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The map label for this gene is frr

Identifier: 182680889

GI number: 182680889

Start: 424366

End: 424938

Strand: Reverse

Name: frr

Synonym: XfasM23_0327

Alternate gene names: 182680889

Gene position: 424938-424366 (Counterclockwise)

Preceding gene: 182680890

Following gene: 182680888

Centisome position: 16.76

GC content: 49.74

Gene sequence:

>573_bases
ATGAACATTCAGGCGATGCTCAACCAAATCAAACAAGACGCTCAGGATCGCATGACAAAGAGCATTGACGCTCTACGCAA
CTCCCTGGCATCTGTACGTACTGGCCGGGCTTCGCCATCACTATTGGATGGCATCAAAATCAAGGCTTACGGTACCGATA
CACCATTGAATCAGGTCGCCAGCATCAGTGTCTCAGAAGGACGCTCATTGGTCATCACGGTGTTCGACAAAAATATGTCC
AAGGACGTTGAGAAAGCAATTTATGCTTCCGACCTTGGCCTGACACCAACCGTTGTTGGCACATTGATCCGCCTCAACCT
GCCACCACTCACTGAGGAGCGCCGTAAGGAACTCACAAAAGTCGTGCACAGCGAGGGAGAGGACACCAAAGTCGCAATCC
GCAATATCCGCCGCGACGCCAATCAGCAGATTAAGGATATGCTAAAGAGCAAGGAAATCACTGAAGACGAAGTACGCCAC
GGTGAAGAAGACATCCAGAAGCTGACCGATAAAGCAATCAAAAGCGTGGATGAGGTAGTCAAGTCCAAAGAACAGGAATT
GATGACGGTCTGA

Upstream 100 bases:

>100_bases
AGGAAGAACGTTTAGGAATTCACCAGAAAAAGAGCTTGGATCACCCCCTCAGCACCACAAGCACCAGTCCCAGCTATAAT
CGGTCAACTACGCTTTATCA

Downstream 100 bases:

>100_bases
AGATGCAGATCAACACCATACCAGTCAATCCCACACTTCCCCGCCACATAGCCATCATCATGGATGGTAACGGGCGCTGG
GCAGAACGCCGATCACGGCC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MNIQAMLNQIKQDAQDRMTKSIDALRNSLASVRTGRASPSLLDGIKIKAYGTDTPLNQVASISVSEGRSLVITVFDKNMS
KDVEKAIYASDLGLTPTVVGTLIRLNLPPLTEERRKELTKVVHSEGEDTKVAIRNIRRDANQQIKDMLKSKEITEDEVRH
GEEDIQKLTDKAIKSVDEVVKSKEQELMTV

Sequences:

>Translated_190_residues
MNIQAMLNQIKQDAQDRMTKSIDALRNSLASVRTGRASPSLLDGIKIKAYGTDTPLNQVASISVSEGRSLVITVFDKNMS
KDVEKAIYASDLGLTPTVVGTLIRLNLPPLTEERRKELTKVVHSEGEDTKVAIRNIRRDANQQIKDMLKSKEITEDEVRH
GEEDIQKLTDKAIKSVDEVVKSKEQELMTV
>Mature_190_residues
MNIQAMLNQIKQDAQDRMTKSIDALRNSLASVRTGRASPSLLDGIKIKAYGTDTPLNQVASISVSEGRSLVITVFDKNMS
KDVEKAIYASDLGLTPTVVGTLIRLNLPPLTEERRKELTKVVHSEGEDTKVAIRNIRRDANQQIKDMLKSKEITEDEVRH
GEEDIQKLTDKAIKSVDEVVKSKEQELMTV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=180, Percent_Identity=28.3333333333333, Blast_Score=70, Evalue=9e-13,
Organism=Escherichia coli, GI1786368, Length=183, Percent_Identity=55.7377049180328, Blast_Score=216, Evalue=9e-58,
Organism=Drosophila melanogaster, GI24661488, Length=174, Percent_Identity=25.2873563218391, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 21188; Mature: 21188

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIQAMLNQIKQDAQDRMTKSIDALRNSLASVRTGRASPSLLDGIKIKAYGTDTPLNQVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCEEEEECCCCCHHHHH
SISVSEGRSLVITVFDKNMSKDVEKAIYASDLGLTPTVVGTLIRLNLPPLTEERRKELTK
HHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHH
VVHSEGEDTKVAIRNIRRDANQQIKDMLKSKEITEDEVRHGEEDIQKLTDKAIKSVDEVV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHH
KSKEQELMTV
HHHHHHHCCC
>Mature Secondary Structure
MNIQAMLNQIKQDAQDRMTKSIDALRNSLASVRTGRASPSLLDGIKIKAYGTDTPLNQVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCEEEEECCCCCHHHHH
SISVSEGRSLVITVFDKNMSKDVEKAIYASDLGLTPTVVGTLIRLNLPPLTEERRKELTK
HHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHH
VVHSEGEDTKVAIRNIRRDANQQIKDMLKSKEITEDEVRHGEEDIQKLTDKAIKSVDEVV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHH
KSKEQELMTV
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]