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The map label for this gene is nagA [H]

Identifier: 182681274

GI number: 182681274

Start: 847870

End: 849027

Strand: Direct

Name: nagA [H]

Synonym: XfasM23_0719

Alternate gene names: 182681274

Gene position: 847870-849027 (Clockwise)

Preceding gene: 182681273

Following gene: 182681275

Centisome position: 33.44

GC content: 58.29

Gene sequence:

>1158_bases
ATGGGTGTTTCTTCTGGCATCACAGGGTTCATCAATGGCCGCATTCTGACCGATACCGGGTTCCGTCATGATCTGGCGGT
GTTGTTGCGTGAGGGCAGCATTCACGCACTGGTGCCACATGATGATCCGTGGGTGATGGAGGTTGCGCAGTGGGTGGACT
TGCAGGGAGGTCTGTTGCTGCCTGGGTTTATCGATATTCAGGTGAATGGCGGCGGCGGCGTGCTGTTCAATAATGCGCGT
GATGTGGATGGCTTGGCCACAATTGCGCGTGCGCACCGTCGCTACGGGACGACGGGACTGTTACCCACATTGATTAGTGA
CACTGTGGAGGTGATGGCTGAGGCCATTGCTGCCACGCGTGCCGCGATTGCTCAGGGGGTACCGGGAATCCTGGGGATTC
ACTTGGAAGGCCCTTACCTCAATCCCCTGCGTAAAGGGATCCATGACCATACTCAATTCCGTGTGCCGCAGTTGCATGAG
CTGATGCGGTGCACGGCATTGGATAACGGGGTGACTCTGGTGACGTTGGCGCCTGAGCAGGTGCCGGTTGAGATGATTCG
TGTTTTTGTCGAGCGTGGTGCGATCGTCTTTGCCGGGCATACCGCAGCGACGTATGAGCAAGTGCGGGCTGGCATTGCAG
CGGGTGTCACAGGGTTTACGCATCTGTACAACGCGATGTCGCAGTTAGTCGGGCGCGAGCCGAATGTGGTGGGTGCTGCG
CTGGAAGATCCGAATACATGGTGCGGGATCATTGTTGATGGCGTACACGTACATCCGGCGAGTCTGCGTGTGGCCTTAGC
CGCCAAGCCGCGCGGTAAGGTGCTGCTGGTGACCGATGCGATGCCACCAGTTGGCAGTGACAGTGTTCACTATGATCTCT
ATGGTGAAACGATTACGGTGATGGATGGTGTGGTCCGTAATGCGGCTGGTGCGTTGGCGGGTGCCGCGCTGGATATGGCA
ACGGCGGTGCGCAATACGGTGCATTGGTTGGGTGTTGATTTGGCTGAGGCTGTGCGCATGGCCTCGACCTATCCGGCGCA
GTGCATTGGGTTAGGGGATCGTCTGGGGAGGATTGCGCCTGGTTATCAAGCCGACCTGGTGTGGGTTGATGACGACGTGC
AGGTACAGGGCACGTGGATTGCTGGTGTGGGCGCTTGA

Upstream 100 bases:

>100_bases
CGATCCAGAGTTTTTATCGCGCCATTAATACGCTGGCATTATGCCGAGGGTATAACCCTGATCTGCCACCACATTTGAAA
AAAGTCACGGAAACGGTGTG

Downstream 100 bases:

>100_bases
GTCTCTAGGGTGAGTAAGTGCACGGTTGCTTGGGTAACAGCAGTGGGGTTAGGGCGGTCATGGTGTGCATTGTTTGAGCT
GTGCCAATACGGATCACGCT

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MGVSSGITGFINGRILTDTGFRHDLAVLLREGSIHALVPHDDPWVMEVAQWVDLQGGLLLPGFIDIQVNGGGGVLFNNAR
DVDGLATIARAHRRYGTTGLLPTLISDTVEVMAEAIAATRAAIAQGVPGILGIHLEGPYLNPLRKGIHDHTQFRVPQLHE
LMRCTALDNGVTLVTLAPEQVPVEMIRVFVERGAIVFAGHTAATYEQVRAGIAAGVTGFTHLYNAMSQLVGREPNVVGAA
LEDPNTWCGIIVDGVHVHPASLRVALAAKPRGKVLLVTDAMPPVGSDSVHYDLYGETITVMDGVVRNAAGALAGAALDMA
TAVRNTVHWLGVDLAEAVRMASTYPAQCIGLGDRLGRIAPGYQADLVWVDDDVQVQGTWIAGVGA

Sequences:

>Translated_385_residues
MGVSSGITGFINGRILTDTGFRHDLAVLLREGSIHALVPHDDPWVMEVAQWVDLQGGLLLPGFIDIQVNGGGGVLFNNAR
DVDGLATIARAHRRYGTTGLLPTLISDTVEVMAEAIAATRAAIAQGVPGILGIHLEGPYLNPLRKGIHDHTQFRVPQLHE
LMRCTALDNGVTLVTLAPEQVPVEMIRVFVERGAIVFAGHTAATYEQVRAGIAAGVTGFTHLYNAMSQLVGREPNVVGAA
LEDPNTWCGIIVDGVHVHPASLRVALAAKPRGKVLLVTDAMPPVGSDSVHYDLYGETITVMDGVVRNAAGALAGAALDMA
TAVRNTVHWLGVDLAEAVRMASTYPAQCIGLGDRLGRIAPGYQADLVWVDDDVQVQGTWIAGVGA
>Mature_384_residues
GVSSGITGFINGRILTDTGFRHDLAVLLREGSIHALVPHDDPWVMEVAQWVDLQGGLLLPGFIDIQVNGGGGVLFNNARD
VDGLATIARAHRRYGTTGLLPTLISDTVEVMAEAIAATRAAIAQGVPGILGIHLEGPYLNPLRKGIHDHTQFRVPQLHEL
MRCTALDNGVTLVTLAPEQVPVEMIRVFVERGAIVFAGHTAATYEQVRAGIAAGVTGFTHLYNAMSQLVGREPNVVGAAL
EDPNTWCGIIVDGVHVHPASLRVALAAKPRGKVLLVTDAMPPVGSDSVHYDLYGETITVMDGVVRNAAGALAGAALDMAT
AVRNTVHWLGVDLAEAVRMASTYPAQCIGLGDRLGRIAPGYQADLVWVDDDVQVQGTWIAGVGA

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=377, Percent_Identity=34.2175066312997, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI224922791, Length=376, Percent_Identity=33.5106382978723, Blast_Score=166, Evalue=4e-41,
Organism=Escherichia coli, GI1786892, Length=376, Percent_Identity=39.6276595744681, Blast_Score=254, Evalue=5e-69,
Organism=Caenorhabditis elegans, GI17553768, Length=400, Percent_Identity=29.5, Blast_Score=150, Evalue=8e-37,
Organism=Drosophila melanogaster, GI281361140, Length=408, Percent_Identity=33.0882352941176, Blast_Score=185, Evalue=5e-47,
Organism=Drosophila melanogaster, GI19920392, Length=394, Percent_Identity=33.248730964467, Blast_Score=182, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 40689; Mature: 40558

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVSSGITGFINGRILTDTGFRHDLAVLLREGSIHALVPHDDPWVMEVAQWVDLQGGLLL
CCCCCCCCEEECCEEEECCCCCHHHHHEEECCCEEEECCCCCHHHHHHHHHHCCCCCEEC
PGFIDIQVNGGGGVLFNNARDVDGLATIARAHRRYGTTGLLPTLISDTVEVMAEAIAATR
CEEEEEEEECCCEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
AAIAQGVPGILGIHLEGPYLNPLRKGIHDHTQFRVPQLHELMRCTALDNGVTLVTLAPEQ
HHHHCCCCCEEEEEECCCCCCHHHHCCCHHHCCCCHHHHHHHHHHCCCCCEEEEEECCCC
VPVEMIRVFVERGAIVFAGHTAATYEQVRAGIAAGVTGFTHLYNAMSQLVGREPNVVGAA
CCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
LEDPNTWCGIIVDGVHVHPASLRVALAAKPRGKVLLVTDAMPPVGSDSVHYDLYGETITV
ECCCCCEEEEEEECEEECCCCEEEEEEECCCCCEEEEECCCCCCCCCCEEEEEECCEEHH
MDGVVRNAAGALAGAALDMATAVRNTVHWLGVDLAEAVRMASTYPAQCIGLGDRLGRIAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECHHHHCCCCC
GYQADLVWVDDDVQVQGTWIAGVGA
CCCEEEEEECCCEEEEEEEEEECCC
>Mature Secondary Structure 
GVSSGITGFINGRILTDTGFRHDLAVLLREGSIHALVPHDDPWVMEVAQWVDLQGGLLL
CCCCCCCEEECCEEEECCCCCHHHHHEEECCCEEEECCCCCHHHHHHHHHHCCCCCEEC
PGFIDIQVNGGGGVLFNNARDVDGLATIARAHRRYGTTGLLPTLISDTVEVMAEAIAATR
CEEEEEEEECCCEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
AAIAQGVPGILGIHLEGPYLNPLRKGIHDHTQFRVPQLHELMRCTALDNGVTLVTLAPEQ
HHHHCCCCCEEEEEECCCCCCHHHHCCCHHHCCCCHHHHHHHHHHCCCCCEEEEEECCCC
VPVEMIRVFVERGAIVFAGHTAATYEQVRAGIAAGVTGFTHLYNAMSQLVGREPNVVGAA
CCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
LEDPNTWCGIIVDGVHVHPASLRVALAAKPRGKVLLVTDAMPPVGSDSVHYDLYGETITV
ECCCCCEEEEEEECEEECCCCEEEEEEECCCCCEEEEECCCCCCCCCCEEEEEECCEEHH
MDGVVRNAAGALAGAALDMATAVRNTVHWLGVDLAEAVRMASTYPAQCIGLGDRLGRIAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECHHHHCCCCC
GYQADLVWVDDDVQVQGTWIAGVGA
CCCEEEEEECCCEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]