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The map label for this gene is pgsA [H]

Identifier: 182681940

GI number: 182681940

Start: 1569486

End: 1570115

Strand: Direct

Name: pgsA [H]

Synonym: XfasM23_1411

Alternate gene names: 182681940

Gene position: 1569486-1570115 (Clockwise)

Preceding gene: 182681939

Following gene: 182681943

Centisome position: 61.9

GC content: 48.57

Gene sequence:

>630_bases
ATGAAATTGACCGTCCCCACTTGGTTAACGCTGCTACGGATCGTGATGATCCCTGTGCTCATTGTGGTGTTCTATCTACC
TTATCAATGGAGCAATATTGTCGCTACGGGAGTGTTTGCGATCGCTGCAATTACCGACTGGCTTGATGGATGGATCGCAC
GTCGTTACGCGCAACATTCGTTATTGGGTGCGTTTTTAGACCCAGTTGCGGACAAATTGATGGTGGCCATCGCATTATTT
CTCATTGTGCAAGGTCACCCGACACCGTCGATGGCATTTTGGGCAGCAGTGATCGTTAGTCGTGAAATTGCAGTGTCAGC
ATTGCGTGAGTGGATGGCCGAAATTGGTCATCGTGCCAAGGTGCGTGTAGCTGTCCTTGGCAAAGTGAAGACGACGGCTC
AAATGATTGCGGTACTGTGTCTGCTCTATTCGGTGACACCCGAGAAGAAGGCGATCCATCAAATATGGTTTGGCCACTTG
ATCTTCCAAGTCGGTTATTGGACATTGCTGATTTCCGCGTTACTGACACTGTGGTCTGGTTTCCAGTATTTGCACGCTGC
CTGGCCTAGTTTACGTACCGGAAAACCTGTAGTGATTAAAACGCACATCAGCAAGAACCGACAAAATTAA

Upstream 100 bases:

>100_bases
TTGCCAGGGTGGAAGGCATCAGTACTGCGCTGGCAGCCAAGATTTACGCCAGCCTGCATGGACTATCGAAAAATGATGCA
GCAAATGCGTCGAGGGTGTC

Downstream 100 bases:

>100_bases
TAGTTGACAGCATTCGTCAAGCGTGTAGGATTTCGTGGCCCAAGCGGGAATAGCTCAGTTGGTAGAGCGCAACCTTGCCA
AGGTTGAGGTCGCGAGTTCG

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MKLTVPTWLTLLRIVMIPVLIVVFYLPYQWSNIVATGVFAIAAITDWLDGWIARRYAQHSLLGAFLDPVADKLMVAIALF
LIVQGHPTPSMAFWAAVIVSREIAVSALREWMAEIGHRAKVRVAVLGKVKTTAQMIAVLCLLYSVTPEKKAIHQIWFGHL
IFQVGYWTLLISALLTLWSGFQYLHAAWPSLRTGKPVVIKTHISKNRQN

Sequences:

>Translated_209_residues
MKLTVPTWLTLLRIVMIPVLIVVFYLPYQWSNIVATGVFAIAAITDWLDGWIARRYAQHSLLGAFLDPVADKLMVAIALF
LIVQGHPTPSMAFWAAVIVSREIAVSALREWMAEIGHRAKVRVAVLGKVKTTAQMIAVLCLLYSVTPEKKAIHQIWFGHL
IFQVGYWTLLISALLTLWSGFQYLHAAWPSLRTGKPVVIKTHISKNRQN
>Mature_209_residues
MKLTVPTWLTLLRIVMIPVLIVVFYLPYQWSNIVATGVFAIAAITDWLDGWIARRYAQHSLLGAFLDPVADKLMVAIALF
LIVQGHPTPSMAFWAAVIVSREIAVSALREWMAEIGHRAKVRVAVLGKVKTTAQMIAVLCLLYSVTPEKKAIHQIWFGHL
IFQVGYWTLLISALLTLWSGFQYLHAAWPSLRTGKPVVIKTHISKNRQN

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Homo sapiens, GI188536108, Length=153, Percent_Identity=32.6797385620915, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI10092647, Length=151, Percent_Identity=32.4503311258278, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1788220, Length=187, Percent_Identity=47.0588235294118, Blast_Score=164, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6320059, Length=217, Percent_Identity=32.258064516129, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 23527; Mature: 23527

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTVPTWLTLLRIVMIPVLIVVFYLPYQWSNIVATGVFAIAAITDWLDGWIARRYAQHS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGAFLDPVADKLMVAIALFLIVQGHPTPSMAFWAAVIVSREIAVSALREWMAEIGHRAK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VRVAVLGKVKTTAQMIAVLCLLYSVTPEKKAIHQIWFGHLIFQVGYWTLLISALLTLWSG
EHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FQYLHAAWPSLRTGKPVVIKTHISKNRQN
HHHHHHHCCCCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MKLTVPTWLTLLRIVMIPVLIVVFYLPYQWSNIVATGVFAIAAITDWLDGWIARRYAQHS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGAFLDPVADKLMVAIALFLIVQGHPTPSMAFWAAVIVSREIAVSALREWMAEIGHRAK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VRVAVLGKVKTTAQMIAVLCLLYSVTPEKKAIHQIWFGHLIFQVGYWTLLISALLTLWSG
EHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FQYLHAAWPSLRTGKPVVIKTHISKNRQN
HHHHHHHCCCCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA