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The map label for this gene is gpmA

Identifier: 182681499

GI number: 182681499

Start: 1117682

End: 1118431

Strand: Reverse

Name: gpmA

Synonym: XfasM23_0953

Alternate gene names: 182681499

Gene position: 1118431-1117682 (Counterclockwise)

Preceding gene: 182681501

Following gene: 182681481

Centisome position: 44.11

GC content: 45.87

Gene sequence:

>750_bases
ATGACTCGTAAACTTGTATTGCTACGCCATGGACAGAGTCAATGGAACTCAATGAACCGTTTTACTGGCTGGGTGGATAT
AGGGCTGACCGAACAAGGTCATCAAGAAGCCACTATGGCTGGTCATCTGATGAAAAAAGAAGGACTAGAGTTTGATGTCG
CTCATACTTCTTTACTTAAGCGGGCGATCCATACATTACAAGACGCACTTAAAGCATTGGACCAGGACTGGTTACCAATT
TATAAAAGCTGGCGTCTCAATGAGCGTCACTACGGTGCTCTACAAGGCCTTGATAAAATAGATACCGCAGCTAAACATGG
TGAAGAGCAAGTCAATATTTGGCGCCGCTCCTATGACATCCAGCCGCCACCGATTGATCTAGATGACCCAAGCCATCCAA
TGCGAGACCGCCGTTACGCCGCTTTGGACCGCAAAGTATTACCTGTGAGGGAATCGCTGAAAAATACACTCGAACGAGTA
TTACCGTACTGGAATGATGCCATCGCACCACAACTAAATGACAACAAGACGGTACTTATTAGCGCCCACGGCAACTCATT
GCGTGCGTTGTACAAGTACCTTAATAAAGAAAGTGATGAGAAAATCCTAAATGTCAATATCCCTACTGGCATTCCACTTC
TATTTGAACTGAGCGATACACTACAAGTAGTGAGTTACCGTTACCTTGGCGATCCAGATGCAGCACAACGCGCTGCCGAA
ATGGTAGCAAACCAAGGTAAGGCGAAGTAA

Upstream 100 bases:

>100_bases
AAATACCATCATGCCTATATCAGATATTAAGAGCGTATACAGGCAATCTCGACCTGACGTTACAATCATGTTTTAGATAC
TTTCAATTCAGGAAAGCCGC

Downstream 100 bases:

>100_bases
TACGCAGTTTTTCACGATCACAATAAATACAGGCGTACTACCGAAACGCTAGACTGCAATAAAAACTTTGACTAAGCAGT
TGTGGTAGGTATCGGAGTAT

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MTRKLVLLRHGQSQWNSMNRFTGWVDIGLTEQGHQEATMAGHLMKKEGLEFDVAHTSLLKRAIHTLQDALKALDQDWLPI
YKSWRLNERHYGALQGLDKIDTAAKHGEEQVNIWRRSYDIQPPPIDLDDPSHPMRDRRYAALDRKVLPVRESLKNTLERV
LPYWNDAIAPQLNDNKTVLISAHGNSLRALYKYLNKESDEKILNVNIPTGIPLLFELSDTLQVVSYRYLGDPDAAQRAAE
MVANQGKAK

Sequences:

>Translated_249_residues
MTRKLVLLRHGQSQWNSMNRFTGWVDIGLTEQGHQEATMAGHLMKKEGLEFDVAHTSLLKRAIHTLQDALKALDQDWLPI
YKSWRLNERHYGALQGLDKIDTAAKHGEEQVNIWRRSYDIQPPPIDLDDPSHPMRDRRYAALDRKVLPVRESLKNTLERV
LPYWNDAIAPQLNDNKTVLISAHGNSLRALYKYLNKESDEKILNVNIPTGIPLLFELSDTLQVVSYRYLGDPDAAQRAAE
MVANQGKAK
>Mature_248_residues
TRKLVLLRHGQSQWNSMNRFTGWVDIGLTEQGHQEATMAGHLMKKEGLEFDVAHTSLLKRAIHTLQDALKALDQDWLPIY
KSWRLNERHYGALQGLDKIDTAAKHGEEQVNIWRRSYDIQPPPIDLDDPSHPMRDRRYAALDRKVLPVRESLKNTLERVL
PYWNDAIAPQLNDNKTVLISAHGNSLRALYKYLNKESDEKILNVNIPTGIPLLFELSDTLQVVSYRYLGDPDAAQRAAEM
VANQGKAK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily

Homologues:

