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The map label for this gene is cobC [H]

Identifier: 182681506

GI number: 182681506

Start: 1127237

End: 1127881

Strand: Direct

Name: cobC [H]

Synonym: XfasM23_0960

Alternate gene names: 182681506

Gene position: 1127237-1127881 (Clockwise)

Preceding gene: 182681505

Following gene: 182681507

Centisome position: 44.45

GC content: 50.23

Gene sequence:

>645_bases
ATGCGTATTTTGCTTGCTCGGCATGGAGAGACACTTTGGAATGCTGAAGGTCGCTATCAAGGCCAAATTGATATTCCTCT
TTCTTCTGTTGGTGAGGCTCAGGCGCGTGCCCTTGGTGAGCGCCTACGGGATGTAGTCATTGCTCGTGCCGTGGCGTCCC
CCTTACTACGGGCCCAATACACTGCACAACTGGCCTTGGGTGAAAGCCGCATAGCACAGTTATTGATTGAGCCGGATCTG
AAAGAAATTGCCCACGGTGACTGGGAGGGCCTTTTAGATACTGAGATTCATGCAATGGATCCCACACGGCTGCACGCTTG
GCGTAAAGCACCTGAGACAGTCATCATGCCTAACGGTGAATCACTGCACCAAGTCCTAGAACGCAGCTGGCGTGGTTTAA
CAACCGCCGCTGTTGGATTAGGGATTGACGATATCTTATTAGTCGTTGCGCATGATGCAGTCAACCGAGTGATCCTATGT
CGAGTGCTGGGATTGCCATTGGCTCATTTATGGCGCTTCCATCAAGCACCGACTACGCTGAACCTCTTGGAAGGAAAGAA
TATTGACCAACTACAAGTAGTACGCTTAAACGATTGCAGTCATCACACCCCGTTCTTTGGTGAAGCTAAACATCGCGCTT
TATAA

Upstream 100 bases:

>100_bases
ATTTGTATCGTTAAACTGCTGCAAAATACAGCAGATATTCTTTCAGCCGCCGTCATTGCGGTGATGGCGGCTTTCCCATC
ATTAAGAGACTTTTTATAGC

Downstream 100 bases:

>100_bases
GCGCCCACCTGATGGACATAATATGCATTATGTGAACTTTCATTACTGAACTTTCACTTATTGACTGTGCTTGAGACCTG
TTAGGGCAGGTTATACTTGT

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: Alpha-ribazole-5'-phosphate phosphatase [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MRILLARHGETLWNAEGRYQGQIDIPLSSVGEAQARALGERLRDVVIARAVASPLLRAQYTAQLALGESRIAQLLIEPDL
KEIAHGDWEGLLDTEIHAMDPTRLHAWRKAPETVIMPNGESLHQVLERSWRGLTTAAVGLGIDDILLVVAHDAVNRVILC
RVLGLPLAHLWRFHQAPTTLNLLEGKNIDQLQVVRLNDCSHHTPFFGEAKHRAL

Sequences:

>Translated_214_residues
MRILLARHGETLWNAEGRYQGQIDIPLSSVGEAQARALGERLRDVVIARAVASPLLRAQYTAQLALGESRIAQLLIEPDL
KEIAHGDWEGLLDTEIHAMDPTRLHAWRKAPETVIMPNGESLHQVLERSWRGLTTAAVGLGIDDILLVVAHDAVNRVILC
RVLGLPLAHLWRFHQAPTTLNLLEGKNIDQLQVVRLNDCSHHTPFFGEAKHRAL
>Mature_214_residues
MRILLARHGETLWNAEGRYQGQIDIPLSSVGEAQARALGERLRDVVIARAVASPLLRAQYTAQLALGESRIAQLLIEPDL
KEIAHGDWEGLLDTEIHAMDPTRLHAWRKAPETVIMPNGESLHQVLERSWRGLTTAAVGLGIDDILLVVAHDAVNRVILC
RVLGLPLAHLWRFHQAPTTLNLLEGKNIDQLQVVRLNDCSHHTPFFGEAKHRAL

Specific function: Converts N1-(5-phospho-alpha-D-ribosyl)-5,6- dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6- dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=173, Percent_Identity=32.9479768786127, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790856, Length=169, Percent_Identity=28.4023668639053, Blast_Score=62, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322896, Length=143, Percent_Identity=32.8671328671329, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR017578 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =3.1.3.73 [H]

Molecular weight: Translated: 23839; Mature: 23839

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLARHGETLWNAEGRYQGQIDIPLSSVGEAQARALGERLRDVVIARAVASPLLRAQY
CEEEEEECCCEEECCCCCCCCEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAQLALGESRIAQLLIEPDLKEIAHGDWEGLLDTEIHAMDPTRLHAWRKAPETVIMPNGE
HHHHHHCHHHHHHHHHCCCHHHHHCCCCCCCCCCEEECCCCHHHHHHHCCCCEEECCCCH
SLHQVLERSWRGLTTAAVGLGIDDILLVVAHDAVNRVILCRVLGLPLAHLWRFHQAPTTL
HHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEE
NLLEGKNIDQLQVVRLNDCSHHTPFFGEAKHRAL
EECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRILLARHGETLWNAEGRYQGQIDIPLSSVGEAQARALGERLRDVVIARAVASPLLRAQY
CEEEEEECCCEEECCCCCCCCEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAQLALGESRIAQLLIEPDLKEIAHGDWEGLLDTEIHAMDPTRLHAWRKAPETVIMPNGE
HHHHHHCHHHHHHHHHCCCHHHHHCCCCCCCCCCEEECCCCHHHHHHHCCCCEEECCCCH
SLHQVLERSWRGLTTAAVGLGIDDILLVVAHDAVNRVILCRVLGLPLAHLWRFHQAPTTL
HHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEE
NLLEGKNIDQLQVVRLNDCSHHTPFFGEAKHRAL
EECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]