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The map label for this gene is dtpB [H]

Identifier: 182681501

GI number: 182681501

Start: 1119413

End: 1120945

Strand: Reverse

Name: dtpB [H]

Synonym: XfasM23_0955

Alternate gene names: 182681501

Gene position: 1120945-1119413 (Counterclockwise)

Preceding gene: 182681503

Following gene: 182681499

Centisome position: 44.21

GC content: 41.1

Gene sequence:

>1533_bases
ATGAGCGTCGACACTACCGTGAAAAACAGGGTGTATCCTGCGATACCACCAACACAGCTTCCAGAATTTGAAACTATTTT
TGGCCATCCTAAGCCACTCTGGATGTTATTCATGGCCGAGTTCTGGGAAAGATTTGCGTTCTATGGCATCCGTTGGGCAC
TCACACTATACATTGTCACTCAATTCTTTGATGGAAATGCTATTGGCGAAGGGAATGCAAACAGTACATATGGTGCTTAT
TTAGCGTTGGTTTATGCCAGTGCGATCTTTGGCGGCTTTATAGCAGATCGAATTATTGGTTATCAACGTTCAATTATTAT
TGGTGCCGTTATCATGGCTTGTGGACTATTTCTGATCACAGTACCAAGTAGAACCATGTTTGAGATAGGCCTAGCGACTA
TCGTGATTGGTAATGGCCTTTTTAAACCCAATATTTCGTCGTTGGTTGGGCAATTATATGCTGAAGGTGATACACGTCGT
GATCGTGGTTTTACCATTTTTTATATGGGCATCAATGCTGGTTCTCTTATCTCCCCACTAATAACGAGTTGGCTTGCAGG
ACAAGTATTCGGTACACCGATGCAACAAAACTACAAAGTGGTGTTCATCGCATCAGGAATAGGTATGTTTTTAAGCCTAT
TGTGGTTCTGGATAGGAAAGCGTCAATTAAAAGGGATCGGTTTATCACCAAAAGGTGGGGAAAGTATATTCCGGACGTTT
TTAATCGTCTTTGGGGCACTATTGGCTATTCCACTAGCCTATCTATTATTAGCCAAATTAAACGCTACAACACTGGCATG
GATTCTTGGCCTGCTTTTTGCTGTTTTGGCAACATTATTGATAGTAACCGCATTACGTAATGGGAAGATTCAAAGAGATC
GTGTCATCGCAATGCTGATTATCTTTGTTTTTAATGTCATGTTCTGGATGTTTTTTGAACAAGCAGGAAGTTCTTTCAAC
TTTCTTGCAAAAAATATTGTGGATCGACAAATATTAAGCAATTGGGAGTTCCCTGTTGGATGGTTCCAGTCAGTGAATCC
ACTTGCCATTATTTTACTTGCTCCCATCATTGCGGTTATTTGGTCATTACTTGATAAATATAGAATAGAACCCTCGATTC
CACGTAAGTTTAGTTTTGGTCTGATGTTTAATGGATTCGGATTCTTAATCCTAATGTATGCACTATCTAACCTTTTGAAT
GCATCTAACATGATTCCCTTCTGGTCACTCATCGCTGTCTACGTTATACAGACAGTAGGTGAATTATGCCTTTCTCCTAT
CGGTTTATCGATGGTGACCAAATTGGCACCGGTACGTTTGGTCGGTTTTGCAATGGGCGGGTGGTTCTTATCCACTGCAA
TAGGTAACAATCTTTCCGGTGTTTTCGCAAGTTTTGTGAGTGGTGAAGAAGGGATGACTGTCAGTTCAGCGTTGCGTGGC
TATACCTTCGGTTTCTGGTCACTCATTGGTTCCGGAATACTGCTTTTTCTAATCTCTCCTCTGATTAATCGCTTGATGCA
TGGAGTTAAATAG

Upstream 100 bases:

>100_bases
AGATGAGTTTGACATGAATCTCATCTTTGGTGATGCTCATGTTTTATTCATATAAATCAGTGACCATTCCTTTTCATCCT
GAATATACGAGAGATCTTCA

Downstream 100 bases:

>100_bases
TCGAATAAAACATGATTCGACGATCTTCGCTTTGATGAGCACTCGCACCTACAATTCTTCTGTAGGTGTGAGTACCGGCA
TCGTTACAAATCACAGGTAA

Product: amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MSVDTTVKNRVYPAIPPTQLPEFETIFGHPKPLWMLFMAEFWERFAFYGIRWALTLYIVTQFFDGNAIGEGNANSTYGAY
LALVYASAIFGGFIADRIIGYQRSIIIGAVIMACGLFLITVPSRTMFEIGLATIVIGNGLFKPNISSLVGQLYAEGDTRR
DRGFTIFYMGINAGSLISPLITSWLAGQVFGTPMQQNYKVVFIASGIGMFLSLLWFWIGKRQLKGIGLSPKGGESIFRTF
LIVFGALLAIPLAYLLLAKLNATTLAWILGLLFAVLATLLIVTALRNGKIQRDRVIAMLIIFVFNVMFWMFFEQAGSSFN
FLAKNIVDRQILSNWEFPVGWFQSVNPLAIILLAPIIAVIWSLLDKYRIEPSIPRKFSFGLMFNGFGFLILMYALSNLLN
ASNMIPFWSLIAVYVIQTVGELCLSPIGLSMVTKLAPVRLVGFAMGGWFLSTAIGNNLSGVFASFVSGEEGMTVSSALRG
YTFGFWSLIGSGILLFLISPLINRLMHGVK

Sequences:

>Translated_510_residues
MSVDTTVKNRVYPAIPPTQLPEFETIFGHPKPLWMLFMAEFWERFAFYGIRWALTLYIVTQFFDGNAIGEGNANSTYGAY
LALVYASAIFGGFIADRIIGYQRSIIIGAVIMACGLFLITVPSRTMFEIGLATIVIGNGLFKPNISSLVGQLYAEGDTRR
DRGFTIFYMGINAGSLISPLITSWLAGQVFGTPMQQNYKVVFIASGIGMFLSLLWFWIGKRQLKGIGLSPKGGESIFRTF
LIVFGALLAIPLAYLLLAKLNATTLAWILGLLFAVLATLLIVTALRNGKIQRDRVIAMLIIFVFNVMFWMFFEQAGSSFN
FLAKNIVDRQILSNWEFPVGWFQSVNPLAIILLAPIIAVIWSLLDKYRIEPSIPRKFSFGLMFNGFGFLILMYALSNLLN
ASNMIPFWSLIAVYVIQTVGELCLSPIGLSMVTKLAPVRLVGFAMGGWFLSTAIGNNLSGVFASFVSGEEGMTVSSALRG
YTFGFWSLIGSGILLFLISPLINRLMHGVK
>Mature_509_residues
SVDTTVKNRVYPAIPPTQLPEFETIFGHPKPLWMLFMAEFWERFAFYGIRWALTLYIVTQFFDGNAIGEGNANSTYGAYL
ALVYASAIFGGFIADRIIGYQRSIIIGAVIMACGLFLITVPSRTMFEIGLATIVIGNGLFKPNISSLVGQLYAEGDTRRD
RGFTIFYMGINAGSLISPLITSWLAGQVFGTPMQQNYKVVFIASGIGMFLSLLWFWIGKRQLKGIGLSPKGGESIFRTFL
IVFGALLAIPLAYLLLAKLNATTLAWILGLLFAVLATLLIVTALRNGKIQRDRVIAMLIIFVFNVMFWMFFEQAGSSFNF
LAKNIVDRQILSNWEFPVGWFQSVNPLAIILLAPIIAVIWSLLDKYRIEPSIPRKFSFGLMFNGFGFLILMYALSNLLNA
SNMIPFWSLIAVYVIQTVGELCLSPIGLSMVTKLAPVRLVGFAMGGWFLSTAIGNNLSGVFASFVSGEEGMTVSSALRGY
TFGFWSLIGSGILLFLISPLINRLMHGVK

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpB subfamily [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=391, Percent_Identity=26.5984654731458, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI226371746, Length=375, Percent_Identity=29.3333333333333, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI226371748, Length=365, Percent_Identity=27.9452054794521, Blast_Score=86, Evalue=9e-17,
Organism=Escherichia coli, GI1789911, Length=486, Percent_Identity=31.8930041152263, Blast_Score=228, Evalue=1e-60,
Organism=Escherichia coli, GI1787922, Length=490, Percent_Identity=30.4081632653061, Blast_Score=208, Evalue=7e-55,
Organism=Escherichia coli, GI1790572, Length=480, Percent_Identity=30, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1786927, Length=452, Percent_Identity=28.3185840707965, Blast_Score=153, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI71987453, Length=380, Percent_Identity=23.1578947368421, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17569141, Length=364, Percent_Identity=25.8241758241758, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17541704, Length=385, Percent_Identity=25.1948051948052, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28571098, Length=343, Percent_Identity=24.7813411078717, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28571102, Length=375, Percent_Identity=24.5333333333333, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI28571100, Length=375, Percent_Identity=24.5333333333333, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24639583, Length=343, Percent_Identity=25.6559766763848, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24639585, Length=343, Percent_Identity=25.6559766763848, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24639581, Length=343, Percent_Identity=25.6559766763848, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 56393; Mature: 56262

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVDTTVKNRVYPAIPPTQLPEFETIFGHPKPLWMLFMAEFWERFAFYGIRWALTLYIVT
CCCCCCHHCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFFDGNAIGEGNANSTYGAYLALVYASAIFGGFIADRIIGYQRSIIIGAVIMACGLFLIT
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VPSRTMFEIGLATIVIGNGLFKPNISSLVGQLYAEGDTRRDRGFTIFYMGINAGSLISPL
CCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHH
ITSWLAGQVFGTPMQQNYKVVFIASGIGMFLSLLWFWIGKRQLKGIGLSPKGGESIFRTF
HHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LIVFGALLAIPLAYLLLAKLNATTLAWILGLLFAVLATLLIVTALRNGKIQRDRVIAMLI
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
IFVFNVMFWMFFEQAGSSFNFLAKNIVDRQILSNWEFPVGWFQSVNPLAIILLAPIIAVI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHH
WSLLDKYRIEPSIPRKFSFGLMFNGFGFLILMYALSNLLNASNMIPFWSLIAVYVIQTVG
HHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
ELCLSPIGLSMVTKLAPVRLVGFAMGGWFLSTAIGNNLSGVFASFVSGEEGMTVSSALRG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHH
YTFGFWSLIGSGILLFLISPLINRLMHGVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVDTTVKNRVYPAIPPTQLPEFETIFGHPKPLWMLFMAEFWERFAFYGIRWALTLYIVT
CCCCCHHCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFFDGNAIGEGNANSTYGAYLALVYASAIFGGFIADRIIGYQRSIIIGAVIMACGLFLIT
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VPSRTMFEIGLATIVIGNGLFKPNISSLVGQLYAEGDTRRDRGFTIFYMGINAGSLISPL
CCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHH
ITSWLAGQVFGTPMQQNYKVVFIASGIGMFLSLLWFWIGKRQLKGIGLSPKGGESIFRTF
HHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LIVFGALLAIPLAYLLLAKLNATTLAWILGLLFAVLATLLIVTALRNGKIQRDRVIAMLI
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
IFVFNVMFWMFFEQAGSSFNFLAKNIVDRQILSNWEFPVGWFQSVNPLAIILLAPIIAVI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHH
WSLLDKYRIEPSIPRKFSFGLMFNGFGFLILMYALSNLLNASNMIPFWSLIAVYVIQTVG
HHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
ELCLSPIGLSMVTKLAPVRLVGFAMGGWFLSTAIGNNLSGVFASFVSGEEGMTVSSALRG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHH
YTFGFWSLIGSGILLFLISPLINRLMHGVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA