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The map label for this gene is csd [H]

Identifier: 182681281

GI number: 182681281

Start: 854988

End: 856238

Strand: Reverse

Name: csd [H]

Synonym: XfasM23_0726

Alternate gene names: 182681281

Gene position: 856238-854988 (Counterclockwise)

Preceding gene: 182681282

Following gene: 182681280

Centisome position: 33.77

GC content: 57.47

Gene sequence:

>1251_bases
ATGGACCGTATAAACACCTCCGCAGCCCCCCCCACATCCCCCGATTGGGAACGCCTGCGTGCCGACTTCCCCCTACTGCA
ACGCCACGTACACGGAAAACCGCTGATCTATTTCGACAACGCAAATACCGCACAAAAACCCCAGGCAGTGATCACTGCCA
CCGACACCTTCTACCGCCGCCACAACGCCAACATCAGCCGTGCCGTACACACACTAGGCACCGAAGCCACAGAAGCCTAC
GAAGCCACACGAGCAGCACTGGCAACCCTACTTAACGTCCCCATGCACGAACTGGTGCTATGCAGCGGCACGACCTTCGC
CATCAACCTCATTGCCTACTCATGGGCACTGCCACGACTGCGTACCGGCGACGTGATCCTAGTCTCACGGATGGAACACC
ACGCCAACATCGTCCCCTGGCAATTGATCGCTGAACGTACCGGCGCACGTATCCAAGTCGCCGACATCCTGCCTAACGGC
ACCTTGGATCTAGATGCCCTGCATACCCTGATGACACCCCAAGTCAAACTGCTGGCCATCACGCATGTGTCCAACGTCCT
GGGCACCGTTAACCCGATACACGACATCTGCCGCCAAGCACGGCAACGCGGCATTACGACCGTCGTCGACGGCTCCCAAG
CGGCACCACATCGCCACATTAATATTCCGGCCATCGGCTGCGACTTCTATGCCATCACCGGACACAAACTCTACGGCCCC
ACAGGAACCGGAGCATTATGGGCACGCCGCGAACACCTCCACATCATGCCGCCATTTCTAGGTGGCGGAGAAATGATTAA
AGAAGTGAGTTTTGACGGTACCCTCTTCAACACCCCACCACATAAATTTGAAGCAGGCACCCCCAACATTGCCGGCTTCA
TCGGCCTCAGCGCCGCCGTAGATTACGTGCGTCGTATCGGAATCGACCAGATCGAAACACGCGAAACAGAACTACTGGCG
CATCTCACCGAAGAACTACAGAAAATCGACGGCATGCGACTCTTCGGCACCGCACCCAACAAAGCCGCCGTGGTTTCCTT
CATGATCGAAGGCACACACGCCCACGACCTGGCCACACTGCTCGACCTGGAAGGCGTTGCCGTACGCTCTGGTCAACACT
GTGCACACCCCCTCCTGCAATACTACGGAGTGACCGCCACCTGCCGCGCCTCACTGGCGTTCTACAACACTCACGAAGAG
ATAGAACGCTTCATCACGGCCCTGCTCAAAGTACGCAAACTACTAGGCTGA

Upstream 100 bases:

>100_bases
AGCTCCTCAGCGCAGCGTTCTGCCACGAACCACTAACCCTGTTAGACAGCACCCTAGCCGACATCCTGCGCGCACCACTG
AATCACGCACTGAACAGCAC

Downstream 100 bases:

>100_bases
CCCGCATCCCTGCATCTCCCCTGACGCCTCACCACCACGGCACCATTCCACAGCACGACAATACTTGCCCGAACACATTT
GAAAAATTTTTTGGAACCCA

Product: SufS subfamily cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MDRINTSAAPPTSPDWERLRADFPLLQRHVHGKPLIYFDNANTAQKPQAVITATDTFYRRHNANISRAVHTLGTEATEAY
EATRAALATLLNVPMHELVLCSGTTFAINLIAYSWALPRLRTGDVILVSRMEHHANIVPWQLIAERTGARIQVADILPNG
TLDLDALHTLMTPQVKLLAITHVSNVLGTVNPIHDICRQARQRGITTVVDGSQAAPHRHINIPAIGCDFYAITGHKLYGP
TGTGALWARREHLHIMPPFLGGGEMIKEVSFDGTLFNTPPHKFEAGTPNIAGFIGLSAAVDYVRRIGIDQIETRETELLA
HLTEELQKIDGMRLFGTAPNKAAVVSFMIEGTHAHDLATLLDLEGVAVRSGQHCAHPLLQYYGVTATCRASLAFYNTHEE
IERFITALLKVRKLLG

Sequences:

