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The map label for this gene is coaX

Identifier: 182681679

GI number: 182681679

Start: 1283938

End: 1284666

Strand: Direct

Name: coaX

Synonym: XfasM23_1137

Alternate gene names: 182681679

Gene position: 1283938-1284666 (Clockwise)

Preceding gene: 182681678

Following gene: 182681680

Centisome position: 50.63

GC content: 51.03

Gene sequence:

>729_bases
ATGAATGATTGGTTATTCGATCTAGGTAATTCGCGTTTTAAATGTGCATCTCTCAGGGAGGGTGTGATTGGTCCTGTAAC
GGTTTTGCCGTACTTAACAGAAACCATGGACGCGTTTGCGTTACAGGAGCTACCACGTGGTCGTGTGGCTTACTTGGCGA
GTGTCGCTGCTCCGGCTATTACTACACATGTACTCGAAGTATTAAAAATCCACTTCGAGAAAGTCCAGGTGGCAGCAACC
GTCGCTGCATGTGCTGGAGTACGAATTGCCTATGCTCACCCGGAACGTTTTGGAGTGGATAGGTTCTTAGCGTTGCTTGG
TTCGTATGGTGAGGGCAATGTCCTGGTAGTGGGTGTGGGGACAGCATTGACTATTGATTTGTTGGCTGCCAATGGTTGTC
ATCTCGGAGGGCGTATCAGTGCTTCACCGACATTGATGCGCCAAGCGTTGCATGCACGCGCCGAGCAACTCCCCCTCAGT
GGTGGGAACTACTTGGAGTTTGCGGAAGATACAGAGGATGCGTTGGTGTCAGGGTGCAATGGTGCAGCGGTGGCATTGAT
CGAACGTAGCCTGTATGAGGCACATCAACGTTTGGACCAGTCGGTTCGATTATTGTTGCATGGTGGAGGTGTAGCATCTT
TATTGCCTTGGTTGGGCGACGTGGTACATCGTCCTAAATTAGTATTGGATGGCCTGGCGATCTGGGCTGCCGTTGCGGCT
AACGTTTAG

Upstream 100 bases:

>100_bases
TTGGTATTGCGCGTGGTTTGGCCGCCGATGGTGCACTCTTGGTAGAAATTAACGGCGTGTTGCGTCCTTTTCATACTGGC
CAAGTTTCGGTCAGACCGAT

Downstream 100 bases:

>100_bases
AATCGTCTCTATGCTTGTGCGTGCGCTCATTTTAGTTTTGGTTGTCCTCAATTTTGGCGTAGCACTCTGGTGGAGGAACC
AGTCGGCACCAAAGGTGCCT

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MNDWLFDLGNSRFKCASLREGVIGPVTVLPYLTETMDAFALQELPRGRVAYLASVAAPAITTHVLEVLKIHFEKVQVAAT
VAACAGVRIAYAHPERFGVDRFLALLGSYGEGNVLVVGVGTALTIDLLAANGCHLGGRISASPTLMRQALHARAEQLPLS
GGNYLEFAEDTEDALVSGCNGAAVALIERSLYEAHQRLDQSVRLLLHGGGVASLLPWLGDVVHRPKLVLDGLAIWAAVAA
NV

Sequences:

>Translated_242_residues
MNDWLFDLGNSRFKCASLREGVIGPVTVLPYLTETMDAFALQELPRGRVAYLASVAAPAITTHVLEVLKIHFEKVQVAAT
VAACAGVRIAYAHPERFGVDRFLALLGSYGEGNVLVVGVGTALTIDLLAANGCHLGGRISASPTLMRQALHARAEQLPLS
GGNYLEFAEDTEDALVSGCNGAAVALIERSLYEAHQRLDQSVRLLLHGGGVASLLPWLGDVVHRPKLVLDGLAIWAAVAA
NV
>Mature_242_residues
MNDWLFDLGNSRFKCASLREGVIGPVTVLPYLTETMDAFALQELPRGRVAYLASVAAPAITTHVLEVLKIHFEKVQVAAT
VAACAGVRIAYAHPERFGVDRFLALLGSYGEGNVLVVGVGTALTIDLLAANGCHLGGRISASPTLMRQALHARAEQLPLS
GGNYLEFAEDTEDALVSGCNGAAVALIERSLYEAHQRLDQSVRLLLHGGGVASLLPWLGDVVHRPKLVLDGLAIWAAVAA
NV

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_XYLF2 (B2I5C0)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001829839.1
- ProteinModelPortal:   B2I5C0
- SMR:   B2I5C0
- GeneID:   6203672
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_1137
- HOGENOM:   HBG634537
- OMA:   CRIVSVR
- ProtClustDB:   PRK13327
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 25686; Mature: 25686

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: ACT_SITE 100-100 BINDING 91-91 BINDING 121-121 BINDING 171-171

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDWLFDLGNSRFKCASLREGVIGPVTVLPYLTETMDAFALQELPRGRVAYLASVAAPAI
CCCCEEECCCCCEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
TTHVLEVLKIHFEKVQVAATVAACAGVRIAYAHPERFGVDRFLALLGSYGEGNVLVVGVG
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHCHHHHHHHHCCCCCCCEEEEECC
TALTIDLLAANGCHLGGRISASPTLMRQALHARAEQLPLSGGNYLEFAEDTEDALVSGCN
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHCCCC
GAAVALIERSLYEAHQRLDQSVRLLLHGGGVASLLPWLGDVVHRPKLVLDGLAIWAAVAA
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
NV
CC
>Mature Secondary Structure
MNDWLFDLGNSRFKCASLREGVIGPVTVLPYLTETMDAFALQELPRGRVAYLASVAAPAI
CCCCEEECCCCCEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
TTHVLEVLKIHFEKVQVAATVAACAGVRIAYAHPERFGVDRFLALLGSYGEGNVLVVGVG
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHCHHHHHHHHCCCCCCCEEEEECC
TALTIDLLAANGCHLGGRISASPTLMRQALHARAEQLPLSGGNYLEFAEDTEDALVSGCN
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHCCCC
GAAVALIERSLYEAHQRLDQSVRLLLHGGGVASLLPWLGDVVHRPKLVLDGLAIWAAVAA
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
NV
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA