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The map label for this gene is cycW [H]

Identifier: 182682083

GI number: 182682083

Start: 1734960

End: 1735655

Strand: Direct

Name: cycW [H]

Synonym: XfasM23_1561

Alternate gene names: 182682083

Gene position: 1734960-1735655 (Clockwise)

Preceding gene: 182682082

Following gene: 182682084

Centisome position: 68.42

GC content: 62.36

Gene sequence:

>696_bases
ATGAGCGCACCGCCCCCTCCCCTATCCCTCTGGCAGGCCTCATCTGCCATCATCACCCGAGACCTGCGCCTACTGTGGCG
CCGCCGCGCCGCCGCCATACACCCCATCTTAGTTGCACTGCTCATTACCCTCCTCTTCACCCTCGGCCTGGGCCCCAAAC
CACAACAACTGGCAGACGCCGCCCCAACCATCCTATGGATCACAGTGCTCCTCGCAAGCTTACTGACACTGGACACACTG
TTCCGCGCCGACGTTGAAGACGGCACCATGGAACAATGGCTCCTCTCACCCGTCCCCCTCGCCTGGCTCATCGCCGTGCG
GATCGCCTGCCACTGGACCGCCAGCGTCCTACCACTGATCATCATCACCCCATTACTGGGCGCATTCCTGCAACTACCAC
ATGAACAACTGCCCATCGTGATGGCATCCCTACTATTGGGCACCCCACTACTAAGCCTCCTCGGCGCTGTCATCGCCGCA
CTGACCGTCACCATGCCACGCGCTGGGATCCTCGTCGCGCTCCTTGCACTCCCCCTATACGTCCCCGTCCTGATATTCGG
CACCGGCAGCATCACCGCCGCCACCCAGGGCCATGACAGTACTGGCGCACTCCTTCTCCTCGGCGCCGGCTTAGCCCTTG
GCACAGTACTAGCGCCACTCACCGCTGCCGCAGCAATCCGCATTTCACTCAGCTAA

Upstream 100 bases:

>100_bases
CCACACACCTTCACACCCAAGGCGGCACACTGCTCACCACACCCGGCGCGCTCCCCACACTGCCAGTCCCCACCCGCCTG
CTTCACTTACAGAAAGCTCC

Downstream 100 bases:

>100_bases
AACACCCTTGTTTATCCAAGCACCCACCACCGCATGAACACCTTTGTCCATACACTGCATCGGCTCAGCTCACCGCAGAC
GTTCGACCAATTCGCCGCCC

Product: heme exporter protein CcmB

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycW [H]

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MSAPPPPLSLWQASSAIITRDLRLLWRRRAAAIHPILVALLITLLFTLGLGPKPQQLADAAPTILWITVLLASLLTLDTL
FRADVEDGTMEQWLLSPVPLAWLIAVRIACHWTASVLPLIIITPLLGAFLQLPHEQLPIVMASLLLGTPLLSLLGAVIAA
LTVTMPRAGILVALLALPLYVPVLIFGTGSITAATQGHDSTGALLLLGAGLALGTVLAPLTAAAAIRISLS

Sequences:

>Translated_231_residues
MSAPPPPLSLWQASSAIITRDLRLLWRRRAAAIHPILVALLITLLFTLGLGPKPQQLADAAPTILWITVLLASLLTLDTL
FRADVEDGTMEQWLLSPVPLAWLIAVRIACHWTASVLPLIIITPLLGAFLQLPHEQLPIVMASLLLGTPLLSLLGAVIAA
LTVTMPRAGILVALLALPLYVPVLIFGTGSITAATQGHDSTGALLLLGAGLALGTVLAPLTAAAAIRISLS
>Mature_230_residues
SAPPPPLSLWQASSAIITRDLRLLWRRRAAAIHPILVALLITLLFTLGLGPKPQQLADAAPTILWITVLLASLLTLDTLF
RADVEDGTMEQWLLSPVPLAWLIAVRIACHWTASVLPLIIITPLLGAFLQLPHEQLPIVMASLLLGTPLLSLLGAVIAAL
TVTMPRAGILVALLALPLYVPVLIFGTGSITAATQGHDSTGALLLLGAGLALGTVLAPLTAAAAIRISLS

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=215, Percent_Identity=41.8604651162791, Blast_Score=117, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 24236; Mature: 24104

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPPPPLSLWQASSAIITRDLRLLWRRRAAAIHPILVALLITLLFTLGLGPKPQQLADA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
APTILWITVLLASLLTLDTLFRADVEDGTMEQWLLSPVPLAWLIAVRIACHWTASVLPLI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
IITPLLGAFLQLPHEQLPIVMASLLLGTPLLSLLGAVIAALTVTMPRAGILVALLALPLY
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
VPVLIFGTGSITAATQGHDSTGALLLLGAGLALGTVLAPLTAAAAIRISLS
HHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECC
>Mature Secondary Structure 
SAPPPPLSLWQASSAIITRDLRLLWRRRAAAIHPILVALLITLLFTLGLGPKPQQLADA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
APTILWITVLLASLLTLDTLFRADVEDGTMEQWLLSPVPLAWLIAVRIACHWTASVLPLI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
IITPLLGAFLQLPHEQLPIVMASLLLGTPLLSLLGAVIAALTVTMPRAGILVALLALPLY
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
VPVLIFGTGSITAATQGHDSTGALLLLGAGLALGTVLAPLTAAAAIRISLS
HHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]