Click here to switch to the map view.

The map label for this gene is cyoB [H]

Identifier: 182681211

GI number: 182681211

Start: 778230

End: 780227

Strand: Reverse

Name: cyoB [H]

Synonym: XfasM23_0655

Alternate gene names: 182681211

Gene position: 780227-778230 (Counterclockwise)

Preceding gene: 182681212

Following gene: 182681210

Centisome position: 30.77

GC content: 52.95

Gene sequence:

>1998_bases
ATGTTAGGCAAGCTTTCGTGGGATGCAATCCCCTACGACCCAATCGTTTTGACTGCAGTCGGGGGAGGCGGTCTCGCCAT
CCTAGGGGTCATGATTGCGATCACCTATTTCAAAAAATGGGGGTACTTATGGCGCGAGTGGCTCACTTCGGTCGACCACA
AGAAAATCGGTGTGATGTATATCGTGGTAGCGCTGGTGATGTTGTTACGCGGCTTTGCCGACGCAATATTCATGCGCACC
CAACTGGCCATCGCACATAGCGGTAACGAAGGCATTTTTCCACCGCACCACTACGACCAGATATTTACCGCCCACGGCGT
GATCATGATCTTTTTCATGGCCATGCCACTCATGACAGGCCTACTCAATCTGATCGTACCGCTGCAAATTGGCGCCCGCG
ACGTCGCCTATCCATTTCTTAACTCCCTCAGCTTCTGGCTGTTTGTGGGCGGCGCGGCACTGATCAACATCTCATTGGCT
GTCGGTGAATTTGCACAAACCGGCTGGCTGGCCTACCCGCCACTGTCAGAATTGGAATACAGCCCTGGTGTCGGCGTGGA
CTACTACCTCTGGGCACTGCAAATTTCTGGGTTAGGTACGTTGCTAACTGGCATTAATTTCCTGGTCACGATAATGAGGA
TGCGTGCGCCCGGCATGACCCTGATGCGTATGCCGGTCTTTACCTGGACCGCGCTCATCACCAACATCCTGATCATTGCC
GCATTCCCTATTTTGACCGTCACACTGGCATTGTTGGGTGCTGACCGCTACCTAGGTACACACTTCTTTACCAACGACGG
CGGCGGCAACGCCATGATGTACGTCAATCTGATTTGGATCTGGGGCCACCCTGAGGTCTATATCCTTGCCCTGCCAGCAT
TCGGCATCTACTCCGAATTGGTCGCGACCTACTGCCGCAAGAAGCTATTTGGGTATACCTCAATGGTCTACGCAACCTCA
TGCATCGGCGTCCTGTCGTTTATTGTTTGGCTGCACCACTTTTTCACGATGGGCTCTGGTGCAAACGTCAATGCCTTCTT
TGGCATCACGACGATGATCATCTCGATTCCAACCGGCGTAAAGATATTTAACTGGCTATTCACCATGTATCGTGGCCGAG
TGCATTTCAGCGCCCCGATGTGGTGGACCATCGGTTTCATGATCACCTTCACCATCGGCGGAATGACAGGTGTCATGCTG
GCCATCCCCGCAGTCGACTTCGTGTTACATAACAGCCTGTTCTTGATTGCGCATTTCCATAACACCATCATCGGTGCGGC
CGTGTTCGGTTATTTAGCCGGCATGACGTATTGGTTCCCGAAAGCATTTGGCTTCAAACTCAACGAAACACTGGGCAAAG
CCTCTTTTGCCTGCTGGATCGTCGGTTTCTTCGTCGCGTTTATGCCGTTGTATGCACTCGGCTTCATGGGCATGACCCGT
CGTCTAAATAGCTACAACAACCCGCAATGGGAGCCTTGGTTACTGGTTGCAGCTGGCGGTGCCGTGATTATTGGGATCGG
TATTTTCTTGAATCTGGTGCAATTTGCTTACAGCCTCTGGACACACAAGCAAAACCGCGACCTGACAGGCGACCCCTGGG
ACGGACGCACCCTGGAGTGGTCGACCTCCTCACCACCGCCATTCTACAACTTTGCCCACGTCCCTCATGTGGACAGCTTG
GACCAATTCTGGGAAGACAAACAGCGTGGCAAAGCCTGGAAAAAACCAGACAAATACGAGGATATCCACATGCCACGCAA
CACCGCAGCCGGCTTCTGGATCGGCGCCTTCAGCATCGTTCTGGGCTTCGCTCTGACGTGGCATATCTGGTGGATGGCAA
TACTCGGTCTGGTTGGCATGATCGGTAGCTTCATTGCCCGCAGTTTCGATAACGACATTGATTACTGGGTCCCTGCCGAG
GAAGTGGCTCGTATCGAGAACGAACGCTTCGCACTGCTAGAAAAAGGACAAACAGCACTTGCTGCGAAGGCTGTATAA

Upstream 100 bases:

>100_bases
TGATGGGGCATGGCCACCACGCCGACGATCACGACAATCATCATGAGCACCAGTTATCGCTGGAAGATTCGGTGAGCATG
TGCACTTCTGGAGGCAAACA

Downstream 100 bases:

>100_bases
CCCCTATGCCCATTTCCACAAAGATAGATATGCATAACAGAGATCACGCACATCACGACACTGGAGACAACACCGTCTTC
GGATTTTGGGTTTACCTGAT

Product: cytochrome o ubiquinol oxidase subunit I

Products: NA

Alternate protein names: Cytochrome o subunit 1; Cytochrome o ubiquinol oxidase subunit 1; Oxidase BO(3) subunit 1; Ubiquinol oxidase chain A; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 665; Mature: 665

Protein sequence:

>665_residues
MLGKLSWDAIPYDPIVLTAVGGGGLAILGVMIAITYFKKWGYLWREWLTSVDHKKIGVMYIVVALVMLLRGFADAIFMRT
QLAIAHSGNEGIFPPHHYDQIFTAHGVIMIFFMAMPLMTGLLNLIVPLQIGARDVAYPFLNSLSFWLFVGGAALINISLA
VGEFAQTGWLAYPPLSELEYSPGVGVDYYLWALQISGLGTLLTGINFLVTIMRMRAPGMTLMRMPVFTWTALITNILIIA
AFPILTVTLALLGADRYLGTHFFTNDGGGNAMMYVNLIWIWGHPEVYILALPAFGIYSELVATYCRKKLFGYTSMVYATS
CIGVLSFIVWLHHFFTMGSGANVNAFFGITTMIISIPTGVKIFNWLFTMYRGRVHFSAPMWWTIGFMITFTIGGMTGVML
AIPAVDFVLHNSLFLIAHFHNTIIGAAVFGYLAGMTYWFPKAFGFKLNETLGKASFACWIVGFFVAFMPLYALGFMGMTR
RLNSYNNPQWEPWLLVAAGGAVIIGIGIFLNLVQFAYSLWTHKQNRDLTGDPWDGRTLEWSTSSPPPFYNFAHVPHVDSL
DQFWEDKQRGKAWKKPDKYEDIHMPRNTAAGFWIGAFSIVLGFALTWHIWWMAILGLVGMIGSFIARSFDNDIDYWVPAE
EVARIENERFALLEKGQTALAAKAV

Sequences:

>Translated_665_residues
MLGKLSWDAIPYDPIVLTAVGGGGLAILGVMIAITYFKKWGYLWREWLTSVDHKKIGVMYIVVALVMLLRGFADAIFMRT
QLAIAHSGNEGIFPPHHYDQIFTAHGVIMIFFMAMPLMTGLLNLIVPLQIGARDVAYPFLNSLSFWLFVGGAALINISLA
VGEFAQTGWLAYPPLSELEYSPGVGVDYYLWALQISGLGTLLTGINFLVTIMRMRAPGMTLMRMPVFTWTALITNILIIA
AFPILTVTLALLGADRYLGTHFFTNDGGGNAMMYVNLIWIWGHPEVYILALPAFGIYSELVATYCRKKLFGYTSMVYATS
CIGVLSFIVWLHHFFTMGSGANVNAFFGITTMIISIPTGVKIFNWLFTMYRGRVHFSAPMWWTIGFMITFTIGGMTGVML
AIPAVDFVLHNSLFLIAHFHNTIIGAAVFGYLAGMTYWFPKAFGFKLNETLGKASFACWIVGFFVAFMPLYALGFMGMTR
RLNSYNNPQWEPWLLVAAGGAVIIGIGIFLNLVQFAYSLWTHKQNRDLTGDPWDGRTLEWSTSSPPPFYNFAHVPHVDSL
DQFWEDKQRGKAWKKPDKYEDIHMPRNTAAGFWIGAFSIVLGFALTWHIWWMAILGLVGMIGSFIARSFDNDIDYWVPAE
EVARIENERFALLEKGQTALAAKAV
>Mature_665_residues
MLGKLSWDAIPYDPIVLTAVGGGGLAILGVMIAITYFKKWGYLWREWLTSVDHKKIGVMYIVVALVMLLRGFADAIFMRT
QLAIAHSGNEGIFPPHHYDQIFTAHGVIMIFFMAMPLMTGLLNLIVPLQIGARDVAYPFLNSLSFWLFVGGAALINISLA
VGEFAQTGWLAYPPLSELEYSPGVGVDYYLWALQISGLGTLLTGINFLVTIMRMRAPGMTLMRMPVFTWTALITNILIIA
AFPILTVTLALLGADRYLGTHFFTNDGGGNAMMYVNLIWIWGHPEVYILALPAFGIYSELVATYCRKKLFGYTSMVYATS
CIGVLSFIVWLHHFFTMGSGANVNAFFGITTMIISIPTGVKIFNWLFTMYRGRVHFSAPMWWTIGFMITFTIGGMTGVML
AIPAVDFVLHNSLFLIAHFHNTIIGAAVFGYLAGMTYWFPKAFGFKLNETLGKASFACWIVGFFVAFMPLYALGFMGMTR
RLNSYNNPQWEPWLLVAAGGAVIIGIGIFLNLVQFAYSLWTHKQNRDLTGDPWDGRTLEWSTSSPPPFYNFAHVPHVDSL
DQFWEDKQRGKAWKKPDKYEDIHMPRNTAAGFWIGAFSIVLGFALTWHIWWMAILGLVGMIGSFIARSFDNDIDYWVPAE
EVARIENERFALLEKGQTALAAKAV

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration. This ubiquinol oxidase shows proton pump activity across the membrane in addition to the electron transfer [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=518, Percent_Identity=38.6100386100386, Blast_Score=342, Evalue=7e-94,
Organism=Escherichia coli, GI1786634, Length=660, Percent_Identity=69.5454545454545, Blast_Score=964, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=543, Percent_Identity=36.6482504604052, Blast_Score=339, Evalue=8e-94,
Organism=Saccharomyces cerevisiae, GI6226524, Length=327, Percent_Identity=41.8960244648318, Blast_Score=249, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6226523, Length=277, Percent_Identity=32.8519855595668, Blast_Score=137, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 74432; Mature: 74432

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGKLSWDAIPYDPIVLTAVGGGGLAILGVMIAITYFKKWGYLWREWLTSVDHKKIGVMY
CCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
IVVALVMLLRGFADAIFMRTQLAIAHSGNEGIFPPHHYDQIFTAHGVIMIFFMAMPLMTG
HHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLNLIVPLQIGARDVAYPFLNSLSFWLFVGGAALINISLAVGEFAQTGWLAYPPLSELEY
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHEEEEHHHHHHHHCCCEECCCHHHCCC
SPGVGVDYYLWALQISGLGTLLTGINFLVTIMRMRAPGMTLMRMPVFTWTALITNILIIA
CCCCCHHHEEEEHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
AFPILTVTLALLGADRYLGTHFFTNDGGGNAMMYVNLIWIWGHPEVYILALPAFGIYSEL
HHHHHHHHHHHHHCHHHHCCEEEECCCCCCEEEEEEEEEEECCCCEEEEEECCHHHHHHH
VATYCRKKLFGYTSMVYATSCIGVLSFIVWLHHFFTMGSGANVNAFFGITTMIISIPTGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCH
KIFNWLFTMYRGRVHFSAPMWWTIGFMITFTIGGMTGVMLAIPAVDFVLHNSLFLIAHFH
HHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEHHH
NTIIGAAVFGYLAGMTYWFPKAFGFKLNETLGKASFACWIVGFFVAFMPLYALGFMGMTR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLNSYNNPQWEPWLLVAAGGAVIIGIGIFLNLVQFAYSLWTHKQNRDLTGDPWDGRTLEW
HHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEE
STSSPPPFYNFAHVPHVDSLDQFWEDKQRGKAWKKPDKYEDIHMPRNTAAGFWIGAFSIV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LGFALTWHIWWMAILGLVGMIGSFIARSFDNDIDYWVPAEEVARIENERFALLEKGQTAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHCCCHHH
AAKAV
HHCCC
>Mature Secondary Structure
MLGKLSWDAIPYDPIVLTAVGGGGLAILGVMIAITYFKKWGYLWREWLTSVDHKKIGVMY
CCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
IVVALVMLLRGFADAIFMRTQLAIAHSGNEGIFPPHHYDQIFTAHGVIMIFFMAMPLMTG
HHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLNLIVPLQIGARDVAYPFLNSLSFWLFVGGAALINISLAVGEFAQTGWLAYPPLSELEY
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHEEEEHHHHHHHHCCCEECCCHHHCCC
SPGVGVDYYLWALQISGLGTLLTGINFLVTIMRMRAPGMTLMRMPVFTWTALITNILIIA
CCCCCHHHEEEEHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
AFPILTVTLALLGADRYLGTHFFTNDGGGNAMMYVNLIWIWGHPEVYILALPAFGIYSEL
HHHHHHHHHHHHHCHHHHCCEEEECCCCCCEEEEEEEEEEECCCCEEEEEECCHHHHHHH
VATYCRKKLFGYTSMVYATSCIGVLSFIVWLHHFFTMGSGANVNAFFGITTMIISIPTGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCH
KIFNWLFTMYRGRVHFSAPMWWTIGFMITFTIGGMTGVMLAIPAVDFVLHNSLFLIAHFH
HHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEHHH
NTIIGAAVFGYLAGMTYWFPKAFGFKLNETLGKASFACWIVGFFVAFMPLYALGFMGMTR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLNSYNNPQWEPWLLVAAGGAVIIGIGIFLNLVQFAYSLWTHKQNRDLTGDPWDGRTLEW
HHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEE
STSSPPPFYNFAHVPHVDSLDQFWEDKQRGKAWKKPDKYEDIHMPRNTAAGFWIGAFSIV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LGFALTWHIWWMAILGLVGMIGSFIARSFDNDIDYWVPAEEVARIENERFALLEKGQTAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHCCCHHH
AAKAV
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]