAAGAGTGTCCGTATCGC

Product: alkaline phosphatase

Products: NA

Alternate protein names: APase [H]

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MFRRFSTFLILPVVSFAIAVSFPSAATSTTQLSVPKVTPPAAETPQWWYQSGATRAAANGAMAGKAKNVILFLGDGMSFT
TVAAARILEGQRNAATGEENVLSWEHFPATAFSKTYNTDAQTADSAGSMTAITSGVKTHRGAIGVSAGQRNDCVDSLGKS
LLTWLTLADSAGMATGIITTTRITHATPAALYAHTPERHWESDANLPEAAKAGGCRDIAQQLLTSTRYGRGPLVVLGGGR
AQFMPAHQHDPEYAERTGLRLDGRDLIEEWKRAHPNGAYVWNTHQFNADAGAPALLGLFEPSHMQFEHDRDRHPNGEPSL
AEMTRTAIQSLSRDPHGFVLMVEGGRIDHAHHAGNAYRALDETIALSDAVRAAVQTAPKDTLIIVTADHAHTLNFVGYPV
RGNPILGKVRSSSRDAGDRTQYAHDLNALPYTTLTYANGPGHTAASNTQSAGTKHFNHQPSTYELVRGRPDLTTIDTQAP
DYLQEALVPLKKESHSGEDVGIWATGPGSAAFRGVLEQHVIYHVIVQATPALRQRLCAAGTCNAAGVPIKLPQLADFERK
DQSRE

Sequences:

>Translated_565_residues
MFRRFSTFLILPVVSFAIAVSFPSAATSTTQLSVPKVTPPAAETPQWWYQSGATRAAANGAMAGKAKNVILFLGDGMSFT
TVAAARILEGQRNAATGEENVLSWEHFPATAFSKTYNTDAQTADSAGSMTAITSGVKTHRGAIGVSAGQRNDCVDSLGKS
LLTWLTLADSAGMATGIITTTRITHATPAALYAHTPERHWESDANLPEAAKAGGCRDIAQQLLTSTRYGRGPLVVLGGGR
AQFMPAHQHDPEYAERTGLRLDGRDLIEEWKRAHPNGAYVWNTHQFNADAGAPALLGLFEPSHMQFEHDRDRHPNGEPSL
AEMTRTAIQSLSRDPHGFVLMVEGGRIDHAHHAGNAYRALDETIALSDAVRAAVQTAPKDTLIIVTADHAHTLNFVGYPV
RGNPILGKVRSSSRDAGDRTQYAHDLNALPYTTLTYANGPGHTAASNTQSAGTKHFNHQPSTYELVRGRPDLTTIDTQAP
DYLQEALVPLKKESHSGEDVGIWATGPGSAAFRGVLEQHVIYHVIVQATPALRQRLCAAGTCNAAGVPIKLPQLADFERK
DQSRE
>Mature_565_residues
MFRRFSTFLILPVVSFAIAVSFPSAATSTTQLSVPKVTPPAAETPQWWYQSGATRAAANGAMAGKAKNVILFLGDGMSFT
TVAAARILEGQRNAATGEENVLSWEHFPATAFSKTYNTDAQTADSAGSMTAITSGVKTHRGAIGVSAGQRNDCVDSLGKS
LLTWLTLADSAGMATGIITTTRITHATPAALYAHTPERHWESDANLPEAAKAGGCRDIAQQLLTSTRYGRGPLVVLGGGR
AQFMPAHQHDPEYAERTGLRLDGRDLIEEWKRAHPNGAYVWNTHQFNADAGAPALLGLFEPSHMQFEHDRDRHPNGEPSL
AEMTRTAIQSLSRDPHGFVLMVEGGRIDHAHHAGNAYRALDETIALSDAVRAAVQTAPKDTLIIVTADHAHTLNFVGYPV
RGNPILGKVRSSSRDAGDRTQYAHDLNALPYTTLTYANGPGHTAASNTQSAGTKHFNHQPSTYELVRGRPDLTTIDTQAP
DYLQEALVPLKKESHSGEDVGIWATGPGSAAFRGVLEQHVIYHVIVQATPALRQRLCAAGTCNAAGVPIKLPQLADFERK
DQSRE

Specific function: Unknown

COG id: COG1785

COG function: function code P; Alkaline phosphatase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkaline phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI157266292, Length=505, Percent_Identity=41.980198019802, Blast_Score=373, Evalue=1e-103,
Organism=Homo sapiens, GI157266296, Length=524, Percent_Identity=40.6488549618321, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI94721246, Length=524, Percent_Identity=40.6488549618321, Blast_Score=364, Evalue=1e-100,
Organism=Homo sapiens, GI116734717, Length=535, Percent_Identity=39.0654205607477, Blast_Score=343, Evalue=3e-94,
Organism=Homo sapiens, GI294660770, Length=469, Percent_Identity=41.36460554371, Blast_Score=333, Evalue=4e-91,
Organism=Homo sapiens, GI294660772, Length=437, Percent_Identity=39.1304347826087, Blast_Score=291, Evalue=1e-78,
Organism=Escherichia coli, GI48994877, Length=359, Percent_Identity=32.8690807799443, Blast_Score=127, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320689, Length=355, Percent_Identity=33.5211267605634, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI21358067, Length=469, Percent_Identity=42.4307036247335, Blast_Score=319, Evalue=3e-87,
Organism=Drosophila melanogaster, GI85725200, Length=487, Percent_Identity=40.041067761807, Blast_Score=310, Evalue=2e-84,
Organism=Drosophila melanogaster, GI85815833, Length=487, Percent_Identity=40.041067761807, Blast_Score=310, Evalue=2e-84,
Organism=Drosophila melanogaster, GI24657835, Length=514, Percent_Identity=38.9105058365759, Blast_Score=303, Evalue=3e-82,
Organism=Drosophila melanogaster, GI21355149, Length=468, Percent_Identity=40.1709401709402, Blast_Score=301, Evalue=1e-81,
Organism=Drosophila melanogaster, GI24657842, Length=513, Percent_Identity=38.5964912280702, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI21355151, Length=481, Percent_Identity=41.3721413721414, Blast_Score=296, Evalue=3e-80,
Organism=Drosophila melanogaster, GI21355981, Length=562, Percent_Identity=36.8327402135231, Blast_Score=288, Evalue=6e-78,
Organism=Drosophila melanogaster, GI24651554, Length=534, Percent_Identity=38.2022471910112, Blast_Score=283, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24585213, Length=572, Percent_Identity=36.1888111888112, Blast_Score=283, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24657827, Length=505, Percent_Identity=38.8118811881188, Blast_Score=279, Evalue=3e-75,
Organism=Drosophila melanogaster, GI19921912, Length=572, Percent_Identity=36.8881118881119, Blast_Score=277, Evalue=1e-74,
Organism=Drosophila melanogaster, GI18859923, Length=538, Percent_Identity=35.6877323420074, Blast_Score=277, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24651556, Length=478, Percent_Identity=39.1213389121339, Blast_Score=261, Evalue=8e-70,
Organism=Drosophila melanogaster, GI24645593, Length=319, Percent_Identity=27.5862068965517, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR001952
- InterPro:   IPR018299
- InterPro:   IPR017850 [H]

Pfam domain/function: PF00245 Alk_phosphatase [H]

EC number: =3.1.3.1 [H]

Molecular weight: Translated: 60738; Mature: 60738

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRRFSTFLILPVVSFAIAVSFPSAATSTTQLSVPKVTPPAAETPQWWYQSGATRAAANG
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCHHHHHCCCCHHHCCC
AMAGKAKNVILFLGDGMSFTTVAAARILEGQRNAATGEENVLSWEHFPATAFSKTYNTDA
CCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCHHHHHCCCCCC
QTADSAGSMTAITSGVKTHRGAIGVSAGQRNDCVDSLGKSLLTWLTLADSAGMATGIITT
CCCCCCCCHHHHHHCHHHHCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
TRITHATPAALYAHTPERHWESDANLPEAAKAGGCRDIAQQLLTSTRYGRGPLVVLGGGR
EEECCCCCHHEEECCCHHHCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCEEEEECCC
AQFMPAHQHDPEYAERTGLRLDGRDLIEEWKRAHPNGAYVWNTHQFNADAGAPALLGLFE
EEECCCCCCCCCHHHHCCCCCCCHHHHHHHHHCCCCCCEEEECEEECCCCCCCCEEEECC
PSHMQFEHDRDRHPNGEPSLAEMTRTAIQSLSRDPHGFVLMVEGGRIDHAHHAGNAYRAL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHCCCHHHHH
DETIALSDAVRAAVQTAPKDTLIIVTADHAHTLNFVGYPVRGNPILGKVRSSSRDAGDRT
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEECCCCCCEEEECCCCCCCCCCHH
QYAHDLNALPYTTLTYANGPGHTAASNTQSAGTKHFNHQPSTYELVRGRPDLTTIDTQAP
HHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEECCCCH
DYLQEALVPLKKESHSGEDVGIWATGPGSAAFRGVLEQHVIYHVIVQATPALRQRLCAAG
HHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC
TCNAAGVPIKLPQLADFERKDQSRE
CCCCCCCCEECCCCCCCHHHCCCCC
>Mature Secondary Structure
MFRRFSTFLILPVVSFAIAVSFPSAATSTTQLSVPKVTPPAAETPQWWYQSGATRAAANG
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCHHHHHCCCCHHHCCC
AMAGKAKNVILFLGDGMSFTTVAAARILEGQRNAATGEENVLSWEHFPATAFSKTYNTDA
CCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCHHHHHCCCCCC
QTADSAGSMTAITSGVKTHRGAIGVSAGQRNDCVDSLGKSLLTWLTLADSAGMATGIITT
CCCCCCCCHHHHHHCHHHHCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
TRITHATPAALYAHTPERHWESDANLPEAAKAGGCRDIAQQLLTSTRYGRGPLVVLGGGR
EEECCCCCHHEEECCCHHHCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCEEEEECCC
AQFMPAHQHDPEYAERTGLRLDGRDLIEEWKRAHPNGAYVWNTHQFNADAGAPALLGLFE
EEECCCCCCCCCHHHHCCCCCCCHHHHHHHHHCCCCCCEEEECEEECCCCCCCCEEEECC
PSHMQFEHDRDRHPNGEPSLAEMTRTAIQSLSRDPHGFVLMVEGGRIDHAHHAGNAYRAL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHCCCHHHHH
DETIALSDAVRAAVQTAPKDTLIIVTADHAHTLNFVGYPVRGNPILGKVRSSSRDAGDRT
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEECCCCCCEEEECCCCCCCCCCHH
QYAHDLNALPYTTLTYANGPGHTAASNTQSAGTKHFNHQPSTYELVRGRPDLTTIDTQAP
HHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEECCCCH
DYLQEALVPLKKESHSGEDVGIWATGPGSAAFRGVLEQHVIYHVIVQATPALRQRLCAAG
HHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC
TCNAAGVPIKLPQLADFERKDQSRE
CCCCCCCCEECCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2129542 [H]