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The map label for this gene is hrcA

Identifier: 182681982

GI number: 182681982

Start: 1609621

End: 1610670

Strand: Reverse

Name: hrcA

Synonym: XfasM23_1457

Alternate gene names: 182681982

Gene position: 1610670-1609621 (Counterclockwise)

Preceding gene: 182681984

Following gene: 182681981

Centisome position: 63.52

GC content: 54.29

Gene sequence:

>1050_bases
ATGTGCGCTTCCTTTTCTCCTACGCTTGATTCCCGATCCCGACAATTGTTACGGACGTTGATTTCATGCTACATCCAGAA
CGGTGAGCCGATTGGTTCCAAGACGCTGGCCCAGCAGGCTGGACTCGACATCAGTCCGGCGACGATCCGTAACATCCTGG
CTGACTTGGAGGAACTTGGTCTACTCAATTCGCCGCATACATCGGCGGGGCGGGTGCCGACTGCACACGGGTACCGGATG
TTTGTGGACAGTTTGGTACAGATGCAGCCTCCCAGTGAAGATGATATTCGTCGGCTACGTGTTGAGATGACTGGTGGGGG
CACGCAGACGCTGTTGGGCAGTGCATCGGAAATTTTATCGGCGATGACTCATTTTGTAGGTGTGGTCAGCGCCCCACGGC
GTGAACAGTTCGTATTCCGCCATATTGATTTTGTGCCACTGGATGCGCGCCAGATCATGGCGATCCTAATTTTTGCTGAC
AATGAGGTGCAGAACCGGGTCATTGAGCCGCGTCGTGTGTACGAGCCTGGAGAGCTGGAACGGGTCAGCAATTATCTGAA
TGCACACTTCATCGGACGCACATTGGCCGATATCCGCACCACTGTGCTGTGCGAGCTACGCAAGGCCAAGGACGAGATGG
AACAGTTGTTGGCACATAGCCTGGATCTTGCTTCGCAGATGCTTGTGCCAAACGATAGTGAGGATATTGTGGTCACTGGC
CAGACCCGATTGATGGCGCTTCAGGATCTTTCTGACATGGATCGCTTGCGTGAGTTGTTTGAGATATTTGCGAGCAAGAG
GGAGATCCTGCAATTACTGGAGCGTACGATTGATGCACCTGGGGTGCGTATCTTCATTGGTGAGGAGACCGGAATGGTTT
CGATGGAGGATATTTCGTTGGTCACTGCGCCATATGCAGCGCACGGTCAGGTTTTGGGAGTGTTGGGAGTGATTGGGCCC
AAGCGGATGGCATATGACCGGGTCATCCCTCTGGTGCAGGTTGTAGCCCAGGTGCTGGGTACGGCACTGGAGCCGCCAAC
GATGCCTTAG

Upstream 100 bases:

>100_bases
AATCAAAAAACTTAGGGCGAGTTGAGAGGGTAGGGAGTGGGTAATCTTGCCAACGTTCCGCCGAAAAACTATTTGTTTCC
CTTCGTCTTACCAATACTCC

Downstream 100 bases:

>100_bases
GTCGGTTGAGCTGCATTGTCGCCATCGTTTGATGAATTATGCATGGATGGCTTGAAAGCTGGCGGCTTGCCCACATACGG
GTTGGGGTTGAGGCGGGCGT

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MCASFSPTLDSRSRQLLRTLISCYIQNGEPIGSKTLAQQAGLDISPATIRNILADLEELGLLNSPHTSAGRVPTAHGYRM
FVDSLVQMQPPSEDDIRRLRVEMTGGGTQTLLGSASEILSAMTHFVGVVSAPRREQFVFRHIDFVPLDARQIMAILIFAD
NEVQNRVIEPRRVYEPGELERVSNYLNAHFIGRTLADIRTTVLCELRKAKDEMEQLLAHSLDLASQMLVPNDSEDIVVTG
QTRLMALQDLSDMDRLRELFEIFASKREILQLLERTIDAPGVRIFIGEETGMVSMEDISLVTAPYAAHGQVLGVLGVIGP
KRMAYDRVIPLVQVVAQVLGTALEPPTMP

Sequences:

>Translated_349_residues
MCASFSPTLDSRSRQLLRTLISCYIQNGEPIGSKTLAQQAGLDISPATIRNILADLEELGLLNSPHTSAGRVPTAHGYRM
FVDSLVQMQPPSEDDIRRLRVEMTGGGTQTLLGSASEILSAMTHFVGVVSAPRREQFVFRHIDFVPLDARQIMAILIFAD
NEVQNRVIEPRRVYEPGELERVSNYLNAHFIGRTLADIRTTVLCELRKAKDEMEQLLAHSLDLASQMLVPNDSEDIVVTG
QTRLMALQDLSDMDRLRELFEIFASKREILQLLERTIDAPGVRIFIGEETGMVSMEDISLVTAPYAAHGQVLGVLGVIGP
KRMAYDRVIPLVQVVAQVLGTALEPPTMP
>Mature_349_residues
MCASFSPTLDSRSRQLLRTLISCYIQNGEPIGSKTLAQQAGLDISPATIRNILADLEELGLLNSPHTSAGRVPTAHGYRM
FVDSLVQMQPPSEDDIRRLRVEMTGGGTQTLLGSASEILSAMTHFVGVVSAPRREQFVFRHIDFVPLDARQIMAILIFAD
NEVQNRVIEPRRVYEPGELERVSNYLNAHFIGRTLADIRTTVLCELRKAKDEMEQLLAHSLDLASQMLVPNDSEDIVVTG
QTRLMALQDLSDMDRLRELFEIFASKREILQLLERTIDAPGVRIFIGEETGMVSMEDISLVTAPYAAHGQVLGVLGVIGP
KRMAYDRVIPLVQVVAQVLGTALEPPTMP

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HRCA_XYLF2 (B2I6F8)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001830142.1
- ProteinModelPortal:   B2I6F8
- GeneID:   6203350
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_1457
- HOGENOM:   HBG729878
- OMA:   LEQPHTS
- ProtClustDB:   PRK00082
- GO:   GO:0006350
- HAMAP:   MF_00081
- InterPro:   IPR005104
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF005485
- TIGRFAMs:   TIGR00331

Pfam domain/function: PF03444 DUF293; PF01628 HrcA

EC number: NA

Molecular weight: Translated: 38645; Mature: 38645

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCASFSPTLDSRSRQLLRTLISCYIQNGEPIGSKTLAQQAGLDISPATIRNILADLEELG
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHC
LLNSPHTSAGRVPTAHGYRMFVDSLVQMQPPSEDDIRRLRVEMTGGGTQTLLGSASEILS
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHEEEEEECCCCHHHHHCCHHHHHH
AMTHFVGVVSAPRREQFVFRHIDFVPLDARQIMAILIFADNEVQNRVIEPRRVYEPGELE
HHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHEEEEEECCCHHHHHCCCCHHCCCCCHHH
RVSNYLNAHFIGRTLADIRTTVLCELRKAKDEMEQLLAHSLDLASQMLVPNDSEDIVVTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEC
QTRLMALQDLSDMDRLRELFEIFASKREILQLLERTIDAPGVRIFIGEETGMVSMEDISL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEHHCCCE
VTAPYAAHGQVLGVLGVIGPKRMAYDRVIPLVQVVAQVLGTALEPPTMP
EECCCHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MCASFSPTLDSRSRQLLRTLISCYIQNGEPIGSKTLAQQAGLDISPATIRNILADLEELG
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHC
LLNSPHTSAGRVPTAHGYRMFVDSLVQMQPPSEDDIRRLRVEMTGGGTQTLLGSASEILS
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHEEEEEECCCCHHHHHCCHHHHHH
AMTHFVGVVSAPRREQFVFRHIDFVPLDARQIMAILIFADNEVQNRVIEPRRVYEPGELE
HHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHEEEEEECCCHHHHHCCCCHHCCCCCHHH
RVSNYLNAHFIGRTLADIRTTVLCELRKAKDEMEQLLAHSLDLASQMLVPNDSEDIVVTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEC
QTRLMALQDLSDMDRLRELFEIFASKREILQLLERTIDAPGVRIFIGEETGMVSMEDISL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEHHCCCE
VTAPYAAHGQVLGVLGVIGPKRMAYDRVIPLVQVVAQVLGTALEPPTMP
EECCCHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA