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The map label for this gene is lpxA [H]

Identifier: 182680881

GI number: 182680881

Start: 415247

End: 416050

Strand: Reverse

Name: lpxA [H]

Synonym: XfasM23_0319

Alternate gene names: 182680881

Gene position: 416050-415247 (Counterclockwise)

Preceding gene: 182680882

Following gene: 182680880

Centisome position: 16.41

GC content: 51.99

Gene sequence:

>804_bases
ATGGAAGCAGTGATGAATAAGCATGCGTCCTTGATCCACCCAACCGCAGTGATCGCTCCATCGGCCACGTTAGCCCCAGA
CGTACAGATTGGTGCCTTTACATTGATCGGTAACGACGTGCAAATAGACACAGGTACGATCATCGGATCACATTGCACTA
TTCACGGTCCCACCAGGATCGGGCGTAATAACCGATTCATTGGTCAAGCCGCGATTGGCGGCGAACCACAAGACAAAAAG
TTCGCAGGCGAGCGCACCGAACTACTGATCGGCGATAACAACACCATCCGCGAATTCGTCACTATCAACCGTGGCACTGG
CGGTGGTGGTGGTGTCACATCAATTGGCAATGACAACTGGATACTGGCGTATACCCATATCGCTCACGACTGCCACGTCG
GTCACCACTGTGTATTCTCCAACAACGCCTCGCTGGCTGGTCACGTCACCGTCGGTGACTGGGTGATCTTCAGTGGCTTC
TCTGGCGCACATCAATTTTGCCGAATCGGAAGATATGCCTTCATCGGCATGGGAACATTGATTAATGGCGACGTACCACC
GTTCACCTTAATTGGTAGCGATACCCTTGGTCGTCCAAGGGGCATCAATAATGAAGGATTGAAACGGCGCAACTTCACTC
CAGAACGCATCACCGCCATCAAACGCGCTTATCGCACCTTATACGTAGCCGGACTACCACTGGCTGAAGCAAAACAGCAA
CTCGCTGAACAAGCCAAAGACAACGACGACATCAAAGAACTCCTCCAATTCATCGAGACAGCGCAAAGGCCGCTACTACG
ATGA

Upstream 100 bases:

>100_bases
CCGCAATATGGGCTGCTACTACGGCGAAGCGCGGGTTAACGGCGAAGTCGTCGCTTGCGCTGATATCATGTGTGCTGGTG
TCAAGTCTTAAGCGCCCAGT

Downstream 100 bases:

>100_bases
GCTCAACCTCAAAGCAGAAGATACCCACCGATACCCCGTTACCGCACACCAAACTGACTTACCACGGCACCTTGACATGA
TCCAAGCGCCCCGCATCGCA

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MEAVMNKHASLIHPTAVIAPSATLAPDVQIGAFTLIGNDVQIDTGTIIGSHCTIHGPTRIGRNNRFIGQAAIGGEPQDKK
FAGERTELLIGDNNTIREFVTINRGTGGGGGVTSIGNDNWILAYTHIAHDCHVGHHCVFSNNASLAGHVTVGDWVIFSGF
SGAHQFCRIGRYAFIGMGTLINGDVPPFTLIGSDTLGRPRGINNEGLKRRNFTPERITAIKRAYRTLYVAGLPLAEAKQQ
LAEQAKDNDDIKELLQFIETAQRPLLR

Sequences:

>Translated_267_residues
MEAVMNKHASLIHPTAVIAPSATLAPDVQIGAFTLIGNDVQIDTGTIIGSHCTIHGPTRIGRNNRFIGQAAIGGEPQDKK
FAGERTELLIGDNNTIREFVTINRGTGGGGGVTSIGNDNWILAYTHIAHDCHVGHHCVFSNNASLAGHVTVGDWVIFSGF
SGAHQFCRIGRYAFIGMGTLINGDVPPFTLIGSDTLGRPRGINNEGLKRRNFTPERITAIKRAYRTLYVAGLPLAEAKQQ
LAEQAKDNDDIKELLQFIETAQRPLLR
>Mature_267_residues
MEAVMNKHASLIHPTAVIAPSATLAPDVQIGAFTLIGNDVQIDTGTIIGSHCTIHGPTRIGRNNRFIGQAAIGGEPQDKK
FAGERTELLIGDNNTIREFVTINRGTGGGGGVTSIGNDNWILAYTHIAHDCHVGHHCVFSNNASLAGHVTVGDWVIFSGF
SGAHQFCRIGRYAFIGMGTLINGDVPPFTLIGSDTLGRPRGINNEGLKRRNFTPERITAIKRAYRTLYVAGLPLAEAKQQ
LAEQAKDNDDIKELLQFIETAQRPLLR

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=263, Percent_Identity=43.7262357414449, Blast_Score=230, Evalue=8e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 28829; Mature: 28829

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAVMNKHASLIHPTAVIAPSATLAPDVQIGAFTLIGNDVQIDTGTIIGSHCTIHGPTRI
CCCHHHHCCHHCCCCEEECCCCCCCCCCEEEEEEEECCEEEEECCEEEECCEEEECCHHC
GRNNRFIGQAAIGGEPQDKKFAGERTELLIGDNNTIREFVTINRGTGGGGGVTSIGNDNW
CCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCE
ILAYTHIAHDCHVGHHCVFSNNASLAGHVTVGDWVIFSGFSGAHQFCRIGRYAFIGMGTL
EEEEEEECCCCCCCCEEEEECCCCEEEEEEECCEEEECCCCHHHHHHHHCCEEEEEECEE
INGDVPPFTLIGSDTLGRPRGINNEGLKRRNFTPERITAIKRAYRTLYVAGLPLAEAKQQ
ECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEECCCHHHHHHH
LAEQAKDNDDIKELLQFIETAQRPLLR
HHHHCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEAVMNKHASLIHPTAVIAPSATLAPDVQIGAFTLIGNDVQIDTGTIIGSHCTIHGPTRI
CCCHHHHCCHHCCCCEEECCCCCCCCCCEEEEEEEECCEEEEECCEEEECCEEEECCHHC
GRNNRFIGQAAIGGEPQDKKFAGERTELLIGDNNTIREFVTINRGTGGGGGVTSIGNDNW
CCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCE
ILAYTHIAHDCHVGHHCVFSNNASLAGHVTVGDWVIFSGFSGAHQFCRIGRYAFIGMGTL
EEEEEEECCCCCCCCEEEEECCCCEEEEEEECCEEEECCCCHHHHHHHHCCEEEEEECEE
INGDVPPFTLIGSDTLGRPRGINNEGLKRRNFTPERITAIKRAYRTLYVAGLPLAEAKQQ
ECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEECCCHHHHHHH
LAEQAKDNDDIKELLQFIETAQRPLLR
HHHHCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]