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The map label for this gene is dsbE [H]

Identifier: 182682088

GI number: 182682088

Start: 1739104

End: 1739697

Strand: Direct

Name: dsbE [H]

Synonym: XfasM23_1566

Alternate gene names: 182682088

Gene position: 1739104-1739697 (Clockwise)

Preceding gene: 182682087

Following gene: 182682089

Centisome position: 68.59

GC content: 56.9

Gene sequence:

>594_bases
ATGTCTGATTCACCCCGCCGCTTTCCCACCCCGCTACTCCTTACAGGTGTCATGGGAGTGCTGATCCTGATCGCACTGCT
CACCTTCACATTAATGCGCTCCTGGGATAACGCATCGGACCAATCGGCACTACTCGGGAAACCAGCGCCAAACTTCTCAC
TCCCACTGCTGCATGACCCGTCACTGCAAATCAGCAACACCGACTTAGCCGGTGCCCCCTACCTGTTGCATGTCTGGGGC
AGCTGGTGTGCCGCCTGCGCCACCGAACAGCCCGTACTGACGCACTTTGCACTCAGCAAGCGGGTACGCGTGATTGGCTA
CAACTGGAAAGACCGGCGGGAAGATGCCTTGCAATGGCTCGAACAACTCGGCAACCCGTATTTGGCCGTGGTGTCTGATC
CAGAAGGCAAAACCGCTATAGATTGGGGCGTGACCGCCGCACCAACAACATTCTTGATTGACGGACGTGGGATCGTACGC
TGGCATCACAAAGGCGCCCTGAATCAGCAGATGATCGAACACAAACTACTACCGATCCTTGCCGATATCGAACACTCACC
CACCGCCGCACCCGCATTGCATCAGGCACCATGA

Upstream 100 bases:

>100_bases
CCATTCGTCCGCTGGATCTGGCTGGGCGCAGCACTGATGGCCCTGGGCGGGCTGATCGCTGCTGCTGATCGCCGGTTCCG
CCACCACCCGGAGTCATCGC

Downstream 100 bases:

>100_bases
AACACGCACGTGCACTTCTGCTATGTGCGGCATTGCCCTTTGCCATCCAAGCACAGCTAAGGAGCGATCCAACACCACTC
CACTATCGCGATACCGCCGA

Product: periplasmic protein thiol--disulfide oxidoreductase DsbE

Products: NA

Alternate protein names: Cytochrome c biogenesis protein CcmG [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MSDSPRRFPTPLLLTGVMGVLILIALLTFTLMRSWDNASDQSALLGKPAPNFSLPLLHDPSLQISNTDLAGAPYLLHVWG
SWCAACATEQPVLTHFALSKRVRVIGYNWKDRREDALQWLEQLGNPYLAVVSDPEGKTAIDWGVTAAPTTFLIDGRGIVR
WHHKGALNQQMIEHKLLPILADIEHSPTAAPALHQAP

Sequences:

>Translated_197_residues
MSDSPRRFPTPLLLTGVMGVLILIALLTFTLMRSWDNASDQSALLGKPAPNFSLPLLHDPSLQISNTDLAGAPYLLHVWG
SWCAACATEQPVLTHFALSKRVRVIGYNWKDRREDALQWLEQLGNPYLAVVSDPEGKTAIDWGVTAAPTTFLIDGRGIVR
WHHKGALNQQMIEHKLLPILADIEHSPTAAPALHQAP
>Mature_196_residues
SDSPRRFPTPLLLTGVMGVLILIALLTFTLMRSWDNASDQSALLGKPAPNFSLPLLHDPSLQISNTDLAGAPYLLHVWGS
WCAACATEQPVLTHFALSKRVRVIGYNWKDRREDALQWLEQLGNPYLAVVSDPEGKTAIDWGVTAAPTTFLIDGRGIVRW
HHKGALNQQMIEHKLLPILADIEHSPTAAPALHQAP

Specific function: Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=173, Percent_Identity=39.8843930635838, Blast_Score=126, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 21694; Mature: 21563

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSPRRFPTPLLLTGVMGVLILIALLTFTLMRSWDNASDQSALLGKPAPNFSLPLLHDP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECC
SLQISNTDLAGAPYLLHVWGSWCAACATEQPVLTHFALSKRVRVIGYNWKDRREDALQWL
CCEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEEECCCCHHHHHHHHHH
EQLGNPYLAVVSDPEGKTAIDWGVTAAPTTFLIDGRGIVRWHHKGALNQQMIEHKLLPIL
HHHCCCEEEEEECCCCCEEEECCCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHHHH
ADIEHSPTAAPALHQAP
HCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDSPRRFPTPLLLTGVMGVLILIALLTFTLMRSWDNASDQSALLGKPAPNFSLPLLHDP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECC
SLQISNTDLAGAPYLLHVWGSWCAACATEQPVLTHFALSKRVRVIGYNWKDRREDALQWL
CCEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEEECCCCHHHHHHHHHH
EQLGNPYLAVVSDPEGKTAIDWGVTAAPTTFLIDGRGIVRWHHKGALNQQMIEHKLLPIL
HHHCCCEEEEEECCCCCEEEECCCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHHHH
ADIEHSPTAAPALHQAP
HCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]