>Translated_416_residues
MDRINTSAAPPTSPDWERLRADFPLLQRHVHGKPLIYFDNANTAQKPQAVITATDTFYRRHNANISRAVHTLGTEATEAY
EATRAALATLLNVPMHELVLCSGTTFAINLIAYSWALPRLRTGDVILVSRMEHHANIVPWQLIAERTGARIQVADILPNG
TLDLDALHTLMTPQVKLLAITHVSNVLGTVNPIHDICRQARQRGITTVVDGSQAAPHRHINIPAIGCDFYAITGHKLYGP
TGTGALWARREHLHIMPPFLGGGEMIKEVSFDGTLFNTPPHKFEAGTPNIAGFIGLSAAVDYVRRIGIDQIETRETELLA
HLTEELQKIDGMRLFGTAPNKAAVVSFMIEGTHAHDLATLLDLEGVAVRSGQHCAHPLLQYYGVTATCRASLAFYNTHEE
IERFITALLKVRKLLG
>Mature_416_residues
MDRINTSAAPPTSPDWERLRADFPLLQRHVHGKPLIYFDNANTAQKPQAVITATDTFYRRHNANISRAVHTLGTEATEAY
EATRAALATLLNVPMHELVLCSGTTFAINLIAYSWALPRLRTGDVILVSRMEHHANIVPWQLIAERTGARIQVADILPNG
TLDLDALHTLMTPQVKLLAITHVSNVLGTVNPIHDICRQARQRGITTVVDGSQAAPHRHINIPAIGCDFYAITGHKLYGP
TGTGALWARREHLHIMPPFLGGGEMIKEVSFDGTLFNTPPHKFEAGTPNIAGFIGLSAAVDYVRRIGIDQIETRETELLA
HLTEELQKIDGMRLFGTAPNKAAVVSFMIEGTHAHDLATLLDLEGVAVRSGQHCAHPLLQYYGVTATCRASLAFYNTHEE
IERFITALLKVRKLLG

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=398, Percent_Identity=22.1105527638191, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI156713448, Length=329, Percent_Identity=22.7963525835866, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1787970, Length=402, Percent_Identity=47.5124378109453, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI1789175, Length=399, Percent_Identity=41.6040100250627, Blast_Score=305, Evalue=3e-84,
Organism=Escherichia coli, GI48994898, Length=408, Percent_Identity=28.4313725490196, Blast_Score=111, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI25143064, Length=230, Percent_Identity=26.9565217391304, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI193211090, Length=298, Percent_Identity=25.1677852348993, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319831, Length=397, Percent_Identity=25.4408060453401, Blast_Score=103, Evalue=5e-23,
Organism=Drosophila melanogaster, GI20129463, Length=261, Percent_Identity=27.5862068965517, Blast_Score=105, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 45783; Mature: 45783

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRINTSAAPPTSPDWERLRADFPLLQRHVHGKPLIYFDNANTAQKPQAVITATDTFYRR
CCCCCCCCCCCCCCCHHHHHCCCHHHHHHCCCCCEEEECCCCCCCCCCEEEEEHHHHHHH
HNANISRAVHTLGTEATEAYEATRAALATLLNVPMHELVLCSGTTFAINLIAYSWALPRL
HCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHEEEECCCCEEEEHHHHHHCCCCC
RTGDVILVSRMEHHANIVPWQLIAERTGARIQVADILPNGTLDLDALHTLMTPQVKLLAI
CCCCEEEEEEHHHCCCCCHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHCCCEEEEEH
THVSNVLGTVNPIHDICRQARQRGITTVVDGSQAAPHRHINIPAIGCDFYAITGHKLYGP
HHHHHHHHCCCHHHHHHHHHHHCCCEEEECCCCCCCCCEECCCEECCCEEEEECCEEECC
TGTGALWARREHLHIMPPFLGGGEMIKEVSFDGTLFNTPPHKFEAGTPNIAGFIGLSAAV
CCCCHHHEECCCCEECCCCCCCHHHHHHHCCCCEEECCCCCCCCCCCCCHHHHHHHHHHH
DYVRRIGIDQIETRETELLAHLTEELQKIDGMRLFGTAPNKAAVVSFMIEGTHAHDLATL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHEEEEEEECCCCHHHHHHH
LDLEGVAVRSGQHCAHPLLQYYGVTATCRASLAFYNTHEEIERFITALLKVRKLLG
HHCCCEEECCCCHHHHHHHHHHCCCHHHHHHHEEECCHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MDRINTSAAPPTSPDWERLRADFPLLQRHVHGKPLIYFDNANTAQKPQAVITATDTFYRR
CCCCCCCCCCCCCCCHHHHHCCCHHHHHHCCCCCEEEECCCCCCCCCCEEEEEHHHHHHH
HNANISRAVHTLGTEATEAYEATRAALATLLNVPMHELVLCSGTTFAINLIAYSWALPRL
HCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHEEEECCCCEEEEHHHHHHCCCCC
RTGDVILVSRMEHHANIVPWQLIAERTGARIQVADILPNGTLDLDALHTLMTPQVKLLAI
CCCCEEEEEEHHHCCCCCHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHCCCEEEEEH
THVSNVLGTVNPIHDICRQARQRGITTVVDGSQAAPHRHINIPAIGCDFYAITGHKLYGP
HHHHHHHHCCCHHHHHHHHHHHCCCEEEECCCCCCCCCEECCCEECCCEEEEECCEEECC
TGTGALWARREHLHIMPPFLGGGEMIKEVSFDGTLFNTPPHKFEAGTPNIAGFIGLSAAV
CCCCHHHEECCCCEECCCCCCCHHHHHHHCCCCEEECCCCCCCCCCCCCHHHHHHHHHHH
DYVRRIGIDQIETRETELLAHLTEELQKIDGMRLFGTAPNKAAVVSFMIEGTHAHDLATL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHEEEEEEECCCCHHHHHHH
LDLEGVAVRSGQHCAHPLLQYYGVTATCRASLAFYNTHEEIERFITALLKVRKLLG
HHCCCEEECCCCHHHHHHHHHHCCCHHHHHHHEEECCHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]