Organism=Homo sapiens, GI50593010, Length=251, Percent_Identity=52.191235059761, Blast_Score=276, Evalue=1e-74,
Organism=Homo sapiens, GI4505753, Length=249, Percent_Identity=53.8152610441767, Blast_Score=264, Evalue=5e-71,
Organism=Homo sapiens, GI4502445, Length=251, Percent_Identity=50.996015936255, Blast_Score=256, Evalue=1e-68,
Organism=Homo sapiens, GI40353764, Length=251, Percent_Identity=50.996015936255, Blast_Score=256, Evalue=1e-68,
Organism=Homo sapiens, GI71274132, Length=249, Percent_Identity=51.8072289156626, Blast_Score=252, Evalue=2e-67,
Organism=Homo sapiens, GI310129614, Length=161, Percent_Identity=57.1428571428571, Blast_Score=177, Evalue=9e-45,
Organism=Escherichia coli, GI1786970, Length=246, Percent_Identity=56.5040650406504, Blast_Score=290, Evalue=7e-80,
Organism=Saccharomyces cerevisiae, GI6322697, Length=244, Percent_Identity=54.0983606557377, Blast_Score=253, Evalue=2e-68,
Organism=Saccharomyces cerevisiae, GI6324516, Length=297, Percent_Identity=33.3333333333333, Blast_Score=145, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6320183, Length=299, Percent_Identity=34.1137123745819, Blast_Score=144, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6324857, Length=108, Percent_Identity=32.4074074074074, Blast_Score=62, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24646216, Length=250, Percent_Identity=50.8, Blast_Score=268, Evalue=3e-72,
Organism=Drosophila melanogaster, GI85725270, Length=250, Percent_Identity=52.4, Blast_Score=254, Evalue=5e-68,
Organism=Drosophila melanogaster, GI85725272, Length=250, Percent_Identity=52.4, Blast_Score=254, Evalue=5e-68,
Organism=Drosophila melanogaster, GI24650981, Length=250, Percent_Identity=52.4, Blast_Score=254, Evalue=5e-68,
Organism=Drosophila melanogaster, GI28571815, Length=254, Percent_Identity=38.9763779527559, Blast_Score=163, Evalue=1e-40,
Organism=Drosophila melanogaster, GI28571817, Length=254, Percent_Identity=38.9763779527559, Blast_Score=162, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24648979, Length=254, Percent_Identity=38.9763779527559, Blast_Score=162, Evalue=1e-40,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): GPMA_XYLF2 (B2I4U0)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001829659.1
- ProteinModelPortal:   B2I4U0
- SMR:   B2I4U0
- GeneID:   6203426
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_0953
- HOGENOM:   HBG658938
- OMA:   TGWKDPD
- ProtClustDB:   PRK14115
- GO:   GO:0006096
- HAMAP:   MF_01039
- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952
- PANTHER:   PTHR11931
- SMART:   SM00855
- TIGRFAMs:   TIGR01258

Pfam domain/function: PF00300 PGAM

EC number: =5.4.2.1

Molecular weight: Translated: 28513; Mature: 28382

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS00175 PG_MUTASE

Important sites: ACT_SITE 10-10 ACT_SITE 183-183

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKLVLLRHGQSQWNSMNRFTGWVDIGLTEQGHQEATMAGHLMKKEGLEFDVAHTSLLK
CCCEEEEEECCCHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHCCCEEHHHHHHHHH
RAIHTLQDALKALDQDWLPIYKSWRLNERHYGALQGLDKIDTAAKHGEEQVNIWRRSYDI
HHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHCHHHHHHHHHCCHHHHHHHHHHCCC
QPPPIDLDDPSHPMRDRRYAALDRKVLPVRESLKNTLERVLPYWNDAIAPQLNDNKTVLI
CCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEE
SAHGNSLRALYKYLNKESDEKILNVNIPTGIPLLFELSDTLQVVSYRYLGDPDAAQRAAE
EECCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHCCCCHHHHHHHH
MVANQGKAK
HHHHCCCCC
>Mature Secondary Structure 
TRKLVLLRHGQSQWNSMNRFTGWVDIGLTEQGHQEATMAGHLMKKEGLEFDVAHTSLLK
CCEEEEEECCCHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHCCCEEHHHHHHHHH
RAIHTLQDALKALDQDWLPIYKSWRLNERHYGALQGLDKIDTAAKHGEEQVNIWRRSYDI
HHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHCHHHHHHHHHCCHHHHHHHHHHCCC
QPPPIDLDDPSHPMRDRRYAALDRKVLPVRESLKNTLERVLPYWNDAIAPQLNDNKTVLI
CCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEE
SAHGNSLRALYKYLNKESDEKILNVNIPTGIPLLFELSDTLQVVSYRYLGDPDAAQRAAE
EECCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHCCCCHHHHHHHH
MVANQGKAK
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA