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The map label for this gene is mtnC

Identifier: 182681877

GI number: 182681877

Start: 1483965

End: 1484663

Strand: Direct

Name: mtnC

Synonym: XfasM23_1345

Alternate gene names: 182681877

Gene position: 1483965-1484663 (Clockwise)

Preceding gene: 182681876

Following gene: 182681900

Centisome position: 58.52

GC content: 54.08

Gene sequence:

>699_bases
ATGAGCATGCCTCAAGCAATTCTCACGGATATTGAAGGAACCACAAGCAGTCTTTCTTTCGTCAAAGAAGTGCTGTTTCC
TTATGCACGCCGCGCCCTCCCCGACTTTGTCCGGGAACACCGTGAACACCCGGACGTGATGCCTTGGTTAGATCAAGTCG
CCAACGAAACCGGCACAGCGTTCTCTGAAGAAGCTCTTGTAGCCACCTTGCAAACGTGGATCGACACGGATAGTAAGCAC
ACCGCACTCAAAGCATTGCAAGGCATGATCTGGACATCCGGCTACCAGAACGGCGATTTCACCGCCCACCTCTACCCGGA
TGCAGTCCAACGGCTGCGCGCCTGGCATGCGGCCAACGTGCCGCTGTACGTGTACTCATCCGGCTCGGTACCGGCACAGC
AACTGTTCTTCCGCCACAGTCATGCAGGCGATCTGAGCGGACTGTTCTCAGGTTGGTTCGATACCCAAATCGGTGGCAAG
CGTGAGTCCACCAGCTATCAACGCATTGCGCAACACATTGGGATTGCGCCCGCCGGGATCGTCTTTCTATCGGATGTGAT
CGAAGAATTAAACGCCGCAGCACAAATCGGATTGAACACGGTATTGATTGATCGGCGTGACGATTATCCAACGCCACGTC
ATCTTAAAGACACCGACCGCCATCTGCATTTGGATAGCTTTGCCCAACTGCCCTTTTAA

Upstream 100 bases:

>100_bases
TTACCGAACCGGATGGCTGGGTTGGCCATTTCACCGGCACTGACATTGCACAACGCTTCCCCCGCTATATCCCCGAGGGC
TGCCAAAGCGCGCACTGACA

Downstream 100 bases:

>100_bases
ATCGGCGCGTTATTACCGTCATCCCGGCACCTCAATCCGCAACGACCGCCCAGCAGAACAACAATACCGCTGGCCCGTTG
CATCCTGATAACGCGCTCAA

Product: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase

Products: NA

Alternate protein names: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSMPQAILTDIEGTTSSLSFVKEVLFPYARRALPDFVREHREHPDVMPWLDQVANETGTAFSEEALVATLQTWIDTDSKH
TALKALQGMIWTSGYQNGDFTAHLYPDAVQRLRAWHAANVPLYVYSSGSVPAQQLFFRHSHAGDLSGLFSGWFDTQIGGK
RESTSYQRIAQHIGIAPAGIVFLSDVIEELNAAAQIGLNTVLIDRRDDYPTPRHLKDTDRHLHLDSFAQLPF

Sequences:

>Translated_232_residues
MSMPQAILTDIEGTTSSLSFVKEVLFPYARRALPDFVREHREHPDVMPWLDQVANETGTAFSEEALVATLQTWIDTDSKH
TALKALQGMIWTSGYQNGDFTAHLYPDAVQRLRAWHAANVPLYVYSSGSVPAQQLFFRHSHAGDLSGLFSGWFDTQIGGK
RESTSYQRIAQHIGIAPAGIVFLSDVIEELNAAAQIGLNTVLIDRRDDYPTPRHLKDTDRHLHLDSFAQLPF
>Mature_231_residues
SMPQAILTDIEGTTSSLSFVKEVLFPYARRALPDFVREHREHPDVMPWLDQVANETGTAFSEEALVATLQTWIDTDSKHT
ALKALQGMIWTSGYQNGDFTAHLYPDAVQRLRAWHAANVPLYVYSSGSVPAQQLFFRHSHAGDLSGLFSGWFDTQIGGKR
ESTSYQRIAQHIGIAPAGIVFLSDVIEELNAAAQIGLNTVLIDRRDDYPTPRHLKDTDRHLHLDSFAQLPF

Specific function: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone

COG id: COG4229

COG function: function code C; Predicted enolase-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. MasA/mtnC family

Homologues:

Organism=Homo sapiens, GI10864017, Length=247, Percent_Identity=34.8178137651822, Blast_Score=141, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI115533232, Length=217, Percent_Identity=41.9354838709677, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6320797, Length=214, Percent_Identity=35.5140186915888, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI281360080, Length=213, Percent_Identity=40.3755868544601, Blast_Score=156, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24644163, Length=213, Percent_Identity=40.3755868544601, Blast_Score=156, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTNC_XYLF2 (B2I5X4)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001830037.1
- ProteinModelPortal:   B2I5X4
- SMR:   B2I5X4
- GeneID:   6202210
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_1345
- HOGENOM:   HBG294242
- OMA:   TTDLNFI
- ProtClustDB:   CLSK866737
- HAMAP:   MF_01681
- InterPro:   IPR005834
- InterPro:   IPR010041
- InterPro:   IPR023214
- InterPro:   IPR006439
- Gene3D:   G3DSA:3.40.50.1000
- PANTHER:   PTHR20371
- TIGRFAMs:   TIGR01691
- TIGRFAMs:   TIGR01549

Pfam domain/function: PF00702 Hydrolase; SSF56784 SSF56784

EC number: =3.1.3.77

Molecular weight: Translated: 25992; Mature: 25861

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMPQAILTDIEGTTSSLSFVKEVLFPYARRALPDFVREHREHPDVMPWLDQVANETGTA
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
FSEEALVATLQTWIDTDSKHTALKALQGMIWTSGYQNGDFTAHLYPDAVQRLRAWHAANV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHCCC
PLYVYSSGSVPAQQLFFRHSHAGDLSGLFSGWFDTQIGGKRESTSYQRIAQHIGIAPAGI
CEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHH
VFLSDVIEELNAAAQIGLNTVLIDRRDDYPTPRHLKDTDRHLHLDSFAQLPF
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEECHHHHHCCCC
>Mature Secondary Structure 
SMPQAILTDIEGTTSSLSFVKEVLFPYARRALPDFVREHREHPDVMPWLDQVANETGTA
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
FSEEALVATLQTWIDTDSKHTALKALQGMIWTSGYQNGDFTAHLYPDAVQRLRAWHAANV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHCCC
PLYVYSSGSVPAQQLFFRHSHAGDLSGLFSGWFDTQIGGKRESTSYQRIAQHIGIAPAGI
CEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHH
VFLSDVIEELNAAAQIGLNTVLIDRRDDYPTPRHLKDTDRHLHLDSFAQLPF
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEECHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA