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The map label for this gene is yfbQ [H]

Identifier: 182682022

GI number: 182682022

Start: 1658137

End: 1659411

Strand: Reverse

Name: yfbQ [H]

Synonym: XfasM23_1498

Alternate gene names: 182682022

Gene position: 1659411-1658137 (Counterclockwise)

Preceding gene: 182682039

Following gene: 182682020

Centisome position: 65.44

GC content: 54.75

Gene sequence:

>1275_bases
ATGTCTAATAGCCCGCAAACGCCGCTTGTTACGCGCCAGCGCCTGTCCGAAGTCCGCTATGAGATCCGAGGGGAGTTGGC
GCGCCGTGCGCGTGAGCTTGAGGCGGAGGGACGCAAGCTTATCAAGCTCAACATCGGTAATCCAGGTGCGTTCGGTTTTC
GGGCGCCAGAGCATCTGCAACGTGCTATTGCCGATGATATGGGACGTACCGATCCTTATACGCATCAGCAGGGTTTGCCA
ATCGCACGTGAGGCGATTGCTGCTGCTTATGCGCGACGTCACTATCCAGATGTTGATGCAGATCGGGTCTTTGTGGGGAA
TGGGGTTTCTGAGTTAATCGATTTGTCGTTGCGGGCGTTGCTTAATCCAGGCGATGAGGTGTTGGTTCCTTCACCGGATT
ATCCGCTGTGGTCGGCGGCGACGATTCTCAACGATGGTCGGCCGGTGTATTACCGTTGTGCGCCGGAGAACGGTTTCCAG
CCAGATGCAGTTGAGATCGAAACGCTGGTGTCTTCACGGACACGTGCGATTGTGTTGATTAATCCGAATAATCCCAGTGG
TGCCAATTATTCGCAGGAGTTATTGGAGCGGATTGTGGCAATCTCAGTGAAACATCATCTGCTGTTGTTGGTTGATGAGA
TTTACGATCAGATTTTGTATGACGGTGCGGTGTTTGTTCCAGTGGCTCCTTTGGCGGGGACGCATCCATGTATCACTTTC
AGTGGGCTGAGTAAGGTGCATCGTGCGTGCGGTTGGCGTGTGGGTTGGGCGTTGCTGTCCGGGAGTAGCATTCAAGTTGA
TAATCTGCGCAATGCGATGGATTTGCTGGGTGCGTTGCGTTTGTGTGCGAATGTCCCAGGGCAATATGCGATTGATGCGG
CGGTCAATGGGCCAGATACGATCACTCCGTTATGTTCGCCTGGTGGTCCTTTGTACGAGACGCGCCGTGCGGTGATTGAT
GCATGCGCGGCGAGTGAGCATTTGTCGTTGGTGGTGCCTGCTGGGGCATTATACGCGTTCCCATCGGTCGTGGGACCAGC
GGCGCGGCACTTTGATGATTATGCTTTTGCGCTGGAGTTGATGAATGAGGAGGGAGTGCTGGTGGTGCCTGGATCAAGTT
TTAATGTGCCATATCGGGATCACTTCCGCGTGACGTTGCTTCCTGATGCTGGGTTGATACGTGAAGTGTTTTCTCGTATT
GACCGGGCATTGTCGCGCCGTGCTGAGGTGGCTGAGAAGGTGGTGCCGCTCAAGTCGCGTAGCGCCGCCGCTTGA

Upstream 100 bases:

>100_bases
TCAGGCGCTGCTGAGTAAATGATAAAGGGATATAAGGTCTGACGTGGAGTTGTATTTTGAACTAACATGTCGACTTCCAG
TAAATTGATTTACATACGTG

Downstream 100 bases:

>100_bases
TATGAGTGCACGCGGCTCCCTCTGGGTGGGGTCTATGTGGTTTGCGAAGTAGGAGCGGTTGACGTACTCAATGTCAATCA
GGAAAGGCTGTGGAATTACG

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MSNSPQTPLVTRQRLSEVRYEIRGELARRARELEAEGRKLIKLNIGNPGAFGFRAPEHLQRAIADDMGRTDPYTHQQGLP
IAREAIAAAYARRHYPDVDADRVFVGNGVSELIDLSLRALLNPGDEVLVPSPDYPLWSAATILNDGRPVYYRCAPENGFQ
PDAVEIETLVSSRTRAIVLINPNNPSGANYSQELLERIVAISVKHHLLLLVDEIYDQILYDGAVFVPVAPLAGTHPCITF
SGLSKVHRACGWRVGWALLSGSSIQVDNLRNAMDLLGALRLCANVPGQYAIDAAVNGPDTITPLCSPGGPLYETRRAVID
ACAASEHLSLVVPAGALYAFPSVVGPAARHFDDYAFALELMNEEGVLVVPGSSFNVPYRDHFRVTLLPDAGLIREVFSRI
DRALSRRAEVAEKVVPLKSRSAAA

Sequences:

>Translated_424_residues
MSNSPQTPLVTRQRLSEVRYEIRGELARRARELEAEGRKLIKLNIGNPGAFGFRAPEHLQRAIADDMGRTDPYTHQQGLP
IAREAIAAAYARRHYPDVDADRVFVGNGVSELIDLSLRALLNPGDEVLVPSPDYPLWSAATILNDGRPVYYRCAPENGFQ
PDAVEIETLVSSRTRAIVLINPNNPSGANYSQELLERIVAISVKHHLLLLVDEIYDQILYDGAVFVPVAPLAGTHPCITF
SGLSKVHRACGWRVGWALLSGSSIQVDNLRNAMDLLGALRLCANVPGQYAIDAAVNGPDTITPLCSPGGPLYETRRAVID
ACAASEHLSLVVPAGALYAFPSVVGPAARHFDDYAFALELMNEEGVLVVPGSSFNVPYRDHFRVTLLPDAGLIREVFSRI
DRALSRRAEVAEKVVPLKSRSAAA
>Mature_423_residues
SNSPQTPLVTRQRLSEVRYEIRGELARRARELEAEGRKLIKLNIGNPGAFGFRAPEHLQRAIADDMGRTDPYTHQQGLPI
AREAIAAAYARRHYPDVDADRVFVGNGVSELIDLSLRALLNPGDEVLVPSPDYPLWSAATILNDGRPVYYRCAPENGFQP
DAVEIETLVSSRTRAIVLINPNNPSGANYSQELLERIVAISVKHHLLLLVDEIYDQILYDGAVFVPVAPLAGTHPCITFS
GLSKVHRACGWRVGWALLSGSSIQVDNLRNAMDLLGALRLCANVPGQYAIDAAVNGPDTITPLCSPGGPLYETRRAVIDA
CAASEHLSLVVPAGALYAFPSVVGPAARHFDDYAFALELMNEEGVLVVPGSSFNVPYRDHFRVTLLPDAGLIREVFSRID
RALSRRAEVAEKVVPLKSRSAAA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=399, Percent_Identity=28.3208020050125, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI4885351, Length=454, Percent_Identity=28.1938325991189, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI19263340, Length=472, Percent_Identity=26.0593220338983, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI215599424, Length=398, Percent_Identity=27.8894472361809, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI95147551, Length=216, Percent_Identity=31.0185185185185, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI169881279, Length=216, Percent_Identity=31.0185185185185, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI56713254, Length=377, Percent_Identity=24.1379310344828, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI56713256, Length=377, Percent_Identity=24.1379310344828, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI169881281, Length=143, Percent_Identity=32.8671328671329, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1788627, Length=399, Percent_Identity=43.3583959899749, Blast_Score=338, Evalue=3e-94,
Organism=Escherichia coli, GI1788722, Length=423, Percent_Identity=24.5862884160757, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786816, Length=419, Percent_Identity=25.7756563245823, Blast_Score=96, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17567663, Length=373, Percent_Identity=28.1501340482574, Blast_Score=138, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI71981209, Length=467, Percent_Identity=27.8372591006424, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71994476, Length=369, Percent_Identity=23.0352303523035, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71994472, Length=365, Percent_Identity=23.5616438356164, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17567369, Length=194, Percent_Identity=25.2577319587629, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71981215, Length=297, Percent_Identity=26.5993265993266, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6323118, Length=458, Percent_Identity=25.764192139738, Blast_Score=120, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6320317, Length=461, Percent_Identity=24.7288503253796, Blast_Score=119, Evalue=8e-28,
Organism=Saccharomyces cerevisiae, GI6322401, Length=379, Percent_Identity=25.3298153034301, Blast_Score=93, Evalue=7e-20,
Organism=Drosophila melanogaster, GI18859735, Length=391, Percent_Identity=29.156010230179, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24641770, Length=471, Percent_Identity=26.963906581741, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24641760, Length=471, Percent_Identity=26.963906581741, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24641768, Length=471, Percent_Identity=26.963906581741, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24641766, Length=471, Percent_Identity=26.963906581741, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24641764, Length=471, Percent_Identity=26.963906581741, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI45551451, Length=471, Percent_Identity=26.963906581741, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI28573069, Length=232, Percent_Identity=25.4310344827586, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24646114, Length=232, Percent_Identity=25.4310344827586, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI28573067, Length=232, Percent_Identity=25.4310344827586, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI28573065, Length=232, Percent_Identity=25.4310344827586, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 46211; Mature: 46080

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSPQTPLVTRQRLSEVRYEIRGELARRARELEAEGRKLIKLNIGNPGAFGFRAPEHLQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHH
RAIADDMGRTDPYTHQQGLPIAREAIAAAYARRHYPDVDADRVFVGNGVSELIDLSLRAL
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHH
LNPGDEVLVPSPDYPLWSAATILNDGRPVYYRCAPENGFQPDAVEIETLVSSRTRAIVLI
CCCCCCEEECCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEE
NPNNPSGANYSQELLERIVAISVKHHLLLLVDEIYDQILYDGAVFVPVAPLAGTHPCITF
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEH
SGLSKVHRACGWRVGWALLSGSSIQVDNLRNAMDLLGALRLCANVPGQYAIDAAVNGPDT
HHHHHHHHHHCCHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
ITPLCSPGGPLYETRRAVIDACAASEHLSLVVPAGALYAFPSVVGPAARHFDDYAFALEL
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCHHHHHHHHHHHHHHE
MNEEGVLVVPGSSFNVPYRDHFRVTLLPDAGLIREVFSRIDRALSRRAEVAEKVVPLKSR
ECCCCEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SAAA
CCCC
>Mature Secondary Structure 
SNSPQTPLVTRQRLSEVRYEIRGELARRARELEAEGRKLIKLNIGNPGAFGFRAPEHLQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHH
RAIADDMGRTDPYTHQQGLPIAREAIAAAYARRHYPDVDADRVFVGNGVSELIDLSLRAL
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHH
LNPGDEVLVPSPDYPLWSAATILNDGRPVYYRCAPENGFQPDAVEIETLVSSRTRAIVLI
CCCCCCEEECCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEE
NPNNPSGANYSQELLERIVAISVKHHLLLLVDEIYDQILYDGAVFVPVAPLAGTHPCITF
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEH
SGLSKVHRACGWRVGWALLSGSSIQVDNLRNAMDLLGALRLCANVPGQYAIDAAVNGPDT
HHHHHHHHHHCCHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
ITPLCSPGGPLYETRRAVIDACAASEHLSLVVPAGALYAFPSVVGPAARHFDDYAFALEL
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCHHHHHHHHHHHHHHE
MNEEGVLVVPGSSFNVPYRDHFRVTLLPDAGLIREVFSRIDRALSRRAEVAEKVVPLKSR
ECCCCEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SAAA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]